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SE9902268D0 - Pharmaceutically active compounds - Google Patents

Pharmaceutically active compounds

Info

Publication number
SE9902268D0
SE9902268D0 SE9902268A SE9902268A SE9902268D0 SE 9902268 D0 SE9902268 D0 SE 9902268D0 SE 9902268 A SE9902268 A SE 9902268A SE 9902268 A SE9902268 A SE 9902268A SE 9902268 D0 SE9902268 D0 SE 9902268D0
Authority
SE
Sweden
Prior art keywords
active compounds
pharmaceutically active
arrhythmias
prophylaxis
useful
Prior art date
Application number
SE9902268A
Other languages
Swedish (sv)
Inventor
Gert Strandlund
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9902268A priority Critical patent/SE9902268D0/en
Publication of SE9902268D0 publication Critical patent/SE9902268D0/en
Priority to SK1827-2001A priority patent/SK18272001A3/en
Priority to KR1020017016168A priority patent/KR20020010713A/en
Priority to HK02107165.2A priority patent/HK1045520A1/en
Priority to PL00354032A priority patent/PL354032A1/en
Priority to TR2001/03663T priority patent/TR200103663T2/en
Priority to BR0011660-2A priority patent/BR0011660A/en
Priority to EEP200100675A priority patent/EE200100675A/en
Priority to NZ516013A priority patent/NZ516013A/en
Priority to PCT/SE2000/001254 priority patent/WO2000077000A1/en
Priority to CA002375841A priority patent/CA2375841A1/en
Priority to CNB008116962A priority patent/CN1144805C/en
Priority to MXPA01012919A priority patent/MXPA01012919A/en
Priority to AU60324/00A priority patent/AU761576B2/en
Priority to HU0203959A priority patent/HUP0203959A3/en
Priority to EP00946589A priority patent/EP1192157A1/en
Priority to RU2001132563/04A priority patent/RU2250903C2/en
Priority to JP2001503858A priority patent/JP2003502329A/en
Priority to IL14675400A priority patent/IL146754A0/en
Priority to CZ20014495A priority patent/CZ20014495A3/en
Priority to ARP000103015A priority patent/AR024577A1/en
Priority to ZA200109796A priority patent/ZA200109796B/en
Priority to NO20016117A priority patent/NO20016117L/en
Priority to IS6201A priority patent/IS6201A/en
Priority to US10/871,022 priority patent/US20040229900A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

There is provided compounds of formula (I), wherein R<1>, R<2>, R<3>, R<4>, R<5>, R<6>, R<7>, R<41>, R<42>, R<43>, R<44>, R<45>, R<46>, A and B have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
SE9902268A 1999-06-16 1999-06-16 Pharmaceutically active compounds SE9902268D0 (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
SE9902268A SE9902268D0 (en) 1999-06-16 1999-06-16 Pharmaceutically active compounds
CZ20014495A CZ20014495A3 (en) 1999-06-16 2000-06-15 Novel bispidine compounds suitable for treating heart arrhythmia
CA002375841A CA2375841A1 (en) 1999-06-16 2000-06-15 New bispidine compounds useful in the treatment of cardiac arrhythmias
MXPA01012919A MXPA01012919A (en) 1999-06-16 2000-06-15 New bispidine compounds useful in the treatment of cardiac arrhythmias.
HK02107165.2A HK1045520A1 (en) 1999-06-16 2000-06-15 Bispidine compounds useful in the treatment of cardiac arrhythmias
PL00354032A PL354032A1 (en) 1999-06-16 2000-06-15 New bispidine compounds useful in the treatment of cardiac arrhythmias
TR2001/03663T TR200103663T2 (en) 1999-06-16 2000-06-15 New bispidin compounds useful in the treatment of cardiac arrhythmias
BR0011660-2A BR0011660A (en) 1999-06-16 2000-06-15 Compound, pharmaceutical formulation, use of a compound, prophylaxis method or treatment of an arrhythmia and, process for the preparation of a compound
EEP200100675A EE200100675A (en) 1999-06-16 2000-06-15 Novel bispidine antiarrhythmic compounds used in the treatment of cardiac arrhythmias
NZ516013A NZ516013A (en) 1999-06-16 2000-06-15 New bispidine compounds useful in the treatment of cardiac arrhythmias
PCT/SE2000/001254 WO2000077000A1 (en) 1999-06-16 2000-06-15 New bispidine compounds useful in the treatment of cardiac arrhythmias
SK1827-2001A SK18272001A3 (en) 1999-06-16 2000-06-15 New bispidine compounds useful in the treatment of cardiac arrhythmias
CNB008116962A CN1144805C (en) 1999-06-16 2000-06-15 Bispidine compounds useful in treatment of cardiac arrhythmias
KR1020017016168A KR20020010713A (en) 1999-06-16 2000-06-15 New Bispidine Compounds Useful in the Treatment of Cardiac Arrhythmias
AU60324/00A AU761576B2 (en) 1999-06-16 2000-06-15 New bispidine compounds useful in the treatment of cardiac arrhythmias
HU0203959A HUP0203959A3 (en) 1999-06-16 2000-06-15 New bispidine compounds useful in the treatment of cardiac arrhythmias, process for their preparation and pharmaceutical compositions containing them
EP00946589A EP1192157A1 (en) 1999-06-16 2000-06-15 Bispidine compounds useful in the treatment of cardiac arrhythmias
RU2001132563/04A RU2250903C2 (en) 1999-06-16 2000-06-15 New bispidine compounds useful in treatment of cardiac arrhythmias
JP2001503858A JP2003502329A (en) 1999-06-16 2000-06-15 Novel bispidine compounds useful for the treatment of cardiac arrhythmias
IL14675400A IL146754A0 (en) 1999-06-16 2000-06-15 New bispidine compounds useful in the treatment of cardiac arrhythmias
ARP000103015A AR024577A1 (en) 1999-06-16 2000-06-16 NEW USEFUL BISPIDINE COMPOUNDS IN THE CARDIAC ARRITMIAS TREATMENT
ZA200109796A ZA200109796B (en) 1999-06-16 2001-11-28 New bispidine compounds useful in the treatment of cardiac arrhythmias.
NO20016117A NO20016117L (en) 1999-06-16 2001-12-14 New bispidine compounds useful in the treatment of cardiac arrhythmias
IS6201A IS6201A (en) 1999-06-16 2001-12-14 New bispidine compounds that are useful in the treatment of arrhythmias
US10/871,022 US20040229900A1 (en) 1999-06-16 2004-06-21 Bispidine compounds useful in the treatment of cardiac arrythmias

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9902268A SE9902268D0 (en) 1999-06-16 1999-06-16 Pharmaceutically active compounds

Publications (1)

Publication Number Publication Date
SE9902268D0 true SE9902268D0 (en) 1999-06-16

Family

ID=20416100

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9902268A SE9902268D0 (en) 1999-06-16 1999-06-16 Pharmaceutically active compounds

Country Status (24)

Country Link
EP (1) EP1192157A1 (en)
JP (1) JP2003502329A (en)
KR (1) KR20020010713A (en)
CN (1) CN1144805C (en)
AR (1) AR024577A1 (en)
AU (1) AU761576B2 (en)
BR (1) BR0011660A (en)
CA (1) CA2375841A1 (en)
CZ (1) CZ20014495A3 (en)
EE (1) EE200100675A (en)
HK (1) HK1045520A1 (en)
HU (1) HUP0203959A3 (en)
IL (1) IL146754A0 (en)
IS (1) IS6201A (en)
MX (1) MXPA01012919A (en)
NO (1) NO20016117L (en)
NZ (1) NZ516013A (en)
PL (1) PL354032A1 (en)
RU (1) RU2250903C2 (en)
SE (1) SE9902268D0 (en)
SK (1) SK18272001A3 (en)
TR (1) TR200103663T2 (en)
WO (1) WO2000077000A1 (en)
ZA (1) ZA200109796B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR030302A1 (en) * 2000-07-07 2003-08-20 Astrazeneca Ab BISPIDINE COMPOUNDS, PHARMACEUTICAL FORMULATION, USE FOR THE MANUFACTURE OF MEDICINES, PROCESS FOR THE PREPARATION OF THESE INTERMEDIATE COMPOUNDS AND COMPOUNDS
SE0101327D0 (en) 2001-04-12 2001-04-12 Astrazeneca Ab New crystalline forms
TWI499418B (en) * 2009-05-21 2015-09-11 Nerviano Medical Sciences Srl Isoquinolin-1(2h)-one derivatives
CN103702978B (en) * 2011-07-08 2018-03-06 拜耳知识产权有限责任公司 Process for preparing 2-amino-5-cyano-N, 3-dimethylbenzamide

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU1107541A1 (en) * 1982-12-03 1995-10-20 Институт Тонкой Органической Химии Им.А.Л.Мнджояна 10-nitro-1,6,8-triazatricyclo [6,3,1,1] tridecane-2,5-dione
PT88381B (en) * 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh PROCESS FOR THE PREPARATION OF NEW COMPOUNDS 3,7-DIAZABICYCLO (3,3,1) NONANO, AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS
DE3732094A1 (en) * 1987-09-24 1989-04-06 Basf Ag BISPID DERIVATIVES AS CLASS III ANTIARRHYTHMICS
US5110933A (en) * 1989-11-13 1992-05-05 Board Of Regents Of Oklahoma State University Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof
DK588489D0 (en) * 1989-11-22 1989-11-22 Ferrosan As HETEROCYCLIC COMPOUNDS, THEIR PREPARATION AND USE
TW263504B (en) * 1991-10-03 1995-11-21 Pfizer
US5468858A (en) * 1993-10-28 1995-11-21 The Board Of Regents Of Oklahoma State University Physical Sciences N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents
SE9704709D0 (en) * 1997-12-17 1997-12-17 Astra Ab Pharmaceutically active compounds

Also Published As

Publication number Publication date
BR0011660A (en) 2002-03-26
TR200103663T2 (en) 2002-05-21
MXPA01012919A (en) 2002-07-30
PL354032A1 (en) 2003-12-15
EP1192157A1 (en) 2002-04-03
WO2000077000A1 (en) 2000-12-21
ZA200109796B (en) 2003-02-28
RU2250903C2 (en) 2005-04-27
HK1045520A1 (en) 2002-11-29
JP2003502329A (en) 2003-01-21
WO2000077000A9 (en) 2003-06-19
IL146754A0 (en) 2002-07-25
AU6032400A (en) 2001-01-02
CN1370167A (en) 2002-09-18
SK18272001A3 (en) 2002-12-03
NZ516013A (en) 2003-06-30
KR20020010713A (en) 2002-02-04
NO20016117L (en) 2002-02-15
AR024577A1 (en) 2002-10-16
HUP0203959A2 (en) 2003-03-28
HUP0203959A3 (en) 2003-04-28
IS6201A (en) 2001-12-14
EE200100675A (en) 2003-02-17
CN1144805C (en) 2004-04-07
CZ20014495A3 (en) 2002-05-15
AU761576B2 (en) 2003-06-05
NO20016117D0 (en) 2001-12-14
CA2375841A1 (en) 2000-12-21

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