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SG11201400640VA - Process line for the production of freeze-dried particles - Google Patents

Process line for the production of freeze-dried particles

Info

Publication number
SG11201400640VA
SG11201400640VA SG11201400640VA SG11201400640VA SG11201400640VA SG 11201400640V A SG11201400640V A SG 11201400640VA SG 11201400640V A SG11201400640V A SG 11201400640VA SG 11201400640V A SG11201400640V A SG 11201400640VA SG 11201400640V A SG11201400640V A SG 11201400640VA
Authority
SG
Singapore
Prior art keywords
freeze
production
process line
dried particles
dried
Prior art date
Application number
SG11201400640VA
Inventor
Bernhard Luy
Matthias Plitzko
Manfred Struschka
Original Assignee
Sanofi Pasteur Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Sa filed Critical Sanofi Pasteur Sa
Publication of SG11201400640VA publication Critical patent/SG11201400640VA/en

Links

Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26DRYING
    • F26BDRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F26B5/065Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing the product to be freeze-dried being sprayed, dispersed or pulverised

Landscapes

  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Drying Of Solid Materials (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Inorganic Compounds Of Heavy Metals (AREA)
  • Oxygen, Ozone, And Oxides In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
SG11201400640VA 2011-10-05 2012-10-04 Process line for the production of freeze-dried particles SG11201400640VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11008057.9A EP2578974A1 (en) 2011-10-05 2011-10-05 Process line for the production of freeze-dried particles
PCT/EP2012/004168 WO2013050162A1 (en) 2011-10-05 2012-10-04 Process line for the production of freeze-dried particles

Publications (1)

Publication Number Publication Date
SG11201400640VA true SG11201400640VA (en) 2014-06-27

Family

ID=46980888

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201400641QA SG11201400641QA (en) 2011-10-05 2012-10-04 Process line for the production of freeze-dried particles
SG11201400640VA SG11201400640VA (en) 2011-10-05 2012-10-04 Process line for the production of freeze-dried particles

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201400641QA SG11201400641QA (en) 2011-10-05 2012-10-04 Process line for the production of freeze-dried particles

Country Status (25)

Country Link
US (2) US10006706B2 (en)
EP (4) EP2578974A1 (en)
JP (2) JP5766361B2 (en)
KR (2) KR101552804B1 (en)
CN (2) CN103917842B (en)
AU (2) AU2012320848B8 (en)
BR (2) BR112014007862B1 (en)
CA (2) CA2849802C (en)
CO (2) CO6930306A2 (en)
CR (2) CR20140158A (en)
DK (2) DK2766682T3 (en)
EA (2) EA027630B1 (en)
ES (2) ES2608478T3 (en)
HU (2) HUE029973T2 (en)
IL (2) IL231853A0 (en)
IN (2) IN2014CN02440A (en)
MX (2) MX341894B (en)
MY (2) MY151369A (en)
PE (2) PE20142141A1 (en)
PH (2) PH12014500621A1 (en)
PL (2) PL2766682T3 (en)
SG (2) SG11201400641QA (en)
UA (2) UA111859C2 (en)
WO (2) WO2013050162A1 (en)
ZA (1) ZA201401930B (en)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110142885A1 (en) 2009-09-16 2011-06-16 Velico Medical, Inc. Spray-dried human plasma
US20140083628A1 (en) 2012-09-27 2014-03-27 Velico Medical, Inc. Spray drier assembly for automated spray drying
EP2578975A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Rotary drum freeze-dryer
EP2578974A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Process line for the production of freeze-dried particles
EP2578976A1 (en) 2011-10-06 2013-04-10 Sanofi Pasteur Sa Rotary drum for use in a vacuum freeze-dryer
UA111631C2 (en) 2011-10-06 2016-05-25 Санофі Пастер Са HEATING DEVICE FOR ROTOR DRUM LYOPHILE DRYER
CN105452791B (en) 2013-05-29 2017-05-31 基伊埃工程技术股份有限公司 Inline sterilizing freeze-drying is provided and is contained in the method for product in handcart pallet, the system for performing the method and the use to the method
DK3171954T3 (en) * 2014-07-21 2018-08-06 Sanofi Pasteur Sa LIQUID APPLICATION FOR THE GENERATION OF DROPS AND ITS USE FOR PREPARING A VACCINE COMPOSITION
US9561184B2 (en) 2014-09-19 2017-02-07 Velico Medical, Inc. Methods and systems for multi-stage drying of plasma
DE102015105375B4 (en) 2015-01-07 2016-11-03 Richard Süverkrüp Apparatus and method for producing monodisperse frozen drops
US9739532B2 (en) * 2015-02-04 2017-08-22 Steven F. Baugh Botanical freeze drying system and method
ES2760075T3 (en) 2015-06-01 2020-05-13 Ima Life North America Inc Bulk lyophilization using spray freeze and stir dry with heating
RU2615553C1 (en) * 2015-10-15 2017-04-05 Акционерное общество "Военно-промышленная корпорация "Научно-производственное объединение машиностроения" Method and device for continuous dehydrofreezing of liquid products
EP3167877A1 (en) 2015-11-12 2017-05-17 Bayer Pharma Aktiengesellschaft Method for the production of freeze-dried pellets comprising factor viii
CN106705574A (en) * 2015-11-17 2017-05-24 上海东富龙科技股份有限公司 Solid preparation fabrication equipment and method
JP6666535B2 (en) * 2016-01-05 2020-03-18 株式会社あい・あいエナジーアソシエイツ Liquid freeze drying apparatus and freeze drying method
CN105674691B (en) * 2016-04-01 2017-11-21 苏州大学 For collecting the Dual-sealing equipment and its collection method of spray chilling ice hockey particle
US10369077B2 (en) * 2017-05-31 2019-08-06 Adienne Pharma & Biotech Sa Multi chamber flexible bag and methods of using the same
US10507165B2 (en) 2017-05-31 2019-12-17 Adienne Pharma & Biotech Sa Multi chamber flexible bag and methods of using same
DE102017119649A1 (en) 2017-08-28 2019-02-28 Richard Süverkrüp Process for the continuous production of freeze-dried droplets in a closed gas cycle
ES2779023T3 (en) * 2017-10-20 2020-08-13 Martin Christ Gefriertrocknungsanlagen Gmbh Procedure for pressure-based determination of a product parameter in a lyophilizer, lyophilizer, and software product
KR102450460B1 (en) * 2017-12-29 2022-09-30 아주대학교산학협력단 Mass production system of microsphere drug using ultrasonic nebulizer
WO2019175954A1 (en) * 2018-03-13 2019-09-19 株式会社プリス Device for producing dry powder using spray freeze granulation and system for producing dry powder using spray freeze granulation
WO2019235036A1 (en) * 2018-06-08 2019-12-12 株式会社アルバック Freeze vacuum drying device and freeze vacuum drying method
CN112367975A (en) 2018-07-05 2021-02-12 拜耳公司 Method for preparing freeze-dried pellets comprising anti-coagulation factor xia (fxia) antibodies
WO2020161863A1 (en) * 2019-02-07 2020-08-13 株式会社アルバック Vacuum-freeze drying method and vacuum-freeze drying device
US11243029B2 (en) * 2019-04-26 2022-02-08 Purdue Research Foundation Process monitoring and control for lyophilization using a wireless sensor network
CN111207564B (en) * 2019-09-30 2022-01-04 中国科学院上海硅酸盐研究所 A freeze drying system and method
CN114786497A (en) * 2019-12-09 2022-07-22 雀巢产品有限公司 Beverage paste
JP6777350B1 (en) 2020-05-18 2020-10-28 株式会社エムアイアイ Vacuum freeze-drying equipment and vacuum freeze-drying method
TWI860477B (en) 2020-05-18 2024-11-01 日商Mii股份有限公司 Vacuum freeze drying device and vacuum freeze drying method
US20230168034A1 (en) * 2020-08-07 2023-06-01 Ulvac, Inc. Vacuum freeze-drying method, injection nozzle for a vacuum freeze-drying apparatus, and vacuum freeze-drying apparatus
JP6887050B1 (en) * 2020-08-07 2021-06-16 株式会社アルバック Vacuum freeze-drying method and vacuum freeze-drying equipment
WO2022104274A1 (en) * 2020-11-16 2022-05-19 Sublime Stericeuticals Corporation Continuous throughput lyophilizer/powder filler within a sterile boundary
CN116648300A (en) * 2020-12-11 2023-08-25 默沙东有限责任公司 Compact containment systems for isolating, processing and packaging pharmaceutical products
JP7085088B1 (en) * 2021-08-03 2022-06-16 株式会社エムアイアイ Freeze-dried
CN113701457A (en) * 2021-09-18 2021-11-26 楚天科技股份有限公司 Freeze-drying system and freeze-drying method
IL311906A (en) 2021-10-05 2024-06-01 Sanofi Sa Methods for freezing and freeze drying lipid nanoparticles (LNPs) and LNPs obtained from them
US12085337B2 (en) 2021-10-20 2024-09-10 DSM Sales & Manufacturing, Inc. Freeze-drying systems and methods
CN114192067A (en) * 2021-12-08 2022-03-18 南通东概念新材料有限公司 A method for preparing granules by spray drying, liquid nitrogen quick freezing and vacuum freeze drying
TW202417038A (en) 2022-06-15 2024-05-01 法商賽諾菲公司 Highly concentrated antibody compositions
US11975274B2 (en) 2022-09-15 2024-05-07 Velico Medical, Inc. Blood plasma product
US12083447B2 (en) 2022-09-15 2024-09-10 Velico Medical, Inc. Alignment of a disposable for a spray drying plasma system
US11841189B1 (en) 2022-09-15 2023-12-12 Velico Medical, Inc. Disposable for a spray drying system
US11998861B2 (en) 2022-09-15 2024-06-04 Velico Medical, Inc. Usability of a disposable for a spray drying plasma system
US12246266B2 (en) 2022-09-15 2025-03-11 Velico Medical, Inc. Disposable for a spray drying system
US12246093B2 (en) 2022-09-15 2025-03-11 Velico Medical, Inc. Methods for making spray dried plasma
WO2024184725A1 (en) * 2023-03-03 2024-09-12 Pfizer Inc. Systems and methods for reducing electrostatic force in dynamic freeze drying
WO2024184721A1 (en) * 2023-03-03 2024-09-12 Pfizer Inc. Systems and methods for pre-conditioning frozen bulk in dynamic bulk freeze drying

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2388917A (en) * 1941-10-13 1945-11-13 Hormel & Co Geo A Process for preservation of biological materials and products resulting therefrom
FR1378749A (en) * 1964-01-07 1964-11-13 Leybold Hochvakuum Anlagen Freezing drying method and device
US3303578A (en) 1964-07-29 1967-02-14 William C Rockwell Continuous freeze-drying apparatus
US3601901A (en) 1969-09-12 1971-08-31 Earl L Rader Freeze drying apparatus with removable conveyor and heater structures
US3621587A (en) 1970-08-06 1971-11-23 Smitherm Industries Freeze drying apparatus
US4033048A (en) * 1976-01-12 1977-07-05 Clayton Van Ike Freeze drying apparatus
JPS5844703Y2 (en) 1979-02-01 1983-10-11 クラリオン株式会社 Speaker mounting structure
JPS55112980A (en) * 1979-02-26 1980-09-01 Nippon Oxygen Co Ltd Freezing drier
DE3105623A1 (en) 1981-02-16 1982-09-02 Erhard Dipl.-Ing.agr. 8000 München Grolitsch Process for the gentle freeze-drying and pulverisation of sensitive goods to be dried such as water-containing foods
AU650045B2 (en) 1990-09-12 1994-06-09 Lifecell Corporation Method and apparatus for cryopreparation dry stabilization and rehydration of biological suspensions
DE4113512C2 (en) * 1991-04-25 1995-04-20 Grolitsch Lisbeth Method and device for freeze drying and pulverizing food
US5230162A (en) * 1992-06-26 1993-07-27 Oyler Jr James R Systems and methods for the deliquification of liquid-containing substances by flash sublimation
GB9416582D0 (en) * 1994-08-17 1994-10-19 Ici Plc Process for the production of exothermically reacting compositions
AU699042B2 (en) 1995-03-09 1998-11-19 Boc Group, Inc., The Transfer port system
JPH0971536A (en) 1995-07-03 1997-03-18 Nippon Telegr & Teleph Corp <Ntt> Biological cell-containing liquid lyophilizer
DE19654134C2 (en) 1996-04-25 2003-08-07 Messer Griesheim Gmbh Freeze drying method and apparatus
JP3639783B2 (en) 2000-10-30 2005-04-20 共和真空技術株式会社 Freeze-drying method and freeze-drying equipment for food and medicine
GB0103620D0 (en) * 2001-02-14 2001-03-28 Prometic Biosciences Ltd Sterile composition and its preparation
US6543155B2 (en) 2001-03-01 2003-04-08 National Agricultural Research Organization Freeze-dried product and process and apparatus for producing it
JP3686594B2 (en) 2001-06-14 2005-08-24 共和真空技術株式会社 Dispensing equipment for liquid materials in freeze-drying equipment for foods and pharmaceuticals
WO2003043574A2 (en) 2001-11-19 2003-05-30 Becton, Dickinson And Company Pharmaceutical compositions in particulate form
JP3942093B2 (en) * 2003-01-28 2007-07-11 株式会社アルバック Spray type vacuum freeze dryer
FR2862306B1 (en) 2003-11-17 2008-05-30 Aventis Pasteur VACCINE COMPOSITION
DE102004005660A1 (en) 2004-02-04 2005-08-25 Rheinische Friedrich-Wilhelms-Universität Bonn Producing a lyophilized pharmaceutical material involves injection of a solution of the material into a vertical freezer pipe and precipitation of the resulting ice particles by gravity
SE526792C2 (en) 2004-03-03 2005-11-08 Tetra Laval Holdings & Finance Apparatus for evaporative cooling of a liquid product
BRPI0510529A (en) 2004-05-01 2007-10-30 Agres Ltd drying process and apparatus
EP1794524B1 (en) 2004-07-23 2012-01-18 Bayer Technology Services GmbH Sterile freezing, drying, storing, assaying and filling process (sfd-saf process) (pellet freeze-drying process for parenteral biopharmaceuticals)
US20060165717A1 (en) 2005-01-25 2006-07-27 Sanofi Pasteur DCchol in newborns
AR054822A1 (en) 2005-07-07 2007-07-18 Sanofi Pasteur ADMISSION IMMUNE EMULSION
EP2001498A4 (en) 2006-03-20 2013-01-23 Vertex Pharma Pharmaceutical compositions
EP2043682B1 (en) 2006-07-17 2014-04-02 GlaxoSmithKline Biologicals S.A. Influenza vaccine
DE202006018276U1 (en) 2006-12-01 2007-02-08 Püschner GmbH + Co. KG Microwave-vacuum drying system for drying e.g. lumpy goods, has plastic drum with unsealed opening, which is selectively brought under inlet and outlet openings of vacuum container by rotation of drum
DE102007055488B4 (en) * 2006-12-01 2015-01-22 Püschner GmbH + Co. KG Microwave vacuum drying plant for drying lumpy, powdery or granular material
CN101234257B (en) 2007-02-01 2011-07-27 发泰(天津)科技有限公司 Microwave rotating thin film concentrator
DE102007012795B3 (en) * 2007-03-16 2008-04-10 Püschner GmbH + Co. KG Microwave-vacuum drying equipment for drying goods in pieces, powder-form or granular-form using microwaves in vacuum container, has microwave connecting components for connecting microwave generators into interior of vacuum container
EP2101131A1 (en) * 2007-12-31 2009-09-16 Terruzzi Fercalx S.p.A. Lyophilization method and system therefor
WO2009109550A1 (en) 2008-03-05 2009-09-11 Sanofi Pasteur Process for stabilizing an adjuvant containing vaccine composition
EP2578974A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Process line for the production of freeze-dried particles
EP2578975A1 (en) 2011-10-05 2013-04-10 Sanofi Pasteur Sa Rotary drum freeze-dryer
EP2578976A1 (en) 2011-10-06 2013-04-10 Sanofi Pasteur Sa Rotary drum for use in a vacuum freeze-dryer
UA111631C2 (en) 2011-10-06 2016-05-25 Санофі Пастер Са HEATING DEVICE FOR ROTOR DRUM LYOPHILE DRYER

Also Published As

Publication number Publication date
IL231853A0 (en) 2014-05-28
ES2608478T3 (en) 2017-04-11
IN2014CN02407A (en) 2015-06-19
EP2764309B1 (en) 2016-11-23
DK2766682T3 (en) 2017-01-09
MX359904B (en) 2018-10-16
KR101552804B1 (en) 2015-09-11
MY151369A (en) 2014-05-16
CN103917842B (en) 2015-08-05
CA2849799A1 (en) 2013-04-11
CR20140158A (en) 2014-10-30
WO2013050156A8 (en) 2013-06-13
BR112014007862A2 (en) 2017-04-18
WO2013050162A1 (en) 2013-04-11
DK2764309T3 (en) 2017-01-09
EA201490719A1 (en) 2014-09-30
BR112014008001A2 (en) 2017-04-11
MX341894B (en) 2016-09-07
HUE030970T2 (en) 2017-06-28
SG11201400641QA (en) 2014-08-28
AU2012320854A1 (en) 2014-05-15
CO6930351A2 (en) 2014-04-28
MX2014004000A (en) 2014-07-22
KR20140088112A (en) 2014-07-09
CN103917842A (en) 2014-07-09
PE20142141A1 (en) 2015-01-04
ES2608427T3 (en) 2017-04-10
EP2766682A1 (en) 2014-08-20
MY152319A (en) 2014-09-08
PE20141979A1 (en) 2014-12-19
EA027630B1 (en) 2017-08-31
JP2014530061A (en) 2014-11-17
HUE029973T2 (en) 2017-04-28
UA111858C2 (en) 2016-06-24
EP2764309A1 (en) 2014-08-13
US20140245629A1 (en) 2014-09-04
JP5728135B2 (en) 2015-06-03
ZA201401930B (en) 2015-02-25
CA2849802C (en) 2015-12-08
HK1199656A1 (en) 2015-07-10
AU2012320848A1 (en) 2014-05-15
CA2849799C (en) 2015-12-08
PH12014500617A1 (en) 2019-06-03
US10006706B2 (en) 2018-06-26
KR20140088113A (en) 2014-07-09
JP2014530685A (en) 2014-11-20
JP5766361B2 (en) 2015-08-19
AU2012320848B8 (en) 2015-03-05
BR112014008001B1 (en) 2021-01-19
EP2766682B1 (en) 2016-11-23
EP3211355A1 (en) 2017-08-30
HK1200207A1 (en) 2015-07-31
WO2013050156A1 (en) 2013-04-11
CN103917841B (en) 2015-07-08
EP2578974A1 (en) 2013-04-10
EA201490723A1 (en) 2014-08-29
UA111859C2 (en) 2016-06-24
US9920989B2 (en) 2018-03-20
CN103917841A (en) 2014-07-09
BR112014007862B1 (en) 2021-01-19
CA2849802A1 (en) 2013-04-11
KR101512608B1 (en) 2015-04-15
PL2766682T3 (en) 2017-03-31
AU2012320854B2 (en) 2015-02-19
AU2012320848B2 (en) 2015-02-26
IL231849A0 (en) 2014-05-28
CO6930306A2 (en) 2014-04-28
CR20140159A (en) 2014-10-30
PH12014500621A1 (en) 2014-05-05
US20140230266A1 (en) 2014-08-21
PL2764309T3 (en) 2017-03-31
IN2014CN02440A (en) 2015-06-19
EA027602B1 (en) 2017-08-31
MX2014004041A (en) 2014-08-01

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