SG11201505272QA - Age-related macular degeneration treatment - Google Patents
Age-related macular degeneration treatmentInfo
- Publication number
- SG11201505272QA SG11201505272QA SG11201505272QA SG11201505272QA SG11201505272QA SG 11201505272Q A SG11201505272Q A SG 11201505272QA SG 11201505272Q A SG11201505272Q A SG 11201505272QA SG 11201505272Q A SG11201505272Q A SG 11201505272QA SG 11201505272Q A SG11201505272Q A SG 11201505272QA
- Authority
- SG
- Singapore
- Prior art keywords
- age
- macular degeneration
- related macular
- degeneration treatment
- treatment
- Prior art date
Links
- 206010064930 age-related macular degeneration Diseases 0.000 title 1
- 208000002780 macular degeneration Diseases 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21047—Alternative-complement-pathway C3/C5 convertase (3.4.21.47), i.e. properdin factor B
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
- C12N2310/141—MicroRNAs, miRNAs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
- C12N2310/3519—Fusion with another nucleic acid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/50—Physical structure
- C12N2310/53—Physical structure partially self-complementary or closed
- C12N2310/531—Stem-loop; Hairpin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2330/00—Production
- C12N2330/50—Biochemical production, i.e. in a transformed host cell
- C12N2330/51—Specially adapted vectors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361750086P | 2013-01-08 | 2013-01-08 | |
| PCT/AU2014/000007 WO2014107763A1 (en) | 2013-01-08 | 2014-01-08 | Age-related macular degeneration treatment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201505272QA true SG11201505272QA (en) | 2015-08-28 |
Family
ID=51166430
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201505272QA SG11201505272QA (en) | 2013-01-08 | 2014-01-08 | Age-related macular degeneration treatment |
| SG10201705518SA SG10201705518SA (en) | 2013-01-08 | 2014-01-08 | Age-Related Macular Degeneration Treatment |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201705518SA SG10201705518SA (en) | 2013-01-08 | 2014-01-08 | Age-Related Macular Degeneration Treatment |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US10000753B2 (en) |
| EP (1) | EP2943571A4 (en) |
| JP (1) | JP2016507514A (en) |
| KR (1) | KR20150103280A (en) |
| CN (1) | CN105143450A (en) |
| AU (1) | AU2014205036A1 (en) |
| CA (1) | CA2897342A1 (en) |
| HK (1) | HK1218656A1 (en) |
| IL (1) | IL239836A0 (en) |
| MX (1) | MX2015008697A (en) |
| RU (1) | RU2015133252A (en) |
| SG (2) | SG11201505272QA (en) |
| WO (1) | WO2014107763A1 (en) |
Families Citing this family (50)
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|---|---|---|---|---|
| US20160251410A1 (en) | 2013-09-03 | 2016-09-01 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Compositions and methods for expressing recombinant polypeptides |
| SG11201604692UA (en) * | 2013-12-12 | 2016-07-28 | Alnylam Pharmaceuticals Inc | Complement component irna compositions and methods of use thereof |
| IL234638A0 (en) | 2014-09-14 | 2014-12-02 | Yeda Res & Dev | Nmda receptor antagonists for treating gaucher disease |
| KR20230145206A (en) | 2014-11-14 | 2023-10-17 | 보이저 테라퓨틱스, 인크. | Modulatory polynucleotides |
| MX2017006216A (en) | 2014-11-14 | 2018-08-29 | Voyager Therapeutics Inc | Compositions and methods of treating amyotrophic lateral sclerosis (als). |
| WO2016157175A1 (en) | 2015-03-27 | 2016-10-06 | Yeda Research And Development Co. Ltd. | Methods of treating motor neuron diseases |
| EP3294280A1 (en) | 2015-05-11 | 2018-03-21 | Yeda Research and Development Co., Ltd. | Citrin inhibitors for the treatment of cancer |
| AU2016291817A1 (en) | 2015-07-16 | 2018-02-22 | Biolinerx Ltd. | Compositions and methods for treating cancer |
| US11839195B2 (en) | 2016-01-21 | 2023-12-12 | The State Of Israel, Ministry Of Agriculture & Rural Development, Agricultural Research Organization (Aro) (Volcani Center) | Parthenocarpic tomato plants with loss of function mutation in an AGL6 gene and methods of producing same |
| WO2017138008A2 (en) | 2016-02-14 | 2017-08-17 | Yeda Research And Development Co. Ltd. | Methods of modulating protein exocytosis and uses of same in therapy |
| CN115951066A (en) * | 2016-02-29 | 2023-04-11 | 麦恩泰科特有限公司 | Predictive markers useful for the treatment of wet age-related macular degeneration |
| KR102652994B1 (en) | 2016-05-18 | 2024-04-01 | 보이저 테라퓨틱스, 인크. | Modulatory polynucleotides |
| JP7220080B2 (en) | 2016-05-18 | 2023-02-09 | ボイジャー セラピューティクス インコーポレイテッド | Compositions and methods for treating Huntington's disease |
| IL247368A0 (en) | 2016-08-18 | 2016-11-30 | Yeda Res & Dev | Diagnostic and therapeutic uses of exosomes |
| EP3555294A4 (en) * | 2016-12-14 | 2020-08-26 | Benitec Biopharma Limited | REAGENTS FOR TREATMENT OF OKULOPHARYNGEAL MUSCLE DYSTROPHY (OPMD) AND USES THEREOF |
| WO2018117253A1 (en) * | 2016-12-23 | 2018-06-28 | 協和発酵キリン株式会社 | Nucleic acid inhibiting expression of complement factor b |
| WO2018141025A1 (en) * | 2017-02-03 | 2018-08-09 | Benitec Biopharma Limited | Reagents for treatment of ocular diseases and conditions associated with neovascularisation and use thereof |
| AU2018261790B2 (en) | 2017-05-05 | 2024-10-03 | Voyager Therapeutics, Inc. | Compositions and methods of treating amyotrophic lateral sclerosis (ALS) |
| SG11201909868YA (en) | 2017-05-05 | 2019-11-28 | Voyager Therapeutics Inc | Compositions and methods of treating huntington's disease |
| IL252151A0 (en) | 2017-05-07 | 2017-07-31 | Fainzilber Michael | Methods of treating psychiatric stress disorders |
| WO2019005926A1 (en) * | 2017-06-27 | 2019-01-03 | Massachusetts Eye And Ear Infirmary | Aav-crispr/cas9 genome editing of vegfr2 for treating ocular diseases |
| IL253642A0 (en) | 2017-07-24 | 2017-09-28 | Seger Rony | Combination therapy for the treatment of cancer |
| MX2020002872A (en) * | 2017-09-15 | 2020-10-05 | Commw Scient Ind Res Org | RNA MOLECULES. |
| US11555199B2 (en) | 2017-09-19 | 2023-01-17 | Tropic Biosciences UK Limited | Modifying the specificity of plant non-coding RNA molecules for silencing gene expression |
| US11701391B2 (en) | 2017-10-24 | 2023-07-18 | Dalia ELANI | Methods of treating an ischemic disease |
| AU2018360697A1 (en) | 2017-11-01 | 2020-05-14 | Alnylam Pharmaceuticals, Inc. | Complement component C3 iRNA compositions and methods of use thereof |
| IL255664A0 (en) | 2017-11-14 | 2017-12-31 | Shachar Idit | Hematopoietic stem cells with improved properties |
| IL262658A (en) | 2018-10-28 | 2020-04-30 | Memorial Sloan Kettering Cancer Center | Prevention of age related clonal hematopoiesis and diseases associated therewith |
| GB201903519D0 (en) | 2019-03-14 | 2019-05-01 | Tropic Biosciences Uk Ltd | Introducing silencing activity to dysfunctional rna molecules and modifying their specificity against a gene of interest |
| GB201903520D0 (en) | 2019-03-14 | 2019-05-01 | Tropic Biosciences Uk Ltd | Modifying the specificity of non-coding rna molecules for silencing genes in eukaryotic cells |
| GB201903521D0 (en) | 2019-03-14 | 2019-05-01 | Tropic Biosciences Uk Ltd | No title |
| IL268111A (en) | 2019-07-16 | 2021-01-31 | Fainzilber Michael | Methods of treating pain |
| WO2021050744A2 (en) * | 2019-09-10 | 2021-03-18 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Treatment methods for eye disorders |
| AU2020369515A1 (en) | 2019-10-22 | 2022-04-21 | Alnylam Pharmaceuticals, Inc. | Complement component C3 iRNA compositions and methods of use thereof |
| IL270306A (en) | 2019-10-30 | 2021-05-31 | Yeda Res & Dev | Prevention and treatment of pre-myeloid and myeloid malignancies |
| EP4096647A1 (en) | 2020-01-30 | 2022-12-07 | Yeda Research and Development Co. Ltd | Treating acute liver disease with tlr-mik inhibitors |
| WO2022079719A1 (en) | 2020-10-15 | 2022-04-21 | Yeda Research And Development Co. Ltd. | Method of treating myeloid malignancies |
| WO2022130388A2 (en) | 2020-12-18 | 2022-06-23 | Yeda Research And Development Co. Ltd. | Compositions for use in the treatment of chd2 haploinsufficiency and methods of identifying same |
| KR20230126725A (en) | 2020-12-28 | 2023-08-30 | 1이 테라퓨틱스 엘티디. | P21 mRNA target site for silencing |
| KR20230133859A (en) | 2020-12-28 | 2023-09-19 | 1이 테라퓨틱스 엘티디. | p21 mRNA targeting DNAzyme |
| GB202103256D0 (en) | 2021-03-09 | 2021-04-21 | Tropic Biosciences Uk Ltd | Method for silencing genes |
| US20240316006A1 (en) | 2021-05-10 | 2024-09-26 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Pharmaceutical compositions for treating neurological conditions |
| WO2023018523A2 (en) * | 2021-07-17 | 2023-02-16 | Sirnaomics, Inc. | Products and compositions |
| WO2023031359A1 (en) * | 2021-09-02 | 2023-03-09 | Silence Therapeutics Gmbh | Nucleic acids for inhibiting expression of complement factor b (cfb) in a cell |
| WO2023062636A1 (en) | 2021-10-14 | 2023-04-20 | Weedout Ltd. | Methods of weed control |
| EP4423273A1 (en) | 2021-10-29 | 2024-09-04 | Alnylam Pharmaceuticals, Inc. | Complement factor b (cfb) irna compositions and methods of use thereof |
| KR20240107360A (en) * | 2021-11-24 | 2024-07-09 | 아다르엑스 파마슈티컬스, 인크. | Complement factor B-modulating compositions and methods of use thereof |
| CN120898000A (en) | 2023-01-13 | 2025-11-04 | 拉维洛克治疗有限责任公司 | New polynucleotides, cells and methods |
| KR20250159727A (en) | 2023-03-21 | 2025-11-11 | 애로우헤드 파마슈티컬스 인코포레이티드 | RNAi agents for inhibiting the expression of complement factor B (CFB), pharmaceutical compositions thereof and methods of use thereof |
| WO2026009227A1 (en) | 2024-07-04 | 2026-01-08 | Yeda Research And Development Co. Ltd. | Compositions for downregulating zeb2 in macrophages and uses thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US7517864B2 (en) | 2001-05-18 | 2009-04-14 | Sirna Therapeutics, Inc. | RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA) |
| US7148342B2 (en) | 2002-07-24 | 2006-12-12 | The Trustees Of The University Of Pennyslvania | Compositions and methods for sirna inhibition of angiogenesis |
| US7309487B2 (en) * | 2004-02-09 | 2007-12-18 | George Inana | Methods and compositions for detecting and treating retinal diseases |
| KR101337579B1 (en) * | 2004-03-05 | 2013-12-06 | 베니텍 리미티드 | MULTIPLE PROMOTER EXPRESSION CASSETTES FOR SIMULTANEOUS DELIVERY OF RNAi AGENTS |
| EP2636739B1 (en) * | 2004-03-12 | 2014-12-10 | Alnylam Pharmaceuticals Inc. | iRNA agents targeting VEGF |
| US8282921B2 (en) * | 2004-08-02 | 2012-10-09 | Paul Glidden | tRNA synthetase fragments |
| NZ560936A (en) * | 2005-02-03 | 2010-04-30 | Benitec Inc | RNAI expression constructs |
| AU2006239169A1 (en) * | 2005-04-28 | 2006-11-02 | Benitec, Limited. | Multiple-RNAi expression cassettes for simultaneous delivery of RNAi agents related to heterozygotic expression patterns |
| JP5078904B2 (en) * | 2005-11-21 | 2012-11-21 | ジヨンソン・アンド・ジヨンソン・リサーチ・ピーテイワイ・リミテツド | Multi-targeting interfering RNAs and methods for their use and design |
| GB0608838D0 (en) * | 2006-05-04 | 2006-06-14 | Novartis Ag | Organic compounds |
| CN101674853B (en) * | 2007-05-04 | 2013-03-27 | 玛瑞纳生物技术有限公司 | Amino acid lipids and uses thereof |
| WO2008154482A2 (en) * | 2007-06-08 | 2008-12-18 | Sirnaomics, Inc. | Sirna compositions and methods of use in treatment of ocular diseases |
| US8283331B2 (en) * | 2007-10-09 | 2012-10-09 | Children's Medical Center Corporation | Methods to regulate miRNA processing by targeting Lin-28 |
| CA2745832A1 (en) * | 2008-12-04 | 2010-06-10 | Opko Ophthalmics, Llc | Compositions and methods for selective inhibition of pro-angiogenic vegf isoforms |
| EP2598639A4 (en) * | 2010-07-28 | 2014-08-13 | Alcon Res Ltd | VEGFA TARGETING SIARN AND IN VIVO TREATMENT METHODS |
| US9220716B2 (en) | 2011-07-26 | 2015-12-29 | Children's Medical Center Corporation | Methods and compositions for the treatment of proliferative vascular disorders |
| US9518260B2 (en) * | 2012-02-29 | 2016-12-13 | Benitec Biopharma Limited | Pain treatment |
-
2014
- 2014-01-08 SG SG11201505272QA patent/SG11201505272QA/en unknown
- 2014-01-08 HK HK16106608.3A patent/HK1218656A1/en unknown
- 2014-01-08 WO PCT/AU2014/000007 patent/WO2014107763A1/en not_active Ceased
- 2014-01-08 KR KR1020157021273A patent/KR20150103280A/en not_active Withdrawn
- 2014-01-08 MX MX2015008697A patent/MX2015008697A/en unknown
- 2014-01-08 CA CA2897342A patent/CA2897342A1/en not_active Abandoned
- 2014-01-08 SG SG10201705518SA patent/SG10201705518SA/en unknown
- 2014-01-08 EP EP14737958.0A patent/EP2943571A4/en not_active Withdrawn
- 2014-01-08 CN CN201480010251.6A patent/CN105143450A/en active Pending
- 2014-01-08 RU RU2015133252A patent/RU2015133252A/en not_active Application Discontinuation
- 2014-01-08 US US14/759,401 patent/US10000753B2/en active Active
- 2014-01-08 AU AU2014205036A patent/AU2014205036A1/en not_active Abandoned
- 2014-01-08 JP JP2015551090A patent/JP2016507514A/en not_active Ceased
-
2015
- 2015-07-08 IL IL239836A patent/IL239836A0/en unknown
-
2018
- 2018-04-27 US US15/964,584 patent/US20180320180A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL239836A0 (en) | 2015-08-31 |
| US20180320180A1 (en) | 2018-11-08 |
| EP2943571A4 (en) | 2016-11-30 |
| JP2016507514A (en) | 2016-03-10 |
| US10000753B2 (en) | 2018-06-19 |
| WO2014107763A1 (en) | 2014-07-17 |
| MX2015008697A (en) | 2016-08-04 |
| AU2014205036A1 (en) | 2015-07-30 |
| EP2943571A1 (en) | 2015-11-18 |
| CA2897342A1 (en) | 2014-07-17 |
| CN105143450A (en) | 2015-12-09 |
| HK1218656A1 (en) | 2017-03-03 |
| KR20150103280A (en) | 2015-09-09 |
| SG10201705518SA (en) | 2017-08-30 |
| US20160145611A1 (en) | 2016-05-26 |
| RU2015133252A (en) | 2017-02-10 |
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