SG11201507227UA - Pyridin-4-yl derivatives - Google Patents

Pyridin-4-yl derivatives

Info

Publication number: SG11201507227UA
Authority: SG; Singapore
Prior art keywords: pyridin; derivatives
Prior art date: 2013-03-15

Application number

SG11201507227UA

Inventor

Martin Bolli

Cyrille Lescop

Oliver Nayler

Beat Steiner

Original Assignee

Actelion Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-03-15

Filing date

2014-03-14

Publication date

2015-10-29

2014-03-14 Application filed by Actelion Pharmaceuticals Ltd filed Critical Actelion Pharmaceuticals Ltd

2015-10-29 Publication of SG11201507227UA publication Critical patent/SG11201507227UA/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Immunology (AREA)
Pulmonology (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Rheumatology (AREA)
Transplantation (AREA)
Emergency Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Pain & Pain Management (AREA)
Oncology (AREA)
Ophthalmology & Optometry (AREA)
Dermatology (AREA)
Otolaryngology (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epidemiology (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)

SG11201507227UA 2013-03-15 2014-03-14 Pyridin-4-yl derivatives SG11201507227UA (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP13159482		2013-03-15
PCT/IB2014/059794 WO2014141171A1 (en)	2013-03-15	2014-03-14	Pyridin-4-yl derivatives

Publications (1)

Publication Number	Publication Date
SG11201507227UA true SG11201507227UA (en)	2015-10-29

Family

ID=47877933

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG11201507227UA SG11201507227UA (en)	2013-03-15	2014-03-14	Pyridin-4-yl derivatives

Country Status (33)

Country	Link
US (1)	US9617250B2 (en)
EP (1)	EP2970236B1 (en)
JP (1)	JP6387361B2 (en)
KR (1)	KR102212975B1 (en)
CN (1)	CN105189487B (en)
AR (1)	AR095523A1 (en)
AU (1)	AU2014229217B2 (en)
BR (1)	BR112015023161B1 (en)
CA (1)	CA2900910C (en)
CL (1)	CL2015002620A1 (en)
CY (1)	CY1119619T1 (en)
DK (1)	DK2970236T3 (en)
EA (1)	EA029309B1 (en)
ES (1)	ES2649475T3 (en)
HR (1)	HRP20171763T1 (en)
HU (1)	HUE035154T2 (en)
IL (1)	IL241363B (en)
LT (1)	LT2970236T (en)
MA (1)	MA38482B1 (en)
MX (1)	MX363545B (en)
MY (1)	MY173573A (en)
NO (1)	NO2970236T3 (en)
NZ (1)	NZ713080A (en)
PH (1)	PH12015502118A1 (en)
PL (1)	PL2970236T3 (en)
PT (1)	PT2970236T (en)
SA (1)	SA515361104B1 (en)
SG (1)	SG11201507227UA (en)
SI (1)	SI2970236T1 (en)
TW (1)	TWI623534B (en)
UA (1)	UA115357C2 (en)
WO (1)	WO2014141171A1 (en)
ZA (1)	ZA201507657B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2014110574A1 (en)	2013-01-14	2014-07-17	Incyte Corporation	Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors
ES2790419T3 (en)	2013-01-15	2020-10-27	Incyte Holdings Corp	Thiazolecarboxamide and pyridinecarboxamide compounds useful as PIM kinase inhibitors
US9556197B2 (en)	2013-08-23	2017-01-31	Incyte Corporation	Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors
US9580418B2 (en)	2014-07-14	2017-02-28	Incyte Corporation	Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors
WO2016010897A1 (en)	2014-07-14	2016-01-21	Incyte Corporation	Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors
PH12017502097B1 (en)	2015-05-20	2023-05-05	Idorsia Pharmaceuticals Ltd	Crystalline form of the compound (s)-3-{4-[5-(2-cyclopentyl-6-methoxy-pyridin-4-yl)-[1,2,4]oxadiazol-3-yl]-2-ethyl-6-methyl-phenoxy}-propane-1,2-diol
US9540347B2 (en)	2015-05-29	2017-01-10	Incyte Corporation	Pyridineamine compounds useful as Pim kinase inhibitors
WO2017004610A1 (en) *	2015-07-02	2017-01-05	Exelixis, Inc.	Tercyclic s1p3-sparing, s1p1 receptor agonists
AR105967A1 (en)	2015-09-09	2017-11-29	Incyte Corp	SALTS OF A PIM QUINASA INHIBITOR
WO2017059251A1 (en)	2015-10-02	2017-04-06	Incyte Corporation	Heterocyclic compounds useful as pim kinase inhibitors
TW201924683A (en)	2017-12-08	2019-07-01	美商英塞特公司	Low dose combination therapy for treatment of myeloproliferative neoplasms

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1991015583A1 (en)	1990-04-05	1991-10-17	The American National Red Cross	A protein family related to immediate-early protein expressed by human endothelial cells during differentiation
EP1070080A4 (en)	1998-03-09	2004-12-29	Smithkline Beecham Corp	HUMAN EDG-1c POLYNUCLEOTIDES AND POLYPEPTIDES AND METHODS OF USE
WO2004035538A1 (en)	2002-10-15	2004-04-29	Merck & Co., Inc.	Process for making azetidine-3-carboxylic acid
CN101511827B (en) *	2006-09-07	2012-02-01	埃科特莱茵药品有限公司	Pyridin-4-yl derivatives as immunomodulating agents
CA2661315C (en) *	2006-09-08	2015-11-24	Actelion Pharmaceuticals Ltd	Pyridin-3-yl derivatives as immunomodulating agents
CN101522645B (en)	2006-09-21	2013-01-09	埃科特莱茵药品有限公司	Phenyl derivatives and their use as immunomodulators
SI2125797T1 (en)	2007-03-16	2014-03-31	Actelion Pharmaceuticals Ltd.	Amino- pyridine derivatives as s1p1 /edg1 receptor agonists
BRPI0815190A2 (en)	2007-08-17	2015-03-31	Actelion Pharmaceuticals Ltd	Pyridine derivative compound, pharmaceutical composition comprising it and use thereof
BRPI0818457A2 (en)	2007-10-04	2015-04-14	Merck Serono Sa	OXADIAZOL DERIVATIVES
NZ585775A (en)	2007-11-01	2011-12-22	Actelion Pharmaceuticals Ltd	Novel pyrimidine derivatives
US20110046170A1 (en)	2008-03-06	2011-02-24	Martin Bolli	Novel pyrimidine-pyridine derivatives
EP2262799B1 (en)	2008-03-06	2012-07-04	Actelion Pharmaceuticals Ltd.	Pyridine compounds
NZ588438A (en)	2008-03-07	2012-05-25	Actelion Pharmaceuticals Ltd	Pyridin-2-yl oxadiazole derivatives as immunomodulating agents
AU2009220893A1 (en)	2008-03-07	2009-09-11	Actelion Pharmaceuticals Ltd	Novel aminomethyl benzene derivatives
DK2291080T3 (en) *	2008-05-14	2015-12-07	Scripps Research Inst	Novel modulator of sphingosinphosphatreceptorer
CA2752804C (en)	2009-03-03	2017-04-04	Anna Quattropani	Oxazole pyridine derivatives useful as s1p1 receptor agonists
EP2454255B1 (en)	2009-07-16	2013-11-06	Actelion Pharmaceuticals Ltd.	Pyridin-4-yl derivatives as s1p1/edg1 agonists
TW201120016A (en)	2009-12-08	2011-06-16	Abbott Lab	Novel oxadiazole compounds
ES2544086T3 (en)	2011-01-19	2015-08-27	Actelion Pharmaceuticals Ltd.	2-Methoxy-pyridin-4-yl derivatives

2014
- 2014-03-14 MA MA38482A patent/MA38482B1/en unknown
- 2014-03-14 KR KR1020157028486A patent/KR102212975B1/en not_active Expired - Fee Related
- 2014-03-14 NO NO14715427A patent/NO2970236T3/no unknown
- 2014-03-14 PL PL14715427T patent/PL2970236T3/en unknown
- 2014-03-14 UA UAA201510003A patent/UA115357C2/en unknown
- 2014-03-14 DK DK14715427.2T patent/DK2970236T3/en active
- 2014-03-14 WO PCT/IB2014/059794 patent/WO2014141171A1/en not_active Ceased
- 2014-03-14 SI SI201430428T patent/SI2970236T1/en unknown
- 2014-03-14 BR BR112015023161-6A patent/BR112015023161B1/en not_active IP Right Cessation
- 2014-03-14 ES ES14715427.2T patent/ES2649475T3/en active Active
- 2014-03-14 JP JP2015562523A patent/JP6387361B2/en not_active Expired - Fee Related
- 2014-03-14 PT PT147154272T patent/PT2970236T/en unknown
- 2014-03-14 US US14/777,444 patent/US9617250B2/en active Active
- 2014-03-14 AR ARP140101131A patent/AR095523A1/en active IP Right Grant
- 2014-03-14 CA CA2900910A patent/CA2900910C/en active Active
- 2014-03-14 NZ NZ713080A patent/NZ713080A/en not_active IP Right Cessation
- 2014-03-14 SG SG11201507227UA patent/SG11201507227UA/en unknown
- 2014-03-14 LT LTEP14715427.2T patent/LT2970236T/en unknown
- 2014-03-14 CN CN201480016238.1A patent/CN105189487B/en not_active Expired - Fee Related
- 2014-03-14 AU AU2014229217A patent/AU2014229217B2/en not_active Ceased
- 2014-03-14 MY MYPI2015703154A patent/MY173573A/en unknown
- 2014-03-14 EP EP14715427.2A patent/EP2970236B1/en active Active
- 2014-03-14 HR HRP20171763TT patent/HRP20171763T1/en unknown
- 2014-03-14 EA EA201500931A patent/EA029309B1/en not_active IP Right Cessation
- 2014-03-14 MX MX2015012293A patent/MX363545B/en unknown
- 2014-03-14 TW TW103109288A patent/TWI623534B/en not_active IP Right Cessation
- 2014-03-14 HU HUE14715427A patent/HUE035154T2/en unknown
2015
- 2015-09-09 IL IL241363A patent/IL241363B/en active IP Right Grant
- 2015-09-11 CL CL2015002620A patent/CL2015002620A1/en unknown
- 2015-09-14 SA SA515361104A patent/SA515361104B1/en unknown
- 2015-09-14 PH PH12015502118A patent/PH12015502118A1/en unknown
- 2015-10-14 ZA ZA2015/07657A patent/ZA201507657B/en unknown
2017
- 2017-11-24 CY CY20171101239T patent/CY1119619T1/en unknown

Also Published As

Publication number	Publication date
CA2900910A1 (en)	2014-09-18
DK2970236T3 (en)	2017-10-16
MX2015012293A (en)	2015-12-16
EP2970236B1 (en)	2017-08-30
JP6387361B2 (en)	2018-09-05
IL241363A0 (en)	2015-11-30
TWI623534B (en)	2018-05-11
UA115357C2 (en)	2017-10-25
CA2900910C (en)	2021-03-30
AU2014229217B2 (en)	2017-12-14
EP2970236A1 (en)	2016-01-20
KR102212975B1 (en)	2021-02-05
MA38482B1 (en)	2018-11-30
PH12015502118B1 (en)	2016-01-25
US20160031866A1 (en)	2016-02-04
BR112015023161A8 (en)	2021-06-22
HUE035154T2 (en)	2018-05-02
SA515361104B1 (en)	2016-06-28
CY1119619T1 (en)	2018-04-04
CN105189487A (en)	2015-12-23
PH12015502118A1 (en)	2016-01-25
PL2970236T3 (en)	2018-01-31
PT2970236T (en)	2017-11-30
MX363545B (en)	2019-03-27
ZA201507657B (en)	2022-08-31
EA029309B1 (en)	2018-03-30
WO2014141171A1 (en)	2014-09-18
BR112015023161B1 (en)	2022-11-16
AR095523A1 (en)	2015-10-21
LT2970236T (en)	2017-11-10
US9617250B2 (en)	2017-04-11
ES2649475T3 (en)	2018-01-12
TW201443044A (en)	2014-11-16
CL2015002620A1 (en)	2016-03-18
HRP20171763T1 (en)	2017-12-29
NO2970236T3 (en)	2018-01-27
MY173573A (en)	2020-02-04
AU2014229217A1 (en)	2015-11-05
JP2016512227A (en)	2016-04-25
CN105189487B (en)	2017-12-26
KR20150128947A (en)	2015-11-18
SI2970236T1 (en)	2017-11-30
IL241363B (en)	2018-11-29
EA201500931A1 (en)	2016-03-31
MA38482A1 (en)	2017-12-29
HK1220454A1 (en)	2017-05-05
NZ713080A (en)	2020-06-26
BR112015023161A2 (en)	2017-07-18

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