SG10201603962TA - Anti-kir antibodies for the treatment of inflammatory disorders - Google Patents
Anti-kir antibodies for the treatment of inflammatory disordersInfo
- Publication number
- SG10201603962TA SG10201603962TA SG10201603962TA SG10201603962TA SG10201603962TA SG 10201603962T A SG10201603962T A SG 10201603962TA SG 10201603962T A SG10201603962T A SG 10201603962TA SG 10201603962T A SG10201603962T A SG 10201603962TA SG 10201603962T A SG10201603962T A SG 10201603962TA
- Authority
- SG
- Singapore
- Prior art keywords
- treatment
- inflammatory disorders
- kir antibodies
- kir
- antibodies
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161489806P | 2011-05-25 | 2011-05-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG10201603962TA true SG10201603962TA (en) | 2016-07-28 |
Family
ID=46785768
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201603962TA SG10201603962TA (en) | 2011-05-25 | 2012-05-25 | Anti-kir antibodies for the treatment of inflammatory disorders |
| SG2013086137A SG195082A1 (en) | 2011-05-25 | 2012-05-25 | Anti-kir antibodies for the treatment of inflammatory disorders |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2013086137A SG195082A1 (en) | 2011-05-25 | 2012-05-25 | Anti-kir antibodies for the treatment of inflammatory disorders |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US9067997B2 (en) |
| EP (1) | EP2714741B1 (en) |
| JP (1) | JP6342325B2 (en) |
| KR (1) | KR102046666B1 (en) |
| CN (1) | CN103717619B (en) |
| AR (1) | AR086582A1 (en) |
| AU (1) | AU2012260601B2 (en) |
| BR (1) | BR112013030017A2 (en) |
| CA (1) | CA2837184C (en) |
| EA (1) | EA036545B1 (en) |
| ES (1) | ES2765874T3 (en) |
| IL (1) | IL229582B (en) |
| MX (1) | MX347514B (en) |
| SG (2) | SG10201603962TA (en) |
| TW (1) | TWI560200B (en) |
| WO (1) | WO2012160448A2 (en) |
Families Citing this family (118)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090191213A9 (en) * | 2003-07-02 | 2009-07-30 | Novo Nordisk A/S | Compositions and methods for regulating NK cell activity |
| KR101325023B1 (en) * | 2003-07-02 | 2013-11-04 | 노보 노르디스크 에이/에스 | Compositions and methods for regulating nk cell activity |
| EP2287195B1 (en) * | 2004-07-01 | 2019-05-15 | Novo Nordisk A/S | Pan-kir2dl nk-receptor antibodies and their use in diagnostik and therapy |
| US20090196850A1 (en) * | 2005-01-06 | 2009-08-06 | Novo Nordisk A/S | Anti-Kir Combination Treatments and Methods |
| ES2579768T3 (en) | 2007-01-11 | 2016-08-16 | Novo Nordisk A/S | Anti-KIR antibodies, formulations and uses thereof |
| FI4122383T3 (en) | 2010-05-08 | 2025-05-19 | Univ California | Sem scanner sensing apparatus for early detection of ulcers |
| EP3263601B1 (en) * | 2012-10-02 | 2021-11-24 | Bristol-Myers Squibb Company | Combination of anti-kir antibodies and anti-pd-1 antibodies to treat cancer |
| GB201304662D0 (en) * | 2013-03-14 | 2013-05-01 | Sigmoid Pharma Ltd | Compositions |
| ES2707057T3 (en) | 2013-11-06 | 2019-04-02 | Bristol Myers Squibb Co | Combination of anti-KIR and anti-CS1 antibodies to treat multiple myeloma |
| US9622483B2 (en) | 2014-02-19 | 2017-04-18 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| US11039620B2 (en) | 2014-02-19 | 2021-06-22 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| US11039621B2 (en) | 2014-02-19 | 2021-06-22 | Corning Incorporated | Antimicrobial glass compositions, glasses and polymeric articles incorporating the same |
| DK3116908T3 (en) * | 2014-03-14 | 2019-10-07 | Innate Pharma | HUMANIZED KIR3DL2 ANTIBODIES |
| WO2016030488A1 (en) * | 2014-08-27 | 2016-03-03 | Innate Pharma | Treatment of celiac disease |
| US20160272709A1 (en) * | 2015-02-12 | 2016-09-22 | The Regents Of The University Of Michigan | Anti-kir antibodies |
| HUE056775T2 (en) * | 2015-03-09 | 2022-03-28 | Argenx Bvba | Methods of reducing serum levels of fc-containing agents using fcrn antagonsits |
| DK3283107T3 (en) | 2015-04-17 | 2020-08-31 | Bristol Myers Squibb Co | COMPOSITIONS INCLUDING A COMBINATION OF IPILIMUMAB AND NIVOLUMAB |
| CN107847445B (en) * | 2015-04-20 | 2021-07-20 | 加利福尼亚大学董事会 | Encapsulated gas or partial vacuum CT contrast material |
| NZ736278A (en) | 2015-04-24 | 2022-05-27 | Bruin Biometrics Llc | Apparatus and methods for determining damaged tissue using sub-epidermal moisture measurements |
| JP6644478B2 (en) * | 2015-04-28 | 2020-02-12 | 国立大学法人東北大学 | Method for determining the risk of side effects from thiopurine preparations |
| EP4545082A3 (en) | 2015-05-06 | 2025-07-02 | SNIPR Technologies Limited | Altering microbial populations & modifying microbiota |
| BR112017024899A2 (en) | 2015-05-21 | 2018-11-13 | Harpoon Therapeutics, Inc. | trispecific binding proteins and methods of use. |
| KR102733066B1 (en) | 2015-06-26 | 2024-11-21 | 주식회사 파마리서치 | Composition comprising mixture of DNA fragments separated from fish's semen or testis for the prevention or treatment of ischemic colitis |
| WO2016208880A1 (en) * | 2015-06-26 | 2016-12-29 | 주식회사 파마리서치프로덕트 | Composition for preventing or treating ischemic enteritis containing dna fragment mixture isolated from sperm or testis of fish |
| AU2016291817A1 (en) | 2015-07-16 | 2018-02-22 | Biolinerx Ltd. | Compositions and methods for treating cancer |
| WO2017016805A1 (en) | 2015-07-24 | 2017-02-02 | Innate Pharma | Methods for detecting tissue infiltrating nk cells |
| JP2018532810A (en) | 2015-11-07 | 2018-11-08 | マルチビア インコーポレイテッド | Composition comprising tumor suppressor gene therapy and immune checkpoint therapy for the treatment of cancer |
| CN108495655A (en) * | 2015-12-15 | 2018-09-04 | 纪念斯隆凯特琳癌症中心 | For tissue division for example for visual imaging system and method in art |
| JP7082943B2 (en) | 2016-02-16 | 2022-06-09 | 一般社団法人ファルマバレープロジェクト支援機構 | Immunosuppressive release agent and its use |
| US11643459B2 (en) | 2016-03-11 | 2023-05-09 | Scholar Rock, Inc. | TGFβ1-binding immunoglobulins and use thereof |
| EP3439688A4 (en) * | 2016-04-04 | 2020-05-27 | The Regents of the University of California | COMPOSITIONS AND METHODS IN CONNECTION WITH POLYCYTOTOXIC T CELLS |
| US11623958B2 (en) | 2016-05-20 | 2023-04-11 | Harpoon Therapeutics, Inc. | Single chain variable fragment CD3 binding proteins |
| CA3025019A1 (en) | 2016-05-20 | 2017-11-23 | Biohaven Pharmaceutical Holding Company Ltd. | Use of glutamate modulating agents with immunotherapies to treat cancer |
| GB201609811D0 (en) | 2016-06-05 | 2016-07-20 | Snipr Technologies Ltd | Methods, cells, systems, arrays, RNA and kits |
| CN105943048B (en) * | 2016-06-27 | 2018-11-13 | 首都医科大学附属北京胸科医院 | A kind of method and its application for distinguishing tubercular meningitis and viral meningitis based on nuclear magnetic resonance technique |
| US10858431B2 (en) * | 2016-06-30 | 2020-12-08 | Trellis Bioscience, Llc | Monoclonal antibodies targeting killer immunoglobulin-like receptor (KIR) family signaling |
| MX2019003447A (en) | 2016-09-27 | 2019-08-29 | Univ Texas | Methods for enhancing immune checkpoint blockade therapy by modulating the microbiome. |
| SG11201903283UA (en) | 2016-10-12 | 2019-05-30 | Univ Texas | Methods and compositions for tusc2 immunotherapy |
| CN110381997A (en) | 2016-12-12 | 2019-10-25 | 茂体外尔公司 | For treating and preventing the method and composition comprising gene-virus therapy and immunologic test point inhibitor of cancer and infectious diseases |
| MX2019004926A (en) | 2017-02-03 | 2019-06-20 | Bruin Biometrics Llc | Measurement of edema. |
| US11304652B2 (en) | 2017-02-03 | 2022-04-19 | Bbi Medical Innovations, Llc | Measurement of tissue viability |
| CN118177725A (en) | 2017-02-03 | 2024-06-14 | 布鲁恩医疗创新有限责任公司 | Measurement of susceptibility to diabetic foot ulcers |
| CA3058175A1 (en) | 2017-03-31 | 2018-10-04 | Bristol-Myers Squibb Company | Methods of treating tumor |
| CA3063359A1 (en) | 2017-05-12 | 2018-11-15 | Harpoon Therapeutics, Inc. | Mesothelin binding proteins |
| KR102425983B1 (en) | 2017-10-13 | 2022-07-29 | 하푼 테라퓨틱스, 인크. | Trispecific Proteins and Methods of Use |
| IL315737A (en) | 2017-10-13 | 2024-11-01 | Harpoon Therapeutics Inc | B cell maturation antigen binding proteins |
| CN111247169A (en) | 2017-10-15 | 2020-06-05 | 百时美施贵宝公司 | Method for treating tumors |
| GB2574945A (en) | 2017-11-16 | 2019-12-25 | Bruin Biometrics Llc | Providing a continuity of care across multiple care settings |
| JP7420720B2 (en) * | 2017-12-13 | 2024-01-23 | モメンタ ファーマシューティカルズ インコーポレイテッド | FcRn antibodies and their use |
| EP4331480B1 (en) | 2018-02-09 | 2025-07-30 | Bruin Biometrics, LLC | Detection of tissue damage |
| CA3094329A1 (en) | 2018-03-19 | 2020-02-20 | Multivir Inc. | Methods and compositions comprising tumor suppressor gene therapy and cd122/cd132 agonists for the treatment of cancer |
| US11242393B2 (en) | 2018-03-23 | 2022-02-08 | Bristol-Myers Squibb Company | Antibodies against MICA and/or MICB and uses thereof |
| WO2019185551A1 (en) | 2018-03-25 | 2019-10-03 | Snipr Biome Aps. | Treating & preventing microbial infections |
| US10760075B2 (en) | 2018-04-30 | 2020-09-01 | Snipr Biome Aps | Treating and preventing microbial infections |
| WO2019191676A1 (en) | 2018-03-30 | 2019-10-03 | Bristol-Myers Squibb Company | Methods of treating tumor |
| US20210251994A1 (en) | 2018-06-15 | 2021-08-19 | Flagship Pioneering Innovations V, Inc. | Increasing immune activity through modulation of postcellular signaling factors |
| CR20210076A (en) | 2018-07-20 | 2021-09-02 | Momenta Pharmaceuticals Inc | FCRN ANTIBODY COMPOSITIONS |
| JP7505780B2 (en) * | 2018-08-13 | 2024-06-25 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | Treatment of amyotrophic lateral sclerosis |
| CN120535649A (en) | 2018-08-30 | 2025-08-26 | 免疫生物公司 | Single-chain chimeric polypeptides and uses thereof |
| WO2020047462A2 (en) | 2018-08-30 | 2020-03-05 | HCW Biologics, Inc. | Methods of treating aging-related disorders |
| CA3108949A1 (en) | 2018-08-30 | 2020-03-05 | HCW Biologics, Inc. | Multi-chain chimeric polypeptides and uses thereof |
| US12195544B2 (en) | 2018-09-21 | 2025-01-14 | Harpoon Therapeutics, Inc. | EGFR binding proteins and methods of use |
| EP3856771A4 (en) | 2018-09-25 | 2022-06-29 | Harpoon Therapeutics, Inc. | Dll3 binding proteins and methods of use |
| KR102903190B1 (en) | 2018-10-11 | 2025-12-23 | 브루인 바이오메트릭스, 엘엘씨 | Devices with disposable elements |
| CA3118182A1 (en) | 2018-12-21 | 2020-06-25 | Onxeo | New conjugated nucleic acid molecules and their uses |
| CN109675037B (en) * | 2019-01-25 | 2021-09-14 | 南方医科大学 | Application of ATP and receptor thereof in preparation of drugs for treating autism |
| MA55805A (en) | 2019-05-03 | 2022-03-09 | Flagship Pioneering Innovations V Inc | METHODS OF MODULATING IMMUNE ACTIVITY |
| KR20220016157A (en) | 2019-05-30 | 2022-02-08 | 브리스톨-마이어스 스큅 컴퍼니 | Cell localization signatures and combination therapies |
| EP3976832A1 (en) | 2019-05-30 | 2022-04-06 | Bristol-Myers Squibb Company | Methods of identifying a subject suitable for an immuno-oncology (i-o) therapy |
| JP2022534967A (en) | 2019-05-30 | 2022-08-04 | ブリストル-マイヤーズ スクイブ カンパニー | Multiple tumor gene signatures and their uses |
| CN114269903B (en) | 2019-06-21 | 2025-11-25 | 免疫生物公司 | Multi-chain chimeric peptides and their uses |
| WO2021024020A1 (en) | 2019-08-06 | 2021-02-11 | Astellas Pharma Inc. | Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer |
| US11851490B2 (en) * | 2019-08-15 | 2023-12-26 | Northwestern University | Methods and compositions for treating, inhibiting, and/or preventing heterotopic ossification |
| CN112574281B (en) * | 2019-09-27 | 2022-03-29 | 暨南大学 | Paired immunoglobulin-like receptor B binding peptide, derivative and application thereof |
| WO2021113644A1 (en) | 2019-12-05 | 2021-06-10 | Multivir Inc. | Combinations comprising a cd8+ t cell enhancer, an immune checkpoint inhibitor and radiotherapy for targeted and abscopal effects for the treatment of cancer |
| EP4076434A1 (en) | 2019-12-17 | 2022-10-26 | Flagship Pioneering Innovations V, Inc. | Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly |
| US12403175B2 (en) | 2020-01-08 | 2025-09-02 | argenx BV | Methods for treating pemphigus disorders |
| EP4103600A1 (en) | 2020-02-11 | 2022-12-21 | HCW Biologics, Inc. | Chromatography resin and uses thereof |
| KR20220140572A (en) | 2020-02-11 | 2022-10-18 | 에이치씨더블유 바이올로직스, 인크. | How to Activate Regulatory T Cells |
| JP2023513573A (en) | 2020-02-11 | 2023-03-31 | エイチシーダブリュー バイオロジックス インコーポレイテッド | Methods of treating age-related and inflammatory diseases |
| US12497462B2 (en) | 2020-04-29 | 2025-12-16 | Immunitybio, Inc. | Anti-CD26 proteins and uses thereof |
| AU2021283199A1 (en) | 2020-06-01 | 2023-01-05 | Immunitybio, Inc. | Methods of treating aging-related disorders |
| US12024545B2 (en) | 2020-06-01 | 2024-07-02 | HCW Biologics, Inc. | Methods of treating aging-related disorders |
| WO2021247003A1 (en) | 2020-06-01 | 2021-12-09 | HCW Biologics, Inc. | Methods of treating aging-related disorders |
| TW202214857A (en) | 2020-06-19 | 2022-04-16 | 法商昂席歐公司 | New conjugated nucleic acid molecules and their uses |
| CN116096906A (en) | 2020-06-29 | 2023-05-09 | 旗舰创业创新五公司 | Virus engineered to promote saenox delivery and use thereof in treating cancer |
| US20250262293A1 (en) | 2020-07-07 | 2025-08-21 | BioNTech SE | Therapeutic rna for hpv-positive cancer |
| US20230303700A1 (en) | 2020-08-31 | 2023-09-28 | Bristol-Myers Squibb Company | Cell localization signature and immunotherapy |
| WO2022120179A1 (en) | 2020-12-03 | 2022-06-09 | Bristol-Myers Squibb Company | Multi-tumor gene signatures and uses thereof |
| TW202245808A (en) | 2020-12-21 | 2022-12-01 | 德商拜恩迪克公司 | Therapeutic rna for treating cancer |
| WO2022135667A1 (en) | 2020-12-21 | 2022-06-30 | BioNTech SE | Therapeutic rna for treating cancer |
| WO2022135666A1 (en) | 2020-12-21 | 2022-06-30 | BioNTech SE | Treatment schedule for cytokine proteins |
| MX2023007650A (en) | 2020-12-28 | 2023-09-11 | Bristol Myers Squibb Co | Subcutaneous administration of pd1/pd-l1 antibodies. |
| MX2023007734A (en) | 2020-12-28 | 2023-08-21 | Bristol Myers Squibb Co | Antibody compositions and methods of use thereof. |
| US11642075B2 (en) | 2021-02-03 | 2023-05-09 | Bruin Biometrics, Llc | Methods of treating deep and early-stage pressure induced tissue damage |
| MX2023009100A (en) | 2021-02-03 | 2023-09-25 | Mozart Therapeutics Inc | Binding agents and methods of using the same. |
| CN115120620A (en) * | 2021-03-26 | 2022-09-30 | 上海雷允上药业有限公司 | Use of a kind of Liushen pill and pharmaceutical composition and use |
| JP2024512669A (en) | 2021-03-31 | 2024-03-19 | フラグシップ パイオニアリング イノベーションズ ブイ,インコーポレーテッド | Tanotransmission polypeptides and their use in the treatment of cancer |
| JP2024514530A (en) | 2021-04-02 | 2024-04-02 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Antibodies against truncated CDCP1 and uses thereof |
| CA3224374A1 (en) | 2021-06-29 | 2023-01-05 | Flagship Pioneering Innovations V, Inc. | Immune cells engineered to promote thanotransmission and uses thereof |
| CA3225254A1 (en) | 2021-07-13 | 2023-01-19 | BioNTech SE | Multispecific binding agents against cd40 and cd137 in combination therapy for cancer |
| TW202333802A (en) | 2021-10-11 | 2023-09-01 | 德商拜恩迪克公司 | Therapeutic rna for lung cancer |
| WO2023076876A1 (en) * | 2021-10-26 | 2023-05-04 | Mozart Therapeutics, Inc. | Modulation of immune responses to viral vectors |
| JP2025500922A (en) | 2021-12-16 | 2025-01-15 | ヴァレリオ・セラピューティクス | Novel conjugated nucleic acid molecules and uses thereof |
| WO2023178329A1 (en) | 2022-03-18 | 2023-09-21 | Bristol-Myers Squibb Company | Methods of isolating polypeptides |
| CA3258064A1 (en) | 2022-06-02 | 2023-12-07 | Bristol-Myers Squibb Company | Antibody compositions and methods of use thereof |
| WO2023242372A1 (en) | 2022-06-15 | 2023-12-21 | argenx BV | Fcrn/hsa binding molecules and methods of use |
| GB202209518D0 (en) | 2022-06-29 | 2022-08-10 | Snipr Biome Aps | Treating & preventing E coli infections |
| WO2024077191A1 (en) | 2022-10-05 | 2024-04-11 | Flagship Pioneering Innovations V, Inc. | Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer |
| IL321098A (en) | 2022-12-14 | 2025-07-01 | Astellas Pharma Europe Bv | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and immune checkpoint inhibitors |
| WO2024151687A1 (en) | 2023-01-09 | 2024-07-18 | Flagship Pioneering Innovations V, Inc. | Genetic switches and their use in treating cancer |
| WO2025038763A1 (en) | 2023-08-15 | 2025-02-20 | Bristol-Myers Squibb Company | Ceramic hydroxyapatite chromatography flow through method |
| CN117031044B (en) * | 2023-10-07 | 2024-01-02 | 首都医科大学附属北京天坛医院 | Biomarker and kit for predicting stroke-related pneumonia and diagnosis equipment |
| TW202541837A (en) | 2023-12-08 | 2025-11-01 | 日商安斯泰來製藥公司 | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2 |
| WO2025120866A1 (en) | 2023-12-08 | 2025-06-12 | Astellas Pharma Inc. | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2 |
| WO2025120867A1 (en) | 2023-12-08 | 2025-06-12 | Astellas Pharma Inc. | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies |
| WO2025145207A1 (en) | 2023-12-29 | 2025-07-03 | Bristol-Myers Squibb Company | Combination therapy of kras inhibitor and treg-depleting agent |
| CN118987020B (en) * | 2024-08-23 | 2025-09-05 | 天津医科大学 | Application of Auranofin in the preparation of drugs for mismatch repair-deficient tumors |
Family Cites Families (110)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
| US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
| US4517288A (en) | 1981-01-23 | 1985-05-14 | American Hospital Supply Corp. | Solid phase system for ligand assay |
| DE3134803A1 (en) | 1981-09-02 | 1983-03-17 | Brown, Boveri & Cie Ag, 6800 Mannheim | "METHOD FOR CLEANING SEMICONDUCTOR-COOLED ELECTRICAL MACHINES AND APPARATUS" |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US4699880A (en) | 1984-09-25 | 1987-10-13 | Immunomedics, Inc. | Method of producing monoclonal anti-idiotype antibody |
| JPS61134325A (en) | 1984-12-04 | 1986-06-21 | Teijin Ltd | Expression of hybrid antibody gene |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| CA1291031C (en) | 1985-12-23 | 1991-10-22 | Nikolaas C.J. De Jaeger | Method for the detection of specific binding agents and their correspondingbindable substances |
| US6548640B1 (en) | 1986-03-27 | 2003-04-15 | Btg International Limited | Altered antibodies |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| DE122007000007I1 (en) | 1986-04-09 | 2007-05-16 | Genzyme Corp | Genetically transformed animals secreting a desired protein in milk |
| US4902505A (en) | 1986-07-30 | 1990-02-20 | Alkermes | Chimeric peptides for neuropeptide delivery through the blood-brain barrier |
| US4987071A (en) | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
| US5116742A (en) | 1986-12-03 | 1992-05-26 | University Patents, Inc. | RNA ribozyme restriction endoribonucleases and methods |
| WO1988007089A1 (en) | 1987-03-18 | 1988-09-22 | Medical Research Council | Altered antibodies |
| US4904582A (en) | 1987-06-11 | 1990-02-27 | Synthetic Genetics | Novel amphiphilic nucleic acid conjugates |
| US4873316A (en) | 1987-06-23 | 1989-10-10 | Biogen, Inc. | Isolation of exogenous recombinant proteins from the milk of transgenic mammals |
| US5080891A (en) | 1987-08-03 | 1992-01-14 | Ddi Pharmaceuticals, Inc. | Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols |
| US5677425A (en) | 1987-09-04 | 1997-10-14 | Celltech Therapeutics Limited | Recombinant antibody |
| US5476996A (en) | 1988-06-14 | 1995-12-19 | Lidak Pharmaceuticals | Human immune system in non-human animal |
| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
| GB8823869D0 (en) | 1988-10-12 | 1988-11-16 | Medical Res Council | Production of antibodies |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5116964A (en) | 1989-02-23 | 1992-05-26 | Genentech, Inc. | Hybrid immunoglobulins |
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| US6153737A (en) | 1990-01-11 | 2000-11-28 | Isis Pharmaceuticals, Inc. | Derivatized oligonucleotides having improved uptake and other properties |
| US6075181A (en) | 1990-01-12 | 2000-06-13 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| DK0463151T3 (en) | 1990-01-12 | 1996-07-01 | Cell Genesys Inc | Generation of xenogenic antibodies |
| US6150584A (en) | 1990-01-12 | 2000-11-21 | Abgenix, Inc. | Human antibodies derived from immunized xenomice |
| US6673986B1 (en) | 1990-01-12 | 2004-01-06 | Abgenix, Inc. | Generation of xenogeneic antibodies |
| US5521288A (en) | 1990-03-26 | 1996-05-28 | Bristol-Myers Squibb Company | CD28IG fusion protein |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| US6172197B1 (en) | 1991-07-10 | 2001-01-09 | Medical Research Council | Methods for producing members of specific binding pairs |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US6255458B1 (en) | 1990-08-29 | 2001-07-03 | Genpharm International | High affinity human antibodies and human antibodies against digoxin |
| US6300129B1 (en) | 1990-08-29 | 2001-10-09 | Genpharm International | Transgenic non-human animals for producing heterologous antibodies |
| US5877397A (en) | 1990-08-29 | 1999-03-02 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| JP2938569B2 (en) | 1990-08-29 | 1999-08-23 | ジェンファーム インターナショナル,インコーポレイティド | Method for producing xenogeneic immunoglobulin and transgenic mouse |
| US5789650A (en) | 1990-08-29 | 1998-08-04 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| WO1993012227A1 (en) | 1991-12-17 | 1993-06-24 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5874299A (en) | 1990-08-29 | 1999-02-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| WO1994004679A1 (en) | 1991-06-14 | 1994-03-03 | Genentech, Inc. | Method for making humanized antibodies |
| JP4124480B2 (en) | 1991-06-14 | 2008-07-23 | ジェネンテック・インコーポレーテッド | Immunoglobulin variants |
| US5844095A (en) | 1991-06-27 | 1998-12-01 | Bristol-Myers Squibb Company | CTLA4 Ig fusion proteins |
| US6335434B1 (en) | 1998-06-16 | 2002-01-01 | Isis Pharmaceuticals, Inc., | Nucleosidic and non-nucleosidic folate conjugates |
| DE69233782D1 (en) | 1991-12-02 | 2010-05-20 | Medical Res Council | Preparation of Autoantibodies on Phage Surfaces Starting from Antibody Segment Libraries |
| US5660827A (en) | 1992-03-05 | 1997-08-26 | Board Of Regents, The University Of Texas System | Antibodies that bind to endoglin |
| US5714350A (en) | 1992-03-09 | 1998-02-03 | Protein Design Labs, Inc. | Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region |
| AU4116793A (en) | 1992-04-24 | 1993-11-29 | Board Of Regents, The University Of Texas System | Recombinant production of immunoglobulin-like domains in prokaryotic cells |
| US6172208B1 (en) | 1992-07-06 | 2001-01-09 | Genzyme Corporation | Oligonucleotides modified with conjugate groups |
| DE69333366T2 (en) | 1992-10-30 | 2004-09-16 | The General Hospital Corp., Boston | A NEW CELL CYCLE CONTROL PROTEIN |
| AU6445894A (en) | 1993-03-19 | 1994-10-11 | Duke University | Method of treatment of tumors with an antibody binding to tenascin |
| CA2161351C (en) | 1993-04-26 | 2010-12-21 | Nils Lonberg | Transgenic non-human animals capable of producing heterologous antibodies |
| DE69433036T2 (en) | 1993-09-03 | 2004-05-27 | Isis Pharmaceuticals, Inc., Carlsbad | AMINODERIVATIZED NUCLEOSIDES AND OLIGONUCLEOSIDES |
| ATE306930T1 (en) | 1994-08-12 | 2005-11-15 | Immunomedics Inc | IMMUNE CONJUGATES AND HUMAN ANTIBODIES SPECIFIC FOR B-CELL LYMPHOMA AND LEUKEMIA CELLS |
| US5801155A (en) | 1995-04-03 | 1998-09-01 | Epoch Pharmaceuticals, Inc. | Covalently linked oligonucleotide minor grove binder conjugates |
| US5869046A (en) | 1995-04-14 | 1999-02-09 | Genentech, Inc. | Altered polypeptides with increased half-life |
| US6121022A (en) | 1995-04-14 | 2000-09-19 | Genentech, Inc. | Altered polypeptides with increased half-life |
| US5789244A (en) | 1996-01-08 | 1998-08-04 | Canji, Inc. | Compositions and methods for the treatment of cancer using recombinant viral vector delivery systems |
| US6750334B1 (en) | 1996-02-02 | 2004-06-15 | Repligen Corporation | CTLA4-immunoglobulin fusion proteins having modified effector functions and uses therefor |
| US6444806B1 (en) | 1996-04-30 | 2002-09-03 | Hisamitsu Pharmaceutical Co., Inc. | Conjugates and methods of forming conjugates of oligonucleotides and carbohydrates |
| US6653104B2 (en) | 1996-10-17 | 2003-11-25 | Immunomedics, Inc. | Immunotoxins, comprising an internalizing antibody, directed against malignant and normal cells |
| US20040038894A1 (en) | 1996-12-31 | 2004-02-26 | Institut National De La Sante Et De La Recherche Medicale (I.N.S.E.R.M.) | Compounds for modulating cell negative regulations and biological applications thereof |
| US6277375B1 (en) | 1997-03-03 | 2001-08-21 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| PT1071700E (en) | 1998-04-20 | 2010-04-23 | Glycart Biotechnology Ag | Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity |
| US6300319B1 (en) | 1998-06-16 | 2001-10-09 | Isis Pharmaceuticals, Inc. | Targeted oligonucleotide conjugates |
| US6383778B1 (en) | 1998-07-28 | 2002-05-07 | The Regents Of The University Of California | Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction |
| US6335437B1 (en) | 1998-09-07 | 2002-01-01 | Isis Pharmaceuticals, Inc. | Methods for the preparation of conjugated oligomers |
| US6225289B1 (en) | 1998-12-10 | 2001-05-01 | Genvec, Inc. | Methods and compositions for preserving adenoviral vectors |
| ES2601882T5 (en) | 1999-04-09 | 2021-06-07 | Kyowa Kirin Co Ltd | Procedure to monitor the activity of an immunofunctional molecule |
| US6696686B1 (en) | 1999-06-06 | 2004-02-24 | Elgems Ltd. | SPECT for breast cancer detection |
| ATE354655T1 (en) | 1999-08-24 | 2007-03-15 | Medarex Inc | HUMAN ANTIBODIES TO CTLA-4 AND THEIR USES |
| US6395437B1 (en) | 1999-10-29 | 2002-05-28 | Advanced Micro Devices, Inc. | Junction profiling using a scanning voltage micrograph |
| US6559279B1 (en) | 2000-09-08 | 2003-05-06 | Isis Pharmaceuticals, Inc. | Process for preparing peptide derivatized oligomeric compounds |
| EP1916303B1 (en) | 2000-11-30 | 2013-02-27 | Medarex, Inc. | Nucleic acids encoding rearranged human immunoglobulin sequences from transgenic transchromosomal mice |
| ATE446771T1 (en) | 2001-05-24 | 2009-11-15 | Zymogenetics Inc | TACI-IMMUNOGLOBULIN FUSION PROTEINS |
| US6905827B2 (en) * | 2001-06-08 | 2005-06-14 | Expression Diagnostics, Inc. | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases |
| US20030031671A1 (en) | 2001-08-01 | 2003-02-13 | Sydney Welt | Methods of treating colon cancer utilizing tumor-specific antibodies |
| HUP0600342A3 (en) | 2001-10-25 | 2011-03-28 | Genentech Inc | Glycoprotein compositions |
| WO2003048185A2 (en) | 2001-11-30 | 2003-06-12 | Genvec, Inc. | Angiopioetin related factors |
| CN102911987B (en) | 2002-04-09 | 2015-09-30 | 协和发酵麒麟株式会社 | The adorned cell of genome |
| AU2003294930B2 (en) | 2002-12-23 | 2008-12-04 | Innate Pharma | Pharmaceutical compositions having an effect on the proliferation of NK cells and a method using the same |
| KR101325023B1 (en) * | 2003-07-02 | 2013-11-04 | 노보 노르디스크 에이/에스 | Compositions and methods for regulating nk cell activity |
| SI1639013T1 (en) * | 2003-07-02 | 2013-01-31 | Innate Pharma | Pan-kir2dl NK-receptor antibodies and their use in diagnostic and therapy |
| CN104645327A (en) * | 2003-07-24 | 2015-05-27 | 依奈特制药公司 | Methods and compositions for increasing the efficiency of therapeutic antibodies using NK cell potentiating compounds |
| JP2007508332A (en) | 2003-10-17 | 2007-04-05 | ノボ ノルディスク アクティーゼルスカブ | Combination therapy |
| JP2007523099A (en) | 2004-02-20 | 2007-08-16 | ノボ ノルディスク アクティーゼルスカブ | Combination therapy |
| MXPA06013484A (en) * | 2004-05-21 | 2007-01-23 | Pfizer Prod Inc | Metabolites of (+)- (2s, 3s)-3- (2-methoxy-5- trifluoromethoxybenzylamino) -2-phenyl -piperidine. |
| EP2287195B1 (en) * | 2004-07-01 | 2019-05-15 | Novo Nordisk A/S | Pan-kir2dl nk-receptor antibodies and their use in diagnostik and therapy |
| DK1831258T4 (en) * | 2004-12-28 | 2023-08-28 | Innate Pharma Sa | Monoklonale antistoffer mod NKG2A |
| DK1835937T3 (en) * | 2005-01-06 | 2012-07-23 | Novo Nordisk As | Compositions and Methods for Treating Viral Infection |
| US20090196850A1 (en) | 2005-01-06 | 2009-08-06 | Novo Nordisk A/S | Anti-Kir Combination Treatments and Methods |
| PT1836225E (en) * | 2005-01-06 | 2012-01-10 | Novo Nordisk As | Kir-binding agents and methods of use thereof |
| EP2322557B1 (en) * | 2005-10-14 | 2017-08-30 | Innate Pharma | Compositions and methods for treating proliferative disorders |
| ES2579768T3 (en) * | 2007-01-11 | 2016-08-16 | Novo Nordisk A/S | Anti-KIR antibodies, formulations and uses thereof |
| EP2350318A4 (en) * | 2008-10-22 | 2012-04-18 | Univ Michigan | METHODS, COMPOSITIONS AND KITS FOR DIAGNOSING, MONITORING AND TREATING DISEASE |
| DK3184109T3 (en) * | 2009-12-29 | 2021-02-15 | Gamida Cell Ltd | PROCEDURES TO IMPROVE THE PROLIFERATION AND ACTIVITY OF NATURAL KILLER CELLS |
| EP3153521B1 (en) | 2010-03-26 | 2019-09-04 | Trustees of Dartmouth College | Vista regulatory t cell mediator protein, vista binding agents and use thereof |
| EA035033B1 (en) * | 2010-11-22 | 2020-04-20 | Иннейт Фарма Са | Method for treatment of hematological pre-malignancy or hematological malignancy |
| KR102009106B1 (en) * | 2018-01-11 | 2019-08-08 | 고려대학교 산학협력단 | Method for user authentication |
-
2012
- 2012-05-25 CA CA2837184A patent/CA2837184C/en active Active
- 2012-05-25 JP JP2014511973A patent/JP6342325B2/en active Active
- 2012-05-25 SG SG10201603962TA patent/SG10201603962TA/en unknown
- 2012-05-25 EA EA201391755A patent/EA036545B1/en not_active IP Right Cessation
- 2012-05-25 WO PCT/IB2012/001512 patent/WO2012160448A2/en not_active Ceased
- 2012-05-25 ES ES12753810T patent/ES2765874T3/en active Active
- 2012-05-25 KR KR1020137033948A patent/KR102046666B1/en not_active Expired - Fee Related
- 2012-05-25 MX MX2013013635A patent/MX347514B/en active IP Right Grant
- 2012-05-25 AU AU2012260601A patent/AU2012260601B2/en not_active Ceased
- 2012-05-25 US US13/481,161 patent/US9067997B2/en active Active
- 2012-05-25 BR BR112013030017-5A patent/BR112013030017A2/en not_active IP Right Cessation
- 2012-05-25 TW TW101118857A patent/TWI560200B/en not_active IP Right Cessation
- 2012-05-25 CN CN201280037229.1A patent/CN103717619B/en active Active
- 2012-05-25 EP EP12753810.6A patent/EP2714741B1/en active Active
- 2012-05-25 SG SG2013086137A patent/SG195082A1/en unknown
- 2012-05-28 AR ARP120101874A patent/AR086582A1/en unknown
-
2013
- 2013-11-24 IL IL229582A patent/IL229582B/en active IP Right Grant
-
2015
- 2015-06-29 US US14/753,886 patent/US20150376275A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012160448A3 (en) | 2013-05-10 |
| TWI560200B (en) | 2016-12-01 |
| AR086582A1 (en) | 2014-01-08 |
| KR102046666B1 (en) | 2019-11-19 |
| ES2765874T3 (en) | 2020-06-11 |
| US20150376275A1 (en) | 2015-12-31 |
| US9067997B2 (en) | 2015-06-30 |
| CA2837184C (en) | 2021-09-21 |
| AU2012260601B2 (en) | 2018-02-01 |
| WO2012160448A2 (en) | 2012-11-29 |
| MX2013013635A (en) | 2014-07-09 |
| AU2012260601A1 (en) | 2013-11-21 |
| MX347514B (en) | 2017-04-28 |
| CA2837184A1 (en) | 2012-11-29 |
| JP2014520092A (en) | 2014-08-21 |
| KR20140058445A (en) | 2014-05-14 |
| CN103717619A (en) | 2014-04-09 |
| EA036545B1 (en) | 2020-11-20 |
| EP2714741B1 (en) | 2019-10-30 |
| JP6342325B2 (en) | 2018-06-13 |
| EA201391755A1 (en) | 2014-08-29 |
| CN103717619B (en) | 2018-11-13 |
| US20120328615A1 (en) | 2012-12-27 |
| IL229582B (en) | 2020-06-30 |
| IL229582A0 (en) | 2014-01-30 |
| EP2714741A2 (en) | 2014-04-09 |
| TW201311723A (en) | 2013-03-16 |
| SG195082A1 (en) | 2013-12-30 |
| BR112013030017A2 (en) | 2020-10-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL229582A0 (en) | Anti-kir antibodies for the treatment of inflammatory disorders | |
| IL257581A (en) | Novel dihydropyrimidinoisoquinolinones and pharmaceutical compositions thereof for the treatment of inflammatory disorders | |
| ZA201307793B (en) | Novel compound useful for the treatment of degenerative and inflammatory diseases | |
| ZA201308111B (en) | Methods for the treatment of cancer and inflammatory diseases using cereblon as a predictor | |
| IL226401A0 (en) | Methods of treating fgf21-associated disorders | |
| ZA201305971B (en) | Method for the purification of biphephos | |
| GB2503852B (en) | Compounds for the treatment of neuropsychiatric disorders | |
| PL2809336T3 (en) | Factor xii inhibitors for the treatment of neurological inflammatory disorders | |
| ZA201305972B (en) | Method for the preparation of biphephos | |
| SG11201401202YA (en) | Antagonists of il17c for the treatment of inflammatory disorders | |
| ZA201208172B (en) | Methods for the treatment of il-1b related conditions | |
| IL233061A0 (en) | Recombinant human alpha-1-antitrypsin for the treatment of inflammatory disorders | |
| IL232190A0 (en) | Methods of treating inflammatory disorders using anti-m-csf antibodies | |
| IL229658A0 (en) | Scyllo-inositol for the treatment of behavioral and psychiatric disorders | |
| EP2758780A4 (en) | Method for the treatment of multiple sclerosis | |
| SG11201400405TA (en) | Caninised antibodies and method for the production of same | |
| ZA201207397B (en) | Process for the preparation of dexlansoprazole | |
| PT2691103T (en) | Method for treating disorders of the skin | |
| IL223385B (en) | Treatment of inflammatory disorders | |
| EP2780766A4 (en) | Devices for quantifying the passage of time | |
| ZA201309732B (en) | Process for the preparation of dexlansoprazole | |
| GB201101773D0 (en) | Treatment of inflammatory disorders | |
| IL228973A0 (en) | Oxymetazoline for the treatment of ano-rectal disorders | |
| GB201002842D0 (en) | Treatment of inflammatory disorders | |
| GB201106154D0 (en) | Compounds for the treatment of metabolic disorders |