SE8600355L - Forfarande for framstellning av 4,4-dialkyl-2-azetidinoner - Google Patents

Forfarande for framstellning av 4,4-dialkyl-2-azetidinoner

Info

Publication number: SE8600355L
Authority: SE; Sweden
Prior art keywords: azetidinones; dialkyl; preparing; procedure; amino
Prior art date: 1985-01-28

Application number

SE8600355A

Other languages

English (en)

Other versions

SE467824B (sv

SE8600355D0 (sv

Inventor

W A Slusarchyk

T Dejneka

W H Koster

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-01-28

Filing date

1986-01-27

Publication date

1986-07-29

1986-01-27 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1986-01-27 Publication of SE8600355D0 publication Critical patent/SE8600355D0/sv

1986-07-29 Publication of SE8600355L publication Critical patent/SE8600355L/sv

1992-09-21 Publication of SE467824B publication Critical patent/SE467824B/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
- C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
- C07D213/18—Salts thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Cephalosporin Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Pyridine Compounds (AREA)
Pyrane Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

SE8600355A 1985-01-28 1986-01-27 Foerfarande foer framstaellning av 4,4-dialkyl-2-azetidinoner SE467824B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/695,775 US4638061A (en)	1985-01-28	1985-01-28	[3S(Z)]-2-[[[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]-amino]oxy] acetic acid and intermediate

Publications (3)

Publication Number	Publication Date
SE8600355D0 SE8600355D0 (sv)	1986-01-27
SE8600355L true SE8600355L (sv)	1986-07-29
SE467824B SE467824B (sv)	1992-09-21

Family

ID=24794413

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
SE8600355A SE467824B (sv)	1985-01-28	1986-01-27	Foerfarande foer framstaellning av 4,4-dialkyl-2-azetidinoner
SE9002337A SE502442C2 (sv)	1985-01-28	1990-07-03	(3S)-3-amino-2-oxo-4,4-dimetyl-1-azetidinylsulfat samt ett förfarande för framställning av föreningen
SE9002338A SE468896B (sv)	1985-01-28	1990-07-03	Azetidinylderivat och foerfarande foer framstaellning daerav

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
SE9002337A SE502442C2 (sv)	1985-01-28	1990-07-03	(3S)-3-amino-2-oxo-4,4-dimetyl-1-azetidinylsulfat samt ett förfarande för framställning av föreningen
SE9002338A SE468896B (sv)	1985-01-28	1990-07-03	Azetidinylderivat och foerfarande foer framstaellning daerav

Country Status (35)

Country	Link
US (1)	US4638061A (sv)
JP (2)	JPH0780840B2 (sv)
KR (1)	KR900000675B1 (sv)
CN (1)	CN1014894B (sv)
AR (1)	AR242024A1 (sv)
AT (1)	AT389511B (sv)
AU (1)	AU588017B2 (sv)
BE (1)	BE904121A (sv)
CA (2)	CA1283924C (sv)
CH (3)	CH670825A5 (sv)
CS (1)	CS253740B2 (sv)
DD (3)	DD248592A5 (sv)
DE (1)	DE3602347A1 (sv)
DK (1)	DK39486A (sv)
EG (1)	EG17682A (sv)
ES (3)	ES8706112A1 (sv)
FI (1)	FI85022C (sv)
FR (1)	FR2576596B1 (sv)
GB (2)	GB2170201B (sv)
GR (1)	GR860239B (sv)
HU (1)	HU196367B (sv)
IE (2)	IE59629B1 (sv)
IL (1)	IL77661A (sv)
IT (1)	IT1190604B (sv)
LU (1)	LU86262A1 (sv)
NL (1)	NL8600136A (sv)
NO (1)	NO170014C (sv)
NZ (1)	NZ214836A (sv)
PH (3)	PH22425A (sv)
PL (3)	PL257668A1 (sv)
PT (1)	PT81914B (sv)
RO (1)	RO93483B (sv)
SE (3)	SE467824B (sv)
YU (2)	YU45760B (sv)
ZA (1)	ZA86302B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4751220A (en) *	1986-12-19	1988-06-14	E. R. Squibb & Sons, Inc.	Crystalline salts of [3S(Z)]-2[[[1-(2-amino-4-thiazolyl)-2-[[2,2-dimethyl-4-oxo-1-(sulfooxy)-3-azetidinyl]amino]-2-oxoethylidene]-amino]oxy]acetic acid
US5143913A (en) *	1988-04-04	1992-09-01	E. R. Squibb & Sons, Inc.	[3S(Z)]-3-[[(2-amino-4-thiazolyl)[[2-(hydroxyamino)-2-oxoethoxy]imino]acetyl]amino]-2,2-dimethyl-4-oxo-1-azetidinyl sulfate
EP0336667A3 (en) *	1988-04-04	1991-04-10	E.R. Squibb & Sons, Inc.	[3S(Z)]-3-[[(2-amino-4-thiazolyl)[[2-(hydroxyamino)-2-oxoethoxy]imino]acetyl]-amino]-2,2-dimethyl-4-oxo-1-azetidinyl sulfate
US4973747A (en) *	1989-08-15	1990-11-27	E. R. Squibb & Sons, Inc.	Process for preparing 3-hydroxy 2-keto acids
US8901293B2 (en) *	2005-12-07	2014-12-02	Basilea Pharmaceutica Ag	Useful combinations of monobactam antibiotics with beta-lactamase inhibitors
WO2017180794A1 (en)	2016-04-13	2017-10-19	Skyline Antiinfectives, Inc.	Deuterated o-sulfated beta-lactam hydroxamic acids and deuterated n-sulfated beta-lactams

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4337197A (en) *	1980-10-31	1982-06-29	E. R. Squibb & Sons, Inc.	O-sulfated β-lactam hydroxamic acids and intermediates
JPS58113174A (ja) *	1981-12-26	1983-07-05	Toyama Chem Co Ltd	新規なアゼチジン誘導体またはその塩類を含有する抗菌剤
JPS58194856A (ja) *	1982-05-10	1983-11-12	Yamanouchi Pharmaceut Co Ltd	新規２−アゼチジノン誘導体
JPS58206589A (ja) *	1982-05-26	1983-12-01	Yamanouchi Pharmaceut Co Ltd	２−アゼチジノン誘導体
US4565654A (en) *	1983-03-28	1986-01-21	University Of Notre Dame Du Lac	N-Acyloxy monocyclic β-lactams

1985
- 1985-01-28 US US06/695,775 patent/US4638061A/en not_active Expired - Fee Related
1986
- 1986-01-15 GB GB08600825A patent/GB2170201B/en not_active Expired
- 1986-01-15 ZA ZA86302A patent/ZA86302B/xx unknown
- 1986-01-15 NZ NZ214836A patent/NZ214836A/xx unknown
- 1986-01-15 CA CA000499611A patent/CA1283924C/en not_active Expired - Lifetime
- 1986-01-16 PH PH33290A patent/PH22425A/en unknown
- 1986-01-16 YU YU5886A patent/YU45760B/sh unknown
- 1986-01-17 AU AU52460/86A patent/AU588017B2/en not_active Ceased
- 1986-01-17 FR FR868600631A patent/FR2576596B1/fr not_active Expired
- 1986-01-20 FI FI860247A patent/FI85022C/sv not_active IP Right Cessation
- 1986-01-21 IL IL77661A patent/IL77661A/xx not_active IP Right Cessation
- 1986-01-22 LU LU86262A patent/LU86262A1/fr unknown
- 1986-01-22 NL NL8600136A patent/NL8600136A/xx not_active Application Discontinuation
- 1986-01-24 IE IE20586A patent/IE59629B1/en not_active IP Right Cessation
- 1986-01-24 IE IE930750A patent/IE930750L/xx unknown
- 1986-01-26 EG EG35/86A patent/EG17682A/xx active
- 1986-01-27 HU HU86375A patent/HU196367B/hu not_active IP Right Cessation
- 1986-01-27 DE DE19863602347 patent/DE3602347A1/de not_active Ceased
- 1986-01-27 CH CH2358/88A patent/CH670825A5/fr not_active IP Right Cessation
- 1986-01-27 CH CH305/86A patent/CH667872A5/fr not_active IP Right Cessation
- 1986-01-27 ES ES551252A patent/ES8706112A1/es not_active Expired
- 1986-01-27 KR KR1019860000501A patent/KR900000675B1/ko not_active Expired
- 1986-01-27 NO NO860273A patent/NO170014C/no unknown
- 1986-01-27 PT PT81914A patent/PT81914B/pt not_active IP Right Cessation
- 1986-01-27 CH CH2357/88A patent/CH670824A5/fr not_active IP Right Cessation
- 1986-01-27 RO RO122011A patent/RO93483B/ro unknown
- 1986-01-27 SE SE8600355A patent/SE467824B/sv not_active IP Right Cessation
- 1986-01-27 DK DK39486A patent/DK39486A/da not_active Application Discontinuation
- 1986-01-28 CN CN86100736A patent/CN1014894B/zh not_active Expired
- 1986-01-28 AR AR86302968A patent/AR242024A1/es active
- 1986-01-28 BE BE0/216191A patent/BE904121A/fr not_active IP Right Cessation
- 1986-01-28 PL PL25766886A patent/PL257668A1/xx unknown
- 1986-01-28 JP JP61017708A patent/JPH0780840B2/ja not_active Expired - Lifetime
- 1986-01-28 CS CS86625A patent/CS253740B2/cs unknown
- 1986-01-28 DD DD86292942A patent/DD248592A5/de unknown
- 1986-01-28 GR GR860239A patent/GR860239B/el unknown
- 1986-01-28 PL PL1986262318A patent/PL262318A1/xx unknown
- 1986-01-28 AT AT0020386A patent/AT389511B/de not_active IP Right Cessation
- 1986-01-28 IT IT19206/86A patent/IT1190604B/it active
- 1986-01-28 DD DD86286545A patent/DD241600A5/de not_active IP Right Cessation
- 1986-01-28 DD DD86292943A patent/DD248584A5/de unknown
- 1986-01-28 PL PL1986262317A patent/PL149156B1/pl unknown
- 1986-09-09 ES ES557056A patent/ES8800897A1/es not_active Expired
- 1986-09-09 ES ES557057A patent/ES8801917A1/es not_active Expired
1987
- 1987-02-18 PH PH34872A patent/PH23093A/en unknown
- 1987-02-18 PH PH34871A patent/PH23084A/en unknown
- 1987-09-08 YU YU01670/87A patent/YU167087A/xx unknown
1988
- 1988-01-08 GB GB08800425A patent/GB2198133B/en not_active Expired
1989
- 1989-11-24 CA CA000615565A patent/CA1279322C/en not_active Expired - Lifetime
1990
- 1990-07-03 SE SE9002337A patent/SE502442C2/sv not_active IP Right Cessation
- 1990-07-03 SE SE9002338A patent/SE468896B/sv not_active IP Right Cessation
1995
- 1995-02-21 JP JP7032368A patent/JPH0853404A/ja active Pending

Also Published As

Publication number	Publication date
YU45760B (sh)	1992-07-20
KR860005812A (ko)	1986-08-13
AU588017B2 (en)	1989-09-07
GR860239B (en)	1986-05-28
ATA20386A (de)	1989-05-15
YU5886A (en)	1988-02-29
HU196367B (en)	1988-11-28
PH23084A (en)	1989-04-10
CS253740B2 (en)	1987-12-17
LU86262A1 (fr)	1986-08-04
CA1283924C (en)	1991-05-07
FR2576596A1 (fr)	1986-08-01
GB2198133B (en)	1989-01-11
IL77661A (en)	1989-06-30
SE9002338D0 (sv)	1990-07-03
AR242024A1 (es)	1993-02-26
YU167087A (en)	1988-04-30
JPH0780840B2 (ja)	1995-08-30
ES557056A0 (es)	1987-12-01
ES8801917A1 (es)	1988-03-01
DK39486A (da)	1986-07-29
SE467824B (sv)	1992-09-21
NZ214836A (en)	1988-10-28
CA1279322C (en)	1991-01-22
PL262317A1 (en)	1987-09-07
RO93483B (ro)	1988-01-01
CN1014894B (zh)	1991-11-27
US4638061A (en)	1987-01-20
SE9002338L (sv)	1990-07-03
EG17682A (en)	1990-10-30
RO93483A (ro)	1987-12-31
IE860205L (en)	1986-07-28
GB8800425D0 (en)	1988-02-10
IT8619206A0 (it)	1986-01-28
ES557057A0 (es)	1988-03-01
DE3602347A1 (de)	1986-07-31
BE904121A (fr)	1986-05-15
AU5246086A (en)	1986-07-31
CN86100736A (zh)	1986-10-22
FI85022C (sv)	1992-02-25
NO170014C (no)	1992-09-02
AT389511B (de)	1989-12-27
GB2170201B (en)	1989-01-11
CH667872A5 (fr)	1988-11-15
NO860273L (no)	1986-07-29
IT1190604B (it)	1988-02-16
FR2576596B1 (fr)	1989-12-15
ES551252A0 (es)	1987-06-01
ES8800897A1 (es)	1987-12-01
CH670824A5 (sv)	1989-07-14
IE59629B1 (en)	1994-03-09
SE9002337D0 (sv)	1990-07-03
IE930750L (en)	1986-07-28
JPS61176563A (ja)	1986-08-08
SE468896B (sv)	1993-04-05
FI860247L (fi)	1986-07-29
PT81914A (en)	1986-02-01
SE502442C2 (sv)	1995-10-16
KR900000675B1 (ko)	1990-02-02
PL257668A1 (en)	1987-03-09
HUT40407A (en)	1986-12-28
DD248584A5 (de)	1987-08-12
ZA86302B (en)	1986-08-27
SE8600355D0 (sv)	1986-01-27
PL262318A1 (en)	1987-09-07
SE9002337L (sv)	1990-07-03
NL8600136A (nl)	1986-08-18
PH22425A (en)	1988-09-12
CH670825A5 (sv)	1989-07-14
PH23093A (en)	1989-04-10
GB2198133A (en)	1988-06-08
GB2170201A (en)	1986-07-30
NO170014B (no)	1992-05-25
ES8706112A1 (es)	1987-06-01
FI85022B (fi)	1991-11-15
DD241600A5 (de)	1986-12-17
FI860247A0 (fi)	1986-01-20
DK39486D0 (da)	1986-01-27
PT81914B (pt)	1987-11-30
JPH0853404A (ja)	1996-02-27
DD248592A5 (de)	1987-08-12
PL149156B1 (en)	1990-01-31

Publication	Publication Date	Title
AU560179B2 (en)	1987-04-02	Hypoglycemic thiazolidinedione derivatives
NO175371C (no)	1994-10-05	Analogifremgangsmåte for fremstilling av terapeutisk aktive aminosyrederivater
NO170330C (no)	1992-10-07	Fremgangsmaate for fremstilling av vesentlig optisk rent monohydrat av s-(-)-propyl-2',6'-pipekoloksylididhydroklorid
NO175976C (no)	1995-01-11	Analogifremgangsmåte for fremstilling av terapeutisk aktive 4-(1,6-dihydro-6-okso-pyridazinyl-3-oksy)-3-kromanolderivater
SE8600355L (sv)	1986-07-29	Forfarande for framstellning av 4,4-dialkyl-2-azetidinoner
FI900145A0 (sv)	1990-01-11	Förfarande för framställning av farmaceutiskt användbara 1,1-dioxo-cefem-4-karbotiolsyraderivat
NL193639B (nl)	2000-01-03	Farmaceutisch aanvaardbare zouten van [3S(Z)]-2[[[1-(2-aminothiazolyl-4)-2-[[2,2-dimethyl-4-oxo-1-(sulfooxy) -3-azetidinyl]amino]-2-oxoethylideen]amino]-oxy]azijnzuur.
AU4545289A (en)	1990-05-31	2-azabicyclo(2.2.1)hept-5-ene-2-acetic acid, derivatives thereof and related compounds, process for the preparation of said compounds and the use of said compounds for the manufacture of n-phosphonomethylglycine
FI93216C (sv)	1995-03-10	Analogiförfarande för framställning av terapeutiskt användbara 1,3-dioxanalkensyraderivat
DE3374008D1 (en)	1987-11-12	Process for the preparation of azetidine sulfonic acids
AU1509388A (en)	1988-10-27	Substituted quinoxalyl-imidazolidine-2,4-diones, processes for their preparation, their use as medicaments and pharmaceutical preparations
IL83495A0 (en)	1988-01-31	Oxirane pseudooligosaccharides,a process for their preparation,and pharmaceutical preparations containing them
AU3620089A (en)	1989-12-14	New process for the preparation of n-(23-vinblastinoyl) derivatives of 1-amino-methyl-phosphonic acid
GR3018126T3 (en)	1996-02-29	4-[(Thiophene-2-carbonyl)oxy]pyrrolidine-2-carboxylic acid, its preparation and its use as anti-inflammatory and anti-dystrophic agent.
NO943458D0 (no)	1994-09-16	Fremgangsmåte for fremstilling av terapeutisk aktivt amphiregulin
IT8619931A1 (it)	1987-09-28	Procedimento per la preparazione della 1-(N-metilamidino)-3-{2,6-dimetilfenil)urea e dei suoi sali farmaceuticamente accettabili

Legal Events

Date	Code	Title	Description
1995-01-31	NAL	Patent in force	Ref document number: 8600355-5 Format of ref document f/p: F
2001-09-10	NUG	Patent has lapsed	Ref document number: 8600355-5 Format of ref document f/p: F

Date

Code

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1995-01-31

NAL

Patent in force

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2001-09-10

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