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SG10201501879PA - Three-dimensional structure of isoprene synthase and its use thereof for generating variants - Google Patents

Three-dimensional structure of isoprene synthase and its use thereof for generating variants

Info

Publication number
SG10201501879PA
SG10201501879PA SG10201501879PA SG10201501879PA SG10201501879PA SG 10201501879P A SG10201501879P A SG 10201501879PA SG 10201501879P A SG10201501879P A SG 10201501879PA SG 10201501879P A SG10201501879P A SG 10201501879PA SG 10201501879P A SG10201501879P A SG 10201501879PA
Authority
SG
Singapore
Prior art keywords
dimensional structure
isoprene synthase
generating variants
variants
generating
Prior art date
Application number
SG10201501879PA
Inventor
Zachary Q Beck
Richard R Bott
Christopher Lee Rife
Derek H Wells
Jeffrey V Miller
Original Assignee
Danisco Us Inc
Goodyear Tire & Rubber
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc, Goodyear Tire & Rubber filed Critical Danisco Us Inc
Publication of SG10201501879PA publication Critical patent/SG10201501879PA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/007—Preparation of hydrocarbons or halogenated hydrocarbons containing one or more isoprene units, i.e. terpenes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/03—Carbon-oxygen lyases (4.2) acting on phosphates (4.2.3)
    • C12Y402/03027—Isoprene synthase (4.2.3.27)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SG10201501879PA 2009-04-23 2010-04-22 Three-dimensional structure of isoprene synthase and its use thereof for generating variants SG10201501879PA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17219909P 2009-04-23 2009-04-23
US25583109P 2009-10-28 2009-10-28

Publications (1)

Publication Number Publication Date
SG10201501879PA true SG10201501879PA (en) 2015-05-28

Family

ID=42540820

Family Applications (1)

Application Number Title Priority Date Filing Date
SG10201501879PA SG10201501879PA (en) 2009-04-23 2010-04-22 Three-dimensional structure of isoprene synthase and its use thereof for generating variants

Country Status (7)

Country Link
US (2) US8518686B2 (en)
EP (1) EP2421966A2 (en)
CN (1) CN102656265A (en)
AU (1) AU2010238770A1 (en)
CA (1) CA2759700A1 (en)
SG (1) SG10201501879PA (en)
WO (1) WO2010124146A2 (en)

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Also Published As

Publication number Publication date
US20110076743A1 (en) 2011-03-31
AU2010238770A1 (en) 2011-11-03
US9175313B2 (en) 2015-11-03
WO2010124146A2 (en) 2010-10-28
CN102656265A (en) 2012-09-05
WO2010124146A3 (en) 2011-02-24
US20130252303A1 (en) 2013-09-26
EP2421966A2 (en) 2012-02-29
US8518686B2 (en) 2013-08-27
CA2759700A1 (en) 2010-10-28

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