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SG11201500145TA - Crystalline forms of dihydropyrimidine derivatives - Google Patents

Crystalline forms of dihydropyrimidine derivatives

Info

Publication number
SG11201500145TA
SG11201500145TA SG11201500145TA SG11201500145TA SG11201500145TA SG 11201500145T A SG11201500145T A SG 11201500145TA SG 11201500145T A SG11201500145T A SG 11201500145TA SG 11201500145T A SG11201500145T A SG 11201500145TA SG 11201500145T A SG11201500145T A SG 11201500145TA
Authority
SG
Singapore
Prior art keywords
crystalline forms
dihydropyrimidine derivatives
dihydropyrimidine
derivatives
crystalline
Prior art date
Application number
SG11201500145TA
Inventor
Yingjun Zhang
Qingyun Ren
Xinchang Liu
Chaolei Wang
Tianming Wang
Siegfried Goldmann
Original Assignee
Sunshine Lake Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sunshine Lake Pharma Co Ltd filed Critical Sunshine Lake Pharma Co Ltd
Publication of SG11201500145TA publication Critical patent/SG11201500145TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG11201500145TA 2012-09-27 2013-09-27 Crystalline forms of dihydropyrimidine derivatives SG11201500145TA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201210369019 2012-09-27
CN201310117076 2013-04-04
PCT/CN2013/084383 WO2014048355A1 (en) 2012-09-27 2013-09-27 Crystalline forms of dihydropyrimidine derivatives

Publications (1)

Publication Number Publication Date
SG11201500145TA true SG11201500145TA (en) 2015-02-27

Family

ID=50355923

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201500145TA SG11201500145TA (en) 2012-09-27 2013-09-27 Crystalline forms of dihydropyrimidine derivatives

Country Status (21)

Country Link
US (1) US9403814B2 (en)
EP (1) EP2900664B1 (en)
JP (1) JP6310923B2 (en)
KR (1) KR20150060610A (en)
CN (3) CN103724339B (en)
AU (1) AU2013324779B2 (en)
BR (1) BR112015002979B8 (en)
CA (1) CA2881260C (en)
DK (1) DK2900664T3 (en)
ES (1) ES2660642T3 (en)
HK (1) HK1207081A1 (en)
HU (1) HUE037285T2 (en)
MX (1) MX362829B (en)
MY (1) MY171497A (en)
PL (1) PL2900664T3 (en)
PT (1) PT2900664T (en)
RU (1) RU2646599C2 (en)
SG (1) SG11201500145TA (en)
TW (1) TWI561520B (en)
WO (1) WO2014048355A1 (en)
ZA (1) ZA201500290B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20150054795A (en) 2012-09-10 2015-05-20 에프. 호프만-라 로슈 아게 6-amino acid heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
JP6523566B2 (en) * 2015-11-04 2019-06-05 チールー ファーマシューティカル カンパニー、リミテッド Crystal form of dihydropyrido ring compound, production method and intermediate
CN107400125B (en) * 2016-05-19 2020-02-11 广东东阳光药业有限公司 Crystal form, salt and compound of dihydropyrimidine derivative and application thereof in medicines
CN107722109B (en) * 2016-08-11 2020-12-18 广东东阳光药业有限公司 Crystalline forms as hepatitis c virus inhibitors
US9856232B1 (en) * 2017-06-20 2018-01-02 King Saud University Dihydropyrimidinone derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR043880A1 (en) * 2003-04-22 2005-08-17 Solvay Pharm Gmbh ACID MESILATE 4- (4.TRANS-HYDROXICICLOHEXIL) AMINO-2-PHENYL-7H-PIRROLO (2,3-D) PYRIMIDINE AND ITS POLYMORPHAS FORMS
CN101328169B (en) * 2007-06-18 2011-05-25 张中能 Diethylcarbamyl-substituted thiazole dihydropyrimidine
WO2008154818A1 (en) 2007-06-18 2008-12-24 Zhang, Zhongneng Fluorophenyl-substituted thiazolyl dihydropyrimidines
CN101328168B (en) 2007-06-18 2011-09-07 张中能 Diethylcarbamyl-substituted thiazole dihydropyrimidine
PL2159224T3 (en) 2007-06-18 2012-12-31 Ruyuan Wei Xiang Tech Co Ltd Bromo-phenyl substituted thiazolyl dihydropyrimidines
WO2010069147A1 (en) * 2008-12-17 2010-06-24 张中能 Dihydropyrimidine derivatives, compositions thereof and their use
CN101744823B (en) * 2008-12-17 2013-06-19 广东东阳光药业有限公司 Solid dispersion of dihydropyrimidine compounds and preparation thereof for medical purpose

Also Published As

Publication number Publication date
EP2900664B1 (en) 2017-12-13
BR112015002979A2 (en) 2017-07-04
US9403814B2 (en) 2016-08-02
RU2015114085A (en) 2016-11-20
WO2014048355A1 (en) 2014-04-03
CA2881260A1 (en) 2014-04-03
BR112015002979B1 (en) 2020-12-22
PT2900664T (en) 2018-03-02
CN104945394A (en) 2015-09-30
MY171497A (en) 2019-10-15
JP6310923B2 (en) 2018-04-11
HK1207081A1 (en) 2016-01-22
CA2881260C (en) 2020-10-27
CN104945394B (en) 2017-12-05
CN103724339B (en) 2015-10-14
MX2015004115A (en) 2016-01-20
PL2900664T3 (en) 2018-06-29
US20150239877A1 (en) 2015-08-27
EP2900664A1 (en) 2015-08-05
ES2660642T3 (en) 2018-03-23
BR112015002979B8 (en) 2022-03-03
EP2900664A4 (en) 2016-03-09
TW201412732A (en) 2014-04-01
TWI561520B (en) 2016-12-11
KR20150060610A (en) 2015-06-03
JP2015531354A (en) 2015-11-02
MX362829B (en) 2019-02-14
RU2646599C2 (en) 2018-03-06
CN103694234A (en) 2014-04-02
AU2013324779B2 (en) 2015-10-08
ZA201500290B (en) 2016-10-26
AU2013324779A1 (en) 2015-02-05
CN103724339A (en) 2014-04-16
DK2900664T3 (en) 2018-02-05
HUE037285T2 (en) 2018-08-28

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