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SE8800480L - ARYLAMIDES OF ALFA-HEXAMETHYLENIMINOCARBONIC ACIDS AND HYDROCHLORIDES OF THESE ARYLAMIDES - Google Patents

ARYLAMIDES OF ALFA-HEXAMETHYLENIMINOCARBONIC ACIDS AND HYDROCHLORIDES OF THESE ARYLAMIDES

Info

Publication number
SE8800480L
SE8800480L SE8800480A SE8800480A SE8800480L SE 8800480 L SE8800480 L SE 8800480L SE 8800480 A SE8800480 A SE 8800480A SE 8800480 A SE8800480 A SE 8800480A SE 8800480 L SE8800480 L SE 8800480L
Authority
SE
Sweden
Prior art keywords
arylamides
hydrochlorides
acids
hexamethyleniminocarbonic
alfa
Prior art date
Application number
SE8800480A
Other languages
Swedish (sv)
Other versions
SE8800480D0 (en
Inventor
A S Lebedeva
A V Stavrovskaya
I V Chernyakova
A M Likhosherstov
A P Rodionov
N M Sipilina
T I Ivanova
V A Zagorevsky
A P Skoldinov
V N Zhukov
B M Pyatin
B I Ljubimov
Original Assignee
Nii Farmakol Akad Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from SU874194710A external-priority patent/SU1528773A1/en
Application filed by Nii Farmakol Akad Med filed Critical Nii Farmakol Akad Med
Publication of SE8800480D0 publication Critical patent/SE8800480D0/en
Publication of SE8800480L publication Critical patent/SE8800480L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Anesthesiology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)

Abstract

The present invention relates to novel chemical compounds, to be precise arylamides of alpha -hexamethyleneiminocarboxylic acids and their hydrochlorides of the following general formula: <IMAGE> in which R is H, CH3, C2H5, n-C3H7; R' is H or CH3; and X is absent or is HCl. The compounds according to the invention have a prolonged local anaesthetic action and can be used in medicine.
SE8800480A 1987-02-13 1988-02-12 ARYLAMIDES OF ALFA-HEXAMETHYLENIMINOCARBONIC ACIDS AND HYDROCHLORIDES OF THESE ARYLAMIDES SE8800480L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SU4194711 1987-02-13
SU874194710A SU1528773A1 (en) 1987-02-13 1987-02-13 Chlorohydrates of arylamines of alpha-hexamethylene iminocarbolic acids possessing local anaesthesizing activity

Publications (2)

Publication Number Publication Date
SE8800480D0 SE8800480D0 (en) 1988-02-12
SE8800480L true SE8800480L (en) 1988-08-14

Family

ID=26666095

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8800480A SE8800480L (en) 1987-02-13 1988-02-12 ARYLAMIDES OF ALFA-HEXAMETHYLENIMINOCARBONIC ACIDS AND HYDROCHLORIDES OF THESE ARYLAMIDES

Country Status (6)

Country Link
JP (1) JPS63264472A (en)
DE (1) DE3804433A1 (en)
DK (1) DK68488A (en)
FI (1) FI880581L (en)
NO (1) NO880604L (en)
SE (1) SE8800480L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8900685D0 (en) * 1989-02-28 1989-02-28 Astra Ab NEW COMPOUNDS

Also Published As

Publication number Publication date
FI880581A0 (en) 1988-02-09
DK68488A (en) 1988-08-14
JPS63264472A (en) 1988-11-01
SE8800480D0 (en) 1988-02-12
DE3804433A1 (en) 1988-08-25
NO880604L (en) 1988-08-15
NO880604D0 (en) 1988-02-11
FI880581L (en) 1988-08-14
DK68488D0 (en) 1988-02-10

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Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 8800480-9

Effective date: 19910901