SG10202003753PA - Highly potent acid alpha-glucosidase with enhanced carbohydrates - Google Patents
Highly potent acid alpha-glucosidase with enhanced carbohydratesInfo
- Publication number
- SG10202003753PA SG10202003753PA SG10202003753PA SG10202003753PA SG10202003753PA SG 10202003753P A SG10202003753P A SG 10202003753PA SG 10202003753P A SG10202003753P A SG 10202003753PA SG 10202003753P A SG10202003753P A SG 10202003753PA SG 10202003753P A SG10202003753P A SG 10202003753PA
- Authority
- SG
- Singapore
- Prior art keywords
- glucosidase
- highly potent
- acid alpha
- carbohydrates
- enhanced
- Prior art date
Links
- 102100024295 Maltase-glucoamylase Human genes 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 108010028144 alpha-Glucosidases Proteins 0.000 title 1
- 150000001720 carbohydrates Chemical class 0.000 title 1
- 235000014633 carbohydrates Nutrition 0.000 title 1
- 230000003389 potentiating effect Effects 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/0102—Alpha-glucosidase (3.2.1.20)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462057847P | 2014-09-30 | 2014-09-30 | |
| US201462057842P | 2014-09-30 | 2014-09-30 | |
| US201562112463P | 2015-02-05 | 2015-02-05 | |
| US201562135345P | 2015-03-19 | 2015-03-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10202003753PA true SG10202003753PA (en) | 2020-05-28 |
Family
ID=55631441
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201702114TA SG11201702114TA (en) | 2014-09-30 | 2015-09-30 | Highly potent acid alpha-glucosidase with enhanced carbohydrates |
| SG10202003753PA SG10202003753PA (en) | 2014-09-30 | 2015-09-30 | Highly potent acid alpha-glucosidase with enhanced carbohydrates |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201702114TA SG11201702114TA (en) | 2014-09-30 | 2015-09-30 | Highly potent acid alpha-glucosidase with enhanced carbohydrates |
Country Status (39)
| Country | Link |
|---|---|
| US (5) | US10208299B2 (en) |
| EP (3) | EP4273241B1 (en) |
| JP (3) | JP6851964B2 (en) |
| KR (4) | KR102741048B1 (en) |
| CN (2) | CN114540327A (en) |
| AU (3) | AU2015325028B2 (en) |
| BR (1) | BR112017005810A2 (en) |
| CA (2) | CA3228032A1 (en) |
| CL (1) | CL2017000722A1 (en) |
| CO (1) | CO2017002776A2 (en) |
| CR (1) | CR20170107A (en) |
| CY (2) | CY1126544T1 (en) |
| DK (2) | DK4273241T3 (en) |
| DO (1) | DOP2017000079A (en) |
| EA (1) | EA038986B1 (en) |
| EC (1) | ECSP17019103A (en) |
| ES (2) | ES2967620T3 (en) |
| FI (4) | FI4273241T3 (en) |
| FR (1) | FR24C1012I1 (en) |
| HR (2) | HRP20250058T1 (en) |
| HU (4) | HUE070443T2 (en) |
| IL (4) | IL289383B2 (en) |
| LT (2) | LT3201320T (en) |
| MX (2) | MX388241B (en) |
| MY (1) | MY186336A (en) |
| NI (1) | NI201700039A (en) |
| NO (1) | NO2025023I1 (en) |
| PE (1) | PE20170906A1 (en) |
| PH (1) | PH12017500455A1 (en) |
| PL (2) | PL4273241T3 (en) |
| PT (2) | PT4273241T (en) |
| RS (2) | RS66510B1 (en) |
| SG (2) | SG11201702114TA (en) |
| SI (2) | SI4273241T1 (en) |
| SM (2) | SMT202500074T1 (en) |
| SV (1) | SV2017005416A (en) |
| TN (1) | TN2017000082A1 (en) |
| WO (1) | WO2016054231A1 (en) |
| ZA (2) | ZA201701945B (en) |
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| HRP20250058T1 (en) | 2014-09-30 | 2025-03-28 | Amicus Therapeutics, Inc. | VERY STRONG ACID ALPHA-GLUCOSIDASE WITH ENHANCED CARBOHYDRATES |
| ES2965190T3 (en) * | 2015-12-30 | 2024-04-11 | Amicus Therapeutics Inc | Increased acid alpha-glucosidase for the treatment of Pompe disease |
| MX394968B (en) * | 2015-12-30 | 2025-03-24 | Amicus Therapeutics Inc | ALPHA-GLUCOSIDASE WITH HIGHER ACID FOR THE TREATMENT OF POMPE DISEASE. |
| BR112018069965A2 (en) | 2016-03-30 | 2019-01-29 | Amicus Therapeutics Inc | formulations comprising recombinant acid alpha glucosidase |
| BR112018070189A2 (en) * | 2016-03-30 | 2019-02-19 | Amicus Therapeutics, Inc. | method for selection of m6p rich recombinant proteins |
| CN118581067A (en) * | 2016-03-30 | 2024-09-03 | 阿米库斯治疗学公司 | Method for selecting high M6P recombinant proteins |
| JP2020503900A (en) | 2017-01-10 | 2020-02-06 | アミカス セラピューティックス インコーポレイテッド | Recombinant alpha-galactosidase A for the treatment of Fabry disease |
| EA039750B1 (en) * | 2017-03-30 | 2022-03-10 | Амикус Терапьютикс, Инк. | Method for selection of high m6p recombinant proteins |
| CN111356474A (en) * | 2017-05-15 | 2020-06-30 | 阿米库斯治疗学公司 | Recombinant human acid alpha-glucosidase |
| WO2020028864A1 (en) | 2018-08-02 | 2020-02-06 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy |
| CN114341333A (en) * | 2019-09-06 | 2022-04-12 | 阿米库斯治疗学公司 | Method for capturing and purifying biological products |
| KR20230155622A (en) * | 2021-02-11 | 2023-11-10 | 아미쿠스 세라퓨틱스, 인코포레이티드 | Recombinant human acid alpha-glucosidase and uses thereof |
| WO2023150387A1 (en) * | 2022-02-07 | 2023-08-10 | M6P Therapeutics, Inc. | Compositions comprising acid alpha glucosidase and methods of use thereof |
| WO2023215865A1 (en) | 2022-05-05 | 2023-11-09 | Amicus Therapeutics, Inc. | Methods for treating pompe disease |
| TW202436620A (en) * | 2022-12-02 | 2024-09-16 | 美商阿米庫斯醫療股份有限公司 | Methods for treating infantile-onset pompe disease in pediatric patients |
| WO2024119070A1 (en) * | 2022-12-02 | 2024-06-06 | Amicus Therapeutics, Inc. | Methods for treating late onset pompe disease in pediatric patients |
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-
2015
- 2015-09-30 HR HRP20250058TT patent/HRP20250058T1/en unknown
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