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SG10201602309VA - Taxane and abeo-taxane analogs - Google Patents

Taxane and abeo-taxane analogs

Info

Publication number
SG10201602309VA
SG10201602309VA SG10201602309VA SG10201602309VA SG10201602309VA SG 10201602309V A SG10201602309V A SG 10201602309VA SG 10201602309V A SG10201602309V A SG 10201602309VA SG 10201602309V A SG10201602309V A SG 10201602309VA SG 10201602309V A SG10201602309V A SG 10201602309VA
Authority
SG
Singapore
Prior art keywords
taxane
abeo
analogs
taxane analogs
Prior art date
Application number
SG10201602309VA
Inventor
James D Mcchesney
John T Henri
Sylesh Kumar Venkataraman
Mahesh Kumar Gundluru
Original Assignee
Arbor Therapeutics Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arbor Therapeutics Llc filed Critical Arbor Therapeutics Llc
Publication of SG10201602309VA publication Critical patent/SG10201602309VA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/06Peri-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SG10201602309VA 2011-04-07 2012-04-06 Taxane and abeo-taxane analogs SG10201602309VA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161472968P 2011-04-07 2011-04-07

Publications (1)

Publication Number Publication Date
SG10201602309VA true SG10201602309VA (en) 2016-05-30

Family

ID=48781786

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2013074919A SG194128A1 (en) 2011-04-07 2012-04-06 Taxane and abeo-taxane analogs
SG10201602309VA SG10201602309VA (en) 2011-04-07 2012-04-06 Taxane and abeo-taxane analogs

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2013074919A SG194128A1 (en) 2011-04-07 2012-04-06 Taxane and abeo-taxane analogs

Country Status (10)

Country Link
US (1) US8912229B2 (en)
EP (1) EP2694055A4 (en)
JP (1) JP5970536B2 (en)
KR (1) KR20140048113A (en)
CN (1) CN103764138A (en)
AU (1) AU2012364858A1 (en)
CA (1) CA2832596A1 (en)
MX (1) MX2013011694A (en)
SG (2) SG194128A1 (en)
WO (1) WO2013106029A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX337464B (en) 2011-06-06 2016-03-07 Arbor Therapeutics Llc Acid-labile lipophilic prodrugs of cancer chemotherapeutic agents.
CN104650109B (en) * 2013-11-22 2019-01-01 江苏天士力帝益药业有限公司 Bearing taxanes
EP4000613A1 (en) 2020-11-19 2022-05-25 Polyphor Ag Pharmaceutical combinations comprising a peptide cxcr4 inhibitor and a taxane for treating cancer
EP4247407A1 (en) 2020-11-19 2023-09-27 Spexis AG Pharmaceutical combinations comprising a peptide cxcr4 inhibitor and a taxane for treating cancer
EP4223292A1 (en) 2022-02-07 2023-08-09 Cellestia Biotech AG Pharmaceutical combinations for treating cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE181551T1 (en) * 1992-04-17 1999-07-15 Abbott Lab TAXOL DERIVATIVES
CN1886400A (en) * 2003-09-25 2006-12-27 泰普斯特医药公司 9, 10-alpha, alpha-OH-taxane analogs and methods for production thereof
WO2008121476A1 (en) * 2007-03-28 2008-10-09 Tapestry Pharmaceuticals, Inc. Biologically active taxane analogs and methods of treatment by oral administration
US20080207743A1 (en) * 2007-02-28 2008-08-28 Rodger Lamb Biologically Active Taxane Analogs and Methods of Treatment
WO2008109360A1 (en) * 2007-02-28 2008-09-12 Tapestry Pharmaceuticals, Inc Taxane analogs for the treatment of brain cancer
WO2011028571A1 (en) * 2009-09-01 2011-03-10 Tapestry Pharmaceuticals, Inc. Taxane analogues, their use, pharmaceutical compositions containing them, and processes for their preparation

Also Published As

Publication number Publication date
JP5970536B2 (en) 2016-08-17
CN103764138A (en) 2014-04-30
CA2832596A1 (en) 2013-07-18
US20140093503A1 (en) 2014-04-03
WO2013106029A1 (en) 2013-07-18
JP2014512362A (en) 2014-05-22
EP2694055A1 (en) 2014-02-12
EP2694055A4 (en) 2014-09-10
SG194128A1 (en) 2013-11-29
NZ617430A (en) 2016-05-27
MX2013011694A (en) 2014-05-27
US8912229B2 (en) 2014-12-16
AU2012364858A1 (en) 2013-11-21
KR20140048113A (en) 2014-04-23

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