SE9802788D0 - Immunogenic region recognized by circulating autoantibodies from goodpasture patients - Google Patents
Immunogenic region recognized by circulating autoantibodies from goodpasture patientsInfo
- Publication number
- SE9802788D0 SE9802788D0 SE9802788A SE9802788A SE9802788D0 SE 9802788 D0 SE9802788 D0 SE 9802788D0 SE 9802788 A SE9802788 A SE 9802788A SE 9802788 A SE9802788 A SE 9802788A SE 9802788 D0 SE9802788 D0 SE 9802788D0
- Authority
- SE
- Sweden
- Prior art keywords
- circulating autoantibodies
- immunogenic region
- autoantibodies
- goodpasture
- patients
- Prior art date
Links
- 230000002163 immunogen Effects 0.000 title abstract 2
- 102000004266 Collagen Type IV Human genes 0.000 abstract 1
- 108010042086 Collagen Type IV Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Rehabilitation Therapy (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention refers to an immunogenic region comprising a part of the non-collagenous domain of the alpha 3 chain of type IV collagen having intact cysteine residues, said part being recognized by circulating autoantibodies from Goodpasture patients. This part comprises at least five amino acid residues which are substantially non-adjacent in the amino acid sequence, it is located in the amino terminal end of said alpha 3 chain, and it is exposed to said autoantibodies. The invention also refers to methods for the determination in body fluids of circulating autoantibodies from Goodpasture patients.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9802788A SE9802788D0 (en) | 1998-08-21 | 1998-08-21 | Immunogenic region recognized by circulating autoantibodies from goodpasture patients |
| PCT/SE1999/001416 WO2000011475A1 (en) | 1998-08-21 | 1999-08-20 | Immunogenic region recognized by circulating autoantibodies from goodpasture patients |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9802788A SE9802788D0 (en) | 1998-08-21 | 1998-08-21 | Immunogenic region recognized by circulating autoantibodies from goodpasture patients |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE9802788D0 true SE9802788D0 (en) | 1998-08-21 |
Family
ID=20412303
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9802788A SE9802788D0 (en) | 1998-08-21 | 1998-08-21 | Immunogenic region recognized by circulating autoantibodies from goodpasture patients |
Country Status (2)
| Country | Link |
|---|---|
| SE (1) | SE9802788D0 (en) |
| WO (1) | WO2000011475A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6759047B1 (en) | 1998-06-17 | 2004-07-06 | Beth Israel Deaconess Hospital Corp. | Anti-angiogenic proteins and methods of use thereof |
| US6962974B1 (en) | 1998-06-17 | 2005-11-08 | Beth Israel Deaconess Medical Center | Anti-angiogenic proteins and fragments and methods of use thereof |
| US7387779B2 (en) | 1998-06-17 | 2008-06-17 | Beth Israel Deaconess Medical Center | Anti-angiogenic proteins and fragments and methods of use thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5424408A (en) * | 1990-11-30 | 1995-06-13 | Yale University | α-3 chain type IV collagen polynucleotides |
-
1998
- 1998-08-21 SE SE9802788A patent/SE9802788D0/en unknown
-
1999
- 1999-08-20 WO PCT/SE1999/001416 patent/WO2000011475A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000011475A1 (en) | 2000-03-02 |
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