SG11201400277VA - New enzyme inhibitor compounds - Google Patents

New enzyme inhibitor compounds

Info

Publication number: SG11201400277VA
Authority: SG; Singapore
Prior art keywords: enzyme inhibitor; inhibitor compounds; new enzyme; new; compounds
Prior art date: 2011-09-14

Application number

SG11201400277VA

Inventor

David Evans

Allison Carley

Alison Stewart

Michael Higginbottom

Edward Savory

Iain Simpson

Marianne Nilsson

Martin Haraldsson

Erik Nordling

Tobias Koolmeister

Original Assignee

Proximagen Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-09-14

Filing date

2011-09-14

Publication date

2014-05-29

2011-09-14 Application filed by Proximagen Ltd filed Critical Proximagen Ltd

2014-05-29 Publication of SG11201400277VA publication Critical patent/SG11201400277VA/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Immunology (AREA)
Cardiology (AREA)
Pulmonology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Rheumatology (AREA)
Hospice & Palliative Care (AREA)
Dermatology (AREA)
Hematology (AREA)
Endocrinology (AREA)
Transplantation (AREA)
Pain & Pain Management (AREA)
Communicable Diseases (AREA)
Obesity (AREA)
Vascular Medicine (AREA)
Oncology (AREA)
Psychiatry (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Gastroenterology & Hepatology (AREA)

SG11201400277VA 2011-09-14 2011-09-14 New enzyme inhibitor compounds SG11201400277VA (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/EP2011/065967 WO2013037411A1 (en)	2011-09-14	2011-09-14	New enzyme inhibitor compounds

Publications (1)

Publication Number	Publication Date
SG11201400277VA true SG11201400277VA (en)	2014-05-29

Family

ID=44677871

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SG11201400277VA SG11201400277VA (en)	2011-09-14	2011-09-14	New enzyme inhibitor compounds

Country Status (12)

Country	Link
US (1)	US9150574B2 (en)
EP (1)	EP2755974A1 (en)
JP (1)	JP5796130B2 (en)
CN (1)	CN103889983B (en)
AU (1)	AU2011376717A1 (en)
BR (1)	BR112014005793A2 (en)
CA (1)	CA2847193A1 (en)
EA (1)	EA201490451A1 (en)
IL (1)	IL231353A0 (en)
IN (1)	IN2014DN01883A (en)
SG (1)	SG11201400277VA (en)
WO (1)	WO2013037411A1 (en)

Families Citing this family (13)

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GB201304527D0 (en)	2013-03-13	2013-04-24	Proximagen Ltd	New compounds
GB201304526D0 (en) *	2013-03-13	2013-04-24	Proximagen Ltd	New compounds
US20160113893A1 (en)	2013-06-12	2016-04-28	Proximagen Limited	New therapeutic uses of enzyme inhibitors
GB201416446D0 (en)	2014-09-17	2014-10-29	Proximagen Ltd	New enzyme inhibitor compounds
GB201416444D0 (en)	2014-09-17	2014-10-29	Proximagen Ltd	New compounds
GB201507031D0 (en) *	2015-04-24	2015-06-10	Proximagen Ltd	New pharmaceutical salt forms
US20180360808A1 (en)	2015-12-07	2018-12-20	Benevolentai Cambridge Limited	Vap-1 inhibitors for treating pain
CN110291082A (en) *	2017-01-09	2019-09-27	阿德利克斯股份有限公司	Inhibitors of nhe-mediated antiport
CN112912141A (en) *	2018-08-27	2021-06-04	斯皮诺吉尼克斯公司	Fascin binding compounds for dendritic spine production
US20220227763A1 (en)	2019-05-29	2022-07-21	Syngenta Crop Protection Ag	Microbiocidal derivatives
WO2021209473A1 (en) *	2020-04-16	2021-10-21	F. Hoffmann-La Roche Ag	Biphenyl derivatives
PE20242359A1 (en)	2021-06-01	2024-12-16	Janssen Pharmaceutica Nv	SUBSTITUTED PHENYL-1H-PYRROLO[2,3-C]PYRIDINE DERIVATIVES
WO2023193790A1 (en) *	2022-04-08	2023-10-12	Janssen Pharmaceutica Nv	Crystalline forms of an inhibitor of the menin/mll interaction

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BR0014000A (en)	1999-09-14	2002-05-14	Aventis Pharma Inc	Benzisoxazolyl-, pyridoisoxazolyl- and benzthienyl-phenoxy derivatives useful as d4 antagonists
WO2002038153A1 (en)	2000-11-09	2002-05-16	Biovitrum Ab	New use of 4, 5, 6, 7-tetrahydroimidazo-[4,5-c]pyridine derivatives
US6982286B2 (en)	2001-07-12	2006-01-03	Biotie Therapies Corp.	Carbocyclic hydrazino inhibitors of copper-containing amine oxidases
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WO2005014530A2 (en)	2003-08-08	2005-02-17	La Jolla Pharmaceutical Co.	Inhibitors of semicarbazide-sensitive amine oxidase (ssao) and vap-1 mediated adhesion useful for treatment of diseases
US7402680B2 (en)	2003-09-17	2008-07-22	Janssen Pharmaceutica, N.V.	Fused heterocyclic compounds
CA2553724A1 (en)	2004-02-03	2005-08-18	Abbott Laboratories	Aminobenzoxazoles as therapeutic agents
TW200538453A (en)	2004-04-26	2005-12-01	Bristol Myers Squibb Co	Bicyclic heterocycles as kinase inhibitors
US8859581B2 (en)	2005-04-25	2014-10-14	Merck Patent Gmbh	Azaheterocyclic compounds as kinase inhibitors
UA95777C2 (en)	2005-06-22	2011-09-12	Кемосентрикс, Инк.	Azaindazole compounds and methods of use
US20070293548A1 (en)	2006-03-31	2007-12-20	Wang Eric Y	Inhibitors of semicarbazide-sensitive amine oxidase (SSAO) and VAP-1 mediated adhesion useful for treatment and prevention of diseases
US7696223B2 (en)	2006-04-04	2010-04-13	Fibrogen, Inc.	Pyrrolo- and Thiazolo-pyridine compounds, and methods of use thereof
GB0610242D0 (en)	2006-05-23	2006-07-05	Novartis Ag	Organic compounds
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EP2376490B1 (en)	2008-12-04	2013-01-23	Proximagen Limited	Imidazopyridine compounds
JP2012211085A (en)	2009-08-12	2012-11-01	Kyowa Hakko Kirin Co Ltd	Hedgehog signal inhibitor
GB201004311D0 (en) *	2010-03-15	2010-04-28	Proximagen Ltd	New enzyme inhibitor compounds
GB201115853D0 (en)	2011-09-14	2011-10-26	Proximagen Ltd	New enzyme inhibitor compounds

2011
- 2011-09-14 SG SG11201400277VA patent/SG11201400277VA/en unknown
- 2011-09-14 AU AU2011376717A patent/AU2011376717A1/en not_active Abandoned
- 2011-09-14 WO PCT/EP2011/065967 patent/WO2013037411A1/en active Application Filing
- 2011-09-14 CA CA2847193A patent/CA2847193A1/en not_active Abandoned
- 2011-09-14 EA EA201490451A patent/EA201490451A1/en unknown
- 2011-09-14 BR BR112014005793A patent/BR112014005793A2/en not_active IP Right Cessation
- 2011-09-14 JP JP2014530103A patent/JP5796130B2/en not_active Expired - Fee Related
- 2011-09-14 US US14/344,417 patent/US9150574B2/en not_active Expired - Fee Related
- 2011-09-14 CN CN201180073402.9A patent/CN103889983B/en not_active Expired - Fee Related
- 2011-09-14 EP EP11761040.2A patent/EP2755974A1/en not_active Withdrawn
- 2011-09-14 IN IN1883DEN2014 patent/IN2014DN01883A/en unknown
2014
- 2014-03-06 IL IL231353A patent/IL231353A0/en unknown

Also Published As

Publication number	Publication date
US9150574B2 (en)	2015-10-06
IL231353A0 (en)	2014-04-30
WO2013037411A1 (en)	2013-03-21
BR112014005793A2 (en)	2017-03-28
EA201490451A1 (en)	2014-12-30
AU2011376717A1 (en)	2014-03-20
JP5796130B2 (en)	2015-10-21
CN103889983A (en)	2014-06-25
US20140357623A1 (en)	2014-12-04
EP2755974A1 (en)	2014-07-23
IN2014DN01883A (en)	2015-05-15
CN103889983B (en)	2015-12-09
JP2015502913A (en)	2015-01-29
CA2847193A1 (en)	2013-03-21

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