SE9902741D0 - Method for the enrichment of heteroduplexes and its use in mutation detection - Google Patents
Method for the enrichment of heteroduplexes and its use in mutation detectionInfo
- Publication number
- SE9902741D0 SE9902741D0 SE9902741A SE9902741A SE9902741D0 SE 9902741 D0 SE9902741 D0 SE 9902741D0 SE 9902741 A SE9902741 A SE 9902741A SE 9902741 A SE9902741 A SE 9902741A SE 9902741 D0 SE9902741 D0 SE 9902741D0
- Authority
- SE
- Sweden
- Prior art keywords
- heteroduplexes
- nucleic acid
- protein
- selectively
- enrichment
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 238000001514 detection method Methods 0.000 title 1
- 230000035772 mutation Effects 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 abstract 3
- 102000039446 nucleic acids Human genes 0.000 abstract 3
- 150000007523 nucleic acids Chemical class 0.000 abstract 3
- 108091027305 Heteroduplex Proteins 0.000 abstract 2
- 102000018120 Recombinases Human genes 0.000 abstract 2
- 108010091086 Recombinases Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000014914 Carrier Proteins Human genes 0.000 abstract 1
- 108091008324 binding proteins Proteins 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
- C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9902741A SE9902741D0 (sv) | 1999-07-19 | 1999-07-19 | Method for the enrichment of heteroduplexes and its use in mutation detection |
| AU66948/00A AU6694800A (en) | 1999-07-18 | 2000-07-18 | A method for the enrichment of heteroduplexes and its use in mutation detection |
| PCT/EP2000/006829 WO2001005800A2 (en) | 1999-07-18 | 2000-07-18 | A method for the enrichment of heteroduplexes and its use in mutation detection |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9902741A SE9902741D0 (sv) | 1999-07-19 | 1999-07-19 | Method for the enrichment of heteroduplexes and its use in mutation detection |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE9902741D0 true SE9902741D0 (sv) | 1999-07-19 |
Family
ID=20416533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9902741A SE9902741D0 (sv) | 1999-07-18 | 1999-07-19 | Method for the enrichment of heteroduplexes and its use in mutation detection |
Country Status (3)
| Country | Link |
|---|---|
| AU (1) | AU6694800A (sv) |
| SE (1) | SE9902741D0 (sv) |
| WO (1) | WO2001005800A2 (sv) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2102365A4 (en) * | 2006-12-29 | 2010-06-09 | Applied Biosystems Llc | ENRICHMENT THROUGH HETERODUPLEX MOLECULES |
| US9279146B2 (en) * | 2012-12-21 | 2016-03-08 | Roche Molecular Systems, Inc. | Compounds and methods for the enrichment of mutated nucleic acid from a mixture |
| US9873908B2 (en) * | 2013-11-27 | 2018-01-23 | Roche Molecular Systems, Inc. | Methods for the enrichment of mutated nucleic acid from a mixture |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993020233A1 (en) * | 1992-03-27 | 1993-10-14 | University Of Maryland At Baltimore | Detection of gene mutations with mismatch repair enzymes |
| AU693198B2 (en) * | 1994-04-25 | 1998-06-25 | Avitech Diagnostics, Inc. | Detection of mutation by resolvase cleavage |
| WO1996035809A1 (en) * | 1995-05-11 | 1996-11-14 | Avitech Diagnostics Inc | Detection of mismatches by resolvase cleavage on a solid support |
| AU6886296A (en) * | 1995-09-08 | 1997-03-27 | University Of Dundee, The | Dna structure-specific nucleases |
| DE19757144A1 (de) * | 1997-12-20 | 1999-06-24 | Boerries Prof Dr Rer Na Kemper | Dualer enzymatischer Test zum Nachweis von Mutationen in DNA beliebiger Herkunft durch Endonuklease VII |
-
1999
- 1999-07-19 SE SE9902741A patent/SE9902741D0/sv unknown
-
2000
- 2000-07-18 AU AU66948/00A patent/AU6694800A/en not_active Abandoned
- 2000-07-18 WO PCT/EP2000/006829 patent/WO2001005800A2/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| AU6694800A (en) | 2001-02-05 |
| WO2001005800A3 (en) | 2001-05-10 |
| WO2001005800A2 (en) | 2001-01-25 |
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