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SE9902056D0 - An integrin heterodimer and an alpha subunit thereof - Google Patents

An integrin heterodimer and an alpha subunit thereof

Info

Publication number
SE9902056D0
SE9902056D0 SE9902056A SE9902056A SE9902056D0 SE 9902056 D0 SE9902056 D0 SE 9902056D0 SE 9902056 A SE9902056 A SE 9902056A SE 9902056 A SE9902056 A SE 9902056A SE 9902056 D0 SE9902056 D0 SE 9902056D0
Authority
SE
Sweden
Prior art keywords
subunit
integrin
alpha subunit
integrin heterodimer
marker
Prior art date
Application number
SE9902056A
Other languages
Swedish (sv)
Inventor
Donald Gullberg
Original Assignee
Active Biotech Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20415884&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE9902056(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Active Biotech Ab filed Critical Active Biotech Ab
Priority to SE9902056A priority Critical patent/SE9902056D0/en
Publication of SE9902056D0 publication Critical patent/SE9902056D0/en
Priority to AU54355/00A priority patent/AU770652B2/en
Priority to PCT/SE2000/001135 priority patent/WO2000075187A1/en
Priority to JP2001502468A priority patent/JP2003501077A/en
Priority to AT00939232T priority patent/ATE517121T1/en
Priority to US09/980,403 priority patent/US7485429B1/en
Priority to CA002375876A priority patent/CA2375876A1/en
Priority to EP00939232A priority patent/EP1181317B1/en
Priority to JP2006119501A priority patent/JP2006246894A/en
Priority to US12/341,113 priority patent/US20090185979A1/en
Priority to US13/311,757 priority patent/US20120114708A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • C07K14/7055—Integrin beta1-subunit-containing molecules, e.g. CD29, CD49

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

A recombinant or isolated integrin heterodimer comprising a novel subunit α11 in association with a subunit β is described. The integrin or the subunit α11 can be used as marker or target of all types of cells. The integrin or subunit α11 thereof can be used as marker or target in different physiological or therapeutic methods. They can also be used as active ingredients in pharmaceutical compositions and vaccines.
SE9902056A 1999-06-03 1999-06-03 An integrin heterodimer and an alpha subunit thereof SE9902056D0 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
SE9902056A SE9902056D0 (en) 1999-06-03 1999-06-03 An integrin heterodimer and an alpha subunit thereof
EP00939232A EP1181317B1 (en) 1999-06-03 2000-05-31 An integrin heterodimer and an alpha subunit thereof
CA002375876A CA2375876A1 (en) 1999-06-03 2000-05-31 An integrin heterodimer and an alpha subunit thereof
JP2001502468A JP2003501077A (en) 1999-06-03 2000-05-31 Integrin heterodimer and its α subunit
PCT/SE2000/001135 WO2000075187A1 (en) 1999-06-03 2000-05-31 An integrin heterodimer and an alpha subunit thereof
AU54355/00A AU770652B2 (en) 1999-06-03 2000-05-31 An integrin heterodimer and an alpha subunit thereof
AT00939232T ATE517121T1 (en) 1999-06-03 2000-05-31 INTEGRIN HETERODIMER AND AN ALPHA SUBUNIT THEREOF
US09/980,403 US7485429B1 (en) 1999-06-03 2000-05-31 Integrin heterodimer and an alpha subunit thereof
JP2006119501A JP2006246894A (en) 1999-06-03 2006-04-24 INTEGRIN HETERODIMER AND alphaSUBUNIT THEREOF
US12/341,113 US20090185979A1 (en) 1999-06-03 2008-12-22 Integrin Heterodimer and an Alpha Subunit Thereof
US13/311,757 US20120114708A1 (en) 1999-06-03 2011-12-06 Integrin heterodimer and an alpha subunit thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9902056A SE9902056D0 (en) 1999-06-03 1999-06-03 An integrin heterodimer and an alpha subunit thereof

Publications (1)

Publication Number Publication Date
SE9902056D0 true SE9902056D0 (en) 1999-06-03

Family

ID=20415884

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9902056A SE9902056D0 (en) 1999-06-03 1999-06-03 An integrin heterodimer and an alpha subunit thereof

Country Status (8)

Country Link
US (3) US7485429B1 (en)
EP (1) EP1181317B1 (en)
JP (2) JP2003501077A (en)
AT (1) ATE517121T1 (en)
AU (1) AU770652B2 (en)
CA (1) CA2375876A1 (en)
SE (1) SE9902056D0 (en)
WO (1) WO2000075187A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030055231A1 (en) * 1998-10-28 2003-03-20 Jian Ni 12 human secreted proteins
US7083958B2 (en) 2000-11-20 2006-08-01 The Board Of Trustees Of The University Of Illinois Membrane scaffold proteins
US7622437B2 (en) 2000-11-20 2009-11-24 The Board Of Trustees Of The University Of Illinois Tissue factor compositions and methods
US7592008B2 (en) 2000-11-20 2009-09-22 The Board Of Trustees Of The University Of Illinois, A Body Corporate And Politic Of The State Of Illinois Membrane scaffold proteins
CA2429473C (en) 2000-11-20 2011-02-15 The Board Of Trustees Of The University Of Illinois Membrane scaffold proteins
US6858395B2 (en) 2001-02-20 2005-02-22 The Board Of Trustees Of The University Of Illinois Diagnostics assay methods and amelioration of muscular dystrophy symptoms
AU2003239016B2 (en) 2002-06-14 2007-09-20 Xintela Ab Marker for stem cells and its use
WO2008068481A1 (en) * 2006-12-05 2008-06-12 Cartela R & D Ab New compounds, methods and uses
US20110256061A1 (en) * 2006-12-18 2011-10-20 Evy Lundgren-Akerlund Binding agents to the Integrin Alpha-11 subunit, and uses thereof
WO2008075038A1 (en) * 2006-12-18 2008-06-26 Bioinvent International Ab Binding agents to the integrin alpha-11 subunit
WO2021127500A1 (en) * 2019-12-20 2021-06-24 Momenta Pharmaceuticals, Inc. Antibodies against integrin alpha 11 beta 1

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5395929A (en) * 1987-12-15 1995-03-07 Dana Farber Cancer Institute Isolated nucleic acid encoding the alpha subunit of the human leukocyte adhesion receptor
AU638964B2 (en) * 1988-12-22 1993-07-15 Genentech Inc. Method for preparing water soluble polypeptides
US5310874A (en) * 1991-05-03 1994-05-10 The Scripps Research Institute Integrin α subunit cytoplasmic domain polypeptides and antibodies
US5304603A (en) * 1991-06-18 1994-04-19 The Population Council Leydig cell stimulator
GB9122820D0 (en) * 1991-10-28 1991-12-11 Wellcome Found Stabilised antibodies
EP0635029A4 (en) * 1992-04-10 1996-01-24 Gen Hospital Corp Cartilage matrix protein and methods for use.
US5840299A (en) 1994-01-25 1998-11-24 Athena Neurosciences, Inc. Humanized antibodies against leukocyte adhesion molecule VLA-4
US5968770A (en) * 1995-02-10 1999-10-19 Millennium Pharmaceuticals, Inc. Compositions and methods for the treatment and diagnosis of cardiovascular disease using rchd523 as a target
JP2001506595A (en) * 1996-11-21 2001-05-22 シーオーアール セラピューティクス，インコーポレイテッド Regulation of the interaction between myosin and integrins
US7368531B2 (en) 1997-03-07 2008-05-06 Human Genome Sciences, Inc. Human secreted proteins
US20060122373A1 (en) 1997-04-04 2006-06-08 Millennium Pharmaceuticals, Inc. Delta3, FTHMA-070, Tango85, Tango77, SPOIL,NEOKINE, Tango129 and integrin alpha subunit protein and nucleic acid molecules and uses thereof
US6046316A (en) * 1997-12-09 2000-04-04 Wayne State University Nucleic acid encoding truncated integrins
JP4912528B2 (en) * 1998-04-02 2012-04-11 キシンテラ、アクチボラグ Integrin heterodimer and its subunits
CA2348824A1 (en) * 1998-10-28 2000-05-25 Human Genome Sciences, Inc. 12 human secreted proteins
US20030129685A1 (en) 1998-10-28 2003-07-10 Jian Ni 12 human secreted proteins
US20030055231A1 (en) 1998-10-28 2003-03-20 Jian Ni 12 human secreted proteins
WO2000073339A1 (en) 1999-05-28 2000-12-07 Millennium Pharmaceuticals, Inc. NOVEL INTEGRIN αSUBUNIT AND USES THEREOF
JP2005530856A (en) 2002-06-21 2005-10-13 ジョンズ ホプキンス ユニバーシティー スクール オブ メディシン Membrane-related tumor endothelial marker
US7294290B2 (en) * 2003-08-01 2007-11-13 Ngx, Inc. Photochromic composition in a solid matrix

Also Published As

Publication number Publication date
US20120114708A1 (en) 2012-05-10
CA2375876A1 (en) 2000-12-14
EP1181317B1 (en) 2011-07-20
AU5435500A (en) 2000-12-28
JP2003501077A (en) 2003-01-14
AU770652B2 (en) 2004-02-26
US7485429B1 (en) 2009-02-03
EP1181317A1 (en) 2002-02-27
US20090185979A1 (en) 2009-07-23
ATE517121T1 (en) 2011-08-15
WO2000075187A1 (en) 2000-12-14
JP2006246894A (en) 2006-09-21

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