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SE8302483D0 - Forfarande vid rening av biologiskt aktiva substanser - Google Patents

Forfarande vid rening av biologiskt aktiva substanser

Info

Publication number
SE8302483D0
SE8302483D0 SE8302483A SE8302483A SE8302483D0 SE 8302483 D0 SE8302483 D0 SE 8302483D0 SE 8302483 A SE8302483 A SE 8302483A SE 8302483 A SE8302483 A SE 8302483A SE 8302483 D0 SE8302483 D0 SE 8302483D0
Authority
SE
Sweden
Prior art keywords
pct
substance
purification
biologically active
procedure
Prior art date
Application number
SE8302483A
Other languages
English (en)
Other versions
SE8302483L (sv
Inventor
S J-G Gustafsson
T G I Ling
P I Hedman
B G Mattiasson
Original Assignee
Pharmacia Fine Chemicals Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Fine Chemicals Ab filed Critical Pharmacia Fine Chemicals Ab
Priority to SE8302483A priority Critical patent/SE8302483L/sv
Publication of SE8302483D0 publication Critical patent/SE8302483D0/sv
Priority to EP84902095A priority patent/EP0140966B1/en
Priority to PCT/SE1984/000159 priority patent/WO1984004309A1/en
Priority to US06/681,995 priority patent/US4579661A/en
Priority to AT84902095T priority patent/ATE30047T1/de
Priority to DE8484902095T priority patent/DE3466558D1/de
Priority to JP59501920A priority patent/JPS60501209A/ja
Publication of SE8302483L publication Critical patent/SE8302483L/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D12/00—Displacing liquid, e.g. from wet solids or from dispersions of liquids or from solids in liquids, by means of another liquid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361—Ion-exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
    • B01D15/3804—Affinity chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J39/00—Cation exchange; Use of material as cation exchangers; Treatment of material for improving the cation exchange properties
    • B01J39/26—Cation exchangers for chromatographic processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/79—Transferrins, e.g. lactoferrins, ovotransferrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/32—Nucleotides having a condensed ring system containing a six-membered ring having two N-atoms in the same ring, e.g. purine nucleotides, nicotineamide-adenine dinucleotide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
SE8302483A 1983-05-02 1983-05-02 Forfarande vid rening av biologiskt aktiva substanser SE8302483L (sv)

Priority Applications (7)

Application Number Priority Date Filing Date Title
SE8302483A SE8302483L (sv) 1983-05-02 1983-05-02 Forfarande vid rening av biologiskt aktiva substanser
EP84902095A EP0140966B1 (en) 1983-05-02 1984-04-27 Process in the purification of biologically active substances
PCT/SE1984/000159 WO1984004309A1 (en) 1983-05-02 1984-04-27 Process in the purification of biologically active substances
US06/681,995 US4579661A (en) 1983-05-02 1984-04-27 Process in the purification of biologically active substances
AT84902095T ATE30047T1 (de) 1983-05-02 1984-04-27 Verfahren zur reinigung biologischer aktivsubstanzen.
DE8484902095T DE3466558D1 (en) 1983-05-02 1984-04-27 Process in the purification of biologically active substances
JP59501920A JPS60501209A (ja) 1983-05-02 1984-04-27 生物学的活性物質の精製方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8302483A SE8302483L (sv) 1983-05-02 1983-05-02 Forfarande vid rening av biologiskt aktiva substanser

Publications (2)

Publication Number Publication Date
SE8302483D0 true SE8302483D0 (sv) 1983-05-02
SE8302483L SE8302483L (sv) 1984-11-03

Family

ID=20351033

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8302483A SE8302483L (sv) 1983-05-02 1983-05-02 Forfarande vid rening av biologiskt aktiva substanser

Country Status (6)

Country Link
US (1) US4579661A (sv)
EP (1) EP0140966B1 (sv)
JP (1) JPS60501209A (sv)
DE (1) DE3466558D1 (sv)
SE (1) SE8302483L (sv)
WO (1) WO1984004309A1 (sv)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE440699B (sv) * 1984-02-06 1985-08-12 Pharmacia Ab Sett att medelst isotransferrinbestemning uppskatta en individs alkoholkonsumtion
DE3527268A1 (de) * 1985-07-30 1987-02-05 Biotechnolog Forschung Gmbh Verfahren zur reinigung und gegebenenfalls gewinnung von formiat-dehydrogenase (fdh) aus candida boidinii und fdh-haltiges produkt
SE462100B (sv) * 1985-08-08 1990-05-07 Perstorp Ab Komposition och dess anvaendning i ett tvaa- eller flerfassystem
US4629567A (en) * 1986-03-07 1986-12-16 Smithkline-Rit Alpha-1-antiprotease purification
SE8701962D0 (sv) * 1987-05-13 1987-05-13 Bo Hakan Nygren Sett att isolera och/eller bestemma halten av ett organiskt emne genom kovalent koppling av en for emnet specifik motreaktant till ytadsorberad, hydrofoberad vattenloslig polymer
JP2761881B2 (ja) * 1988-03-10 1998-06-04 チッソ株式会社 抗体を固定化したアフイニテイクロマトグラフイ用担体
US5597485A (en) * 1988-05-13 1997-01-28 Vilmax S.A. Process for separating proteins
IE883226L (en) * 1988-10-25 1990-04-25 Dna Prep Galway Ltd S 22 Separation of nucleic acids from protein material using¹cation exchangers
US5043062A (en) * 1989-02-21 1991-08-27 Eastman Kodak Company High performance affinity chromatography column comprising non-porous, nondisperse polymeric packing material
US5274081A (en) * 1989-09-20 1993-12-28 Immuno A.G. Complex suitable for carrying out a method of purifying pre-S hepatitis B surface antigen
US5576175A (en) * 1989-09-20 1996-11-19 Immuno Aktiengesellschaft Complex suitable for carrying out a method of purifying pre-S hepatitis B surface antigen
US4980065A (en) * 1989-10-18 1990-12-25 Lehigh University Separation of mixtures by aqueous two-phase systems
US5078886A (en) * 1989-10-18 1992-01-07 Lehigh University Separation of mixtures by two-phase systems
US5093254A (en) * 1990-01-23 1992-03-03 The United States Of America, As Represented By The Secretary Of Commerce Aqueous two-phase protein extraction
DK159291D0 (da) * 1991-09-12 1991-09-12 Joergen Folkersen Fremgangsmaade til paavisning af et stof indeholdt i en biologisk vaeske
US5407810A (en) * 1993-08-20 1995-04-18 Genentech, Inc. Aqueous multiple-phase isolation of polypeptide
US5882520A (en) * 1995-10-26 1999-03-16 The University Of Montana Use of arabinogalactan in aqueous two phase extractions
DE19943374A1 (de) 1999-09-10 2001-03-29 Max Planck Gesellschaft Verfahren zum Anbinden von Nukleinsäuren an eine Festphase
WO2006003134A1 (en) * 2004-06-29 2006-01-12 Ares Trading S.A. Process for the purification of il-18 binding protein
CN118914420B (zh) * 2024-07-19 2025-01-28 南京鼓楼医院 一种血浆中蛋白的质谱检测前处理方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2252351A2 (en) * 1973-11-28 1975-06-20 Air Liquide Isolation of enzymes by selective extraction - partition of polyinhibitor-enzyme complex between water and polyethylene glycol
US3996132A (en) * 1974-07-18 1976-12-07 Ortho Pharmaceutical Corporation Purification of utero-evacuant extracts from plant substances
DE2500076C3 (de) * 1975-01-02 1982-11-18 SCHURA Blutderivate GmbH & Co KG, 4150 Krefeld Verfahren zur Gewinnung von intravenös-verträglichen Gammaglobulinen
DE2712344C2 (de) * 1977-03-21 1982-09-23 Hans Dr. 4803 Steinhagen Bünemann Löslicher Komplexbildner für die affinitätsspezifische Trennung von Nukleinsäuren
DE2815161C2 (de) * 1978-04-07 1984-11-22 Klöckner-Humboldt-Deutz AG, 5000 Köln Verfahren und Vorrichtung zur Herstellung eines hydraulischen Bindemittels
US4268395A (en) * 1978-10-04 1981-05-19 Babcock-Brown Boveri Reaktor Gmbh Extraction by solid stabilized emulsions
GB2039268B (en) * 1978-12-15 1983-01-19 Exxon Research Engineering Co Metal extraction by solid-liquid agglomerates
US4464165A (en) * 1980-11-24 1984-08-07 American Hoechst Corporation Material and method for removing immunoglobulins from whole blood

Also Published As

Publication number Publication date
SE8302483L (sv) 1984-11-03
WO1984004309A1 (en) 1984-11-08
US4579661A (en) 1986-04-01
JPS60501209A (ja) 1985-08-01
EP0140966B1 (en) 1987-09-30
DE3466558D1 (en) 1987-11-05
EP0140966A1 (en) 1985-05-15

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