SG10202012842SA - Nonselective metabotropic glutamate receptor activators for treatment of attention deficit disorder and 22q syndrome - Google Patents
Nonselective metabotropic glutamate receptor activators for treatment of attention deficit disorder and 22q syndromeInfo
- Publication number
- SG10202012842SA SG10202012842SA SG10202012842SA SG10202012842SA SG10202012842SA SG 10202012842S A SG10202012842S A SG 10202012842SA SG 10202012842S A SG10202012842S A SG 10202012842SA SG 10202012842S A SG10202012842S A SG 10202012842SA SG 10202012842S A SG10202012842S A SG 10202012842SA
- Authority
- SG
- Singapore
- Prior art keywords
- syndrome
- treatment
- attention deficit
- glutamate receptor
- metabotropic glutamate
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562215673P | 2015-09-08 | 2015-09-08 | |
US201562215636P | 2015-09-08 | 2015-09-08 | |
US201562215628P | 2015-09-08 | 2015-09-08 | |
US201562215633P | 2015-09-08 | 2015-09-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG10202012842SA true SG10202012842SA (en) | 2021-01-28 |
Family
ID=56943962
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG10202012842SA SG10202012842SA (en) | 2015-09-08 | 2016-09-07 | Nonselective metabotropic glutamate receptor activators for treatment of attention deficit disorder and 22q syndrome |
Country Status (13)
Country | Link |
---|---|
US (12) | US11179378B2 (da) |
EP (12) | EP3347013B1 (da) |
JP (9) | JP7281280B2 (da) |
CN (7) | CN108601776A (da) |
AU (10) | AU2016318775B2 (da) |
CA (5) | CA2997189A1 (da) |
DK (4) | DK3347014T3 (da) |
ES (7) | ES2897953T3 (da) |
HK (4) | HK1258373A1 (da) |
IL (12) | IL303605A (da) |
PL (4) | PL3922249T3 (da) |
SG (1) | SG10202012842SA (da) |
WO (4) | WO2017044491A1 (da) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
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JP6216486B2 (ja) | 2010-08-24 | 2017-10-18 | ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアThe Children’S Hospital Of Philadelphia | 低頻度反復性遺伝的変異の注意欠陥多動性障害への関連ならびに診断および治療のためのその使用方法 |
DK3347014T3 (da) | 2015-09-08 | 2021-12-06 | Childrens Hospital Philadelphia | Fremgangsmåder til diagnosticering og behandling af Tourettes syndrom |
US20200143922A1 (en) * | 2016-06-03 | 2020-05-07 | Yale University | Methods and apparatus for predicting depression treatment outcomes |
EP3509640A1 (en) * | 2016-09-07 | 2019-07-17 | The Children's Hospital of Philadelphia | Nonselective metabotropic glutamate receptor activators for treatment of anorexia nervosa and binge eating disorder |
US11684617B2 (en) * | 2017-04-19 | 2023-06-27 | The Children's Hospital Of Philadelphia | Methods of diagnosing and treating ADHD in biomarker positive subjects |
WO2018209328A1 (en) * | 2017-05-11 | 2018-11-15 | Miwa Julie M | Compositions and methods for treating lynx2 disorders |
CN107483425B (zh) * | 2017-08-08 | 2020-12-18 | 北京盛华安信息技术有限公司 | 基于攻击链的复合攻击检测方法 |
EP3740204A4 (en) | 2018-01-18 | 2021-10-06 | The Children's Hospital Of Philadelphia | SOLID STATE FORMS OF FASORACETAM |
SG11202006813TA (en) | 2018-01-18 | 2020-08-28 | Childrens Hospital Philadelphia | Fasoracetam crystalline forms |
KR102250063B1 (ko) * | 2019-06-14 | 2021-05-12 | 한국생명공학연구원 | 뚜렛증후군의 원인 유전자를 동정하는 방법 |
CN110955751A (zh) * | 2019-11-13 | 2020-04-03 | 广州供电局有限公司 | 工作票文本去重方法、装置、系统及计算机存储介质 |
IL301500A (en) * | 2020-09-21 | 2023-05-01 | Reveragen Biopharma Inc | TREATMENT OF NF-κB-MEDIATED DISEASE |
WO2022065518A1 (ja) * | 2020-09-23 | 2022-03-31 | 国立大学法人京都大学 | 神経突起伸長促進剤 |
KR20240112047A (ko) * | 2023-01-11 | 2024-07-18 | 차의과학대학교 산학협력단 | 불안장애를 진단하기 위한 바이오마커 및 이의 용도 |
CN117594119B (zh) * | 2024-01-17 | 2024-05-10 | 北京大学第六医院 | 用于预测帕罗西汀或其药用盐对抑郁或焦虑症患者疗效的装置 |
Family Cites Families (26)
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AU2002245486B2 (en) | 2001-02-23 | 2006-11-16 | Ucb Pharma, S.A. | Treatment of tics, tremors and related disorders |
WO2003054167A2 (en) | 2001-12-20 | 2003-07-03 | Merck & Co., Inc. | Identification of novel polymorphic sites in the human mglur8 gene and uses thereof |
JP2007530591A (ja) | 2004-03-25 | 2007-11-01 | スミスクライン・ビーチャム・コーポレイション | 双極性障害を治療するための、nk3アンタゴニストの使用 |
US20100216734A1 (en) * | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
US20070244143A1 (en) | 2006-03-08 | 2007-10-18 | Braincells, Inc | Modulation of neurogenesis by nootropic agents |
TW200819458A (en) | 2006-06-23 | 2008-05-01 | Merz Pharma Gmbh & Co Kgaa | Metabotropic glutamate receptor modulators |
US20100120628A1 (en) | 2007-02-06 | 2010-05-13 | Genizon Biosciences Inc. | Genemap of the human genes associated with adhd |
EP2149047A4 (en) | 2007-04-30 | 2010-05-19 | Univ Ohio State Res Found | POLYMORPHISMS IN GENES WITH INFLUENCE ON DOPAMINTRANSPORTER DISEASES AND ITS APPLICATIONS |
US20090176740A1 (en) | 2007-11-30 | 2009-07-09 | Phillips Ii Dauglas James | Treatment of neurological conditions by the co-administration of aniracetam and l-alpha glycerylphosphorylcholine |
US9783851B2 (en) | 2008-02-20 | 2017-10-10 | The Children's Hospital Of Philadelphia | Genetic alterations associated with autism and the autistic phenotype and methods of use thereof for the diagnosis and treatment of autism |
JP2012511895A (ja) | 2008-11-14 | 2012-05-31 | ザ チルドレンズ ホスピタル オブ フィラデルフィア | ヒト認知の原因となる遺伝子変異体及び診断標的及び治療標的としてのそれらを使用する方法 |
WO2010057132A1 (en) | 2008-11-14 | 2010-05-20 | The Children's Hospital Of Philadelphia | Genetic alterations associated with schizophrenia and methods of use thereof for the diagnosis and treatment of the same |
WO2011022312A1 (en) | 2009-08-20 | 2011-02-24 | Merck Sharp & Dohme Corp. | Ether benzotriazole derivatives |
US8714471B2 (en) * | 2010-07-29 | 2014-05-06 | Brady Worldwide, Inc. | Friction core brake |
JP6216486B2 (ja) | 2010-08-24 | 2017-10-18 | ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィアThe Children’S Hospital Of Philadelphia | 低頻度反復性遺伝的変異の注意欠陥多動性障害への関連ならびに診断および治療のためのその使用方法 |
US20130225623A1 (en) | 2010-10-27 | 2013-08-29 | Mount Sinai School Of Medicine | Methods of Treating Psychiatric or Neurological Disorders with MGLUR Antagonists |
US20140315992A1 (en) | 2011-07-07 | 2014-10-23 | The Children's Hospital Of Philadelphia | Genetic Alterations Associated with Autism and the Autistic Phenotype and Methods of Use Thereof for the Diagnosis and Treatment of Autism |
US20130143867A1 (en) * | 2011-12-02 | 2013-06-06 | Sychroneuron Inc. | Acamprosate formulations, methods of using the same, and combinations comprising the same |
US20140057988A1 (en) * | 2012-08-23 | 2014-02-27 | Stuart WEG | Anxiolytic composition, formulation and method of use |
US9346239B2 (en) | 2012-09-26 | 2016-05-24 | Eastman Kodak Company | Method for providing patterns of functional materials |
WO2014152965A2 (en) | 2013-03-14 | 2014-09-25 | The Children's Hospital Of Philadelphia | Schizophrenia-associated genetic loci identified in genome wide association studies and use thereof as novel therapeutic targets |
AU2015298618A1 (en) | 2014-05-30 | 2016-12-08 | The Children's Hospital Of Philadelphia | Genetic alterations associated with autism and autistic phenotype and methods of diagnosing and treating autism |
US11219617B2 (en) | 2014-05-30 | 2022-01-11 | The Children's Hospital Of Philadelphia | Methods of diagnosing and treating autism |
KR102232583B1 (ko) | 2015-01-08 | 2021-03-26 | 삼성전자주식회사 | 전자장치 및 전자장치의 웹 재현 방법 |
AU2016278053A1 (en) | 2015-06-15 | 2018-01-04 | The Children's Hospital Of Philadelphia | Methods of diagnosing and treating autism |
DK3347014T3 (da) | 2015-09-08 | 2021-12-06 | Childrens Hospital Philadelphia | Fremgangsmåder til diagnosticering og behandling af Tourettes syndrom |
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2016
- 2016-09-07 DK DK16767114.8T patent/DK3347014T3/da active
- 2016-09-07 WO PCT/US2016/050559 patent/WO2017044491A1/en active Application Filing
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- 2016-09-07 EP EP16767112.2A patent/EP3347013B1/en active Active
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- 2016-09-07 EP EP24162566.4A patent/EP4410288A1/en active Pending
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2020
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2021
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2022
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2023
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