[go: up one dir, main page]

SG11202000415PA - Transdermal delivery system with a microporous membrane having solvent-filled pores - Google Patents

Transdermal delivery system with a microporous membrane having solvent-filled pores

Info

Publication number
SG11202000415PA
SG11202000415PA SG11202000415PA SG11202000415PA SG11202000415PA SG 11202000415P A SG11202000415P A SG 11202000415PA SG 11202000415P A SG11202000415P A SG 11202000415PA SG 11202000415P A SG11202000415P A SG 11202000415PA SG 11202000415P A SG11202000415P A SG 11202000415PA
Authority
SG
Singapore
Prior art keywords
solvent
delivery system
microporous membrane
transdermal delivery
filled pores
Prior art date
Application number
SG11202000415PA
Inventor
Eun Soo Lee
Amit K Jain
Parminder Singh
Original Assignee
Corium Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corium Inc filed Critical Corium Inc
Publication of SG11202000415PA publication Critical patent/SG11202000415PA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061Polyacrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
SG11202000415PA 2017-07-26 2018-07-26 Transdermal delivery system with a microporous membrane having solvent-filled pores SG11202000415PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762537414P 2017-07-26 2017-07-26
PCT/US2018/043961 WO2019023499A1 (en) 2017-07-26 2018-07-26 Transdermal delivery system with a microporous membrane having solvent-filled pores

Publications (1)

Publication Number Publication Date
SG11202000415PA true SG11202000415PA (en) 2020-02-27

Family

ID=63165550

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202000415PA SG11202000415PA (en) 2017-07-26 2018-07-26 Transdermal delivery system with a microporous membrane having solvent-filled pores

Country Status (10)

Country Link
US (2) US20190029971A1 (en)
EP (1) EP3658127A1 (en)
JP (2) JP2020529229A (en)
KR (1) KR102904873B1 (en)
CN (1) CN111132669A (en)
AU (1) AU2018307792B2 (en)
CA (1) CA3071007A1 (en)
MX (1) MX2020000651A (en)
SG (1) SG11202000415PA (en)
WO (1) WO2019023499A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2018008190A (en) 2015-12-30 2018-11-12 Corium Int Inc Systems and methods for long term transdermal administration.
WO2017223402A1 (en) 2016-06-23 2017-12-28 Corium International, Inc. Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent
KR102555208B1 (en) 2016-07-27 2023-07-17 코리움, 엘엘씨 Sodium bicarbonate in situ conversion driven transdermal delivery of amine drug
WO2018022818A1 (en) 2016-07-27 2018-02-01 Corium International, Inc. Memantine transdermal delivery systems
JP2020529229A (en) * 2017-07-26 2020-10-08 コリウム, インコーポレイテッド Percutaneous delivery system with microporous membranes with solvent-filled pores
AU2018392686A1 (en) 2017-12-20 2020-07-09 Corium Pharma Solutions, Inc. Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point
US20230233480A1 (en) * 2019-10-24 2023-07-27 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system for the transdermal administration of fingolimod
US12390542B2 (en) * 2020-06-05 2025-08-19 Roxilla Llc On-demand agent dispensing devices and related methods
US20230072739A1 (en) 2021-06-28 2023-03-09 Corium, Llc Combination therapy treatment using transdermal delivery system
EP4362921A2 (en) 2021-06-28 2024-05-08 Corium, LLC Corona discharge treated transdermal delivery system
WO2024145319A1 (en) * 2022-12-28 2024-07-04 Corium, Llc Method of preparing transdermal delivery system
IL321722A (en) * 2022-12-28 2025-08-01 Corium Llc Pre-mixing method of preparing transdermal delivery system
WO2025103446A1 (en) * 2023-11-16 2025-05-22 宜昌人福药业有限责任公司 Transdermal patch containing donepezil and preparation method therefor

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4756710A (en) * 1985-04-05 1988-07-12 Merck & Co., Inc. pH-Mediated drug delivery system
US4880633A (en) * 1986-03-12 1989-11-14 Merck & Co., Inc. Transdermal drug delivery system
US4849224A (en) * 1987-11-12 1989-07-18 Theratech Inc. Device for administering an active agent to the skin or mucosa
JPH06199659A (en) * 1992-10-28 1994-07-19 Hisamitsu Pharmaceut Co Inc Apparatus for percutaneous treatment
US5635203A (en) * 1994-09-29 1997-06-03 Alza Corporation Transdermal device having decreased delamination
WO1996019205A1 (en) * 1994-12-21 1996-06-27 Theratech, Inc. Transdermal delivery system with adhesive overlay and peel seal disc
MXPA02000053A (en) * 1999-07-05 2003-07-21 Idea Ag A method for the improvement of transport across adaptable semi-permeable barriers.
US20020192243A1 (en) * 1999-12-16 2002-12-19 Tsung-Min Hsu Transdermal and topical administration of drugs for the treatment of Alzheimer's disease using basic enhancers
WO2002087645A1 (en) 2001-05-01 2002-11-07 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions
ATE399026T1 (en) 2003-11-21 2008-07-15 Memory Pharm Corp COMPOSITIONS CONTAINING L-TYPE CALCIUM CANAL BLOCKERS AND CHOLINESTERASE INHIBITORS
AU2006343077B2 (en) * 2006-05-08 2012-11-08 Teikoku Seiyaku Co., Ltd. Tansdermally absorbable preparation comprising anti-dementia agent
US9248104B2 (en) * 2006-08-17 2016-02-02 Core Tech Solutions, Inc. Transdermal methods and systems for treating Alzheimer's disease
CN101605546B (en) * 2006-12-01 2011-12-14 日东电工株式会社 Method for prevention of discoloration with time of donepezil-containing skin adhesive preparation
DE102008013701A1 (en) * 2008-03-11 2009-09-17 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system with stabilized membrane
KR101454362B1 (en) * 2008-03-24 2014-10-23 아이큐어 주식회사 Transdermal preparation for the treatment of dementia comprising donepezil as an active ingredient
US20090291127A1 (en) * 2008-05-21 2009-11-26 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
CN102630160B (en) * 2009-09-16 2014-05-07 株式会社三养生物制药 Transdermal delivery system, method for manufacturing the same, and transdermal delivery method using the system
US20100178307A1 (en) * 2010-01-13 2010-07-15 Jianye Wen Transdermal anti-dementia active agent formulations and methods for using the same
JP5699554B2 (en) 2010-11-11 2015-04-15 富士通株式会社 Vector processing circuit, instruction issue control method, and processor system
HUE048569T2 (en) * 2014-12-18 2020-07-28 Icure Pharm Inc Transdermal preparation containing donepezil as active ingredient
CN108135860A (en) * 2015-06-22 2018-06-08 考里安国际公司 Transdermal adhesive composition comprising a poorly soluble therapeutic agent
MX2018008190A (en) * 2015-12-30 2018-11-12 Corium Int Inc Systems and methods for long term transdermal administration.
KR102555208B1 (en) * 2016-07-27 2023-07-17 코리움, 엘엘씨 Sodium bicarbonate in situ conversion driven transdermal delivery of amine drug
JP2020529229A (en) 2017-07-26 2020-10-08 コリウム, インコーポレイテッド Percutaneous delivery system with microporous membranes with solvent-filled pores

Also Published As

Publication number Publication date
US20240016759A1 (en) 2024-01-18
KR102904873B1 (en) 2025-12-29
JP2023171749A (en) 2023-12-05
MX2020000651A (en) 2020-07-29
CA3071007A1 (en) 2019-01-31
JP7611327B2 (en) 2025-01-09
EP3658127A1 (en) 2020-06-03
KR20200032153A (en) 2020-03-25
WO2019023499A1 (en) 2019-01-31
RU2020108005A3 (en) 2021-11-30
JP2020529229A (en) 2020-10-08
CN111132669A (en) 2020-05-08
AU2018307792B2 (en) 2024-08-08
AU2018307792A1 (en) 2020-02-06
RU2020108005A (en) 2021-08-26
US20190029971A1 (en) 2019-01-31

Similar Documents

Publication Publication Date Title
SG11202000415PA (en) Transdermal delivery system with a microporous membrane having solvent-filled pores
GB201805261D0 (en) Membranes
SG11201701531WA (en) Porous membrane
GB201719767D0 (en) Membrane
GB2571428B (en) GC-IMS interface comprising semi-permeable membrane for blocking transmission
GB201707122D0 (en) Pore
EP3328310A4 (en) Sub-atmospheric wound therapy systems and methods
GB201721320D0 (en) Membrane
SG10201504770TA (en) Hydrophilic block copolymers and membranes prepared therefrom (ii)
EP3162431A4 (en) Composite semipermeable membrane
IL258025B (en) A drip emitter and a membrane for a drip emitter
GB201701406D0 (en) Membrane
EP3349737A4 (en) Transdermal delivery system
EP3252855A4 (en) Porous carbon sheet and precursor fiber sheet thereof
EP3162432A4 (en) Composite semipermeable membrane
SG10201504716UA (en) Hydrophilic block copolymers and membranes prepared therefrom (i)
EP3238815A4 (en) Composite semipermeable membrane
HUE051691T2 (en) Porous hollow fiber membrane
GB201505964D0 (en) Composite membrane
PT3242552T (en) Gas delivery device comprising a gas releasing molecule and a gas permeable membrane
EP3225299A4 (en) Multilayer semipermeable membrane
EP3246085A4 (en) Porous hollow fiber membrane
GB201510648D0 (en) Composite membranes
HUE072725T2 (en) Membrane support and membrane filtration device
GB201604949D0 (en) Composite membranes