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SG10201703678TA - Antibodies to s. aureus surface determinants - Google Patents

Antibodies to s. aureus surface determinants

Info

Publication number
SG10201703678TA
SG10201703678TA SG10201703678TA SG10201703678TA SG10201703678TA SG 10201703678T A SG10201703678T A SG 10201703678TA SG 10201703678T A SG10201703678T A SG 10201703678TA SG 10201703678T A SG10201703678T A SG 10201703678TA SG 10201703678T A SG10201703678T A SG 10201703678TA
Authority
SG
Singapore
Prior art keywords
antibodies
surface determinants
aureus surface
aureus
determinants
Prior art date
Application number
SG10201703678TA
Inventor
Bret Sellman
Christine Tkaczyk
Partha Chowdhury
Lei Hua
Peter Pavlik
Rebecca Buonpane
Chew-Shun Chang
Original Assignee
Medimmune Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medimmune Llc filed Critical Medimmune Llc
Publication of SG10201703678TA publication Critical patent/SG10201703678TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56938Staphylococcus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507Comprising a combination of two or more separate antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/567Framework region [FR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SG10201703678TA 2012-11-06 2013-11-06 Antibodies to s. aureus surface determinants SG10201703678TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261723137P 2012-11-06 2012-11-06
US201361782405P 2013-03-14 2013-03-14

Publications (1)

Publication Number Publication Date
SG10201703678TA true SG10201703678TA (en) 2017-06-29

Family

ID=50685304

Family Applications (2)

Application Number Title Priority Date Filing Date
SG11201503232TA SG11201503232TA (en) 2012-11-06 2013-11-06 Antibodies to s. aureus surface determinants
SG10201703678TA SG10201703678TA (en) 2012-11-06 2013-11-06 Antibodies to s. aureus surface determinants

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG11201503232TA SG11201503232TA (en) 2012-11-06 2013-11-06 Antibodies to s. aureus surface determinants

Country Status (17)

Country Link
US (3) US9879070B2 (en)
EP (2) EP3640338A1 (en)
JP (2) JP6694269B2 (en)
KR (1) KR102288394B1 (en)
CN (2) CN109553681A (en)
AU (2) AU2013341361A1 (en)
BR (1) BR112015010125A2 (en)
CA (1) CA2890427C (en)
DK (1) DK2917360T3 (en)
ES (1) ES2776179T3 (en)
HK (2) HK1215054A1 (en)
HU (1) HUE049012T2 (en)
MX (2) MX375324B (en)
PL (1) PL2917360T3 (en)
RU (1) RU2698131C2 (en)
SG (2) SG11201503232TA (en)
WO (1) WO2014074540A2 (en)

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ES2859323T3 (en) * 2011-11-07 2021-10-01 Medimmune Ltd Combination therapies using Pseudomonas anti-Psl and PcrV binding molecules
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US9988439B2 (en) 2011-12-23 2018-06-05 Nicholas B. Lydon Immunoglobulins and variants directed against pathogenic microbes
ES2912267T3 (en) 2012-11-06 2022-05-25 Medimmune Llc Treatment methods for diseases associated with S. aureus
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CN112538112B (en) * 2019-09-20 2023-10-27 迈威(上海)生物科技股份有限公司 Antibodies against alpha-hemolysin and uses thereof
KR102397684B1 (en) * 2019-12-09 2022-05-13 (주)옵토레인 Peptides binding to antibodies and analyzing method using the same
KR102504175B1 (en) * 2020-06-17 2023-02-28 (주)옵토레인 Peptides binding to antibodies, drug complex, biosensor and analyzing method using the same
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KR102674098B1 (en) * 2021-01-14 2024-06-12 (주)옵토레인 Switching peptides and multiplex immunoassay method using the switching peptides
KR102674120B1 (en) * 2021-01-18 2024-06-12 (주)옵토레인 Switching peptides and immunoassay method using the switching peptides

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Also Published As

Publication number Publication date
CA2890427C (en) 2022-05-31
EP3640338A1 (en) 2020-04-22
RU2019122610A (en) 2020-02-18
HK1215054A1 (en) 2016-08-12
MX2015005477A (en) 2015-11-30
BR112015010125A2 (en) 2017-08-22
HK1215452A1 (en) 2016-08-26
EP2917360A4 (en) 2017-01-25
US9879070B2 (en) 2018-01-30
AU2018241107B2 (en) 2020-09-17
KR102288394B1 (en) 2021-08-09
MX375324B (en) 2025-03-06
US20190016787A1 (en) 2019-01-17
US11447543B2 (en) 2022-09-20
CN104968797A (en) 2015-10-07
EP2917360A2 (en) 2015-09-16
MX2022008079A (en) 2022-07-11
CN109553681A (en) 2019-04-02
PL2917360T3 (en) 2020-06-29
US20150291685A1 (en) 2015-10-15
RU2015121624A (en) 2016-12-27
DK2917360T3 (en) 2020-03-30
WO2014074540A3 (en) 2014-07-10
JP6694269B2 (en) 2020-05-13
AU2018241107A1 (en) 2018-10-25
US10730934B2 (en) 2020-08-04
CN104968797B (en) 2018-11-30
JP2016507470A (en) 2016-03-10
JP2019089801A (en) 2019-06-13
RU2698131C2 (en) 2019-08-22
ES2776179T3 (en) 2020-07-29
US20200407429A1 (en) 2020-12-31
WO2014074540A2 (en) 2014-05-15
AU2013341361A1 (en) 2015-06-04
HUE049012T2 (en) 2020-09-28
SG11201503232TA (en) 2015-05-28
EP2917360B1 (en) 2020-01-08
CA2890427A1 (en) 2014-05-15
KR20150094621A (en) 2015-08-19

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