SG11201500980WA - Clostridium difficile polypeptides as vaccine - Google Patents

Clostridium difficile polypeptides as vaccine

Info

Publication number: SG11201500980WA
Authority: SG; Singapore
Prior art keywords: vaccine; clostridium difficile; polypeptides; difficile polypeptides; clostridium
Prior art date: 2012-09-19

Application number

SG11201500980WA

Inventor

Cesira Galeotti

Rosanna Leuzzi

Mariagrazia Pizza

Maria Scarselli

Meera Unnikrishnan

Manuele Martinelli

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2012-09-19

Filing date

2013-09-19

Publication date

2015-04-29

2012-09-19 Priority claimed from GB201216749A external-priority patent/GB201216749D0/en

2012-09-19 Priority claimed from GB201216748A external-priority patent/GB201216748D0/en

2013-09-19 Application filed by Novartis Ag filed Critical Novartis Ag

2015-04-29 Publication of SG11201500980WA publication Critical patent/SG11201500980WA/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Clostridium (G)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
- C07K16/1282—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Clostridium (G)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
Mycology (AREA)
Epidemiology (AREA)
Gastroenterology & Hepatology (AREA)
Pulmonology (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

SG11201500980WA 2012-09-19 2013-09-19 Clostridium difficile polypeptides as vaccine SG11201500980WA (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB201216749A GB201216749D0 (en)	2012-09-19	2012-09-19	Antigen combinations
GB201216748A GB201216748D0 (en)	2012-09-19	2012-09-19	Methods of treatment
PCT/IB2013/058673 WO2014045226A1 (en)	2012-09-19	2013-09-19	Clostridium difficile polypeptides as vaccine

Publications (1)

Publication Number	Publication Date
SG11201500980WA true SG11201500980WA (en)	2015-04-29

Family

ID=49725168

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG11201500980WA SG11201500980WA (en)	2012-09-19	2013-09-19	Clostridium difficile polypeptides as vaccine

Country Status (13)

Country	Link
US (1)	US9932374B2 (en)
EP (1)	EP2897637A1 (en)
JP (1)	JP2015529677A (en)
KR (1)	KR20150056540A (en)
CN (1)	CN104582722A (en)
AU (1)	AU2013319821A1 (en)
BR (1)	BR112015004629A2 (en)
CA (1)	CA2882620A1 (en)
IL (1)	IL237172A0 (en)
MX (1)	MX2015002485A (en)
RU (1)	RU2015106916A (en)
SG (1)	SG11201500980WA (en)
WO (1)	WO2014045226A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2969952T3 (en)	2011-04-22	2024-05-23	Wyeth Llc	Compositions related to a mutant Clostridium difficile toxin and their procedures
BR122016023101B1 (en)	2012-10-21	2022-03-22	Pfizer Inc	Polypeptide, immunogenic composition comprising it, as well as recombinant cell derived from Clostridium difficile
GB2525177A (en) *	2014-04-14	2015-10-21	New Royal Holloway & Bedford	Vaccine
US10533036B2 (en)	2015-02-19	2020-01-14	Immune Biosolutions Inc	Clostridium difficile toxins a and/or B antigen and epitope antibody, and pharmaceutical uses thereof
US10738338B2 (en)	2016-10-18	2020-08-11	The Research Foundation for the State University	Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
CA3102353A1 (en)	2018-06-19	2019-12-26	Glaxosmithkline Biologicals Sa	Immunogenic composition
GB202205833D0 (en)	2022-04-21	2022-06-08	Glaxosmithkline Biologicals Sa	Bacteriophage

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998059053A1 (en) *	1997-06-20	1998-12-30	Queen Mary & Westfield College	Immonogenic fragments of toxin a of clostridium difficile
WO2001070955A2 (en) *	2000-03-21	2001-09-27	Elitra Pharmaceuticals, Inc.	Identification of essential genes in prokaryotes
AU2001264488A1 (en)	2000-06-07	2001-12-17	Smittskyddsinstitutet	Gene expression cassette and its use
WO2002077183A2 (en)	2001-03-21	2002-10-03	Elitra Pharmaceuticals, Inc.	Identification of essential genes in microorganisms
US20040029129A1 (en) *	2001-10-25	2004-02-12	Liangsu Wang	Identification of essential genes in microorganisms
US7226597B2 (en) *	2002-06-17	2007-06-05	The Board Of Regents Of The University Of Oklahoma	Mutants of Clostridium difficile toxin B and methods of use
US8883172B2 (en) *	2007-06-14	2014-11-11	The Secretary Of State For Health	Chemically modified peptides with improved immunogenicity
EP2271366A4 (en) *	2008-02-28	2012-06-20	3M Innovative Properties Co	Antibodies to clostridium difficile spores and uses thereof
US10046040B2 (en) *	2009-11-16	2018-08-14	University Of Maryland, Baltimore	Multivalent live vector vaccine against Clostridium difficile-associated disease
AU2010325992A1 (en)	2009-12-02	2012-05-31	Tufts University	Atoxic recombinant holotoxins of Clostridium difficile as immunogens
BR112014013876A2 (en) *	2011-12-08	2019-09-24	Novartis Ag	clostridium difficile toxin-based vaccine

2013
- 2013-09-19 EP EP13802107.6A patent/EP2897637A1/en active Pending
- 2013-09-19 AU AU2013319821A patent/AU2013319821A1/en not_active Abandoned
- 2013-09-19 MX MX2015002485A patent/MX2015002485A/en unknown
- 2013-09-19 JP JP2015531683A patent/JP2015529677A/en active Pending
- 2013-09-19 WO PCT/IB2013/058673 patent/WO2014045226A1/en active Application Filing
- 2013-09-19 KR KR1020157005022A patent/KR20150056540A/en not_active Withdrawn
- 2013-09-19 BR BR112015004629A patent/BR112015004629A2/en not_active IP Right Cessation
- 2013-09-19 CN CN201380045505.3A patent/CN104582722A/en active Pending
- 2013-09-19 SG SG11201500980WA patent/SG11201500980WA/en unknown
- 2013-09-19 US US14/425,037 patent/US9932374B2/en active Active
- 2013-09-19 RU RU2015106916A patent/RU2015106916A/en not_active Application Discontinuation
- 2013-09-19 CA CA2882620A patent/CA2882620A1/en active Pending
2015
- 2015-02-10 IL IL237172A patent/IL237172A0/en unknown

Also Published As

Publication number	Publication date
MX2015002485A (en)	2015-06-05
BR112015004629A2 (en)	2017-11-21
US9932374B2 (en)	2018-04-03
CN104582722A (en)	2015-04-29
KR20150056540A (en)	2015-05-26
IL237172A0 (en)	2015-04-30
AU2013319821A1 (en)	2015-02-26
JP2015529677A (en)	2015-10-08
EP2897637A1 (en)	2015-07-29
US20150315248A1 (en)	2015-11-05
CA2882620A1 (en)	2014-03-27
RU2015106916A (en)	2016-11-10
WO2014045226A1 (en)	2014-03-27

Publication	Publication Date	Title
IL291571A (en)	2022-05-01	Cx3cr1-binding polypeptides
EP2807186A4 (en)	2016-01-27	Vaccines against clostridium difficile comprising recombinant toxins
GB201218427D0 (en)	2012-11-28	Blender
EP2857033A4 (en)	2016-03-30	Skin-permeating peptide
PL2647387T3 (en)	2016-09-30	Vaccine Composition
GB201220474D0 (en)	2012-12-26	Polypeptides
GB201223386D0 (en)	2013-02-06	Vaccine
SG11201406301TA (en)	2014-11-27	Clostridium difficile antigens
IL232957A0 (en)	2014-07-31	Clostridium difficile toxin-based vaccine
EP2804194A4 (en)	2015-09-02	Limit switch
EP2925362A4 (en)	2016-07-20	Antibodies against clostridium difficile
GB201217488D0 (en)	2012-11-14	Blender
SG11201500980WA (en)	2015-04-29	Clostridium difficile polypeptides as vaccine
ZA201503127B (en)	2016-10-26	Peptides
GB201200555D0 (en)	2012-02-29	Peptide
GB201204868D0 (en)	2012-05-02	Peptides
IL237571A0 (en)	2015-04-30	Tiotropium preparations
GB201223114D0 (en)	2013-02-06	Novel peptide
GB201210226D0 (en)	2012-07-25	Vaccine
GB201202090D0 (en)	2012-03-21	Vaccine
DK2846829T3 (en)	2021-12-06	Vaccine combinations
PT2891663T (en)	2018-03-20	Psf1-derived peptides
IL231661A0 (en)	2014-05-28	Clostridium difficile antibodies
GB201121149D0 (en)	2012-01-18	Clostridium difficile toxin-based vaccine
GB201220328D0 (en)	2012-12-26	Peptides