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SE8705187L - NEW AMINOALKANOYL-DIBENSO / D, G // 1,3,6 / DIOXAZOCINES AND A PROCEDURE FOR PREPARING THEREOF - Google Patents

NEW AMINOALKANOYL-DIBENSO / D, G // 1,3,6 / DIOXAZOCINES AND A PROCEDURE FOR PREPARING THEREOF

Info

Publication number
SE8705187L
SE8705187L SE8705187A SE8705187A SE8705187L SE 8705187 L SE8705187 L SE 8705187L SE 8705187 A SE8705187 A SE 8705187A SE 8705187 A SE8705187 A SE 8705187A SE 8705187 L SE8705187 L SE 8705187L
Authority
SE
Sweden
Prior art keywords
dioxazocines
aminoalkanoyl
dibenso
preparing
procedure
Prior art date
Application number
SE8705187A
Other languages
Swedish (sv)
Other versions
SE8705187D0 (en
SE465429B (en
Inventor
L Rozsa
L Petocz
M Fekete
E Szirt
M Hegedus
I Gacsalyi
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of SE8705187D0 publication Critical patent/SE8705187D0/en
Publication of SE8705187L publication Critical patent/SE8705187L/en
Publication of SE465429B publication Critical patent/SE465429B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • C07D273/01—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00 having one nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D273/00—Heterocyclic compounds containing rings having nitrogen and oxygen atoms as the only ring hetero atoms, not provided for by groups C07D261/00 - C07D271/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Aminoalkanoyl-dibenzo-[d,g] [1,3,6] dioxazocines of the formula <IMAGE> wherein X is hydrogen or halo; A is a valence bond or a C1-10 straight or branched chained alkylene; R1 and R2 are independently hydrogen, C1-4alkyl or C3-6cycloalkyl; or R1 and R2 together with the nitrogen they are attached to and optionally with one or more further nitrogen, oxygen and/or sulfur atoms (s) form a 5- to 6- membered heterocyclic group optionally substituted with C1-4 alkyl and pharmaceutically acceptable acid addition salts thereof, have local anaesthetic, tranquillo-sedative, antiparkinsonic antiarhythmic and antianginous activity.
SE8705187A 1986-12-30 1987-12-29 NEW AMINOALCANOYL-DIBENSO / D, G / / 1,3,6 / DIOXAZOCINES, PROCEDURES FOR PREPARING THEREOF AND PHARMACEUTICAL PREPARATION SE465429B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU865513A HU198194B (en) 1986-12-30 1986-12-30 Process for production of new derivatives of dioxazocin and medical compositions containing them

Publications (3)

Publication Number Publication Date
SE8705187D0 SE8705187D0 (en) 1987-12-29
SE8705187L true SE8705187L (en) 1988-07-01
SE465429B SE465429B (en) 1991-09-09

Family

ID=10970381

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8705187A SE465429B (en) 1986-12-30 1987-12-29 NEW AMINOALCANOYL-DIBENSO / D, G / / 1,3,6 / DIOXAZOCINES, PROCEDURES FOR PREPARING THEREOF AND PHARMACEUTICAL PREPARATION

Country Status (26)

Country Link
JP (1) JPS63174978A (en)
KR (1) KR880007502A (en)
CN (1) CN87108190A (en)
AT (1) AT389304B (en)
AU (1) AU596258B2 (en)
BE (1) BE1001240A3 (en)
CH (1) CH675877A5 (en)
CS (1) CS270579B2 (en)
DD (1) DD267038A5 (en)
DE (1) DE3744549A1 (en)
DK (1) DK691087A (en)
ES (1) ES2006539A6 (en)
FI (1) FI875767A (en)
FR (1) FR2609030B1 (en)
GB (1) GB2199827B (en)
GR (1) GR872083B (en)
HU (1) HU198194B (en)
IL (1) IL84976A (en)
IT (1) IT1233443B (en)
NL (1) NL8703150A (en)
NO (1) NO169230B (en)
PL (1) PL151402B1 (en)
SE (1) SE465429B (en)
SU (1) SU1575938A3 (en)
YU (1) YU235287A (en)
ZA (1) ZA879733B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU201318B (en) * 1987-12-31 1990-10-28 Egyt Gyogyszervegyeszeti Gyar Process for producing dioxazoline derivatives and pharmaceutical compositions comprising same
ES2058761T3 (en) * 1989-10-20 1994-11-01 Akzo Nv PROCESS FOR THE PREPARATION OF DIBENZODIOXAZECINE AND DIBENZODIOXAAZACICLOUNDECINE DERIVATIVES.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2659M (en) * 1963-04-25 1964-08-14 Millot Lab Drug based on a phenothiazine derivative.
HU174126B (en) * 1977-08-02 1979-11-28 Egyt Gyogyszervegyeszeti Gyar Process for producing new dibenzo-square bracket-d,g-square bracket closed-square bracket-1,3,6-square bracket closed--dioxazocine-derivatives
HU195491B (en) * 1985-12-20 1988-05-30 Egyt Gyogyszervegyeszeti Gyar Process for production of optically active 2-chlor-12-/3-/dimethil-amin/-2-methil-prophil/-12h-dibenzol /d,g/ /1,3,6/-diaxazocine and medical compositions containing such compounds
HU201318B (en) * 1987-12-31 1990-10-28 Egyt Gyogyszervegyeszeti Gyar Process for producing dioxazoline derivatives and pharmaceutical compositions comprising same

Also Published As

Publication number Publication date
CN87108190A (en) 1988-07-13
IL84976A (en) 1991-09-16
GB2199827A (en) 1988-07-20
NO875465D0 (en) 1987-12-29
YU235287A (en) 1988-10-31
ES2006539A6 (en) 1989-05-01
FI875767A (en) 1988-07-01
DE3744549A1 (en) 1988-07-14
DK691087A (en) 1988-07-01
FI875767A0 (en) 1987-12-30
NO169230B (en) 1992-02-17
PL269812A1 (en) 1988-09-15
AT389304B (en) 1989-11-27
GB8730298D0 (en) 1988-02-03
IL84976A0 (en) 1988-06-30
AU8314087A (en) 1988-06-30
FR2609030B1 (en) 1991-05-31
JPS63174978A (en) 1988-07-19
IT1233443B (en) 1992-04-01
CS1009187A2 (en) 1989-11-14
DD267038A5 (en) 1989-04-19
CS270579B2 (en) 1990-07-12
HU198194B (en) 1989-08-28
FR2609030A1 (en) 1988-07-01
HUT47260A (en) 1989-02-28
NL8703150A (en) 1988-07-18
BE1001240A3 (en) 1989-08-29
GB2199827B (en) 1990-10-03
GR872083B (en) 1988-04-27
ZA879733B (en) 1988-06-24
NO875465L (en) 1988-07-01
SE8705187D0 (en) 1987-12-29
SE465429B (en) 1991-09-09
KR880007502A (en) 1988-08-27
AU596258B2 (en) 1990-04-26
IT8723271A0 (en) 1987-12-30
DK691087D0 (en) 1987-12-29
CH675877A5 (en) 1990-11-15
ATA345087A (en) 1989-04-15
PL151402B1 (en) 1990-08-31
SU1575938A3 (en) 1990-06-30

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