SG11201705964YA - Levodopa and carbidopa intestinal gel and methods of use - Google Patents
Levodopa and carbidopa intestinal gel and methods of useInfo
- Publication number
- SG11201705964YA SG11201705964YA SG11201705964YA SG11201705964YA SG11201705964YA SG 11201705964Y A SG11201705964Y A SG 11201705964YA SG 11201705964Y A SG11201705964Y A SG 11201705964YA SG 11201705964Y A SG11201705964Y A SG 11201705964YA SG 11201705964Y A SG11201705964Y A SG 11201705964YA
- Authority
- SG
- Singapore
- Prior art keywords
- levodopa
- methods
- intestinal gel
- carbidopa intestinal
- carbidopa
- Prior art date
Links
- IVTMXOXVAHXCHI-YXLMWLKOSA-N (2s)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid;(2s)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C(O)=C1.NN[C@@](C(O)=O)(C)CC1=CC=C(O)C(O)=C1 IVTMXOXVAHXCHI-YXLMWLKOSA-N 0.000 title 1
- 230000000968 intestinal effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dispersion Chemistry (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Psychology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562105565P | 2015-01-20 | 2015-01-20 | |
US201562272922P | 2015-12-30 | 2015-12-30 | |
PCT/US2016/014005 WO2016118556A1 (fr) | 2015-01-20 | 2016-01-20 | Gel intestinal de lévodopa et de carbidona et procédés d'utilisation |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201705964YA true SG11201705964YA (en) | 2017-08-30 |
Family
ID=55410198
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201705964YA SG11201705964YA (en) | 2015-01-20 | 2016-01-20 | Levodopa and carbidopa intestinal gel and methods of use |
Country Status (16)
Country | Link |
---|---|
US (3) | US10117843B2 (fr) |
EP (2) | EP4470611A3 (fr) |
JP (4) | JP2018503686A (fr) |
KR (1) | KR20170103967A (fr) |
CN (2) | CN116036064A (fr) |
AU (1) | AU2016209420B2 (fr) |
BR (1) | BR112017015613B1 (fr) |
CA (1) | CA2974203A1 (fr) |
IL (1) | IL253487A0 (fr) |
MA (1) | MA41377A (fr) |
MX (1) | MX384262B (fr) |
PH (1) | PH12017501304A1 (fr) |
RU (1) | RU2017129375A (fr) |
SG (1) | SG11201705964YA (fr) |
TW (1) | TW201639556A (fr) |
WO (1) | WO2016118556A1 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016065019A1 (fr) | 2014-10-21 | 2016-04-28 | Abbvie Inc. | Promédicaments de carbidopa et de l-dopa et leur utilisation pour traiter la maladie de parkinson |
CA2984494A1 (fr) | 2015-05-06 | 2016-11-10 | Synagile Corporation | Suspensions pharmaceutiques contenant des particules de medicament, dispositifs pour leur administration, et leurs procedes d'utilisation |
WO2018017850A1 (fr) * | 2016-07-20 | 2018-01-25 | Abbvie Inc. | Gel intestinal de lévodopa et de carbidopa et méthodes d'utilisation |
AU2019379806A1 (en) | 2018-11-15 | 2021-05-27 | Abbvie Inc. | Pharmaceutical formulations for subcutaneous administration |
CN119510592A (zh) * | 2023-08-22 | 2025-02-25 | 上海汉都医药科技有限公司 | 一种含有卡比多巴的药物中肼含量的检测方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3132171A (en) | 1962-06-18 | 1964-05-05 | Strong Cobb Arner Inc | 3, 4-diphosphatophenyl-alanine and process for making same |
US4618484A (en) | 1983-03-30 | 1986-10-21 | Yale University | Composition and method for treatment of melanomas |
DE69016688T2 (de) | 1989-04-20 | 1995-10-05 | Zambon Spa | Dopamin-Medikament-Vorstufe. |
IT1255471B (it) | 1992-07-30 | 1995-11-02 | Zambon Spa | Derivati di catecolammine,processo per la loro preparazione e composizioni farmaceutiche che li contengono |
SE9203594D0 (sv) | 1992-11-30 | 1992-11-30 | Christer Nystroem | Laekemedel i dispersa system |
US6365180B1 (en) | 1998-01-20 | 2002-04-02 | Glenn A. Meyer | Oral liquid compositions |
WO2004069146A2 (fr) | 2003-02-07 | 2004-08-19 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Derives d'amide l-dopa et utilisations de ceux-ci |
CA2653683A1 (fr) | 2006-05-31 | 2007-12-06 | Solvay Pharmaceuticals Gmbh | Administration intestinale pendant 24 heures a long terme de levodopa/carbidopa |
RU2678839C2 (ru) | 2009-05-19 | 2019-02-04 | Неуродерм Лтд | Композиции для непрерывного введения ингибиторов допа-декарбоксилазы |
US20130253056A1 (en) | 2009-05-19 | 2013-09-26 | Neuroderm, Ltd. | Continuous Administration of Levodopa and/or Dopa Decarboxylase Inhibitors and Compositions for Same |
RU2537137C2 (ru) | 2009-11-09 | 2014-12-27 | Ксенопорт, Инк. | Фармацевтические композиции и пероральные дозированные формы пролекарства леводопы и способы применения |
HUE047841T2 (hu) | 2010-11-15 | 2020-05-28 | Neuroderm Ltd | L-dopa, dopa dekarboxiláz inhibitorok, katekol-o-metil transzferáz inhibitorok folyamatos adagolására szolgáló készítmények |
CN103648493A (zh) * | 2010-12-10 | 2014-03-19 | 辛纳吉勒公司 | 可皮下输注的左旋多巴前药组合物以及输注方法 |
WO2012158527A2 (fr) | 2011-05-13 | 2012-11-22 | Howmedica Osteonics | Compositions à base de composés métalliques multivalents et organophosphorés et procédés associés |
ES2833276T3 (es) | 2011-08-31 | 2021-06-14 | Abbvie Inc | Disposión de sellado para jeringa |
WO2014141261A1 (fr) | 2013-03-13 | 2014-09-18 | Neuroderm Ltd | Procédé pour le traitement de la maladie de parkinson |
EP3065808B1 (fr) * | 2013-11-05 | 2023-08-30 | SynAgile Corporation | Dispositifs et procédés pour l'administration de médicament continue par la bouche |
-
2016
- 2016-01-19 MA MA041377A patent/MA41377A/fr unknown
- 2016-01-20 CA CA2974203A patent/CA2974203A1/fr not_active Abandoned
- 2016-01-20 KR KR1020177022953A patent/KR20170103967A/ko not_active Withdrawn
- 2016-01-20 US US15/001,392 patent/US10117843B2/en active Active
- 2016-01-20 WO PCT/US2016/014005 patent/WO2016118556A1/fr active Application Filing
- 2016-01-20 CN CN202310053820.6A patent/CN116036064A/zh active Pending
- 2016-01-20 RU RU2017129375A patent/RU2017129375A/ru not_active Application Discontinuation
- 2016-01-20 EP EP24194552.6A patent/EP4470611A3/fr active Pending
- 2016-01-20 EP EP16706041.7A patent/EP3247330A1/fr not_active Withdrawn
- 2016-01-20 SG SG11201705964YA patent/SG11201705964YA/en unknown
- 2016-01-20 BR BR112017015613-0A patent/BR112017015613B1/pt active IP Right Grant
- 2016-01-20 TW TW105101753A patent/TW201639556A/zh unknown
- 2016-01-20 CN CN201680016049.3A patent/CN107427463A/zh active Pending
- 2016-01-20 AU AU2016209420A patent/AU2016209420B2/en active Active
- 2016-01-20 JP JP2017556790A patent/JP2018503686A/ja active Pending
- 2016-01-20 MX MX2017009325A patent/MX384262B/es unknown
-
2017
- 2017-07-14 IL IL253487A patent/IL253487A0/en unknown
- 2017-07-18 PH PH12017501304A patent/PH12017501304A1/en unknown
-
2018
- 2018-10-16 US US16/161,940 patent/US20190142777A1/en not_active Abandoned
-
2020
- 2020-03-18 US US16/822,892 patent/US20210046029A1/en not_active Abandoned
- 2020-12-24 JP JP2020214665A patent/JP7232235B2/ja active Active
-
2023
- 2023-02-16 JP JP2023022208A patent/JP2023058678A/ja not_active Ceased
-
2024
- 2024-07-04 JP JP2024107963A patent/JP2024129122A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP3247330A1 (fr) | 2017-11-29 |
RU2017129375A (ru) | 2019-02-21 |
IL253487A0 (en) | 2017-09-28 |
US20190142777A1 (en) | 2019-05-16 |
US20210046029A1 (en) | 2021-02-18 |
EP4470611A3 (fr) | 2025-02-19 |
JP2023058678A (ja) | 2023-04-25 |
BR112017015613A2 (pt) | 2018-03-13 |
JP2024129122A (ja) | 2024-09-26 |
MA41377A (fr) | 2017-11-28 |
PH12017501304A1 (en) | 2018-02-05 |
RU2017129375A3 (fr) | 2019-08-05 |
CN107427463A (zh) | 2017-12-01 |
MX384262B (es) | 2025-03-14 |
KR20170103967A (ko) | 2017-09-13 |
AU2016209420A1 (en) | 2017-08-03 |
US10117843B2 (en) | 2018-11-06 |
MX2017009325A (es) | 2018-02-09 |
TW201639556A (zh) | 2016-11-16 |
CA2974203A1 (fr) | 2016-07-28 |
BR112017015613B1 (pt) | 2023-11-28 |
CN116036064A (zh) | 2023-05-02 |
EP4470611A2 (fr) | 2024-12-04 |
JP2018503686A (ja) | 2018-02-08 |
JP7232235B2 (ja) | 2023-03-02 |
WO2016118556A1 (fr) | 2016-07-28 |
US20160206584A1 (en) | 2016-07-21 |
JP2021073186A (ja) | 2021-05-13 |
AU2016209420B2 (en) | 2021-05-20 |
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