[go: up one dir, main page]

SE8702550D0 - Cysteinproteashemmare - Google Patents

Cysteinproteashemmare

Info

Publication number
SE8702550D0
SE8702550D0 SE8702550A SE8702550A SE8702550D0 SE 8702550 D0 SE8702550 D0 SE 8702550D0 SE 8702550 A SE8702550 A SE 8702550A SE 8702550 A SE8702550 A SE 8702550A SE 8702550 D0 SE8702550 D0 SE 8702550D0
Authority
SE
Sweden
Prior art keywords
gly
pro
val
pct
leu
Prior art date
Application number
SE8702550A
Other languages
English (en)
Inventor
Anders Grubb
Magnus Abrahamson
Jerzy Trojnar
Original Assignee
Anders Grubb
Magnus Abrahamson
Jerzy Trojnar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anders Grubb, Magnus Abrahamson, Jerzy Trojnar filed Critical Anders Grubb
Priority to SE8702550A priority Critical patent/SE8702550D0/sv
Publication of SE8702550D0 publication Critical patent/SE8702550D0/sv
Priority to PCT/SE1988/000334 priority patent/WO1988010266A1/en
Priority to EP88906175A priority patent/EP0418233A1/en
Priority to JP63505269A priority patent/JPH02503917A/ja
Priority to US07/435,463 priority patent/US5037957A/en
Priority to AU19604/88A priority patent/AU604944B2/en
Priority to NO89895008A priority patent/NO895008L/no
Priority to DK637489A priority patent/DK637489A/da
Priority to FI896029A priority patent/FI896029A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SE8702550A 1987-06-18 1987-06-18 Cysteinproteashemmare SE8702550D0 (sv)

Priority Applications (9)

Application Number Priority Date Filing Date Title
SE8702550A SE8702550D0 (sv) 1987-06-18 1987-06-18 Cysteinproteashemmare
PCT/SE1988/000334 WO1988010266A1 (en) 1987-06-18 1988-06-17 Cysteine proteinase inhibitor
EP88906175A EP0418233A1 (en) 1987-06-18 1988-06-17 Cysteine proteinase inhibitor
JP63505269A JPH02503917A (ja) 1987-06-18 1988-06-17 システインプロテイナーゼ阻害剤
US07/435,463 US5037957A (en) 1987-06-18 1988-06-17 Cysteine proteinase inhibitor
AU19604/88A AU604944B2 (en) 1987-06-18 1988-06-17 Cysteine proteinase inhibitor
NO89895008A NO895008L (no) 1987-06-18 1989-12-13 Cysteinproteasehemmer.
DK637489A DK637489A (da) 1987-06-18 1989-12-15 Cysteinproteinaseinhibitor
FI896029A FI896029A0 (fi) 1987-06-18 1989-12-15 Cysteinproteinas-inhibitor.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8702550A SE8702550D0 (sv) 1987-06-18 1987-06-18 Cysteinproteashemmare

Publications (1)

Publication Number Publication Date
SE8702550D0 true SE8702550D0 (sv) 1987-06-18

Family

ID=20368906

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8702550A SE8702550D0 (sv) 1987-06-18 1987-06-18 Cysteinproteashemmare

Country Status (7)

Country Link
US (1) US5037957A (sv)
EP (1) EP0418233A1 (sv)
JP (1) JPH02503917A (sv)
AU (1) AU604944B2 (sv)
FI (1) FI896029A0 (sv)
SE (1) SE8702550D0 (sv)
WO (1) WO1988010266A1 (sv)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5189144A (en) * 1989-04-28 1993-02-23 Takara Shuzo Co., Ltd. Human calpastatin-like polypeptide
US5444042A (en) * 1990-12-28 1995-08-22 Cortex Pharmaceuticals Method of treatment of neurodegeneration with calpain inhibitors
AU2548992A (en) * 1991-08-13 1993-03-16 Temple University - Of The Commonwealth System Of Higher Education Modulation of blood pressure and inhibition of platelet activation with kininogen fragment
IL112759A0 (en) * 1994-02-25 1995-05-26 Khepri Pharmaceuticals Inc Novel cysteine protease inhibitors
US5693617A (en) * 1994-03-15 1997-12-02 Proscript, Inc. Inhibitors of the 26s proteolytic complex and the 20s proteasome contained therein
US6660268B1 (en) 1994-03-18 2003-12-09 The President And Fellows Of Harvard College Proteasome regulation of NF-KB activity
US5703212A (en) * 1994-04-19 1997-12-30 Kanebo, Ltd. Preventive for circulatory diseases
US6083903A (en) 1994-10-28 2000-07-04 Leukosite, Inc. Boronic ester and acid compounds, synthesis and uses
US5905076A (en) * 1996-04-10 1999-05-18 National Research Council Of Canada 6-substituted amino-4-oxa-1-azabicyclo 3,2,0! heptan-7-one derivatives as cysteine protease inhibitors
WO1999038501A2 (en) 1998-02-02 1999-08-05 Trustees Of Tufts College Method of regulating glucose metabolism, and reagents related thereto
US6514941B1 (en) 1999-12-10 2003-02-04 Campina Melkunie B.V. Method of preparing a casein hydrolysate enriched in anti-hypertensive peptides
WO2003045228A2 (en) 2001-11-26 2003-06-05 Trustees Of Tufts College Methods for treating autoimmune disorders, and reagents related thereto
BR0307279A (pt) * 2002-01-29 2004-12-28 Wyeth Corp Métodos para fechar e abrir um semi-canal e uma célula, tecido orgãnico ou órgão, para prevenir ou tratar o estresse de tecido orgãnico ou órgão em um mamìfero, para aumentar a comunicação intracelular da junção com intervalo em uma célula, tecido orgãnico ou órgão, para tratamento de queimaduras, de tromboses, da acidose respitatória e metabólica, e da arritmia focal, para tratar e prevenir o dano de célula e tecido orgãnico resultante de nìveis elevados de glicose no sangue, para tratamento da fibrilação atrial crÈnica e da epilepsia, para criar composto candidatos que modulem a função de semi-canal, para citoproteger tecido orgãnico ou um órgão de um mamìfero em necessidade de tal tratamento, e para prevenir ou tratar o dano da reperfusão em um mamìfero
AU2003291356A1 (en) 2002-11-06 2004-06-03 Dana-Farber Cancer Institute, Inc. Methods and compositions for treating cancer using proteasome inhibitors
US20100048450A1 (en) 2005-10-07 2010-02-25 Klinken S Peter Sumoylation Control Agent and Uses Thereof
US20090258827A1 (en) 2006-04-07 2009-10-15 Biopharmica Ltd. Transcription Factor Modulator
ES2853204T3 (es) 2010-05-25 2021-09-15 Syndevrx Inc Inhibidores de MetAP2 conjugado con polímero, y métodos terapéuticos de uso de los mismos
US9895449B2 (en) 2010-05-25 2018-02-20 Syndevrx, Inc. Polymer-conjugated MetAP2 inhibitors, and therapeutic methods of use thereof
EA033912B1 (ru) 2013-04-10 2019-12-09 Синдевркс, Инк. ИНГИБИТОРЫ MetAP2 И СПОСОБЫ ЛЕЧЕНИЯ ОЖИРЕНИЯ
KR20180093995A (ko) 2015-12-10 2018-08-22 신데브알엑스, 인크. 푸마길롤 유도체 및 그의 다형체
KR20180093086A (ko) 2016-01-06 2018-08-20 론자 리미티드 개선된 생산을 위한 단백질 분해의 억제
WO2017123603A1 (en) 2016-01-11 2017-07-20 Syndevrx, Inc. Treatment for tumors driven by metabolic dysfunction
KR20200135410A (ko) 2018-03-20 2020-12-02 아브락시스 바이오사이언스, 엘엘씨 mTOR 억제제 및 알부민의 나노입자의 투여를 통한 중추 신경계 장애의 치료 방법
CN113453721A (zh) 2018-10-26 2021-09-28 辛德弗雷克斯公司 Metap2抑制剂的生物标志物及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4100117A (en) * 1977-04-21 1978-07-11 Eli Lilly And Company Somatostatin analogs and intermediates thereto

Also Published As

Publication number Publication date
EP0418233A1 (en) 1991-03-27
JPH02503917A (ja) 1990-11-15
US5037957A (en) 1991-08-06
AU1960488A (en) 1989-01-19
FI896029A0 (fi) 1989-12-15
AU604944B2 (en) 1991-01-03
WO1988010266A1 (en) 1988-12-29

Similar Documents

Publication Publication Date Title
SE8702550D0 (sv) Cysteinproteashemmare
EP0528858A4 (en) Inhibitors of dipeptidyl-aminopeptidase type iv
BR0012243A (pt) Triflúor butenos nematocidas
ITMI912457A1 (it) Policarbonati dioloterminati
IS1805B (is) Aðferð til að framleiða nýjar peptíðafleiður sem eru þrombíntálmar
ES2118254T3 (es) Sales de amonio polimericas reticuladas.
ES557733A0 (es) Procedimiento para preparar peptidos difluorcetonicos
DK1263471T3 (da) Antimikrobielle forbindelser og formuleringer
BG38487A3 (en) Method for preparing peptides
NO303783B1 (no) Substituerte aminofosfonatderivater og farmas°ytiske preparater derav
JPS56156289A (en) Metal chelate of 1,4-bis(substituted amino)- 5,8-dihydroxyanthraquinone
ATE178072T1 (de) Neuartige polypeptide und ihre verwendung
ATE121754T1 (de) Vakzine gegen bordetella.
HK1013951A1 (en) Production and use of anthelmintic agents and protective immunogens
DK0610078T3 (da) Cytotoksisk og antiviral forbindelse.
CA2188176A1 (fr) (oxo-1 alkyl) amino-2, deoxy-2 glucopyranoside de dihydroxy - 2,3 propyl, leur procede de preparation et leurs utilisations
DK0548177T3 (da) 5-Aminosalicylsyrederivater til terapi af kroniske inflammatoriske tarmsygdomme
BG35593A3 (en) Method for separating aminoacids in optical antipodes
NZ228023A (en) 24(r)-scymnol; preparatory processes and pharmaceutical compositions
GB9604518D0 (en) Novel compounds
IT8120307A0 (it) Disposizione per il trattamento termico di pezzi d'opera.
AU542310B2 (en) Glicentin related purified peptide having 30 amino acids
NO910664D0 (no) Fremgangsmaate ved fremstilling av lh-rh-analoger med temporaer og minimal beskyttelse.
FR2710845B1 (fr) Composition destinée à l'immunothérapie d'un cancer sécrétant l'hCG ou des fragments d'hCG.
IT1240645B (it) Procedimento per la fabbricazione di 7-dimetilamino-6-demetil-6- deossitetraciclina