SE9804248D0 - Anti-coagulation with calcium containing citrate solution - Google Patents
Anti-coagulation with calcium containing citrate solutionInfo
- Publication number
- SE9804248D0 SE9804248D0 SE9804248A SE9804248A SE9804248D0 SE 9804248 D0 SE9804248 D0 SE 9804248D0 SE 9804248 A SE9804248 A SE 9804248A SE 9804248 A SE9804248 A SE 9804248A SE 9804248 D0 SE9804248 D0 SE 9804248D0
- Authority
- SE
- Sweden
- Prior art keywords
- product
- blood
- coagulated
- coagulant
- blood product
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
A method of anti-coagulating a blood product and counteracting the reduction of calcium ion activity in the anti-coagulated product, is disclosed. The method comprises addition to the blood product of an anti-coagulant selected from the group consisting of soluble citrate compounds, citric acid, and mixtures thereof in an amount of 13-60 mmole citrate per liter of anti-coagulated blood product, and of a soluble calcium compound in an amount giving a calcium ion activity in the anti-coagulated blood product of 0.2 - 10mM. Further, an anti-coagulated blood or blood plasma product comprising such an anti-coagulant and calcium compound, and its use for the production of coagulation Factor VIII, are described. Additionally, a blood sampling container comprising an aqueous solution of such an anti-coagulant and calcium compound, and its use for transport and storage of the anti-coagulated blood product, are disclosed.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9804248A SE9804248D0 (en) | 1998-12-07 | 1998-12-07 | Anti-coagulation with calcium containing citrate solution |
AU20174/00A AU2017400A (en) | 1998-12-07 | 1999-12-06 | Anti-coagulation with calcium containing citrate solution |
PCT/SE1999/002271 WO2000033853A1 (en) | 1998-12-07 | 1999-12-06 | Anti-coagulation with calcium containing citrate solution |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9804248A SE9804248D0 (en) | 1998-12-07 | 1998-12-07 | Anti-coagulation with calcium containing citrate solution |
Publications (1)
Publication Number | Publication Date |
---|---|
SE9804248D0 true SE9804248D0 (en) | 1998-12-07 |
Family
ID=20413589
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9804248A SE9804248D0 (en) | 1998-12-07 | 1998-12-07 | Anti-coagulation with calcium containing citrate solution |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2017400A (en) |
SE (1) | SE9804248D0 (en) |
WO (1) | WO2000033853A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8105258B2 (en) | 1999-04-26 | 2012-01-31 | Baxter International Inc. | Citrate anticoagulation system for extracorporeal blood treatments |
US7186420B2 (en) | 1999-04-26 | 2007-03-06 | Edwards Lifesciences Corporation | Multi-part substitution infusion fluids and matching anticoagulants |
EP1176969B1 (en) | 1999-04-26 | 2008-08-20 | Edwards Lifesciences AG | Substitution infusion fluid and citrate anticoagulation |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3615558A1 (en) * | 1986-05-09 | 1987-11-12 | Behringwerke Ag | METHOD FOR PRODUCING A FACTOR V CONCENTRATE |
GB8708181D0 (en) * | 1987-04-06 | 1987-05-13 | Wensley R | Extraction of protein from blood |
-
1998
- 1998-12-07 SE SE9804248A patent/SE9804248D0/en unknown
-
1999
- 1999-12-06 AU AU20174/00A patent/AU2017400A/en not_active Abandoned
- 1999-12-06 WO PCT/SE1999/002271 patent/WO2000033853A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2000033853A1 (en) | 2000-06-15 |
AU2017400A (en) | 2000-06-26 |
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