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SG11201406860SA - Quinazolinedione derivative - Google Patents

Quinazolinedione derivative

Info

Publication number
SG11201406860SA
SG11201406860SA SG11201406860SA SG11201406860SA SG11201406860SA SG 11201406860S A SG11201406860S A SG 11201406860SA SG 11201406860S A SG11201406860S A SG 11201406860SA SG 11201406860S A SG11201406860S A SG 11201406860SA SG 11201406860S A SG11201406860S A SG 11201406860SA
Authority
SG
Singapore
Prior art keywords
quinazolinedione derivative
quinazolinedione
derivative
Prior art date
Application number
SG11201406860SA
Inventor
Takeshi Murata
Hatsuo Kawada
Satoshi Niizuma
Sousuke Hara
Kihito Hada
Hideaki Shimada
Hiroshi Tanaka
Toshiyuki Mio
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of SG11201406860SA publication Critical patent/SG11201406860SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG11201406860SA 2012-04-24 2013-04-24 Quinazolinedione derivative SG11201406860SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012098954 2012-04-24
PCT/JP2013/062006 WO2013161853A1 (en) 2012-04-24 2013-04-24 Quinazolinedione derivative

Publications (1)

Publication Number Publication Date
SG11201406860SA true SG11201406860SA (en) 2014-11-27

Family

ID=49483161

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201406860SA SG11201406860SA (en) 2012-04-24 2013-04-24 Quinazolinedione derivative

Country Status (15)

Country Link
US (1) US9567304B2 (en)
EP (1) EP2842946B1 (en)
JP (1) JP6130828B2 (en)
KR (1) KR20150003849A (en)
CN (1) CN104379568A (en)
AR (1) AR090835A1 (en)
AU (1) AU2013253541A1 (en)
BR (1) BR112014026305A2 (en)
CA (1) CA2871453A1 (en)
HK (1) HK1203943A1 (en)
MX (1) MX2014012992A (en)
RU (1) RU2014146993A (en)
SG (1) SG11201406860SA (en)
TW (1) TW201348213A (en)
WO (1) WO2013161853A1 (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112014026266A2 (en) 2012-04-24 2017-06-27 Chugai Pharmaceutical Co Ltd quinazolidinedione derivative
JP6307088B2 (en) * 2013-10-23 2018-04-04 中外製薬株式会社 Quinazolinone and isoquinolinone derivatives
EP3192791A4 (en) 2014-09-11 2018-03-28 Takeda Pharmaceutical Company Limited Heterocyclic compound
HK1248209A1 (en) 2015-08-31 2018-10-12 东丽株式会社 Urea derivative and use therefor
CN107922320A (en) 2015-08-31 2018-04-17 东丽株式会社 Urea derivative and its purposes
WO2018138050A1 (en) 2017-01-26 2018-08-02 Bayer Aktiengesellschaft Condensed bicyclic heterocyclene derivatives as pest control agents
AU2020229979B2 (en) 2019-02-26 2025-03-06 Bayer Aktiengesellschaft Fused bicyclic heterocycle derivatives as pesticides
CN110218193A (en) * 2019-07-08 2019-09-10 山东大学 3- hydroxyquinazoline -2,4 (1H, 3H)-diketone derivative and the preparation method and application thereof
CN112608282B (en) * 2019-12-20 2022-07-26 山东先达农化股份有限公司 Compound containing quinazolinedione and N-O structure and preparation method and application thereof

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DK570987A (en) 1986-12-01 1988-06-02 Hoffmann La Roche OXADIAZOL, THIADIAZOL AND TRIAZOL COMPOUNDS
JP2751309B2 (en) 1988-02-16 1998-05-18 三菱化学株式会社 Pyrazoles and insecticides, miticides, fungicides containing them as an active ingredient
JPH05255268A (en) 1992-03-17 1993-10-05 Mitsubishi Kasei Corp Pyrazolecarboxamides, insecticide, acaricide and agricultural and horticultural germicide comprising the same as active ingredient
TW225528B (en) 1992-04-03 1994-06-21 Ciba Geigy Ag
JP3488890B2 (en) 1993-11-09 2004-01-19 アグロカネショウ株式会社 3-N-substituted quinazolinone derivatives, process for producing the same, and herbicides containing the compounds
US7125875B2 (en) 1999-04-15 2006-10-24 Bristol-Myers Squibb Company Cyclic protein tyrosine kinase inhibitors
MXPA00006605A (en) 1999-07-02 2004-12-09 Pfizer Bicycliccarbonyl indole compounds as anti-inflammatory/analgesic agents.
FR2831536A1 (en) 2001-10-26 2003-05-02 Aventis Pharma Sa NOVEL BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND NOVEL USE IN PARTICULAR AS KDR INHIBITORS
WO2003053958A1 (en) 2001-12-20 2003-07-03 Celltech R & D Limited Quinazolinedione derivatives
GB0215676D0 (en) 2002-07-05 2002-08-14 Novartis Ag Organic compounds
CA2551529C (en) 2003-12-25 2011-02-01 Nippon Shinyaku Co., Ltd. Amide derivative and medicine
US7511062B2 (en) 2004-05-18 2009-03-31 Schering Corporation Substituted 2-quinolyl-oxazoles useful as PDE4 inhibitors
US7683218B2 (en) 2004-10-08 2010-03-23 Banyu Pharmaceutical Co., Ltd. Method for producing thioether compound
EP1987004A2 (en) 2006-02-16 2008-11-05 Boehringer Ingelheim International GmbH Substituted pyridineamide compounds useful as soluble epoxide hydrolase inhibitors
US20080255161A1 (en) 2007-04-11 2008-10-16 Dmitry Koltun 3-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS
FR2921926B1 (en) 2007-10-03 2009-12-04 Sanofi Aventis QUINAZOLINEDIONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATIONS THEREOF.
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JP2012505881A (en) 2008-10-15 2012-03-08 ギリアード サイエンシーズ, インコーポレイテッド 3-Hydrazolin-4-one derivatives for use as inhibitors of stearoyl-CoA desaturase
WO2010065760A1 (en) 2008-12-04 2010-06-10 Exelixis, Inc. Imidazo [1,2a] pyridine derivatives, their use as s1p1 agonists and methods for their production
MX2012004709A (en) * 2009-10-23 2012-05-23 Novartis Ag Method of treating proliferative disorders and other pathological conditions mediated by bcr-abl, c-kit, ddr1, ddr2 or pdgf-r kinase activity.
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WO2012125521A1 (en) 2011-03-14 2012-09-20 Eternity Bioscience Inc. Quinazolinediones and their use
TWI527800B (en) 2011-04-01 2016-04-01 南京英派藥業有限公司 1-(arylmethyl)quinazoline-2,4(1h,3h)-diones as parp inhibitors and the use thereof
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BR112014026266A2 (en) 2012-04-24 2017-06-27 Chugai Pharmaceutical Co Ltd quinazolidinedione derivative

Also Published As

Publication number Publication date
EP2842946B1 (en) 2016-09-28
CN104379568A (en) 2015-02-25
MX2014012992A (en) 2015-08-14
EP2842946A1 (en) 2015-03-04
AU2013253541A1 (en) 2014-11-20
CA2871453A1 (en) 2013-10-31
JPWO2013161853A1 (en) 2015-12-24
KR20150003849A (en) 2015-01-09
RU2014146993A (en) 2016-06-10
TW201348213A (en) 2013-12-01
JP6130828B2 (en) 2017-05-17
WO2013161853A1 (en) 2013-10-31
HK1203943A1 (en) 2015-11-06
US9567304B2 (en) 2017-02-14
AR090835A1 (en) 2014-12-10
BR112014026305A2 (en) 2017-06-27
US20150141400A1 (en) 2015-05-21
EP2842946A4 (en) 2015-09-09

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