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SG10201701063WA - Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same - Google Patents

Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same

Info

Publication number
SG10201701063WA
SG10201701063WA SG10201701063WA SG10201701063WA SG10201701063WA SG 10201701063W A SG10201701063W A SG 10201701063WA SG 10201701063W A SG10201701063W A SG 10201701063WA SG 10201701063W A SG10201701063W A SG 10201701063WA SG 10201701063W A SG10201701063W A SG 10201701063WA
Authority
SG
Singapore
Prior art keywords
aqueous dispersion
encapsulating liposome
liposome aqueous
stable oxaliplatin
stabilizing same
Prior art date
Application number
SG10201701063WA
Inventor
Yusuke Doi
Tatsuhiro Ishida
Original Assignee
Taiho Pharmaceutical Co Ltd
Univ Tokushima
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd, Univ Tokushima filed Critical Taiho Pharmaceutical Co Ltd
Publication of SG10201701063WA publication Critical patent/SG10201701063WA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG10201701063WA 2012-08-10 2013-08-09 Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same SG10201701063WA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2012178971 2012-08-10

Publications (1)

Publication Number Publication Date
SG10201701063WA true SG10201701063WA (en) 2017-04-27

Family

ID=50068258

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201701063WA SG10201701063WA (en) 2012-08-10 2013-08-09 Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same
SG11201501010QA SG11201501010QA (en) 2012-08-10 2013-08-09 Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201501010QA SG11201501010QA (en) 2012-08-10 2013-08-09 Stable oxaliplatin-encapsulating liposome aqueous dispersion and method for stabilizing same

Country Status (7)

Country Link
US (2) US10383822B2 (en)
EP (1) EP2883542B1 (en)
JP (1) JP6230538B2 (en)
CN (1) CN104703594B (en)
ES (1) ES2733061T3 (en)
SG (2) SG10201701063WA (en)
WO (1) WO2014025042A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2015012200A (en) * 2013-03-13 2015-11-30 Mallinckrodt Llc Liposome oxaliplatin compositions for cancer therapy.
EP3350222B1 (en) 2015-09-18 2021-10-20 Technische Universität München Ligands for integrin avbeta6, synthesis and uses thereof
BR112019003946A2 (en) 2016-08-31 2019-05-21 Fujifilm Corporation antitumor agent, antitumor effect booster and antitumor kit
WO2018167295A1 (en) 2017-03-17 2018-09-20 Technische Universität München LIGANDS FOR INTEGRIN αvβ8, SYNTHESIS AND USES THEREOF
MX2018002611A (en) 2018-01-29 2019-07-30 Fujifilm Corp Antitumor agent for biliary cancer and treatment method of biliary cancer.
CN111836628B (en) * 2018-03-13 2025-01-07 富士胶片株式会社 Antitumor agent, antitumor effect enhancer, and antitumor kit

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1270198A (en) 1984-08-08 1990-06-12 Marcel B. Bally Encapsulation of antineoplastic agents in liposomes
JP3218637B2 (en) 1990-07-26 2001-10-15 大正製薬株式会社 Stable aqueous liposome suspension
EP0750910A4 (en) * 1994-03-11 1997-07-09 Yoshitomi Pharmaceutical LIPOSOME PREPARATION
ATE197249T1 (en) 1994-08-08 2000-11-15 Debiopharm Sa STABLE MEDICINAL PRODUCT CONTAINING OXALIPLATIN
GB9420390D0 (en) * 1994-10-10 1994-11-23 Nycomed Salutar Inc Liposomal agents
DE19648650C2 (en) 1996-01-29 1998-07-02 Schering Ag Buffer systems and their use to stabilize pharmaceutical preparations
CA2247270A1 (en) 1996-02-26 1997-08-28 Daiichi Pharmaceutical Co., Ltd. Liposome and liposome dispersion
DK0850646T3 (en) 1996-06-18 2008-05-13 Kyowa Hakko Kogyo Kk Liposome preparations of indolocarbazole derivatives
JP4368513B2 (en) 1999-12-27 2009-11-18 富士フイルム株式会社 Image processing method and apparatus, and recording medium
JP3415131B1 (en) * 2002-06-03 2003-06-09 メビオファーム株式会社 Liposome preparation
US20040022842A1 (en) * 2002-06-03 2004-02-05 Mebiopharm Co., Ltd. Liposome preparations containing oxaliplatin
US20040002284A1 (en) * 2002-06-27 2004-01-01 Leal Jose E. Illuminated throwing toy
CN100471493C (en) * 2003-12-17 2009-03-25 梅比欧法姆股份有限公司 Liposome preparation containing Oxaliplatin
LT3173073T (en) * 2004-05-03 2025-01-10 Ipsen Biopharm Ltd. Liposomes for drug delivery
JP2006248978A (en) * 2005-03-10 2006-09-21 Mebiopharm Co Ltd New liposome preparation
US8078919B2 (en) * 2005-06-14 2011-12-13 Hitachi Global Storage Technologies Netherlands B.V. Method, apparatus and program storage device for managing multiple step processes triggered by a signal
GR20060100144A (en) * 2006-03-03 2007-10-17 Cancer treatment using oxaliplatin encapsulated into liposomes and co-encapsulation into the liposome particle of more than one pharmaceutical preparations, or genes
WO2008030818A2 (en) * 2006-09-05 2008-03-13 Mebiopharm Co., Ltd. Novel liposome compositions
TWI468188B (en) 2008-01-30 2015-01-11 Univ Tokushima Anti-cancer effect enhancers consisting of oxaliplatin liposomal preparations and anticancer agents comprising the formulation
EP2123258A1 (en) * 2008-05-23 2009-11-25 Liplasome Pharma A/S Liposomes for drug delivery

Also Published As

Publication number Publication date
JP6230538B2 (en) 2017-11-15
US20190321294A1 (en) 2019-10-24
CN104703594B (en) 2018-01-23
JPWO2014025042A1 (en) 2016-07-25
EP2883542A1 (en) 2015-06-17
US20150216801A1 (en) 2015-08-06
US10383822B2 (en) 2019-08-20
US10993913B2 (en) 2021-05-04
HK1210035A1 (en) 2016-04-15
SG11201501010QA (en) 2015-04-29
WO2014025042A1 (en) 2014-02-13
ES2733061T3 (en) 2019-11-27
CN104703594A (en) 2015-06-10
EP2883542B1 (en) 2019-05-01
EP2883542A4 (en) 2016-01-06

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