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SG11201705964YA - Levodopa and carbidopa intestinal gel and methods of use - Google Patents

Levodopa and carbidopa intestinal gel and methods of use

Info

Publication number
SG11201705964YA
SG11201705964YA SG11201705964YA SG11201705964YA SG11201705964YA SG 11201705964Y A SG11201705964Y A SG 11201705964YA SG 11201705964Y A SG11201705964Y A SG 11201705964YA SG 11201705964Y A SG11201705964Y A SG 11201705964YA SG 11201705964Y A SG11201705964Y A SG 11201705964YA
Authority
SG
Singapore
Prior art keywords
levodopa
methods
intestinal gel
carbidopa intestinal
carbidopa
Prior art date
Application number
SG11201705964YA
Other languages
English (en)
Inventor
Rajkumar Conjeevaram
Alexandru Deac
Ye Huang
Sean E Mackey
Randy A Menges
Jayne B Zimmerman
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of SG11201705964YA publication Critical patent/SG11201705964YA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dispersion Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Psychology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
SG11201705964YA 2015-01-20 2016-01-20 Levodopa and carbidopa intestinal gel and methods of use SG11201705964YA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562105565P 2015-01-20 2015-01-20
US201562272922P 2015-12-30 2015-12-30
PCT/US2016/014005 WO2016118556A1 (fr) 2015-01-20 2016-01-20 Gel intestinal de lévodopa et de carbidona et procédés d'utilisation

Publications (1)

Publication Number Publication Date
SG11201705964YA true SG11201705964YA (en) 2017-08-30

Family

ID=55410198

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201705964YA SG11201705964YA (en) 2015-01-20 2016-01-20 Levodopa and carbidopa intestinal gel and methods of use

Country Status (16)

Country Link
US (3) US10117843B2 (fr)
EP (2) EP4470611A3 (fr)
JP (4) JP2018503686A (fr)
KR (1) KR20170103967A (fr)
CN (2) CN116036064A (fr)
AU (1) AU2016209420B2 (fr)
BR (1) BR112017015613B1 (fr)
CA (1) CA2974203A1 (fr)
IL (1) IL253487A0 (fr)
MA (1) MA41377A (fr)
MX (1) MX384262B (fr)
PH (1) PH12017501304A1 (fr)
RU (1) RU2017129375A (fr)
SG (1) SG11201705964YA (fr)
TW (1) TW201639556A (fr)
WO (1) WO2016118556A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016065019A1 (fr) 2014-10-21 2016-04-28 Abbvie Inc. Promédicaments de carbidopa et de l-dopa et leur utilisation pour traiter la maladie de parkinson
CA2984494A1 (fr) 2015-05-06 2016-11-10 Synagile Corporation Suspensions pharmaceutiques contenant des particules de medicament, dispositifs pour leur administration, et leurs procedes d'utilisation
WO2018017850A1 (fr) * 2016-07-20 2018-01-25 Abbvie Inc. Gel intestinal de lévodopa et de carbidopa et méthodes d'utilisation
AU2019379806A1 (en) 2018-11-15 2021-05-27 Abbvie Inc. Pharmaceutical formulations for subcutaneous administration
CN119510592A (zh) * 2023-08-22 2025-02-25 上海汉都医药科技有限公司 一种含有卡比多巴的药物中肼含量的检测方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3132171A (en) 1962-06-18 1964-05-05 Strong Cobb Arner Inc 3, 4-diphosphatophenyl-alanine and process for making same
US4618484A (en) 1983-03-30 1986-10-21 Yale University Composition and method for treatment of melanomas
DE69016688T2 (de) 1989-04-20 1995-10-05 Zambon Spa Dopamin-Medikament-Vorstufe.
IT1255471B (it) 1992-07-30 1995-11-02 Zambon Spa Derivati di catecolammine,processo per la loro preparazione e composizioni farmaceutiche che li contengono
SE9203594D0 (sv) 1992-11-30 1992-11-30 Christer Nystroem Laekemedel i dispersa system
US6365180B1 (en) 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
WO2004069146A2 (fr) 2003-02-07 2004-08-19 Yissum Research Development Company Of The Hebrew University Of Jerusalem Derives d'amide l-dopa et utilisations de ceux-ci
CA2653683A1 (fr) 2006-05-31 2007-12-06 Solvay Pharmaceuticals Gmbh Administration intestinale pendant 24 heures a long terme de levodopa/carbidopa
RU2678839C2 (ru) 2009-05-19 2019-02-04 Неуродерм Лтд Композиции для непрерывного введения ингибиторов допа-декарбоксилазы
US20130253056A1 (en) 2009-05-19 2013-09-26 Neuroderm, Ltd. Continuous Administration of Levodopa and/or Dopa Decarboxylase Inhibitors and Compositions for Same
RU2537137C2 (ru) 2009-11-09 2014-12-27 Ксенопорт, Инк. Фармацевтические композиции и пероральные дозированные формы пролекарства леводопы и способы применения
HUE047841T2 (hu) 2010-11-15 2020-05-28 Neuroderm Ltd L-dopa, dopa dekarboxiláz inhibitorok, katekol-o-metil transzferáz inhibitorok folyamatos adagolására szolgáló készítmények
CN103648493A (zh) * 2010-12-10 2014-03-19 辛纳吉勒公司 可皮下输注的左旋多巴前药组合物以及输注方法
WO2012158527A2 (fr) 2011-05-13 2012-11-22 Howmedica Osteonics Compositions à base de composés métalliques multivalents et organophosphorés et procédés associés
ES2833276T3 (es) 2011-08-31 2021-06-14 Abbvie Inc Disposión de sellado para jeringa
WO2014141261A1 (fr) 2013-03-13 2014-09-18 Neuroderm Ltd Procédé pour le traitement de la maladie de parkinson
EP3065808B1 (fr) * 2013-11-05 2023-08-30 SynAgile Corporation Dispositifs et procédés pour l'administration de médicament continue par la bouche

Also Published As

Publication number Publication date
EP3247330A1 (fr) 2017-11-29
RU2017129375A (ru) 2019-02-21
IL253487A0 (en) 2017-09-28
US20190142777A1 (en) 2019-05-16
US20210046029A1 (en) 2021-02-18
EP4470611A3 (fr) 2025-02-19
JP2023058678A (ja) 2023-04-25
BR112017015613A2 (pt) 2018-03-13
JP2024129122A (ja) 2024-09-26
MA41377A (fr) 2017-11-28
PH12017501304A1 (en) 2018-02-05
RU2017129375A3 (fr) 2019-08-05
CN107427463A (zh) 2017-12-01
MX384262B (es) 2025-03-14
KR20170103967A (ko) 2017-09-13
AU2016209420A1 (en) 2017-08-03
US10117843B2 (en) 2018-11-06
MX2017009325A (es) 2018-02-09
TW201639556A (zh) 2016-11-16
CA2974203A1 (fr) 2016-07-28
BR112017015613B1 (pt) 2023-11-28
CN116036064A (zh) 2023-05-02
EP4470611A2 (fr) 2024-12-04
JP2018503686A (ja) 2018-02-08
JP7232235B2 (ja) 2023-03-02
WO2016118556A1 (fr) 2016-07-28
US20160206584A1 (en) 2016-07-21
JP2021073186A (ja) 2021-05-13
AU2016209420B2 (en) 2021-05-20

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