SG11201701925XA - Human-derived anti-dipeptide repeats (dprs) antibody - Google Patents
Human-derived anti-dipeptide repeats (dprs) antibodyInfo
- Publication number
- SG11201701925XA SG11201701925XA SG11201701925XA SG11201701925XA SG11201701925XA SG 11201701925X A SG11201701925X A SG 11201701925XA SG 11201701925X A SG11201701925X A SG 11201701925XA SG 11201701925X A SG11201701925X A SG 11201701925XA SG 11201701925X A SG11201701925X A SG 11201701925XA
- Authority
- SG
- Singapore
- Prior art keywords
- dprs
- antibody
- human
- derived anti
- dipeptide repeats
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6025—Nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP14187180 | 2014-09-30 | ||
EP15180310 | 2015-08-07 | ||
PCT/EP2015/072516 WO2016050822A2 (en) | 2014-09-30 | 2015-09-30 | Human-derived anti-dipeptide repeats (dprs) antibody |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201701925XA true SG11201701925XA (en) | 2017-04-27 |
Family
ID=54238439
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201902850TA SG10201902850TA (en) | 2014-09-30 | 2015-09-30 | Human-derived anti-dipeptide repeats (dprs) antibody |
SG11201701925XA SG11201701925XA (en) | 2014-09-30 | 2015-09-30 | Human-derived anti-dipeptide repeats (dprs) antibody |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10201902850TA SG10201902850TA (en) | 2014-09-30 | 2015-09-30 | Human-derived anti-dipeptide repeats (dprs) antibody |
Country Status (17)
Country | Link |
---|---|
US (3) | US10392447B2 (en) |
EP (1) | EP3201228A2 (en) |
JP (5) | JP6637971B2 (en) |
KR (2) | KR20230104759A (en) |
CN (1) | CN108064248B (en) |
AU (2) | AU2015326911B2 (en) |
BR (1) | BR112017006598A2 (en) |
CA (1) | CA2960925A1 (en) |
CO (1) | CO2017002804A2 (en) |
IL (2) | IL278941B (en) |
MX (1) | MX2017004213A (en) |
MY (1) | MY180054A (en) |
NZ (1) | NZ729808A (en) |
PH (1) | PH12017500489A1 (en) |
SG (2) | SG10201902850TA (en) |
WO (1) | WO2016050822A2 (en) |
ZA (2) | ZA201701733B (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6570447B2 (en) | 2012-10-15 | 2019-09-04 | アイオーニス ファーマシューティカルズ, インコーポレーテッドIonis Pharmaceuticals,Inc. | Composition for modulating C9ORF72 expression |
WO2014062736A1 (en) | 2012-10-15 | 2014-04-24 | Isis Pharmaceuticals, Inc. | Methods for monitoring c9orf72 expression |
EP3055414A4 (en) | 2013-10-11 | 2017-07-19 | Ionis Pharmaceuticals, Inc. | Compositions for modulating c9orf72 expression |
NZ729808A (en) | 2014-09-30 | 2022-02-25 | Neurimmune Holding Ag | Human-derived anti-dipeptide repeats (dprs) antibody |
US11260073B2 (en) | 2015-11-02 | 2022-03-01 | Ionis Pharmaceuticals, Inc. | Compounds and methods for modulating C90RF72 |
CA3097872A1 (en) * | 2018-04-27 | 2019-10-31 | Biogen Ma Inc. | Human-derived anti-(poly-ga) dipeptide repeat (dpr) antibody |
CA3107352A1 (en) * | 2018-07-23 | 2020-01-30 | Enclear Therapies, Inc. | Methods of treating neurological disorders |
WO2020072428A1 (en) * | 2018-10-01 | 2020-04-09 | United Neuroscience | Peptide immunogen constructs directed against dipeptide repeat proteins from c9orf72 |
AU2019371814A1 (en) | 2018-10-29 | 2021-06-17 | Biogen Ma Inc. | Humanized and stabilized fc5 variants for enhancement of blood brain barrier transport |
WO2020107037A1 (en) * | 2018-11-25 | 2020-05-28 | President And Fellows Of Harvard College | Compounds and methods for treating neurodegenerative diseases |
MA54383A (en) | 2018-12-06 | 2021-10-13 | Biogen Ma Inc | NEUROFILAMENTOUS PROTEIN TO GUIDE THERAPEUTIC INTERVENTION IN AMYOTROPHIC LATERAL SCLEROSIS |
CN110470837B (en) * | 2019-08-30 | 2022-09-16 | 苏州西山生物技术有限公司 | Method for detecting simian SRV by using simian SRV GP20 protein and kit thereof |
WO2023099788A1 (en) | 2021-12-03 | 2023-06-08 | Neurimmune Ag | Novel potency assay for antibody-based drugs and useful means therefor |
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WO1987005330A1 (en) | 1986-03-07 | 1987-09-11 | Michel Louis Eugene Bergh | Method for enhancing glycoprotein stability |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
EP0623679B1 (en) | 1987-05-21 | 2003-06-25 | Micromet AG | Targeted multifunctional proteins |
US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
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JPH02503867A (en) | 1988-04-15 | 1990-11-15 | プロテイン デザイン ラブズ インコーポレーテッド | IL-2 receptor-specific chimeric antibody |
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NZ729808A (en) | 2014-09-30 | 2022-02-25 | Neurimmune Holding Ag | Human-derived anti-dipeptide repeats (dprs) antibody |
CA2874083C (en) * | 2014-12-05 | 2024-01-02 | Universite Laval | Tdp-43-binding polypeptides useful for the treatment of neurodegenerative diseases |
-
2015
- 2015-09-30 NZ NZ729808A patent/NZ729808A/en unknown
- 2015-09-30 MY MYPI2017700811A patent/MY180054A/en unknown
- 2015-09-30 CN CN201580064969.8A patent/CN108064248B/en active Active
- 2015-09-30 CA CA2960925A patent/CA2960925A1/en active Pending
- 2015-09-30 WO PCT/EP2015/072516 patent/WO2016050822A2/en not_active Application Discontinuation
- 2015-09-30 KR KR1020237021848A patent/KR20230104759A/en not_active Ceased
- 2015-09-30 US US15/508,343 patent/US10392447B2/en active Active
- 2015-09-30 AU AU2015326911A patent/AU2015326911B2/en active Active
- 2015-09-30 BR BR112017006598A patent/BR112017006598A2/en not_active Application Discontinuation
- 2015-09-30 IL IL278941A patent/IL278941B/en unknown
- 2015-09-30 JP JP2017517086A patent/JP6637971B2/en active Active
- 2015-09-30 EP EP15771953.5A patent/EP3201228A2/en active Pending
- 2015-09-30 SG SG10201902850TA patent/SG10201902850TA/en unknown
- 2015-09-30 KR KR1020177011599A patent/KR102594327B1/en active Active
- 2015-09-30 MX MX2017004213A patent/MX2017004213A/en unknown
- 2015-09-30 SG SG11201701925XA patent/SG11201701925XA/en unknown
-
2017
- 2017-03-09 ZA ZA2017/01733A patent/ZA201701733B/en unknown
- 2017-03-09 IL IL251081A patent/IL251081A0/en unknown
- 2017-03-14 PH PH12017500489A patent/PH12017500489A1/en unknown
- 2017-03-24 CO CONC2017/0002804A patent/CO2017002804A2/en unknown
-
2018
- 2018-12-07 ZA ZA2018/08270A patent/ZA201808270B/en unknown
-
2019
- 2019-06-07 US US16/434,654 patent/US10961322B2/en active Active
- 2019-11-26 JP JP2019213035A patent/JP2020031660A/en not_active Withdrawn
-
2021
- 2021-08-20 JP JP2021134979A patent/JP2021177788A/en not_active Withdrawn
- 2021-10-06 AU AU2021245147A patent/AU2021245147B2/en active Active
-
2023
- 2023-10-23 US US18/492,146 patent/US20240279361A1/en active Pending
-
2024
- 2024-04-26 JP JP2024072910A patent/JP2024102176A/en active Pending
- 2024-04-26 JP JP2024072911A patent/JP2024096261A/en active Pending
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