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SG11201400073SA - Peptide nanoparticles and uses thereof - Google Patents

Peptide nanoparticles and uses thereof

Info

Publication number
SG11201400073SA
SG11201400073SA SG11201400073SA SG11201400073SA SG11201400073SA SG 11201400073S A SG11201400073S A SG 11201400073SA SG 11201400073S A SG11201400073S A SG 11201400073SA SG 11201400073S A SG11201400073S A SG 11201400073SA SG 11201400073S A SG11201400073S A SG 11201400073SA
Authority
SG
Singapore
Prior art keywords
peptide nanoparticles
nanoparticles
peptide
Prior art date
Application number
SG11201400073SA
Inventor
Christian Dittrich
Gaudenz Danuser
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of SG11201400073SA publication Critical patent/SG11201400073SA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/7105Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/711Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088Compounds having three or more nucleosides or nucleotides
    • A61K31/713Double-stranded nucleic acids or oligonucleotides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816Wall or shell material
    • A61K9/4825Proteins, e.g. gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51Nanocapsules; Nanoparticles
    • A61K9/5107Excipients; Inactive ingredients
    • A61K9/513Organic macromolecular compounds; Dendrimers
    • A61K9/5169Proteins, e.g. albumin, gelatin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG11201400073SA 2011-08-23 2012-08-23 Peptide nanoparticles and uses thereof SG11201400073SA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161526526P 2011-08-23 2011-08-23
PCT/US2012/052027 WO2013028843A1 (en) 2011-08-23 2012-08-23 Peptide nanoparticles and uses thereof

Publications (1)

Publication Number Publication Date
SG11201400073SA true SG11201400073SA (en) 2014-03-28

Family

ID=46826904

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201400073SA SG11201400073SA (en) 2011-08-23 2012-08-23 Peptide nanoparticles and uses thereof

Country Status (19)

Country Link
US (1) US8828928B2 (en)
EP (1) EP2748182B1 (en)
JP (1) JP2014524477A (en)
KR (1) KR20140068087A (en)
CN (1) CN104011065B (en)
AU (1) AU2012298824B2 (en)
BR (1) BR112014004014A2 (en)
CA (1) CA2845886A1 (en)
CL (1) CL2014000418A1 (en)
DK (1) DK2748182T3 (en)
ES (1) ES2610779T3 (en)
HU (1) HUE031511T2 (en)
IL (1) IL231005A0 (en)
MX (1) MX2014002062A (en)
PT (1) PT2748182T (en)
RU (1) RU2014110901A (en)
SG (1) SG11201400073SA (en)
WO (1) WO2013028843A1 (en)
ZA (1) ZA201401210B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8153435B1 (en) 2005-03-30 2012-04-10 Tracer Detection Technology Corp. Methods and articles for identifying objects using encapsulated perfluorocarbon tracers
US11286489B2 (en) * 2016-02-11 2022-03-29 The Curators Of The University Of Missouri POSH inhibitor complex biomolecules and amphiphile micelles
EP3432908A4 (en) 2016-03-21 2020-07-29 Rhode Island Council on Postsecondary Education PH SENSITIVE PEPTIDES
CN109070040B (en) * 2016-12-16 2023-07-28 布里格姆及妇女医院股份有限公司 Systems and methods of protein corona sensor arrays for early detection of disease
CN106832003B (en) * 2017-02-15 2021-01-05 中国药科大学 Acid-sensitive polypeptide and application thereof
CN119185557A (en) 2018-04-06 2024-12-27 阿玛治疗公司 Compositions for controlled release of therapeutic agents
US12319711B2 (en) 2019-09-20 2025-06-03 Northwestern University Spherical nucleic acids with tailored and active protein coronae
US20220356303A1 (en) * 2021-04-08 2022-11-10 The Curators Of The University Of Missouri Lipidated poly(amino acid) nanostructures
CN114516819B (en) * 2022-02-25 2024-02-27 顺毅宜昌化工有限公司 Preparation method of N, N' -diacetyl hydrazine
WO2023244536A2 (en) * 2022-06-13 2023-12-21 Neubase Therapeutics, Inc. Oligonucleotide analogue formulations
CN116004221B (en) * 2022-12-15 2023-12-19 湖南卓润生物科技有限公司 New application of cyclic peptide, acridine labeled complex, preparation method and detection kit

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3270960A (en) 1964-09-11 1966-09-06 Sperry Rand Corp Fluid sensor
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US3872925A (en) 1973-04-24 1975-03-25 Gearhart Owen Industries Through-tubing bridge plug
US3842067A (en) 1973-07-27 1974-10-15 American Home Prod Synthesis of(des-asn5)-srif and intermediates
JPS5726506B2 (en) 1974-03-08 1982-06-04
US4105603A (en) 1977-03-28 1978-08-08 The Salk Institute For Biological Studies Peptides which effect release of hormones
US4511390A (en) 1983-06-10 1985-04-16 E. I. Du Pont De Nemours And Company Aralkylcarbamoyl peptide alcohols
US5643873A (en) 1992-05-06 1997-07-01 Affymax Technologies N.V. Peptides and compounds that bind selectins including endothelial leukocyte adhesion molecule 1
US5625048A (en) 1994-11-10 1997-04-29 The Regents Of The University Of California Modified green fluorescent proteins
US5654276A (en) 1995-06-07 1997-08-05 Affymax Technologies N.V. Peptides and compounds that bind to the IL-5 receptor
FR2736642B1 (en) 1995-07-10 1997-09-12 Pasteur Institut IMMUNOVECTORS, IN PARTICULAR ANTIBODIES AND FRAGMENTS OF ANTIBODIES FOR USE IN THE INTRACELLULAR AND INTRANUCLEAR TRANSPORT OF BIOLOGICALLY ACTIVE PRINCIPLES IN PARTICULAR OF HAPTENES, PROTEINS AND NUCLEIC ACIDS
US6124128A (en) 1996-08-16 2000-09-26 The Regents Of The University Of California Long wavelength engineered fluorescent proteins
EP1206494B1 (en) 1999-08-02 2004-11-03 Synt:Em S.A. Computational design methods for making molecular mimetics
EP1372418A4 (en) 2001-02-26 2006-01-25 Univ Non-oligomerizing tandem fluorescent proteins
US20060084607A1 (en) 2004-07-06 2006-04-20 Lisa Spirio Purified amphiphilic peptide compositions and uses thereof
CA2713879C (en) 2008-02-01 2020-01-07 Alpha-O Peptides Ag Self-assembling peptide nanoparticles useful as vaccines
JP2011523353A (en) * 2008-04-28 2011-08-11 プレジデント アンド フェロウズ オブ ハーバード カレッジ Overcharged protein for cell penetration

Also Published As

Publication number Publication date
CL2014000418A1 (en) 2014-07-25
EP2748182B1 (en) 2016-10-19
PT2748182T (en) 2017-01-20
JP2014524477A (en) 2014-09-22
IL231005A0 (en) 2014-03-31
DK2748182T3 (en) 2017-02-06
US20130064895A1 (en) 2013-03-14
ZA201401210B (en) 2015-12-23
CA2845886A1 (en) 2013-02-28
AU2012298824A1 (en) 2014-03-20
BR112014004014A2 (en) 2020-10-27
WO2013028843A1 (en) 2013-02-28
EP2748182A1 (en) 2014-07-02
HUE031511T2 (en) 2017-07-28
RU2014110901A (en) 2015-09-27
ES2610779T3 (en) 2017-05-03
MX2014002062A (en) 2014-05-28
CN104011065A (en) 2014-08-27
KR20140068087A (en) 2014-06-05
AU2012298824B2 (en) 2017-06-01
US8828928B2 (en) 2014-09-09
NZ622045A (en) 2016-02-26
CN104011065B (en) 2017-06-30

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