[go: up one dir, main page]

SE8302517L - Forfarande for framstellning av antibiotikum c-15003 p-0 (maytansinol) - Google Patents

Forfarande for framstellning av antibiotikum c-15003 p-0 (maytansinol)

Info

Publication number
SE8302517L
SE8302517L SE8302517A SE8302517A SE8302517L SE 8302517 L SE8302517 L SE 8302517L SE 8302517 A SE8302517 A SE 8302517A SE 8302517 A SE8302517 A SE 8302517A SE 8302517 L SE8302517 L SE 8302517L
Authority
SE
Sweden
Prior art keywords
antibiotic
preparation
maytansinol
procedure
agent
Prior art date
Application number
SE8302517A
Other languages
English (en)
Other versions
SE446004B (sv
SE8302517D0 (sv
Inventor
E Higashide
M Asai
S Tanida
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP52037166A external-priority patent/JPS6034556B2/ja
Priority claimed from US05/811,448 external-priority patent/US4162940A/en
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of SE8302517L publication Critical patent/SE8302517L/sv
Publication of SE8302517D0 publication Critical patent/SE8302517D0/sv
Publication of SE446004B publication Critical patent/SE446004B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Claims (1)

1. Patenkrav Forfarande fOr framstHlining av en forening med formeln av CH3 OCH3 k N.nretecknat av aft man underkastar antibiotikan C-15003 med den allmanna formeln i vilken R hetecknar CH3 OO-CO2-CO2-CH3 eller 3 CO3 -CO-CU -CU , reduktiv hydrolys.
SE8302517A 1977-03-31 1983-05-03 Forfarande for framstellning av antibiotikum c-15003 p-o (maytansinol) SE446004B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP52037166A JPS6034556B2 (ja) 1977-03-31 1977-03-31 抗生物質ｃ−１５００３
US05/811,448 US4162940A (en) 1977-03-31 1977-06-29 Method for producing Antibiotic C-15003 by culturing nocardia

Publications (3)

Publication Number Publication Date
SE8302517L true SE8302517L (sv) 1983-05-03
SE8302517D0 SE8302517D0 (sv) 1983-05-03
SE446004B SE446004B (sv) 1986-08-04

Family

ID=26376254

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7711542A SE442873B (sv) 1977-03-31 1977-10-13 Forfarande for framstellning av ett nytt antibiotikum c-15003 med angiven formel genom odling av nocardia no c-15003 (ifo 13726, ferm 3992, atcc 31281)
SE8302517A SE446004B (sv) 1977-03-31 1983-05-03 Forfarande for framstellning av antibiotikum c-15003 p-o (maytansinol)

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7711542A SE442873B (sv) 1977-03-31 1977-10-13 Forfarande for framstellning av ett nytt antibiotikum c-15003 med angiven formel genom odling av nocardia no c-15003 (ifo 13726, ferm 3992, atcc 31281)

Country Status (16)

Country Link
CA (1) CA1107212A (sv)
CS (1) CS214749B2 (sv)
DE (1) DE2746209A1 (sv)
DK (1) DK458877A (sv)
ES (2) ES463207A1 (sv)
GB (1) GB1586688A (sv)
GR (1) GR66051B (sv)
HU (1) HU178359B (sv)
IE (1) IE46064B1 (sv)
IT (1) IT1094308B (sv)
NL (1) NL188102C (sv)
PH (2) PH13381A (sv)
PL (2) PL124349B1 (sv)
PT (1) PT67854B (sv)
SE (2) SE442873B (sv)
YU (2) YU245377A (sv)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5562090A (en) * 1978-10-27 1980-05-10 Takeda Chem Ind Ltd Novel maytansinoid compound and its preparation
JPS55102583A (en) * 1979-01-31 1980-08-05 Takeda Chem Ind Ltd 20-acyloxy-20-demethylmaytansinoid compound
JPS5645483A (en) * 1979-09-19 1981-04-25 Takeda Chem Ind Ltd C-15003phm and its preparation
DE19940131B4 (de) * 1998-08-24 2004-12-02 Pfefferle, Christoph, Dr. Verfahren und Vorrichtung zur Gewinnung von biologisch aktiven Substanzen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1336399A (en) * 1971-06-24 1973-11-07 Lepetit Spa 3-formylrifamycin sv derivatives
DE2241418A1 (de) * 1972-08-23 1974-03-07 S Morris Kupchan Antileukaemische ansamakrolide

Also Published As

Publication number Publication date
CA1107212A (en) 1981-08-18
PL122289B1 (en) 1982-07-31
SE7711542L (sv) 1978-10-01
IT7821818A0 (it) 1978-03-30
NL188102B (nl) 1991-11-01
IT1094308B (it) 1985-07-26
GB1586688A (en) 1981-03-25
PT67854A (en) 1978-04-01
HU178359B (en) 1982-04-28
IE46064L (en) 1978-09-30
SE446004B (sv) 1986-08-04
IE46064B1 (en) 1983-02-09
NL188102C (nl) 1992-04-01
SE8302517D0 (sv) 1983-05-03
DE2746209C2 (sv) 1990-10-31
PH13381A (en) 1980-03-25
YU245377A (en) 1983-01-21
YU178582A (en) 1984-08-31
GR66051B (sv) 1981-01-14
NL7711274A (nl) 1978-10-03
DK458877A (da) 1978-10-01
ES472230A1 (es) 1979-04-01
PL201541A1 (pl) 1978-10-09
PT67854B (en) 1980-05-05
PL124349B1 (en) 1983-01-31
PH15985A (en) 1983-05-18
DE2746209A1 (de) 1978-10-19
ES463207A1 (es) 1979-01-01
SE442873B (sv) 1986-02-03
CS214749B2 (en) 1982-05-28

Similar Documents

Publication Publication Date Title
GB1453425A (en) 2-oxo-tetrahydropyran derivatives and fermentative process for producing the same
SE8001339L (sv) Antihyperkolesteraemiskt medel, monakolin k och framstellning derav
ES442948A1 (es) Un procedimiento para preparar eteres de calcona.
DE3066026D1 (en) A method for the production of antibiotic c-15003 p-3
CA2045553A1 (en) Process for the Preparation of Vinyl Ethers
SE8302517L (sv) Forfarande for framstellning av antibiotikum c-15003 p-0 (maytansinol)
GB1514219A (en) Process for the preparation of moenomycin
GB1532551A (en) Furo(3,4-6)furone derivatives and their preparation
KR890014457A (ko) 신규 아족시 화합물 및 그의 제조방법
DE3675424D1 (de) Valiolaminderivate und ihre herstellung.
IE39919L (en) Rifamycins
DK578083A (da) Antibiotika benaevnt a51568 faktor a og b og fremgangsmaade til fremstilling heraf
JPS52108092A (en) Preparation of bicyclomycin
JPS55164671A (en) Azetidine derivative and its preparation
JPS55105667A (en) Gluconic lactam derivative
JPS51122071A (en) A process for preparing novel chromone derivatives
JPS57139079A (en) 8,9-epoxy derivative of antibiotic substance b-41 and its preparation
JPS5279082A (en) Preparation of anti-tumor compound
JPS5420197A (en) Preparation of antibiotic substance-sf-837m1
JPS51138660A (en) Process for prep aration of polycyclic urethanes
JPS5212990A (en) Preparation of de-3936
JPS5462390A (en) Preparation of physostigmine
JPS55118490A (en) Demethylmaytansinoid compound and its preparation
ES2026548T3 (es) Un procedimiento para preparar penemos.
JPS54119468A (en) Novel antibiotic, nanaomycin e and its preparation

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8302517-1

Effective date: 19940510

Format of ref document f/p: F