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SG11201909305PA - Cold slurry containment - Google Patents

Cold slurry containment

Info

Publication number
SG11201909305PA
SG11201909305PA SG11201909305PA SG11201909305PA SG 11201909305P A SG11201909305P A SG 11201909305PA SG 11201909305P A SG11201909305P A SG 11201909305PA SG 11201909305P A SG11201909305P A SG 11201909305PA
Authority
SG
Singapore
Prior art keywords
international
cold slurry
pct
winthrop
cambridge
Prior art date
Application number
Inventor
Christopher Velis
Original Assignee
Miraki Innovation Think Tank Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miraki Innovation Think Tank Llc filed Critical Miraki Innovation Think Tank Llc
Publication of SG11201909305PA publication Critical patent/SG11201909305PA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A61F7/123—Devices for heating or cooling internal body cavities using a flexible balloon containing the thermal element
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/007—Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1002—Balloon catheters characterised by balloon shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/04—Protection of tissue around surgical sites against effects of non-mechanical surgery, e.g. laser surgery
    • A61B2090/0463—Protection of tissue around surgical sites against effects of non-mechanical surgery, e.g. laser surgery against cooling or freezing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0054—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water
    • A61F2007/0056—Heating or cooling appliances for medical or therapeutic treatment of the human body with a closed fluid circuit, e.g. hot water for cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0059—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit
    • A61F2007/0063—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit for cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0059—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit
    • A61F2007/0069—Heating or cooling appliances for medical or therapeutic treatment of the human body with an open fluid circuit with return means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0091—Heating or cooling appliances for medical or therapeutic treatment of the human body inflatable
    • A61F2007/0092—Heating or cooling appliances for medical or therapeutic treatment of the human body inflatable with, or also with, a substance other than air
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F2007/0095—Heating or cooling appliances for medical or therapeutic treatment of the human body with a temperature indicator
    • A61F2007/0096—Heating or cooling appliances for medical or therapeutic treatment of the human body with a temperature indicator with a thermometer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F2007/0244—Compresses or poultices for effecting heating or cooling with layers
    • A61F2007/0249—Compresses or poultices for effecting heating or cooling with layers with a layer having low heat transfer capability
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F2007/0244—Compresses or poultices for effecting heating or cooling with layers
    • A61F2007/0249—Compresses or poultices for effecting heating or cooling with layers with a layer having low heat transfer capability
    • A61F2007/025—Compresses or poultices for effecting heating or cooling with layers with a layer having low heat transfer capability retaining air or other gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F2007/0244—Compresses or poultices for effecting heating or cooling with layers
    • A61F2007/0249—Compresses or poultices for effecting heating or cooling with layers with a layer having low heat transfer capability
    • A61F2007/0253—Compresses or poultices for effecting heating or cooling with layers with a layer having low heat transfer capability using a substance with low conductivity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F2007/0282—Compresses or poultices for effecting heating or cooling for particular medical treatments or effects
    • A61F2007/0288—Compresses or poultices for effecting heating or cooling for particular medical treatments or effects during operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/02—Compresses or poultices for effecting heating or cooling
    • A61F2007/0282—Compresses or poultices for effecting heating or cooling for particular medical treatments or effects
    • A61F2007/029—Fat cell removal or destruction by non-ablative heat treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A61F7/12—Devices for heating or cooling internal body cavities
    • A61F2007/126—Devices for heating or cooling internal body cavities for invasive application, e.g. for introducing into blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1011—Multiple balloon catheters
    • A61M2025/1013—Multiple balloon catheters with concentrically mounted balloons, e.g. being independently inflatable
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/1072—Balloon catheters with special features or adapted for special applications having balloons with two or more compartments

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Thermal Sciences (AREA)
  • Vascular Medicine (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Pens And Brushes (AREA)

Abstract

INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 11 October 2018 (11.10.2018) WIPO PCT oimitia °nolo mo mum im oinio oimIE (10) International Publication Number WO 2018/187581 Al GC N GC 00 O N C (51) International Patent Classification: A61B 18/02 (2006.01) (21) International Application Number: PCT/US2018/026273 (22) International Filing Date: 05 April 2018 (05.04.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/482,008 05 April 2017 (05.04.2017) US (71) Applicant: ARCTIC FOX BIOMEDICAL, INC. [US/US]; 97 Winthrop Street, Harvard Square, Cambridge, MA 02138 (US). (72) Inventor: VELIS, Christopher, J.P.; 97 Winthrop Street, Harvard Square, Cambridge, MA 02138 (US). (74) Agent: MEYERS, Thomas C. et al.; Brown Rudnick LLP, One Financial Center, Boston, MA 02111 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). = (54) Title: COLD SLURRY CONTAINMENT 110 FIG. 1 (57) : The present invention provides methods and devices for controlling a cold slurry that is delivered to a target tissue and for limiting heat transferring from surrounding tissue to the target tissue. In particular, a balloon structure is deployed at or near a point of delivery to act as a physical and/or thermal barrier. In some instances, the balloon structure can act as a pressure device obstructing the flow of warm blood into a treatment area, which can melt the cold slurry. [Continued on next page] WO 2018/187581 Al MIDEDIMOM0101011EFIEDMOIE11111111H11111011111110110111111 Published: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h))
SG11201909305P 2017-04-05 2018-04-05 Cold slurry containment SG11201909305PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762482008P 2017-04-05 2017-04-05
PCT/US2018/026273 WO2018187581A1 (en) 2017-04-05 2018-04-05 Cold slurry containment

Publications (1)

Publication Number Publication Date
SG11201909305PA true SG11201909305PA (en) 2019-11-28

Family

ID=63710485

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201909305P SG11201909305PA (en) 2017-04-05 2018-04-05 Cold slurry containment

Country Status (13)

Country Link
US (2) US11446178B2 (en)
EP (1) EP3606456A4 (en)
JP (3) JP7085762B2 (en)
KR (1) KR102589816B1 (en)
CN (1) CN110913781A (en)
AU (1) AU2018249540A1 (en)
BR (1) BR112019020969A8 (en)
CA (1) CA3059296A1 (en)
IL (1) IL269851A (en)
MX (1) MX2019011996A (en)
SG (1) SG11201909305PA (en)
WO (1) WO2018187581A1 (en)
ZA (1) ZA201907137B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2825624C (en) 2011-01-27 2020-01-14 Osa Holdings, Inc. Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
AU2015308794A1 (en) 2014-08-28 2017-03-02 The General Hospital Corporation Injectable slurries and methods of manufacturing and using the same
US11504322B2 (en) 2014-08-28 2022-11-22 The General Hospital Corporation Injectable slurries and methods of manufacturing the same
CA3059294A1 (en) 2017-04-05 2018-10-11 Miraki Innovation Think Tank Llc Point of delivery cold slurry generation
US10500342B2 (en) 2017-08-21 2019-12-10 Miraki Innovation Think Tank Llc Cold slurry syringe
EP3952803A4 (en) 2019-04-10 2023-01-18 Arktikus LLC Cooling and refrigeration based on vacuum-driven water evaporation
WO2021247843A1 (en) 2020-06-05 2021-12-09 Miraki Innovation Think Tank Llc Systems for reducing fat and improving the appearance of skin using multiple modalities
KR102784926B1 (en) 2020-07-10 2025-03-25 씨° 체인지 서지컬 엘엘씨 Injectable slush supply
WO2023278891A1 (en) * 2021-07-02 2023-01-05 Miraki Innovation Think Tank Llc Compositions, systems and methods for treating suprapubic fat
CA3243280A1 (en) 2021-12-30 2023-07-06 Cryosa, Inc. Systems and methods for treatment of obstructive sleep apnea

Family Cites Families (182)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3373906A (en) 1967-02-10 1968-03-19 Haart Inc De Syringe with stirrer
US3893834A (en) 1974-03-04 1975-07-08 Arthur E Armstrong Insulated cold pack
US4354507A (en) 1978-01-17 1982-10-19 Concord Laboratories Syringe
US4619678A (en) 1983-12-20 1986-10-28 Howard Rubin Apparatus and method for transporting and preserving perishable test samples
US4983045A (en) 1985-11-22 1991-01-08 Reica Corporation Mixer
DE3609672A1 (en) 1986-03-21 1987-09-24 Klaus Draenert EVACUABLE BONE CEMENT SYRINGE
IL78755A0 (en) * 1986-05-12 1986-08-31 Biodan Medical Systems Ltd Applicator for insertion into a body opening for medical purposes
US5143063A (en) 1988-02-09 1992-09-01 Fellner Donald G Method of removing adipose tissue from the body
JP2512095B2 (en) 1988-08-12 1996-07-03 株式会社日立製作所 Cold heat generation method
EP0418979A3 (en) 1989-09-21 1992-03-04 Michele Dr. Zocchi Method and apparatus for producing human autologous collagen
US5071040A (en) 1990-03-09 1991-12-10 Pfizer Hospital Products Group, Inc. Surgical adhesives mixing and dispensing implement
US5304128A (en) 1992-09-22 1994-04-19 Habley Medical Technology Corporation Gas powered self contained syringe
US5445523A (en) 1993-09-03 1995-08-29 Ultradent Products, Inc. Syringe apparatus and methods for dispensing viscous materials
US5507790A (en) 1994-03-21 1996-04-16 Weiss; William V. Method of non-invasive reduction of human site-specific subcutaneous fat tissue deposits by accelerated lipolysis metabolism
US5769879A (en) 1995-06-07 1998-06-23 Medical Contouring Corporation Microwave applicator and method of operation
US6464697B1 (en) 1998-02-19 2002-10-15 Curon Medical, Inc. Stomach and adjoining tissue regions in the esophagus
CN1133410C (en) 1996-10-23 2004-01-07 H·G·沃尔塞 cooling bag
US5910104A (en) 1996-12-26 1999-06-08 Cryogen, Inc. Cryosurgical probe with disposable sheath
WO1998041157A1 (en) 1997-03-17 1998-09-24 Boris Rubinsky Freezing method for controlled removal of fatty tissue by liposuction
US6041787A (en) 1997-03-17 2000-03-28 Rubinsky; Boris Use of cryoprotective agent compounds during cryosurgery
GB2338428A (en) 1998-06-19 1999-12-22 David Grant A syringe with an agitator whose shaft passes through a slidable dispensing plunger
US6458109B1 (en) 1998-08-07 2002-10-01 Hill-Rom Services, Inc. Wound treatment apparatus
US6428563B1 (en) 2000-01-21 2002-08-06 Radiant Medical, Inc. Heat exchange catheter with improved insulated region
US6300130B1 (en) 1998-11-16 2001-10-09 The General Hospital Corporation And University Of Massachusetts Ultra rapid freezing for cell cryopreservation
US6403376B1 (en) 1998-11-16 2002-06-11 General Hospital Corporation Ultra rapid freezing for cell cryopreservation
US6324863B1 (en) 1999-03-05 2001-12-04 Imi Cornelius Inc. Sanitary ice making system
US6575930B1 (en) 1999-03-12 2003-06-10 Medrad, Inc. Agitation devices and dispensing systems incorporating such agitation devices
US6334328B1 (en) 1999-03-12 2002-01-01 Imi Cornelius Inc. Sanitary ice making and dispensing apparatus
JP2000325388A (en) * 1999-05-14 2000-11-28 Etsuro Nakarai Celom heating and cooling baloon
JP3111219B1 (en) 1999-05-25 2000-11-20 工業技術院長 Cold heat transport method and apparatus using polyvinyl alcohol
JP2003500097A (en) * 1999-05-25 2003-01-07 チン，ダグラス・オゥ Cryosurgical probe with insulated and heated sheath
US6413444B1 (en) 1999-08-02 2002-07-02 The University Of Chicago Methods and apparatus for producing phase change ice particulate saline slurries
US6547811B1 (en) 1999-08-02 2003-04-15 Arch Development Corporation Method for inducing hypothermia
US6244052B1 (en) 1999-08-02 2001-06-12 The University Of Chicago Method and apparatus for producing phase change ice particulate perfluorocarbon slurries
US6962601B2 (en) 1999-08-02 2005-11-08 University Of Chicago Office Of Technology Transfer Method for inducing hypothermia
US7422601B2 (en) 1999-08-02 2008-09-09 University Of Chicago Office Of Technology Transfer Method for inducing hypothermia
WO2001010482A1 (en) 1999-08-05 2001-02-15 Biocardia, Inc. A system and method for delivering thermally sensitive and reverse-thermal gelation matrials
US6231594B1 (en) 1999-08-11 2001-05-15 Radiant Medical, Inc. Method of controlling body temperature while reducing shivering
US6575966B2 (en) 1999-08-23 2003-06-10 Cryocath Technologies Inc. Endovascular cryotreatment catheter
EP1110599B1 (en) 1999-12-23 2003-04-09 Ernst Mühlbauer GmbH & Co.KG Dynamic mixer for dental impression pastes
US20040220559A1 (en) * 2000-03-01 2004-11-04 Kramer Hans W. Preparation of working fluid for use in cryotherapies
CA2404430A1 (en) 2000-04-07 2001-10-18 Albert S. Lee Methods and apparatus for thermally affecting tissue
US20020045156A1 (en) 2000-05-16 2002-04-18 Mehmet Toner Microinjection of cryoprotectants for preservation of cells
US7255865B2 (en) 2000-12-05 2007-08-14 Allergan, Inc. Methods of administering botulinum toxin
DE60202764D1 (en) 2001-03-27 2005-03-03 Skaginn Hf Akranes METHOD AND DEVICE FOR PRODUCING LIQUID
US6547432B2 (en) 2001-07-16 2003-04-15 Stryker Instruments Bone cement mixing and delivery device for injection and method thereof
US20030032996A1 (en) 2001-08-08 2003-02-13 Hallman Arlan Jay Cryogenic massage tube and compress
US6571564B2 (en) 2001-10-23 2003-06-03 Shashank Upadhye Timed container warmer and cooler
US20040092920A1 (en) 2001-12-20 2004-05-13 Eyal Rozenshpeer Cutting and removal of biologic tissue by pressurized propulsion of ice particles
CH695758A5 (en) 2002-03-05 2006-08-31 Tecpharma Licensing Ag Cooler for injection devices.
US8840608B2 (en) 2002-03-15 2014-09-23 The General Hospital Corporation Methods and devices for selective disruption of fatty tissue by controlled cooling
AU2003220311B2 (en) * 2002-03-15 2009-01-29 The General Hospital Corporation Methods and devices for selective disruption of fatty tissue by controlled cooling
US7211066B1 (en) * 2002-07-15 2007-05-01 Focal Cool, Llc Active surface exchange catheter and method
US6866662B2 (en) * 2002-07-23 2005-03-15 Biosense Webster, Inc. Ablation catheter having stabilizing array
AU2003270600B2 (en) * 2002-09-12 2008-08-14 Radiant Medical, Inc. System and method for determining and controlling core body temperature
US8361067B2 (en) 2002-09-30 2013-01-29 Relievant Medsystems, Inc. Methods of therapeutically heating a vertebral body to treat back pain
US7883490B2 (en) 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
US7118591B2 (en) 2003-04-17 2006-10-10 The University Of Chicago Heat transfer probe
US20040267338A1 (en) 2003-06-25 2004-12-30 Kent Harrison Targeted tissue cooling within a body
US7654997B2 (en) 2004-04-21 2010-02-02 Acclarent, Inc. Devices, systems and methods for diagnosing and treating sinusitus and other disorders of the ears, nose and/or throat
US20060036302A1 (en) 2004-05-28 2006-02-16 Kasza Kenneth E Methods of inducing protective hypothermia of organs
US20060199196A1 (en) 2004-11-05 2006-09-07 Invitrogen Corporation Compositions and methods for using radio frequency identifiers in biological sciences
US20060161232A1 (en) * 2005-01-18 2006-07-20 Kasza, Oras and Son to The University of Chicago Phase-change particulate ice slurry coolant medical delivery tubing and insertion devices
US8308681B2 (en) 2005-02-09 2012-11-13 Children's Medical Center Corporation Device for mixing and delivering fluids for tissue repair
US20060190066A1 (en) 2005-02-23 2006-08-24 Worthen William J System and method for bringing hypothermia rapidly onboard
US7713266B2 (en) 2005-05-20 2010-05-11 Myoscience, Inc. Subdermal cryogenic remodeling of muscles, nerves, connective tissue, and/or adipose tissue (fat)
CN101267784B (en) 2005-08-22 2011-06-15 基兰·P·默菲 Bone Augmentation Device
US7967763B2 (en) 2005-09-07 2011-06-28 Cabochon Aesthetics, Inc. Method for treating subcutaneous tissues
US7389653B2 (en) 2005-09-15 2008-06-24 The University Of Chicago Medical ice slurry production device
US20070093697A1 (en) 2005-10-21 2007-04-26 Theranova, Llc Method and apparatus for detection of right to left shunting in the cardiopulmonary vasculature
US7681411B2 (en) 2006-01-17 2010-03-23 Dilorenzo Thomas Ice making and dispensing method and apparatus with increased sanitation
US20080045880A1 (en) 2006-02-11 2008-02-21 Rune Kjeken Device and method for single-needle in vivo electroporation
US7854754B2 (en) 2006-02-22 2010-12-21 Zeltiq Aesthetics, Inc. Cooling device for removing heat from subcutaneous lipid-rich cells
US8147453B2 (en) 2006-03-13 2012-04-03 Applied Medical Resources Corporation Balloon trocar
KR101039758B1 (en) 2006-04-28 2011-06-09 젤티크 애스세틱스, 인코포레이티드. Cryoprotectants for use with therapeutic devices for improved cooling of subcutaneous lipid-rich cells
US20070270925A1 (en) 2006-05-17 2007-11-22 Juniper Medical, Inc. Method and apparatus for non-invasively removing heat from subcutaneous lipid-rich cells including a coolant having a phase transition temperature
JP2009539575A (en) * 2006-06-14 2009-11-19 ボエッジ メディカル， インコーポレイテッド Visualization apparatus and method for transseptal access
US20080077201A1 (en) 2006-09-26 2008-03-27 Juniper Medical, Inc. Cooling devices with flexible sensors
US9132031B2 (en) 2006-09-26 2015-09-15 Zeltiq Aesthetics, Inc. Cooling device having a plurality of controllable cooling elements to provide a predetermined cooling profile
US8192474B2 (en) 2006-09-26 2012-06-05 Zeltiq Aesthetics, Inc. Tissue treatment methods
WO2008055243A2 (en) 2006-10-31 2008-05-08 Zeltiq Aesthetics, Inc. Method and apparatus for cooling subcutaneous lipid-rich cells or tissue
US8382704B2 (en) 2006-12-29 2013-02-26 Medrad, Inc. Systems and methods of delivering a dilated slurry to a patient
US8057426B2 (en) 2007-01-03 2011-11-15 Medtronic Vascular, Inc. Devices and methods for injection of multiple-component therapies
US20080287839A1 (en) 2007-05-18 2008-11-20 Juniper Medical, Inc. Method of enhanced removal of heat from subcutaneous lipid-rich cells and treatment apparatus having an actuator
WO2008153789A1 (en) 2007-05-29 2008-12-18 Van Lewis Injector and thermal jacket for use with same
US20090018626A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. User interfaces for a system that removes heat from lipid-rich regions
US8523927B2 (en) 2007-07-13 2013-09-03 Zeltiq Aesthetics, Inc. System for treating lipid-rich regions
US20090018624A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. Limiting use of disposable system patient protection devices
US20090018625A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. Managing system temperature to remove heat from lipid-rich regions
US20090018627A1 (en) 2007-07-13 2009-01-15 Juniper Medical, Inc. Secure systems for removing heat from lipid-rich regions
US7740612B2 (en) 2007-07-27 2010-06-22 Milestone Scientific, Inc Self-administration injection system
EP4647051A2 (en) 2007-08-21 2025-11-12 Zeltiq Aesthetics, Inc. Monitoring the cooling of subcutaneous lipid-rich cells, such as the cooling of adipose tissue
JP2011502237A (en) 2007-10-19 2011-01-20 ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア System and method for generation of two-phase coolant and determination of its cooling capacity
US8298216B2 (en) 2007-11-14 2012-10-30 Myoscience, Inc. Pain management using cryogenic remodeling
US8128605B2 (en) 2007-12-24 2012-03-06 Mentor Worldwide Llc Syringe for use in medical applications
US8366759B2 (en) * 2007-12-28 2013-02-05 3M Innovative Properties Company Therapy device
WO2009089090A2 (en) 2008-01-03 2009-07-16 Vertos Medical, Inc. Thermally regulated hypodermic needles, methods of use, and kits
US20090234325A1 (en) * 2008-03-17 2009-09-17 Allan Rozenberg Methods and devices for non-invasive cerebral and systemic cooling
US8505315B2 (en) * 2008-04-15 2013-08-13 Uchicago Argonne, Llc Enhanced integrated operation blender based sterile medical ice slurry production device
US8535275B2 (en) 2008-06-26 2013-09-17 Bellanovus Development Company Llc Syringe-attached topical anesthetic dispenser
CN104720960B (en) 2008-08-07 2018-03-23 通用医疗公司 Method and apparatus for dermatology hypopigmentation
US20100036295A1 (en) 2008-08-08 2010-02-11 Palomar Medical Technologies, Inc. Method and apparatus for fractional deformation and treatment of cutaneous and subcutaneous tissue
EP2346428B1 (en) 2008-09-25 2019-11-06 Zeltiq Aesthetics, Inc. Treatment planning systems and methods for body contouring applications
US8518031B2 (en) 2008-10-31 2013-08-27 The Invention Science Fund I, Llc Systems, devices and methods for making or administering frozen particles
JP5713406B2 (en) 2008-12-02 2015-05-07 クール セラピューティクス， インコーポレイテッド System for delivery of respiratory gases with fine ice particles
US8603073B2 (en) 2008-12-17 2013-12-10 Zeltiq Aesthetics, Inc. Systems and methods with interrupt/resume capabilities for treating subcutaneous lipid-rich cells
CA2749978A1 (en) 2009-01-20 2010-07-29 F. Hoffmann-La Roche Ag Cryogenic container
KR101832498B1 (en) 2009-02-06 2018-02-26 테크레스 에스.피.에이. Mixer for biphasic compounds
US8608696B1 (en) 2009-02-24 2013-12-17 North Carolina State University Rapid fluid cooling devices and methods for cooling fluids
US20100249753A1 (en) 2009-02-25 2010-09-30 Gaisser David M Vented syringe system and method for the containment, mixing and ejection of wetted particulate material
EP2421459A1 (en) 2009-04-22 2012-02-29 Nuvue Therapeutics, Inc. Fluid flowing device and method for tissue diagnosis or therapy
US7963939B2 (en) 2009-04-24 2011-06-21 Thomas Chun Syringe having extended blending path
KR101759116B1 (en) 2009-04-30 2017-07-18 젤티크 애스세틱스, 인코포레이티드. Device, system and method of removing heat from subcutaneous lipid-rich cells
US20140200511A1 (en) 2009-10-30 2014-07-17 Searete Llc Systems, devices, and methods for making or administering frozen particles
US20110300079A1 (en) 2010-01-21 2011-12-08 Zeltiq Aesthetics, Inc. Compositions for use with a system for improved cooling of subcutaneous lipid-rich tissue
EP2528560A1 (en) 2010-01-25 2012-12-05 Zeltiq Aesthetics, Inc. Home-use applicators for non-invasively removing heat from subcutaneous lipid-rich cells via phase change coolants, and associated devices, systems and methods
US9033965B2 (en) 2010-02-01 2015-05-19 Boston Scientific Scimed, Inc. Nested balloon cryotherapy
WO2011100692A1 (en) * 2010-02-15 2011-08-18 The General Hospital Corporation Methods and devices for selective disruption of visceral fat by controlled cooling
US8950207B2 (en) 2010-03-30 2015-02-10 Hyper Wear, Inc. Device for stimulating adaptive thermogenesis in brown adipose tissue
AU2011264935A1 (en) 2010-06-08 2013-01-24 NanoICE, Inc. Ultra-small ice, uses thereof and apparatus for production
US8676338B2 (en) 2010-07-20 2014-03-18 Zeltiq Aesthetics, Inc. Combined modality treatment systems, methods and apparatus for body contouring applications
JP5934211B2 (en) 2010-08-19 2016-06-15 シネロン メディカル リミテッド Electromagnetic energy applicator for personal cosmetic skin treatment
US8974451B2 (en) 2010-10-25 2015-03-10 Boston Scientific Scimed, Inc. Renal nerve ablation using conductive fluid jet and RF energy
US10722395B2 (en) 2011-01-25 2020-07-28 Zeltiq Aesthetics, Inc. Devices, application systems and methods with localized heat flux zones for removing heat from subcutaneous lipid-rich cells
CA2825624C (en) 2011-01-27 2020-01-14 Osa Holdings, Inc. Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
US20120203312A1 (en) * 2011-02-05 2012-08-09 Rachel Elizabeth Batzer Surgical cooling device
CA2832593A1 (en) * 2011-04-08 2012-07-18 Joseph D. Brannan Flexible microwave catheters for natural or artificial lumens
US8690934B2 (en) 2011-05-09 2014-04-08 The Invention Science Fund I, Llc Method, device and system for modulating an activity of brown adipose tissue in a vertebrate subject
WO2013021380A1 (en) 2011-08-09 2013-02-14 Syneron Beauty Ltd. A method and apparatus for cosmetic skin care
US9056185B2 (en) 2011-08-24 2015-06-16 Ablative Solutions, Inc. Expandable catheter system for fluid injection into and deep to the wall of a blood vessel
US20130053792A1 (en) 2011-08-24 2013-02-28 Ablative Solutions, Inc. Expandable catheter system for vessel wall injection and muscle and nerve fiber ablation
US9414959B2 (en) 2011-09-05 2016-08-16 Qool Therapeutics, Inc. Gastric, cutaneous, or peritoneal delivery of frozen mist to induce therapeutic hyperthermia
CN109602489A (en) 2011-11-16 2019-04-12 通用医疗公司 Method and device for cryogenic treatment of skin tissue
CN107874896A (en) 2011-11-16 2018-04-06 通用医疗公司 Method and apparatus for low-temperature treatment skin histology
US9458505B2 (en) 2011-12-20 2016-10-04 The Cleveland Clinic Foundation Diagnosis of cowden and cowden-like syndrome by detection of decreased killin expression
ES2421545B1 (en) 2012-02-01 2014-06-25 Universitat Polit�Cnica De Catalunya BODY CEMENT DOSAGE AND INJECTION DEVICE
DE202012002278U1 (en) 2012-03-08 2012-06-26 Friedemann Lotsch Device for cryolipolysis
IL219477A0 (en) 2012-04-30 2012-07-31 Berger Thermal Res Ltd A method for coupling between catheter tip and tissue by icing their interface and apparatus therefor
EP2668988B1 (en) 2012-05-30 2018-11-07 ARKRAY, Inc. Channel bubble reduction device, channel bubble reduction program, channel bubble reduction method, liquid provision device and chromatography device
WO2013181667A1 (en) 2012-06-01 2013-12-05 Cibiem, Inc. Percutaneous methods and devices for carotid body ablation
CA2878458C (en) 2012-07-06 2020-08-18 The General Hospital Corporation Method and apparatus for dermatological treatment
WO2014046552A1 (en) 2012-09-20 2014-03-27 Graham Brewster Ice slurry delivery system and components thereof
US9301795B2 (en) 2012-10-29 2016-04-05 Ablative Solutions, Inc. Transvascular catheter for extravascular delivery
WO2014071161A1 (en) 2012-11-05 2014-05-08 Relievant Medsystems, Inc. System and methods for creating curved paths through bone and modulating nerves within the bone
US9844460B2 (en) 2013-03-14 2017-12-19 Zeltiq Aesthetics, Inc. Treatment systems with fluid mixing systems and fluid-cooled applicators and methods of using the same
US9545523B2 (en) 2013-03-14 2017-01-17 Zeltiq Aesthetics, Inc. Multi-modality treatment systems, methods and apparatus for altering subcutaneous lipid-rich tissue
CN103110473A (en) 2013-03-17 2013-05-22 广州市绿乔生物科技有限公司 Cold-dispelling and dehumidification healthcare bag and application method thereof
WO2014168832A1 (en) 2013-04-08 2014-10-16 Farhan Taghizadeh System and method for providing treatment feedback for a thermal treatment device
WO2014197625A1 (en) 2013-06-05 2014-12-11 Metavention, Inc. Modulation of targeted nerve fibers
US9456861B2 (en) 2013-06-24 2016-10-04 Nordson Corporation Dispensing assembly having mixing and plunging assembly, and related methods
US10406021B2 (en) 2013-08-05 2019-09-10 Yue Wu Method and system for producing and delivering airless medical ice slurry to induce hypothermia
US9949652B2 (en) 2013-10-25 2018-04-24 Ablative Solutions, Inc. Apparatus for effective ablation and nerve sensing associated with denervation
ES2974899T3 (en) 2014-01-31 2024-07-02 Zeltiq Aesthetics Inc Compositions and treatment systems for enhanced cooling of lipid-rich tissue
EP3119356B1 (en) 2014-03-21 2019-03-20 The University of Western Ontario Mammalian head cooling system
US9550028B2 (en) 2014-05-06 2017-01-24 Biomet Biologics, LLC. Single step desiccating bead-in-syringe concentrating device
US10568759B2 (en) 2014-08-19 2020-02-25 Zeltiq Aesthetics, Inc. Treatment systems, small volume applicators, and methods for treating submental tissue
US10646666B2 (en) 2014-08-27 2020-05-12 Tva Medical, Inc. Cryolipolysis devices and methods therefor
AU2015308794A1 (en) 2014-08-28 2017-03-02 The General Hospital Corporation Injectable slurries and methods of manufacturing and using the same
US20160081974A1 (en) 2014-09-18 2016-03-24 Research & Business Foundation Sungkyunkwan University Composition for preventing or treating edema containing flavonoid compound
US20160089550A1 (en) 2014-09-25 2016-03-31 Zeltiq Aesthetics, Inc. Treatment systems, methods, and apparatuses for altering the appearance of skin
EP3200736B8 (en) 2014-10-01 2020-06-17 CryOSA, Inc. Apparatus for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
WO2016054165A1 (en) 2014-10-01 2016-04-07 Novocor Medical Systems, Inc. Fluid cooling devices, systems and methods for cooling fluids
DE102015117727A1 (en) 2014-10-20 2016-04-21 Dspace Digital Signal Processing And Control Engineering Gmbh Protection of software models
CN105640706A (en) 2014-11-14 2016-06-08 湖北文理学院 Cold compress adhesive bandage
WO2016090175A1 (en) 2014-12-03 2016-06-09 Metavention, Inc. Systems and methods for modulating nerves or other tissue
US10092738B2 (en) 2014-12-29 2018-10-09 Ethicon Llc Methods and devices for inhibiting nerves when activating brown adipose tissue
EP3261593B1 (en) * 2015-02-23 2021-11-03 Qool Therapeutics, Inc. Systems and methods for endotracheal delivery of frozen particles
EP3288626B8 (en) 2015-04-27 2025-12-10 Tulavi Therapeutics, Inc. Substances and compositions for use in blocking nerve regeneration
ES2888824T3 (en) 2015-10-05 2022-01-07 C Change Surgical Llc Use of sterile cuff in the production of surgical crushed ice
ES2892598T3 (en) 2015-10-19 2022-02-04 Zeltiq Aesthetics Inc Vascular treatment methods to cool vascular structures
EP3402550B1 (en) 2016-01-13 2023-12-13 The General Hospital Corporation DBA Massachusetts Methods for removing exogenous particles from the skin of a patient
WO2017147367A1 (en) 2016-02-26 2017-08-31 The General Hospital Corporation Medical ice slurry production and delivery systems and methods
CA3023821A1 (en) 2016-05-10 2017-11-16 Zeltiq Aesthetics, Inc. Skin freezing systems for treating acne and skin conditions
US11382790B2 (en) 2016-05-10 2022-07-12 Zeltiq Aesthetics, Inc. Skin freezing systems for treating acne and skin conditions
US20180008444A1 (en) * 2016-07-11 2018-01-11 Cook Medical Technologies Llc Multi-stage balloon catheter, and method of operating same in a curved passageway
BR112019008954A2 (en) 2016-11-02 2019-07-09 J P Velis Christopher devices and methods for generating slurry
US11324673B2 (en) 2016-11-18 2022-05-10 Miraki Innovation Think Tank Llc Cosmetic appearance of skin
WO2018160797A1 (en) 2017-03-01 2018-09-07 Arctic Fox Biomedical, Inc. Cryotherapies
CA3059294A1 (en) 2017-04-05 2018-10-11 Miraki Innovation Think Tank Llc Point of delivery cold slurry generation
US10500342B2 (en) 2017-08-21 2019-12-10 Miraki Innovation Think Tank Llc Cold slurry syringe
MX2019012352A (en) 2018-10-15 2020-08-20 Avent Inc Compositions, systems, kits, and methods for neural ablation.
GB2578830B (en) 2018-10-15 2021-02-10 Avent Inc Systems and methods for delivering a polymeric material to a treatment site during a radio frequency ablation procedure

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