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SG10201710578TA - Crystalline (8s,9r)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1h-1,2,4-triazol-5-yl)-8,9-dihydro-2h-pyrido[4,3,2-de]phthalazin-3(7h)-one tosylate salt - Google Patents

Crystalline (8s,9r)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1h-1,2,4-triazol-5-yl)-8,9-dihydro-2h-pyrido[4,3,2-de]phthalazin-3(7h)-one tosylate salt

Info

Publication number
SG10201710578TA
SG10201710578TA SG10201710578TA SG10201710578TA SG10201710578TA SG 10201710578T A SG10201710578T A SG 10201710578TA SG 10201710578T A SG10201710578T A SG 10201710578TA SG 10201710578T A SG10201710578T A SG 10201710578TA SG 10201710578T A SG10201710578T A SG 10201710578TA
Authority
SG
Singapore
Prior art keywords
phthalazin
pyrido
triazol
fluorophenyl
dihydro
Prior art date
Application number
SG10201710578TA
Other languages
English (en)
Inventor
Bing Wang
Daniel Chu
Yongbo Liu
Shichun Peng
Original Assignee
Medivation Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=44903424&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG10201710578T(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Medivation Technologies Inc filed Critical Medivation Technologies Inc
Publication of SG10201710578TA publication Critical patent/SG10201710578TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06Peri-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/5025Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG10201710578TA 2010-10-21 2011-10-20 Crystalline (8s,9r)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1h-1,2,4-triazol-5-yl)-8,9-dihydro-2h-pyrido[4,3,2-de]phthalazin-3(7h)-one tosylate salt SG10201710578TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US40547610P 2010-10-21 2010-10-21

Publications (1)

Publication Number Publication Date
SG10201710578TA true SG10201710578TA (en) 2018-02-27

Family

ID=44903424

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201710578TA SG10201710578TA (en) 2010-10-21 2011-10-20 Crystalline (8s,9r)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1h-1,2,4-triazol-5-yl)-8,9-dihydro-2h-pyrido[4,3,2-de]phthalazin-3(7h)-one tosylate salt
SG2013029731A SG189939A1 (en) 2010-10-21 2011-10-20 Crystalline (8s,9r)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1h-1,2,4-triazol-5-yl)-8,9-dihydro-2h-pyrido[4,3,2-de]phthalazin-3(7h)-one tosylate salt

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2013029731A SG189939A1 (en) 2010-10-21 2011-10-20 Crystalline (8s,9r)-5-fluoro-8-(4-fluorophenyl)-9-(1-methyl-1h-1,2,4-triazol-5-yl)-8,9-dihydro-2h-pyrido[4,3,2-de]phthalazin-3(7h)-one tosylate salt

Country Status (24)

Country Link
US (3) US8735392B2 (fr)
EP (2) EP2630146B1 (fr)
JP (6) JP2013540158A (fr)
KR (4) KR20180069132A (fr)
CN (1) CN103282365B (fr)
AR (1) AR083502A1 (fr)
AU (2) AU2011317040B2 (fr)
BR (1) BR112013009117A2 (fr)
CA (1) CA2814581C (fr)
CY (1) CY1123356T1 (fr)
DK (1) DK2630146T3 (fr)
ES (1) ES2816600T3 (fr)
HU (1) HUE051535T2 (fr)
IL (2) IL225789B (fr)
MX (1) MX362563B (fr)
NZ (1) NZ609490A (fr)
PL (1) PL2630146T3 (fr)
PT (1) PT2630146T (fr)
RU (1) RU2598606C3 (fr)
SG (2) SG10201710578TA (fr)
SI (1) SI2630146T1 (fr)
TW (2) TWI643858B (fr)
WO (1) WO2012054698A1 (fr)
ZA (1) ZA201302810B (fr)

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