SE9003476L - Novel isoindole derivatives and salts thereof, process for producing the same and antitumor agent comprising the same - Google Patents

Novel isoindole derivatives and salts thereof, process for producing the same and antitumor agent comprising the same

Info

Publication number: SE9003476L
Authority: SE; Sweden
Prior art keywords: same; salts; producing; antitumor agent; isoindole derivatives
Prior art date: 1989-11-01

Application number

SE9003476A

Other languages

English (en)

Other versions

SE509700C2 (sv

SE9003476D0 (sv

Inventor

T Nagai

Original Assignee

Toyama Chemical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-01

Filing date

1990-10-31

Publication date

1992-05-01

1990-10-25 Priority claimed from JP2-288069A external-priority patent/JP3027599B2/ja

1990-10-31 Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd

1990-10-31 Publication of SE9003476D0 publication Critical patent/SE9003476D0/sv

1992-05-01 Publication of SE9003476L publication Critical patent/SE9003476L/sv

1999-02-22 Publication of SE509700C2 publication Critical patent/SE509700C2/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

SE9003476A 1989-11-01 1990-10-31 Nya isoindolderivat och salter därav, förfaranden för framställning därav samt anti-tumörmedel som innehåller dem SE509700C2 (sv)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP28554889		1989-11-01
JP20544390		1990-08-02
JP2-288069A JP3027599B2 (ja)	1990-08-02	1990-10-25	新規なイソインドール誘導体およびその塩

Publications (3)

Publication Number	Publication Date
SE9003476D0 SE9003476D0 (sv)	1990-10-31
SE9003476L true SE9003476L (sv)	1992-05-01
SE509700C2 SE509700C2 (sv)	1999-02-22

Family

ID=27328497

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE9003476A SE509700C2 (sv)	1989-11-01	1990-10-31	Nya isoindolderivat och salter därav, förfaranden för framställning därav samt anti-tumörmedel som innehåller dem

Country Status (11)

Country	Link
US (1)	US5166204A (sv)
BE (1)	BE1004069A3 (sv)
CA (1)	CA2028960C (sv)
CH (1)	CH682151A5 (sv)
DE (1)	DE4034687C2 (sv)
DK (1)	DK261890A (sv)
FR (1)	FR2655345B1 (sv)
GB (1)	GB2239013B (sv)
IT (1)	IT1242004B (sv)
NL (1)	NL9002366A (sv)
SE (1)	SE509700C2 (sv)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9215361D0 (en) *	1992-07-20	1992-09-02	Wellcome Found	Heterocyclic compounds
ES2123873T3 (es) *	1994-08-04	1999-01-16	Hoffmann La Roche	Pirrolocarbazol.
WO1996028447A1 (fr) *	1995-03-09	1996-09-19	Kyowa Hakko Kogyo Co., Ltd.	Derives de pyrrolocarbazole
FR2751655B1 (fr) *	1996-07-26	1998-08-28	Adir	Nouveaux derives de bis-imides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE19744257B4 (de) *	1997-10-07	2004-04-15	Zentaris Gmbh	Beta-Carboline und deren Verwendung zur Behandlung von malignen und anderen, auf pathologischen Zellproliferationen beruhenden Erkrankungen
US20060276497A1 (en) *	2000-05-09	2006-12-07	Cephalon, Inc.	Novel multicyclic compounds and the use thereof
US7122679B2 (en) *	2000-05-09	2006-10-17	Cephalon, Inc.	Multicyclic compounds and the use thereof
AU2002354499A1 (en) *	2001-12-18	2003-06-30	Kyowa Hakko Kogyo Co., Ltd.	Indole derivative
BR0309783A (pt) *	2002-04-26	2005-03-22	Warner Lambert Co	Inibidores de quinases de pontos de controlo (wee1 e chk1)
CN100400529C (zh) *	2003-10-08	2008-07-09	中国科学院化学研究所	含氟芳香族有机四酸二酐及制备方法和用途
US8076353B2 (en) *	2004-03-15	2011-12-13	Ptc Therapeutics, Inc.	Inhibition of VEGF translation
US7767689B2 (en) *	2004-03-15	2010-08-03	Ptc Therapeutics, Inc.	Carboline derivatives useful in the treatment of cancer
US8076352B2 (en) *	2004-03-15	2011-12-13	Ptc Therapeutics, Inc.	Administration of carboline derivatives useful in the treatment of cancer and other diseases
MXPA06010542A (es) *	2004-03-15	2007-03-28	Ptc Therapeutics Inc	Derivados de carbolina tetra-ciclica para la inhibicion de angiogenesis.
UA92317C2 (ru) *	2004-03-15	2010-10-25	Пи-Ти-Си ТЕРАПЬЮТИКС, ИНК.	Производные карболина, пригодные для ингибирования развития кровеносных сосудов
JP2008520740A (ja) *	2004-11-23	2008-06-19	ピーティーシーセラピューティクス，インコーポレイテッド	Ｖｅｇｆ産生を阻害する活性因子としての置換されたフェノール
CN101103000B (zh) *	2004-11-23	2012-06-27	Ptc医疗公司	用于抑制vegf生成的咔唑、咔啉和吲哚衍生物
CN110464722B (zh) *	2019-06-06	2023-05-23	暨南大学	一类小分子化合物或其药学上可接受的盐在制备抗肿瘤转移药物中的应用
CN115594681B (zh) *	2022-10-21	2024-06-18	广州六顺生物科技有限公司	一种异吲哚啉-1,3-二酮衍生物及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1988007045A1 (en) *	1987-03-09	1988-09-22	Kyowa Hakko Kogyo Co., Ltd.	Derivatives of physiologically active substance k-252
DE3833008A1 (de) *	1988-09-29	1990-04-05	Goedecke Ag	Pyrrolocarbozol-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel

1990
- 1990-10-30 US US07/605,430 patent/US5166204A/en not_active Expired - Fee Related
- 1990-10-30 GB GB9023568A patent/GB2239013B/en not_active Expired - Fee Related
- 1990-10-31 CH CH3464/90A patent/CH682151A5/de not_active IP Right Cessation
- 1990-10-31 SE SE9003476A patent/SE509700C2/sv not_active IP Right Cessation
- 1990-10-31 DE DE4034687A patent/DE4034687C2/de not_active Expired - Fee Related
- 1990-10-31 DK DK261890A patent/DK261890A/da not_active Application Discontinuation
- 1990-10-31 CA CA002028960A patent/CA2028960C/en not_active Expired - Fee Related
- 1990-10-31 NL NL9002366A patent/NL9002366A/nl not_active Application Discontinuation
- 1990-10-31 BE BE9001032A patent/BE1004069A3/fr not_active IP Right Cessation
- 1990-10-31 IT IT48430A patent/IT1242004B/it active IP Right Grant
- 1990-10-31 FR FR9013552A patent/FR2655345B1/fr not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IT1242004B (it)	1994-02-02
FR2655345A1 (sv)	1991-06-07
GB2239013A (en)	1991-06-19
IT9048430A0 (it)	1990-10-31
BE1004069A3 (fr)	1992-09-15
DK261890A (da)	1991-05-02
US5166204A (en)	1992-11-24
FR2655345B1 (sv)	1993-02-26
GB9023568D0 (en)	1990-12-12
SE509700C2 (sv)	1999-02-22
GB2239013B (en)	1993-06-02
DE4034687A1 (de)	1991-05-02
CH682151A5 (sv)	1993-07-30
CA2028960A1 (en)	1991-05-02
DK261890D0 (da)	1990-10-31
CA2028960C (en)	1999-01-19
IT9048430A1 (it)	1992-05-01
SE9003476D0 (sv)	1990-10-31
DE4034687C2 (de)	1999-12-02
NL9002366A (nl)	1991-06-03

Publication	Publication Date	Title
SE9003476L (sv)	1992-05-01	Novel isoindole derivatives and salts thereof, process for producing the same and antitumor agent comprising the same
GB2210879B (en)	1991-09-18	4h-1-benzopyran-4-one derivative or its salt, process for producing the same and pharmaceutical composition comprising the same as active ingredient
GR3033397T3 (en)	2000-09-29	Novel tetrapeptide derivative.
PL292095A1 (en)	1992-11-02	Pesticides and method of obtaining them
ZA916268B (en)	1992-04-29	Tricyclic compound or salts thereof,method for producing the same and antimicrobial agent containing the same
NO920614L (no)	1992-03-24	Forbindelse med antitumorvirkning og fremstilling derav
ATE158793T1 (de)	1997-10-15	Neue salzform von 5-difluormethoxy-2- (3,4- dimethoxy-2-pyridyl)methylsulfinyl>-1h- benzimidazol
NO951135L (no)	1995-05-08	Syntese av N-acetyl-neuraminsyrederivater
AU575342B2 (en)	1988-07-28	Gamma - butyrolactone derivatives
DK0662967T3 (da)	1998-09-14	Syntese af N-acetyl-neuraminsyrederivater
ES456359A1 (es)	1978-02-01	Procedimiento para preparar derivados de n-trocloroacetil- n'-clorobenzoilhidrazina.
ATE200291T1 (de)	2001-04-15	Cephemderivate
ATE90685T1 (de)	1993-07-15	Disaccharidderivate.
FI902901A0 (fi)	1990-06-11	Dibenzol/1,5/dioxocin-5-one-derivat, deras anvaendning i laekemedel och foerfarande foer deras framstaellning.
DE69122555D1 (de)	1996-11-14	2,4-Dihydroxyadipinsäurederivate
NO941084L (no)	1994-03-24	Neuroleptiske 2-substituerte perhydro-1-H-pyrido[1,2-aÅpyraziner
ATE237619T1 (de)	2003-05-15	Sesquiterpen-derivate mit antiviraler aktivität
RU93051079A (ru)	1996-09-20	Фармацевтические соединения, способ получения, фармацевтическая композиция
ES2052812T3 (es)	1994-07-16	Un procedimiento para la preparacion de derivados de pirrolizina.
EP0369749A3 (en)	1991-08-07	Anti-tumor compounds
FR2661911B1 (fr)	1992-07-31	Procede de preparation de derives de la thieno-triazolo-diazepine.
FR2664588B1 (fr)	1993-08-20	Procede de synthese de derives fluores.
ES2019841A6 (es)	1991-07-01	Procedimiento para preparar derivados de tieno-triazolo-diazepina.

Legal Events

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