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SG11201708622UA - 3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors - Google Patents

3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors

Info

Publication number
SG11201708622UA
SG11201708622UA SG11201708622UA SG11201708622UA SG11201708622UA SG 11201708622U A SG11201708622U A SG 11201708622UA SG 11201708622U A SG11201708622U A SG 11201708622UA SG 11201708622U A SG11201708622U A SG 11201708622UA SG 11201708622U A SG11201708622U A SG 11201708622UA
Authority
SG
Singapore
Prior art keywords
amido
bicyclic
aryl
hdac inhibitors
hydroxamic acids
Prior art date
Application number
SG11201708622UA
Inventor
Xiaozhang Zheng
Pui Yee Ng
Bingsong Han
Jennifer R Thomason
Mary-Margaret Zablocki
Cuixian Liu
Heather Davis
Aleksandra Rudnitskaya
Jr David Lancia
David S Millan
Matthew W Martin
Original Assignee
Forma Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Forma Therapeutics Inc filed Critical Forma Therapeutics Inc
Publication of SG11201708622UA publication Critical patent/SG11201708622UA/en

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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    • C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
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SG11201708622UA 2015-02-02 2016-02-02 3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors SG11201708622UA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562110716P 2015-02-02 2015-02-02
US201562205438P 2015-08-14 2015-08-14
PCT/US2016/016200 WO2016126724A1 (en) 2015-02-02 2016-02-02 3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors

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SG11201708622UA true SG11201708622UA (en) 2017-11-29

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SG11201708622UA SG11201708622UA (en) 2015-02-02 2016-02-02 3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors
SG11201706146UA SG11201706146UA (en) 2015-02-02 2016-02-02 3-alkyl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors
SG10202100916PA SG10202100916PA (en) 2015-02-02 2016-02-02 3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors
SG10202100915RA SG10202100915RA (en) 2015-02-02 2016-02-02 3-alkyl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors

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SG11201706146UA SG11201706146UA (en) 2015-02-02 2016-02-02 3-alkyl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors
SG10202100916PA SG10202100916PA (en) 2015-02-02 2016-02-02 3-aryl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors
SG10202100915RA SG10202100915RA (en) 2015-02-02 2016-02-02 3-alkyl-4-amido-bicyclic [4,5,0] hydroxamic acids as hdac inhibitors

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US (32) US10239845B2 (en)
EP (3) EP3253747B1 (en)
JP (1) JP6668362B2 (en)
KR (1) KR102633628B1 (en)
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