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SG10201606981QA - 18f-saccharide-folates - Google Patents

18f-saccharide-folates

Info

Publication number
SG10201606981QA
SG10201606981QA SG10201606981QA SG10201606981QA SG10201606981QA SG 10201606981Q A SG10201606981Q A SG 10201606981QA SG 10201606981Q A SG10201606981Q A SG 10201606981QA SG 10201606981Q A SG10201606981Q A SG 10201606981QA SG 10201606981Q A SG10201606981Q A SG 10201606981QA
Authority
SG
Singapore
Prior art keywords
folates
saccharide
Prior art date
Application number
SG10201606981QA
Inventor
Roger Schibli
Rudolf Moser
Cristina Magdalena Müller
Simon Mensah Ametamey
Cindy Ramona Fischer
Viola Groehn
Original Assignee
Merck & Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Cie filed Critical Merck & Cie
Publication of SG10201606981QA publication Critical patent/SG10201606981QA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0491Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/005Sugars; Derivatives thereof; Nucleosides; Nucleotides; Nucleic acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/60Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Food Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Optics & Photonics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nuclear Medicine (AREA)
SG10201606981QA 2011-08-22 2012-08-21 18f-saccharide-folates SG10201606981QA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP11178260 2011-08-22

Publications (1)

Publication Number Publication Date
SG10201606981QA true SG10201606981QA (en) 2016-10-28

Family

ID=46704677

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201606981QA SG10201606981QA (en) 2011-08-22 2012-08-21 18f-saccharide-folates
SG2014001085A SG2014001085A (en) 2011-08-22 2012-08-21 18f-saccharide-folates

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG2014001085A SG2014001085A (en) 2011-08-22 2012-08-21 18f-saccharide-folates

Country Status (17)

Country Link
US (2) US10322195B2 (en)
EP (1) EP2776382B1 (en)
JP (1) JP6161209B2 (en)
KR (1) KR101994327B1 (en)
CN (1) CN103732563B (en)
AU (2) AU2012298546A1 (en)
CA (1) CA2839654C (en)
DK (1) DK2776382T3 (en)
EA (1) EA201400253A1 (en)
ES (1) ES2703107T3 (en)
IL (1) IL230760A (en)
PL (1) PL2776382T3 (en)
PT (1) PT2776382T (en)
SG (2) SG10201606981QA (en)
TR (1) TR201819447T4 (en)
WO (1) WO2013026842A1 (en)
ZA (1) ZA201400175B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10029995B2 (en) 2015-09-03 2018-07-24 Forma Therapeutics, Inc. [6,6] fused bicyclic HDAC8 inhibitors
TWI732825B (en) * 2016-05-20 2021-07-11 日商王子控股股份有限公司 Oriented self-assembly composition for pattern formation, monomer for orientation self-assembly composition for pattern formation, and pattern formation method
CN109232690A (en) * 2018-09-10 2019-01-18 南方医科大学南方医院 A kind of pet imaging agent standard items precursor and preparation method thereof
EP3671511B1 (en) 2018-12-19 2022-07-06 Rohde & Schwarz GmbH & Co. KG Communication system and method
CN111714640B (en) * 2019-03-14 2023-02-14 北京和益源生物技术有限公司 Nano carrier particle prepared from sugar-modified folic acid derivative and application thereof
CN111748002B (en) * 2019-03-14 2022-03-29 北京和益源生物技术有限公司 Deoxyglucose modified folic acid derivative and synthesis and application thereof

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4276280A (en) 1976-09-29 1981-06-30 Becton, Dickinson And Company Radiolabeled derivatives of folic acid
US4628090A (en) 1984-08-21 1986-12-09 Rensselaer Polytechnic Institute Fluorine-containing antifolates incapable of polyglutanayte formation related compounds
US6093382A (en) * 1998-05-16 2000-07-25 Bracco Research Usa Inc. Metal complexes derivatized with folate for use in diagnostic and therapeutic applications
EP2226316B1 (en) 2002-05-30 2016-01-13 The Scripps Research Institute Copper-catalysed ligation of azides and acetylenes
EP2452695A3 (en) 2004-12-23 2013-01-23 Purdue Research Foundation Positron emission tomography imaging method
US20060263293A1 (en) 2005-04-27 2006-11-23 Hartmuth Kolb Click chemistry method for synthesizing molecular imaging probes
EP1940841B9 (en) * 2005-10-07 2017-04-19 Guerbet Compounds comprising a biological target recognizing part, coupled to a signal part capable of complexing gallium
JP5869205B2 (en) 2007-02-07 2016-02-24 パーデュー・リサーチ・ファウンデーションPurdue Research Foundation Positron emission tomography
PL2150514T3 (en) * 2007-04-11 2019-05-31 Merck & Cie 18f-labelled folates
PT2146944E (en) 2007-04-11 2014-03-11 Merck & Cie A method for the preparation of 18f-labelled folates
AU2008237932C1 (en) * 2007-04-11 2014-04-24 Merck & Cie 18 F-labelled folates
JP5597396B2 (en) * 2007-09-28 2014-10-01 ナノデックス株式会社 Folic acid-modified cyclodextrin compound, method for producing the same, drug delivery agent for targeted drug delivery system, pharmaceutical composition and contrast agent
CA2736861C (en) * 2008-10-10 2017-11-14 Roger Schibli 18f-labelled folates as pet radiotracers
CA2839647C (en) * 2011-08-17 2022-08-16 Merck & Cie Folate conjugates of albumin-binding entities

Also Published As

Publication number Publication date
PT2776382T (en) 2018-12-24
JP6161209B2 (en) 2017-07-12
JP2014531411A (en) 2014-11-27
US10973936B2 (en) 2021-04-13
IL230760A (en) 2017-08-31
AU2017203512A1 (en) 2017-06-15
ES2703107T3 (en) 2019-03-07
CA2839654C (en) 2021-02-16
AU2012298546A1 (en) 2014-02-20
US20140193337A1 (en) 2014-07-10
SG2014001085A (en) 2014-03-28
EA201400253A1 (en) 2014-08-29
DK2776382T3 (en) 2019-01-14
US20190255200A1 (en) 2019-08-22
IL230760A0 (en) 2014-03-31
TR201819447T4 (en) 2019-01-21
EP2776382A1 (en) 2014-09-17
CN103732563A (en) 2014-04-16
CN103732563B (en) 2016-04-20
KR101994327B1 (en) 2019-06-28
PL2776382T3 (en) 2019-05-31
HK1194355A1 (en) 2014-10-17
WO2013026842A1 (en) 2013-02-28
EP2776382B1 (en) 2018-09-19
AU2017203512B2 (en) 2019-02-28
KR20140054284A (en) 2014-05-08
CA2839654A1 (en) 2013-02-28
ZA201400175B (en) 2015-08-26
US10322195B2 (en) 2019-06-18

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