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SG11201706727XA - Methods, compositions, and kits for treatment of cancer - Google Patents

Methods, compositions, and kits for treatment of cancer

Info

Publication number
SG11201706727XA
SG11201706727XA SG11201706727XA SG11201706727XA SG11201706727XA SG 11201706727X A SG11201706727X A SG 11201706727XA SG 11201706727X A SG11201706727X A SG 11201706727XA SG 11201706727X A SG11201706727X A SG 11201706727XA SG 11201706727X A SG11201706727X A SG 11201706727XA
Authority
SG
Singapore
Prior art keywords
kits
cancer
compositions
treatment
methods
Prior art date
Application number
SG11201706727XA
Inventor
Jocelyn Holash
Stephen Lau
Original Assignee
Bioclin Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioclin Therapeutics Inc filed Critical Bioclin Therapeutics Inc
Publication of SG11201706727XA publication Critical patent/SG11201706727XA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11201706727XA 2015-02-19 2016-02-19 Methods, compositions, and kits for treatment of cancer SG11201706727XA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562118350P 2015-02-19 2015-02-19
US201562150235P 2015-04-20 2015-04-20
PCT/US2016/018634 WO2016134234A1 (en) 2015-02-19 2016-02-19 Methods, compositions, and kits for treatment of cancer

Publications (1)

Publication Number Publication Date
SG11201706727XA true SG11201706727XA (en) 2017-09-28

Family

ID=56689191

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201706727XA SG11201706727XA (en) 2015-02-19 2016-02-19 Methods, compositions, and kits for treatment of cancer

Country Status (12)

Country Link
US (1) US20160243228A1 (en)
EP (1) EP3258966A4 (en)
JP (2) JP6774421B2 (en)
KR (1) KR20170137717A (en)
CN (1) CN107635583A (en)
AU (2) AU2016219917B2 (en)
BR (1) BR112017017700A2 (en)
CA (1) CA2976638A1 (en)
IL (1) IL253979B (en)
MX (1) MX2017010595A (en)
SG (1) SG11201706727XA (en)
WO (1) WO2016134234A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104788564A (en) 2009-03-25 2015-07-22 健泰科生物技术公司 Anti-FGFR3 antibodies and methods using same
GB201007286D0 (en) 2010-04-30 2010-06-16 Astex Therapeutics Ltd New compounds
GB201209613D0 (en) 2012-05-30 2012-07-11 Astex Therapeutics Ltd New compounds
LT3122358T (en) 2014-03-26 2021-04-12 Astex Therapeutics Ltd. Combinations of fgfr- and cmet-inhibitors for the treatment of cancer
JO3512B1 (en) 2014-03-26 2020-07-05 Astex Therapeutics Ltd Quinoxaline derivatives useful as fgfr kinase modulators
BR112016022062B1 (en) 2014-03-26 2023-04-11 Astex Therapeutics Limited COMBINATION, PHARMACEUTICAL COMPOSITION, USE OF A COMBINATION OR A PHARMACEUTICAL COMPOSITION, AND, PHARMACEUTICAL PRODUCT
JOP20200201A1 (en) 2015-02-10 2017-06-16 Astex Therapeutics Ltd Pharmaceutical compositions comprising n-(3,5-dimethoxyphenyl)-n'-(1-methylethyl)-n-[3-(1-methyl-1h-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine
US10478494B2 (en) * 2015-04-03 2019-11-19 Astex Therapeutics Ltd FGFR/PD-1 combination therapy for the treatment of cancer
KR102691777B1 (en) 2015-09-23 2024-08-02 얀센 파마슈티카 엔브이 Non-heteroaryl substituted 1,4-benzodiazepines and their use for the treatment of cancer
BR112018005637B1 (en) 2015-09-23 2023-11-28 Janssen Pharmaceutica Nv COMPOUNDS DERIVED FROM QUINOXALINE, QUINOLINE AND QUINAZOLINONE, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM, AND USE OF SAID COMPOUNDS
JP2020506945A (en) * 2017-02-06 2020-03-05 レーニア セラピューティクス インコーポレイテッド Methods, compositions and kits for treating cancer
CN108440673B (en) * 2018-04-08 2021-08-17 海南医学院 Fc fusion protein PD1/FGFR1 and its application
US20200277387A1 (en) * 2019-03-01 2020-09-03 Rainier Therapeutics, Inc. Methods and compositions for treating cancer
JP2023514795A (en) * 2019-06-03 2023-04-11 フュージョン ファーマシューティカルズ インコーポレイテッド Methods and compositions for treating cancer
CN114466662A (en) * 2019-09-26 2022-05-10 詹森药业有限公司 Use of FGFR inhibitors in cancers with genetically altered FGFR to enhance patient response to immune checkpoint inhibitors in a sequential therapy setting
EP4200019A1 (en) 2020-08-21 2023-06-28 Genzyme Corporation Fgfr3 antibodies and methods of use
EP4209216A4 (en) * 2020-10-28 2024-10-02 Eisai R&D Management Co., Ltd. PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF TUMORS
US20240247069A1 (en) 2023-01-13 2024-07-25 Regeneron Pharmaceuticals, Inc. Fgfr3 binding molecules and methods of use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI381848B (en) * 2008-10-20 2013-01-11 Imclone Llc Anti-fibroblast growth factor receptor-3 (fgfr-3) antibodies and pharmaceutical composition comprising the same
CN104788564A (en) * 2009-03-25 2015-07-22 健泰科生物技术公司 Anti-FGFR3 antibodies and methods using same
WO2012088266A2 (en) * 2010-12-22 2012-06-28 Incyte Corporation Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
UY34887A (en) * 2012-07-02 2013-12-31 Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware OPTIMIZATION OF ANTIBODIES THAT FIX THE LYMPHOCYTE ACTIVATION GEN 3 (LAG-3) AND ITS USES
US20140030259A1 (en) * 2012-07-27 2014-01-30 Genentech, Inc. Methods of treating fgfr3 related conditions
CN105492025A (en) * 2013-07-16 2016-04-13 豪夫迈·罗氏有限公司 Methods of treating cancer using pd-1 axis binding antagonists and tigit inhibitors

Also Published As

Publication number Publication date
MX2017010595A (en) 2018-11-12
AU2022200196B2 (en) 2025-04-10
AU2022200196A1 (en) 2022-02-10
AU2016219917B2 (en) 2021-12-16
EP3258966A1 (en) 2017-12-27
JP2021020909A (en) 2021-02-18
JP6774421B2 (en) 2020-10-21
CA2976638A1 (en) 2016-08-25
IL253979A0 (en) 2017-10-31
AU2016219917A1 (en) 2017-09-07
BR112017017700A2 (en) 2018-07-31
IL253979B (en) 2021-06-30
NZ735243A (en) 2024-11-29
EP3258966A4 (en) 2018-07-25
CN107635583A (en) 2018-01-26
JP2018507220A (en) 2018-03-15
JP7122357B2 (en) 2022-08-19
WO2016134234A1 (en) 2016-08-25
US20160243228A1 (en) 2016-08-25
KR20170137717A (en) 2017-12-13

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