SE8902699D0 - DILTIAZEM CONTAINING PHARMACEUTICAL COMPOSITIOS - Google Patents
DILTIAZEM CONTAINING PHARMACEUTICAL COMPOSITIOSInfo
- Publication number
- SE8902699D0 SE8902699D0 SE8902699A SE8902699A SE8902699D0 SE 8902699 D0 SE8902699 D0 SE 8902699D0 SE 8902699 A SE8902699 A SE 8902699A SE 8902699 A SE8902699 A SE 8902699A SE 8902699 D0 SE8902699 D0 SE 8902699D0
- Authority
- SE
- Sweden
- Prior art keywords
- unit
- diltiazem
- compositios
- administered
- partly
- Prior art date
Links
- HSUGRBWQSSZJOP-RTWAWAEBSA-N diltiazem Chemical compound C1=CC(OC)=CC=C1[C@H]1[C@@H](OC(C)=O)C(=O)N(CCN(C)C)C2=CC=CC=C2S1 HSUGRBWQSSZJOP-RTWAWAEBSA-N 0.000 title abstract 3
- 229960004166 diltiazem Drugs 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 abstract 4
- 239000008187 granular material Substances 0.000 abstract 3
- 239000001856 Ethyl cellulose Substances 0.000 abstract 2
- ZZSNKZQZMQGXPY-UHFFFAOYSA-N Ethyl cellulose Chemical compound CCOCC1OC(OC)C(OCC)C(OCC)C1OC1C(O)C(O)C(OC)C(CO)O1 ZZSNKZQZMQGXPY-UHFFFAOYSA-N 0.000 abstract 2
- 229920006318 anionic polymer Polymers 0.000 abstract 2
- 229920001249 ethyl cellulose Polymers 0.000 abstract 2
- 235000019325 ethyl cellulose Nutrition 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000011248 coating agent Substances 0.000 abstract 1
- 238000000576 coating method Methods 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention relates to a pharmaceutical composition containing diltiazem as a therapeutically active ingredient and to be administered in the form of a multiple-unit-dose granule formulation once and/or twice a day, wherein a diltiazem acid addition salt is administered partly in the form of an uncoated multiple-unit-dose granule, and partly in the form of a multiple-unit-dose granule being coated with a mixture of ethyl cellulose and an anionic polymer which dissolves at a pH of above 5.0 and whereby said composition releases and whereby the coating mixture contains 20-40 parts per weight of anionic polymer in relation to 80-60 parts per weight of ethyl cellulose.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8902699A SE8902699D0 (en) | 1989-08-09 | 1989-08-09 | DILTIAZEM CONTAINING PHARMACEUTICAL COMPOSITIOS |
| PCT/SE1990/000500 WO1991001722A1 (en) | 1989-08-09 | 1990-07-23 | Diltiazem containing pharmaceutical compositions |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8902699A SE8902699D0 (en) | 1989-08-09 | 1989-08-09 | DILTIAZEM CONTAINING PHARMACEUTICAL COMPOSITIOS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE8902699D0 true SE8902699D0 (en) | 1989-08-09 |
Family
ID=20376653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8902699A SE8902699D0 (en) | 1989-08-09 | 1989-08-09 | DILTIAZEM CONTAINING PHARMACEUTICAL COMPOSITIOS |
Country Status (2)
| Country | Link |
|---|---|
| SE (1) | SE8902699D0 (en) |
| WO (1) | WO1991001722A1 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA923474B (en) * | 1991-05-20 | 1993-01-27 | Marion Merrell Dow Inc | Diltiazem formulation |
| US5286497A (en) * | 1991-05-20 | 1994-02-15 | Carderm Capital L.P. | Diltiazem formulation |
| KR100221695B1 (en) * | 1991-08-12 | 1999-09-15 | 그린 마틴, 브라이언 쥐 테슬리 | Pharmaceutical Formulation Formulations |
| SE9301057L (en) * | 1993-03-30 | 1994-10-01 | Pharmacia Ab | Controlled release preparation |
| US5834024A (en) | 1995-01-05 | 1998-11-10 | Fh Faulding & Co. Limited | Controlled absorption diltiazem pharmaceutical formulation |
| US7108866B1 (en) | 1999-12-10 | 2006-09-19 | Biovall Laboratories International Srl | Chronotherapeutic diltiazem formulations and the administration thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4173626A (en) * | 1978-12-11 | 1979-11-06 | Merck & Co., Inc. | Sustained release indomethacin |
| JPS5846019A (en) * | 1981-09-14 | 1983-03-17 | Kanebo Ltd | Nifedipine preparation with prolonged action |
| DK173505B1 (en) * | 1987-02-20 | 2001-01-15 | Pharmatec Internat S R L | Process for producing a slow release diltiazem pellet and using pellets thus prepared |
| FR2623714B1 (en) * | 1987-11-26 | 1990-04-20 | Ethypharm Sa | EXTENDED RELEASE FORM OF DILTIAZEM AND ITS MEDICINAL PRODUCT |
-
1989
- 1989-08-09 SE SE8902699A patent/SE8902699D0/en unknown
-
1990
- 1990-07-23 WO PCT/SE1990/000500 patent/WO1991001722A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| WO1991001722A1 (en) | 1991-02-21 |
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