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SG11201407110QA - Novel dosage form and formulation of abediterol - Google Patents

Novel dosage form and formulation of abediterol

Info

Publication number
SG11201407110QA
SG11201407110QA SG11201407110QA SG11201407110QA SG11201407110QA SG 11201407110Q A SG11201407110Q A SG 11201407110QA SG 11201407110Q A SG11201407110Q A SG 11201407110QA SG 11201407110Q A SG11201407110Q A SG 11201407110QA SG 11201407110Q A SG11201407110Q A SG 11201407110QA
Authority
SG
Singapore
Prior art keywords
international
barcelona
abediterol
llobregat
laurea
Prior art date
Application number
SG11201407110QA
Inventor
Ruiz Sandrine Allain
Nunez Beatriz Seoane
Miquel Serra Gonzalo De
Original Assignee
Almirall Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46317311&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201407110Q(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Almirall Sa filed Critical Almirall Sa
Publication of SG11201407110QA publication Critical patent/SG11201407110QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/47042-Quinolinones, e.g. carbostyril
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

(12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 5 December 2013 (05.12.2013) WIPOIPCT (10) International Publication Number WO 2013/178742 A1 (51) International Patent Classification: A61K 9/14 (2006.01) A61P11/08 (2006.01) A61K31/4706 (2006.01) A61P11/06 (2006.01) A61K9/00 (2006.01) (21) International Application Number: (22) International Filing Date: (25) Filing Language: (26) Publication Language: PCT/EP2013/061181 30 May 2013 (30.05.2013) English (30) Priority Data: 12382221.5 61/660,003 31 May 2012 (31.05.2012) 15 June 2012 (15.06.2012) English EP US (71) Applicant: ALMIRALL, S.A. [ES/ES]; Ronda del Gener­ al Mitre 151, E-08022 Barcelona (ES). (72) Inventors: ALLAIN RUIZ, Sandrine; C/O Laurea Miro 408-410, Sant Feliu de Llobregat, E-08980 Barcelona (ES). SEOANE NUNEZ, Beatriz; C/O Laurea Miro 408- 410, Sant Feliu de Llobregat, E-08980 Barcelona (ES). DE MIQUEL SERRA, Gonzalo; C/O Laurea Miro 408-410, Sant Feliu de Llobregat, E-08980 Barcelona (ES). (74) Agent: SRINIVASAN, Ravi Chandran; 14 South Square, Gray's Inn, London Greater London WC1R 5JJ (GB). (81) Designated States (unless otherwise indicated, for every kind of national protection available)'. AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available)'. ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: — with international search report (Art. 21(3)) CJ •t l> 00 l> i-H ^ (54) Title: NOVEL DOSAGE FORM AND FORMULATION OF ABEDITEROL 5 (57) Abstract: The present invention provides pharmaceutical a composition in the form of a dry powder for inhalation comprising C^l abediterol or a pharmaceutically acceptable salt in admixture with pharmaceutically acceptable carrier, a providing upon inhalation a dose equivalent to a metered nominal dose of about 1.25 or about 2.5 micrograms of free base abediterol administered with the Gen - (5T uair® inhaler. The present invention also provides said pharmaceutical composition for use in the treatment of respiratory disease 5- such as asthma and chronic obstructive pulmonary disease COPD.
SG11201407110QA 2012-05-31 2013-05-30 Novel dosage form and formulation of abediterol SG11201407110QA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12382221.5A EP2668941A1 (en) 2012-05-31 2012-05-31 Novel dosage form and formulation of abediterol
US201261660003P 2012-06-15 2012-06-15
PCT/EP2013/061181 WO2013178742A1 (en) 2012-05-31 2013-05-30 Novel dosage form and formulation of abediterol

Publications (1)

Publication Number Publication Date
SG11201407110QA true SG11201407110QA (en) 2014-12-30

Family

ID=46317311

Family Applications (3)

Application Number Title Priority Date Filing Date
SG11201407110QA SG11201407110QA (en) 2012-05-31 2013-05-30 Novel dosage form and formulation of abediterol
SG10201913424SA SG10201913424SA (en) 2012-05-31 2013-05-30 Novel dosage form and formulation of abediterol
SG10201609119VA SG10201609119VA (en) 2012-05-31 2013-05-30 Novel dosage form and formulation of abediterol

Family Applications After (2)

Application Number Title Priority Date Filing Date
SG10201913424SA SG10201913424SA (en) 2012-05-31 2013-05-30 Novel dosage form and formulation of abediterol
SG10201609119VA SG10201609119VA (en) 2012-05-31 2013-05-30 Novel dosage form and formulation of abediterol

Country Status (29)

Country Link
US (2) US20150140099A1 (en)
EP (2) EP2668941A1 (en)
JP (1) JP6272836B2 (en)
KR (2) KR20180104197A (en)
CN (1) CN104394852A (en)
AR (1) AR091233A1 (en)
AU (1) AU2013269565B2 (en)
BR (1) BR112014029735A2 (en)
CA (1) CA2871358C (en)
CL (1) CL2014003286A1 (en)
CO (1) CO7141434A2 (en)
CR (1) CR20140540A (en)
DO (1) DOP2014000271A (en)
EA (1) EA201401354A1 (en)
EC (1) ECSP14028814A (en)
HK (1) HK1203149A1 (en)
IL (1) IL235831B (en)
IN (1) IN2014DN08672A (en)
MX (1) MX2014014350A (en)
MY (1) MY184654A (en)
NI (1) NI201400139A (en)
NZ (1) NZ701261A (en)
PE (1) PE20150171A1 (en)
PH (1) PH12014502662A1 (en)
SG (3) SG11201407110QA (en)
TW (1) TWI610690B (en)
UY (1) UY34838A (en)
WO (1) WO2013178742A1 (en)
ZA (1) ZA201407405B (en)

Families Citing this family (10)

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EP2641900A1 (en) 2012-03-20 2013-09-25 Almirall, S.A. Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor.
WO2014007781A2 (en) * 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions
AU2015275933A1 (en) * 2014-06-18 2017-02-02 Cipla Limited Pharmaceutical composition comprising a beta-2-agonist and anticholinergic agent
WO2019142214A1 (en) * 2018-01-19 2019-07-25 Cipla Limited Pharmaceutical composition comprising tiotropium for inhalation
JP2021524323A (en) 2018-05-22 2021-09-13 シー・アール・バード・インコーポレーテッドC R Bard Incorporated Catheter insertion system and how to use it
CN112566550B (en) 2018-08-10 2024-10-22 C·R·巴德股份有限公司 Automatic urine output measuring system and method thereof
US12083261B2 (en) 2020-06-05 2024-09-10 C. R. Bard, Inc. Automated fluid output monitoring
US12055249B2 (en) 2020-07-21 2024-08-06 C. R. Bard, Inc. Automatic fluid flow system with retractable connection
US11931151B2 (en) 2020-12-22 2024-03-19 C. R. Bard, Inc. Automated urinary output measuring system
US12246146B2 (en) 2020-12-23 2025-03-11 C. R. Bard, Inc. Automated weight based fluid output monitoring system

Family Cites Families (33)

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IT7920688V0 (en) 1979-02-05 1979-02-05 Chiesi Paolo Parma INHALER FOR PULVERULENT MEDICINAL SUBSTANCES, WITH COMBINED DOSER FUNCTION.
CY1492A (en) 1981-07-08 1990-02-16 Draco Ab Powder inhalator
US4570630A (en) 1983-08-03 1986-02-18 Miles Laboratories, Inc. Medicament inhalation device
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ES2306595B1 (en) * 2007-02-09 2009-09-11 Laboratorios Almirall S.A. NAPADISYLATE SALT OF 5- (2 - ((6- (2,2-DIFLUORO-2-PHENYLETOXI) HEXIL) AMINO) -1-HYDROXYETHYL) -8-HYDROXYCHINOLIN-2 (1H) -ONE AS ADRENERGIC RECEIVER AGONIST BETA2 .
EP2100598A1 (en) * 2008-03-13 2009-09-16 Laboratorios Almirall, S.A. Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
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EP2221297A1 (en) * 2009-02-18 2010-08-25 Almirall, S.A. 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one and its use in the treatment of pulmonary diseases
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Also Published As

Publication number Publication date
NZ701261A (en) 2016-08-26
IL235831B (en) 2020-09-30
SG10201609119VA (en) 2016-12-29
KR20180104197A (en) 2018-09-19
AR091233A1 (en) 2015-01-21
CN104394852A (en) 2015-03-04
US20160303108A1 (en) 2016-10-20
AU2013269565B2 (en) 2017-07-20
AU2013269565A1 (en) 2014-10-30
TW201347789A (en) 2013-12-01
JP2015519356A (en) 2015-07-09
EP2668941A1 (en) 2013-12-04
SG10201913424SA (en) 2020-03-30
DOP2014000271A (en) 2015-02-27
EP2854771A1 (en) 2015-04-08
WO2013178742A1 (en) 2013-12-05
PH12014502662A1 (en) 2015-02-02
CA2871358C (en) 2020-09-29
KR20150018526A (en) 2015-02-23
IN2014DN08672A (en) 2015-05-22
CL2014003286A1 (en) 2015-02-20
UY34838A (en) 2014-03-31
CO7141434A2 (en) 2014-12-12
CR20140540A (en) 2015-01-16
US20150140099A1 (en) 2015-05-21
JP6272836B2 (en) 2018-01-31
EA201401354A1 (en) 2015-05-29
MX2014014350A (en) 2015-03-03
IL235831A0 (en) 2015-01-29
MY184654A (en) 2021-04-14
TWI610690B (en) 2018-01-11
ZA201407405B (en) 2015-11-25
PE20150171A1 (en) 2015-01-31
BR112014029735A2 (en) 2017-06-27
ECSP14028814A (en) 2015-12-31
NI201400139A (en) 2015-12-10
HK1203149A1 (en) 2015-10-23
CA2871358A1 (en) 2013-12-05

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