SG11201810031RA - Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods - Google Patents
Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methodsInfo
- Publication number
- SG11201810031RA SG11201810031RA SG11201810031RA SG11201810031RA SG11201810031RA SG 11201810031R A SG11201810031R A SG 11201810031RA SG 11201810031R A SG11201810031R A SG 11201810031RA SG 11201810031R A SG11201810031R A SG 11201810031RA SG 11201810031R A SG11201810031R A SG 11201810031RA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- aldehyde
- lamon
- skokie
- avenue
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 4
- 108010074122 Ferredoxins Proteins 0.000 title abstract 3
- 108090000854 Oxidoreductases Proteins 0.000 title abstract 3
- 102000004316 Oxidoreductases Human genes 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 244000005700 microbiome Species 0.000 title abstract 2
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 title 1
- 102000007698 Alcohol dehydrogenase Human genes 0.000 abstract 3
- 241000894006 Bacteria Species 0.000 abstract 3
- 150000001299 aldehydes Chemical class 0.000 abstract 3
- ROWKJAVDOGWPAT-UHFFFAOYSA-N Acetoin Chemical compound CC(O)C(C)=O ROWKJAVDOGWPAT-UHFFFAOYSA-N 0.000 abstract 2
- 108010021809 Alcohol dehydrogenase Proteins 0.000 abstract 2
- 102000005369 Aldehyde Dehydrogenase Human genes 0.000 abstract 2
- 102000004190 Enzymes Human genes 0.000 abstract 2
- 108090000790 Enzymes Proteins 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 230000003247 decreasing effect Effects 0.000 abstract 2
- 229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 abstract 2
- BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 abstract 2
- NMDWGEGFJUBKLB-UHFFFAOYSA-M 2-acetyllactate Chemical compound CC(=O)C(C)(O)C([O-])=O NMDWGEGFJUBKLB-UHFFFAOYSA-M 0.000 abstract 1
- 108020002663 Aldehyde Dehydrogenase Proteins 0.000 abstract 1
- JVTAAEKCZFNVCJ-UHFFFAOYSA-M Lactate Chemical compound CC(O)C([O-])=O JVTAAEKCZFNVCJ-UHFFFAOYSA-M 0.000 abstract 1
- XJLXINKUBYWONI-NNYOXOHSSA-O NADP(+) Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](OP(O)(O)=O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 XJLXINKUBYWONI-NNYOXOHSSA-O 0.000 abstract 1
- 101710181816 Pyruvate-formate-lyase deactivase Proteins 0.000 abstract 1
- LIPOUNRJVLNBCD-UHFFFAOYSA-N acetyl dihydrogen phosphate Chemical compound CC(=O)OP(O)(O)=O LIPOUNRJVLNBCD-UHFFFAOYSA-N 0.000 abstract 1
- 230000001588 bifunctional effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- OWBTYPJTUOEWEK-UHFFFAOYSA-N butane-2,3-diol Chemical compound CC(O)C(C)O OWBTYPJTUOEWEK-UHFFFAOYSA-N 0.000 abstract 1
- 238000012258 culturing Methods 0.000 abstract 1
- GFAZHVHNLUBROE-UHFFFAOYSA-N hydroxymethyl propionaldehyde Natural products CCC(=O)CO GFAZHVHNLUBROE-UHFFFAOYSA-N 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
- C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/065—Ethanol, i.e. non-beverage with microorganisms other than yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/01—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
- C12Y102/0101—Acetaldehyde dehydrogenase (acetylating) (1.2.1.10)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y102/00—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
- C12Y102/07—Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with an iron-sulfur protein as acceptor (1.2.7)
- C12Y102/07005—Aldehyde ferredoxin oxidoreductase (1.2.7.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
- C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
- C12Y101/01001—Alcohol dehydrogenase (1.1.1.1)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Oil, Petroleum & Natural Gas (AREA)
Abstract
NADP)H AD(P). Ethanol NAD lactate .66H' ATP Synthas ADP 4. Pi V pyruvate CO 2 Acetolactate hr's a Acetoin 2,3BDHrAD(P)11 NADiPj• 2,3-Butanediol CoFeSP-[Chli 3 Acetyl-P ADP NAD(P)- Acetate Acetaldehyde Ald, AdhE NAD(P)H NADH N [CO] HADPH Fd Anabolism CO/ 4 1 4 e Fc‘,. x A N „ Acety-CoA Pf or Pyruvate NAD' 2NA PH NADH FIG. 1 A155 1-1 71- GC GC N O 1-1 C (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 23 November 2017 (23.11.2017) WIPO I PCT o 1E1 olo VIII olommiolons H moimmio oimIE (10) International Publication Number WO 2017/200884 Al (51) International Patent Classification: C12N 1/20 (2006.01) Cl 2N 9/04 (2006.01) C12P 7/06 (2006.01) Cl 2N 9/02 (2006.01) (21) International Application Number: PCT/US2017/032564 (22) International Filing Date: 12 May 2017 (12.05.2017) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 62/336,639 14 May 2016 (14.05.2016) US (71) Applicant: LANZATECH, INC. [US/US]; 8045 Lamon Avenue, Suite 400, Skokie, Illinois 60077 (US). (72) Inventors: LIEW, Fungmin; 8045 Lamon Avenue, Suite 400, Skokie, Illinois 60077 (US). KOEPKE, Michael; 8045 Lamon Avenue, Suite 400, Skokie, Illinois 60077 (US). (74) Agent: SCHOEN, Andrea E.; 8045 Lamon Avenue, Suite 400, Skokie, Illinois 60077 (US). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, (54) Title: MICROORGANISM WITH MODIFIED ALDEHYDE:FERREDOXIN OXIDOREDUCTASE ACTIVITY AND RELAT- ED METHODS (57) : The invention provides a non-naturally occurring bacterium having decreased or eliminated activity of an enzyme that catalyzes the reaction defined by EC 1.2.7.5, such as aldehyde:ferredoxin oxidoreductase (AOR). Optionally, the bacterium also has decreased or eliminated activity of an enzyme that catalyzes the reaction defined by EC 1.2.1.10 and/or EC 1.1.1.1, such as aldehyde dehydrogenase, alcohol dehydrogenase, or bifunctional aldehyde/alcohol dehydrogenase. The invention further provides methods of producing products by culturing the bacterium in the presence of a gaseous substrate containing one or more of CO, CO2, and H2. [Continued on next page] WO 2017/200884 Al MIDEDIMOMMIDIRMEM0010101EIHMINVOIMIE TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) before the expiration of the time limit for amending the claims and to be republished in the event of receipt of amendments (Rule 48.2(h))
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662336639P | 2016-05-14 | 2016-05-14 | |
| PCT/US2017/032564 WO2017200884A1 (en) | 2016-05-14 | 2017-05-12 | Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201810031RA true SG11201810031RA (en) | 2018-12-28 |
Family
ID=60295016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201810031RA SG11201810031RA (en) | 2016-05-14 | 2017-05-12 | Microorganism with modified aldehyde:ferredoxin oxidoreductase activity and related methods |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10294498B2 (en) |
| EP (1) | EP3464559A4 (en) |
| JP (2) | JP7502029B2 (en) |
| KR (2) | KR102514023B1 (en) |
| CN (1) | CN109477063A (en) |
| CA (1) | CA3024114C (en) |
| EA (1) | EA201892627A1 (en) |
| SG (1) | SG11201810031RA (en) |
| WO (1) | WO2017200884A1 (en) |
| ZA (1) | ZA201807617B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7502029B2 (en) * | 2016-05-14 | 2024-06-18 | ランザテク，インコーポレイテッド | Modified aldehyde:microorganisms with ferredoxin oxidoreductase activity and related methods |
| US11976314B2 (en) * | 2017-08-29 | 2024-05-07 | Gwangju Institute Of Science And Technology | Method for converting non-ethanol producing, acetogenic strain to ethanol-producing strain and method for producing ethanol from same ethanol-producing strain by using carbon monoxide |
| CN109929862B (en) * | 2019-03-14 | 2022-09-16 | 云南农业大学 | A method for screening cellulase genes for cloning from ruminant rumen metatranscriptomic data |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5593886A (en) | 1992-10-30 | 1997-01-14 | Gaddy; James L. | Clostridium stain which produces acetic acid from waste gases |
| UA72220C2 (en) | 1998-09-08 | 2005-02-15 | Байоенджініерінг Рісорсиз, Інк. | Water-immiscible mixture solvent/cosolvent for extracting acetic acid, a method for producing acetic acid (variants), a method for anaerobic microbial fermentation for obtaining acetic acid (variants), modified solvent and a method for obtaining thereof |
| NZ546496A (en) | 2006-04-07 | 2008-09-26 | Lanzatech New Zealand Ltd | Gas treatment process |
| US7704723B2 (en) | 2006-08-31 | 2010-04-27 | The Board Of Regents For Oklahoma State University | Isolation and characterization of novel clostridial species |
| NZ553984A (en) | 2007-03-19 | 2009-07-31 | Lanzatech New Zealand Ltd | Alcohol production process |
| KR101375029B1 (en) | 2007-11-13 | 2014-03-14 | 란자테크 뉴질랜드 리미티드 | Novel bacteria and methods of use thereof |
| CA2727549C (en) | 2008-06-09 | 2014-08-26 | Lanzatech New Zealand Limited | Production of butanediol by anaerobic microbial fermentation |
| US8039239B2 (en) | 2008-12-16 | 2011-10-18 | Coskata, Inc. | Recombinant microorganisms having modified production of alcohols and acids |
| EP2545178A4 (en) | 2010-03-10 | 2014-06-11 | Lanzatech New Zealand Ltd | Acid production by fermentation |
| US20110262954A1 (en) * | 2010-03-18 | 2011-10-27 | Universitat Regensburg | Shuttle vector based transformation system for pyrococcus furiosus |
| EP2606138A2 (en) | 2010-08-19 | 2013-06-26 | Lanzatech New Zealand Limited | A process for producing chemicals using microbial fermentation of substrates comprising carbon monoxide |
| US20130157322A1 (en) | 2010-08-26 | 2013-06-20 | Lanzatech New Zealand Limited | Process for producing ethanol and ethylene via fermentation |
| US20110236941A1 (en) | 2010-10-22 | 2011-09-29 | Lanzatech New Zealand Limited | Recombinant microorganism and methods of production thereof |
| ES2702621T3 (en) | 2011-02-25 | 2019-03-04 | Lanzatech New Zealand Ltd | Recombinant microorganisms and their uses |
| CN103582703A (en) * | 2011-03-31 | 2014-02-12 | 新西兰郎泽科技公司 | A fermentation process for controlling butanediol production |
| PL2753700T3 (en) | 2011-09-08 | 2020-07-27 | Lanzatech New Zealand Limited | A fermentation process |
| WO2013180581A1 (en) | 2012-05-30 | 2013-12-05 | Lanzatech New Zealand Limited | Recombinant microorganisms and uses therefor |
| US20130323820A1 (en) | 2012-06-01 | 2013-12-05 | Lanzatech New Zealand Limited | Recombinant microorganisms and uses therefor |
| WO2013185123A1 (en) | 2012-06-08 | 2013-12-12 | Lanzatech New Zealand Limited | Recombinant microorganisms and uses therefor |
| US9347076B2 (en) | 2012-06-21 | 2016-05-24 | Lanzatech New Zealand Limited | Recombinant microorganisms that make biodiesel |
| CN105051179B (en) | 2012-08-28 | 2018-06-15 | 朗泽科技新西兰有限公司 | Recombinant microorganism and its purposes |
| EP4424833A2 (en) * | 2013-03-15 | 2024-09-04 | LanzaTech NZ, Inc. | A system and method for controlling metabolite production in a microbial fermentation |
| EP3004362A4 (en) | 2013-06-05 | 2017-01-11 | Lanzatech New Zealand Limited | Recombinant microorganisms exhibiting increased flux through a fermentation pathway |
| US20150275238A1 (en) * | 2014-03-28 | 2015-10-01 | University Of Georgia Research Foundation, Inc. | Genetically engineered microbes and methods for converting organic acids to alcohols |
| CN107002012B (en) | 2014-10-22 | 2019-04-26 | 朗泽科技新西兰有限公司 | Multistage bioreactor process |
| BR122023023155A2 (en) | 2015-05-27 | 2024-03-05 | Lanzatech Nz, Inc. | GENETICALLY MODIFIED C1-FIXING BACTERIA CAPABLE OF PRODUCING AT LEAST ONE PRODUCT DERIVED FROM CHORISMATE, AND METHOD OF MANUFACTURING A FERMENTATION PRODUCT |
| CN113322220A (en) | 2015-10-13 | 2021-08-31 | 朗泽科技新西兰有限公司 | Genetically engineered bacterium containing energy-producing fermentation way |
| JP7502029B2 (en) * | 2016-05-14 | 2024-06-18 | ランザテク，インコーポレイテッド | Modified aldehyde:microorganisms with ferredoxin oxidoreductase activity and related methods |
-
2017
- 2017-05-12 JP JP2019512182A patent/JP7502029B2/en active Active
- 2017-05-12 WO PCT/US2017/032564 patent/WO2017200884A1/en unknown
- 2017-05-12 EP EP17799922.4A patent/EP3464559A4/en active Pending
- 2017-05-12 KR KR1020187035923A patent/KR102514023B1/en active Active
- 2017-05-12 SG SG11201810031RA patent/SG11201810031RA/en unknown
- 2017-05-12 US US15/594,252 patent/US10294498B2/en active Active
- 2017-05-12 EA EA201892627A patent/EA201892627A1/en unknown
- 2017-05-12 CN CN201780029930.1A patent/CN109477063A/en active Pending
- 2017-05-12 CA CA3024114A patent/CA3024114C/en active Active
- 2017-05-12 KR KR1020237009707A patent/KR20230044031A/en not_active Ceased
-
2018
- 2018-11-13 ZA ZA2018/07617A patent/ZA201807617B/en unknown
-
2022
- 2022-07-19 JP JP2022115092A patent/JP2022163046A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US10294498B2 (en) | 2019-05-21 |
| CA3024114C (en) | 2020-02-04 |
| ZA201807617B (en) | 2021-04-28 |
| KR102514023B1 (en) | 2023-03-23 |
| EP3464559A4 (en) | 2020-02-12 |
| EA201892627A1 (en) | 2019-04-30 |
| KR20190017790A (en) | 2019-02-20 |
| JP7502029B2 (en) | 2024-06-18 |
| CA3024114A1 (en) | 2017-11-23 |
| CN109477063A (en) | 2019-03-15 |
| JP2022163046A (en) | 2022-10-25 |
| JP2019514441A (en) | 2019-06-06 |
| WO2017200884A1 (en) | 2017-11-23 |
| EP3464559A1 (en) | 2019-04-10 |
| KR20230044031A (en) | 2023-03-31 |
| US20170327849A1 (en) | 2017-11-16 |
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