SG11201507411TA - Guanidinobenzoic acid ester compound - Google Patents
Guanidinobenzoic acid ester compoundInfo
- Publication number
- SG11201507411TA SG11201507411TA SG11201507411TA SG11201507411TA SG11201507411TA SG 11201507411T A SG11201507411T A SG 11201507411TA SG 11201507411T A SG11201507411T A SG 11201507411TA SG 11201507411T A SG11201507411T A SG 11201507411TA SG 11201507411T A SG11201507411T A SG 11201507411TA
- Authority
- SG
- Singapore
- Prior art keywords
- acid ester
- ester compound
- guanidinobenzoic acid
- guanidinobenzoic
- compound
- Prior art date
Links
- -1 Guanidinobenzoic acid ester compound Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D333/40—Thiophene-2-carboxylic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013050011 | 2013-03-13 | ||
| PCT/JP2014/056601 WO2014142219A1 (ja) | 2013-03-13 | 2014-03-13 | グアニジノ安息香酸エステル化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201507411TA true SG11201507411TA (en) | 2015-10-29 |
Family
ID=51536870
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201507411TA SG11201507411TA (en) | 2013-03-13 | 2014-03-13 | Guanidinobenzoic acid ester compound |
| SG10201707504VA SG10201707504VA (en) | 2013-03-13 | 2014-03-13 | Guanidinobenzoic acid ester compound |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201707504VA SG10201707504VA (en) | 2013-03-13 | 2014-03-13 | Guanidinobenzoic acid ester compound |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US9969709B2 (pl) |
| EP (1) | EP2975023B1 (pl) |
| JP (1) | JP6314129B2 (pl) |
| KR (1) | KR102145649B1 (pl) |
| CN (1) | CN105051008B (pl) |
| AU (1) | AU2014230583B2 (pl) |
| BR (1) | BR112015022762B1 (pl) |
| CA (1) | CA2905606C (pl) |
| CY (1) | CY1120552T1 (pl) |
| DK (1) | DK2975023T3 (pl) |
| ES (1) | ES2684045T3 (pl) |
| HR (1) | HRP20181371T1 (pl) |
| HU (1) | HUE039526T2 (pl) |
| IL (1) | IL241541B (pl) |
| LT (1) | LT2975023T (pl) |
| MX (1) | MX373838B (pl) |
| MY (1) | MY194604A (pl) |
| PH (1) | PH12015502023B1 (pl) |
| PL (1) | PL2975023T3 (pl) |
| PT (1) | PT2975023T (pl) |
| RS (1) | RS57568B1 (pl) |
| RU (1) | RU2661895C2 (pl) |
| SG (2) | SG11201507411TA (pl) |
| SI (1) | SI2975023T1 (pl) |
| SM (1) | SMT201800440T1 (pl) |
| TR (1) | TR201809418T4 (pl) |
| TW (1) | TWI666196B (pl) |
| UA (1) | UA118668C2 (pl) |
| WO (1) | WO2014142219A1 (pl) |
| ZA (1) | ZA201506745B (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2905606C (en) | 2013-03-13 | 2021-03-09 | Astellas Pharma Inc. | Guanidino benzoic acid esters useful in treating renal disorders |
| US9428470B2 (en) | 2014-02-13 | 2016-08-30 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| US9346776B2 (en) * | 2014-02-13 | 2016-05-24 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound |
| JP2018080109A (ja) * | 2015-03-16 | 2018-05-24 | 武田薬品工業株式会社 | 治療剤 |
| EP3275874B1 (en) * | 2015-03-27 | 2019-10-30 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound |
| CN105218289B (zh) * | 2015-10-15 | 2017-08-01 | 浙江大学 | 一种不饱和脂肪酸原位加氢脱羧制备长链烷烃的方法 |
| KR20200075867A (ko) | 2017-11-02 | 2020-06-26 | 우베 고산 가부시키가이샤 | 단백 분해 효소의 쌍두형 저해제 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5289640A (en) | 1976-01-21 | 1977-07-27 | Ono Pharmaceut Co Ltd | Guanidinobenzoic acid derivatives, and antiplasmin agents and remedies for pancreas diseases containing the said guanidinobensolc acid deriv atives |
| JPS5753454A (en) | 1980-09-16 | 1982-03-30 | Torii Yakuhin Kk | Guanidinobenzoate and anticomplementary agent |
| AU527371B2 (en) | 1980-09-16 | 1983-03-03 | Torii & Co., Ltd. | Amidine |
| JP2886586B2 (ja) | 1989-12-28 | 1999-04-26 | 雪印乳業株式会社 | 新規グアニジノ安息香酸誘導体及びその酸付加塩 |
| US5116985A (en) | 1989-12-28 | 1992-05-26 | Snow Brand Milk Products Co., Ltd. | Isoquinoline derivatives and salts thereof |
| JPH0446148A (ja) | 1990-06-08 | 1992-02-17 | Asahi Chem Ind Co Ltd | ４―グアニジノ安息香酸フェニルエステル誘導体およびそれらを含有する蛋白分解酵素阻害剤 |
| JPH06192085A (ja) | 1992-08-31 | 1994-07-12 | Yuji Inada | ダニアレルギー治療剤 |
| WO1994013631A1 (en) | 1992-12-10 | 1994-06-23 | Teikoku Chemical Industries Co., Ltd. | Propionic acid derivative |
| JPH0753500A (ja) | 1993-08-16 | 1995-02-28 | Sanwa Kagaku Kenkyusho Co Ltd | グアニジノ安息香酸誘導体及びこれらを有効成分とする蛋白分解酵素阻害剤 |
| JPH0848664A (ja) | 1994-08-05 | 1996-02-20 | Hisamitsu Pharmaceut Co Inc | 新規なグアニジノ安息香酸エステル誘導体 |
| JPH09124571A (ja) * | 1995-11-01 | 1997-05-13 | Japan Tobacco Inc | アミド化合物及びその用途 |
| US6388122B1 (en) * | 1996-04-10 | 2002-05-14 | Ono Pharmaceutical Co., Ltd. | Tryptase inhibitor and novel guanidino derivatives |
| JPH10101556A (ja) | 1996-09-27 | 1998-04-21 | Ono Pharmaceut Co Ltd | ファクターｄ阻害剤 |
| JPH10251239A (ja) | 1997-03-14 | 1998-09-22 | Mochida Pharmaceut Co Ltd | 新規４ｈ−３，１−ベンゾオキサジン−４−オン誘導体 |
| JPH10306025A (ja) | 1997-05-07 | 1998-11-17 | Touin Yokohama Univ | 花粉プロテアーゼ阻害剤 |
| EP1815865A4 (en) | 2004-11-08 | 2010-08-25 | Ono Pharmaceutical Co | THERAPEUTIC AGENT AGAINST DIABETES WITH A PROTEASE-INHIBITING COMPOUND |
| EP1843819A2 (en) | 2004-11-15 | 2007-10-17 | Obe Therapy Biotechnology S.A.S. | Methods of reducing body fat |
| ATE401007T1 (de) | 2004-11-26 | 2008-08-15 | Nutricia Nv | Kleinkindernahrung mit proteasehemmer |
| DE602006008576D1 (de) | 2005-01-31 | 2009-10-01 | Merck & Co Inc | Antidiabetische bicyclische verbindungen |
| AU2007208495A1 (en) | 2006-01-12 | 2007-08-02 | Merck Sharp & Dohme Corp. | Hydroxyalkylarylamide derivatives |
| SI2225261T1 (sl) | 2007-12-03 | 2016-07-29 | Obe Therapy Biotechnology | Boropeptidni inhibitorji enteropeptidaze in njihove uporabe pri zdravljenju debelosti, prekomerne teže in/ali bolezni, povezanih z nenormalno presnovo maščob |
| WO2011071048A1 (ja) | 2009-12-07 | 2011-06-16 | 味の素株式会社 | ヘテロアリールカルボン酸エステル誘導体 |
| ES2618024T3 (es) | 2011-06-07 | 2017-06-20 | Ea Pharma Co., Ltd. | Derivado de éster de ácido carboxílico heterocíclico |
| AU2012309438A1 (en) | 2011-09-15 | 2014-03-27 | Astellas Pharma Inc. | Guanidinobenzoic acid compound |
| WO2013102899A1 (en) | 2012-01-03 | 2013-07-11 | Oramed Ltd. | Methods and compositions for treating diabetes |
| US9024044B2 (en) | 2012-06-14 | 2015-05-05 | Ajinomoto Co., Inc. | Heteroarylcarboxylic acid ester derivative |
| EP2941267B1 (en) | 2013-01-03 | 2022-11-16 | Oramed Ltd. | Compositions for use in treating nafld |
| KR20150124985A (ko) | 2013-03-08 | 2015-11-06 | 암젠 인크 | 베타-세크레타제 억제제로서 퍼플루오르화된 사이클로프로필 융합된 1,3-옥사진-2-아민 화합물 및 그의 사용 방법 |
| CA2905606C (en) | 2013-03-13 | 2021-03-09 | Astellas Pharma Inc. | Guanidino benzoic acid esters useful in treating renal disorders |
| US9428470B2 (en) | 2014-02-13 | 2016-08-30 | Takeda Pharmaceutical Company Limited | Heterocyclic compound |
| US9346776B2 (en) | 2014-02-13 | 2016-05-24 | Takeda Pharmaceutical Company Limited | Fused heterocyclic compound |
-
2014
- 2014-03-13 CA CA2905606A patent/CA2905606C/en active Active
- 2014-03-13 HR HRP20181371TT patent/HRP20181371T1/hr unknown
- 2014-03-13 RU RU2015143562A patent/RU2661895C2/ru active
- 2014-03-13 JP JP2015505541A patent/JP6314129B2/ja active Active
- 2014-03-13 SI SI201430865T patent/SI2975023T1/sl unknown
- 2014-03-13 DK DK14763790.4T patent/DK2975023T3/en active
- 2014-03-13 HU HUE14763790A patent/HUE039526T2/hu unknown
- 2014-03-13 UA UAA201509922A patent/UA118668C2/uk unknown
- 2014-03-13 AU AU2014230583A patent/AU2014230583B2/en active Active
- 2014-03-13 SG SG11201507411TA patent/SG11201507411TA/en unknown
- 2014-03-13 BR BR112015022762-7A patent/BR112015022762B1/pt active IP Right Grant
- 2014-03-13 PL PL14763790T patent/PL2975023T3/pl unknown
- 2014-03-13 SG SG10201707504VA patent/SG10201707504VA/en unknown
- 2014-03-13 LT LTEP14763790.4T patent/LT2975023T/lt unknown
- 2014-03-13 TR TR2018/09418T patent/TR201809418T4/tr unknown
- 2014-03-13 TW TW103109057A patent/TWI666196B/zh active
- 2014-03-13 MY MYPI2015703099A patent/MY194604A/en unknown
- 2014-03-13 US US14/775,274 patent/US9969709B2/en active Active
- 2014-03-13 EP EP14763790.4A patent/EP2975023B1/en active Active
- 2014-03-13 KR KR1020157027906A patent/KR102145649B1/ko active Active
- 2014-03-13 ES ES14763790.4T patent/ES2684045T3/es active Active
- 2014-03-13 CN CN201480014813.4A patent/CN105051008B/zh active Active
- 2014-03-13 WO PCT/JP2014/056601 patent/WO2014142219A1/ja active Application Filing
- 2014-03-13 RS RS20180861A patent/RS57568B1/sr unknown
- 2014-03-13 PT PT147637904T patent/PT2975023T/pt unknown
- 2014-03-13 SM SM20180440T patent/SMT201800440T1/it unknown
- 2014-03-13 MX MX2015012604A patent/MX373838B/es active IP Right Grant
-
2015
- 2015-09-09 PH PH12015502023A patent/PH12015502023B1/en unknown
- 2015-09-10 IL IL241541A patent/IL241541B/en active IP Right Grant
- 2015-09-11 ZA ZA2015/06745A patent/ZA201506745B/en unknown
-
2018
- 2018-08-09 CY CY20181100832T patent/CY1120552T1/el unknown
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