SE8205849L - NEW FUROBENZZEPINES, THEIR PREPARATION AND USE - Google Patents
NEW FUROBENZZEPINES, THEIR PREPARATION AND USEInfo
- Publication number
- SE8205849L SE8205849L SE8205849A SE8205849A SE8205849L SE 8205849 L SE8205849 L SE 8205849L SE 8205849 A SE8205849 A SE 8205849A SE 8205849 A SE8205849 A SE 8205849A SE 8205849 L SE8205849 L SE 8205849L
- Authority
- SE
- Sweden
- Prior art keywords
- sleep
- furobenzzepines
- preparation
- new
- furobenzazepine
- Prior art date
Links
- RRAYZOWGWUYJGA-UHFFFAOYSA-N 4-piperazin-1-yl-9H-furo[2,3-i][1]benzazepine Chemical class N1(CCNCC1)C=1C=CN=C2C(C=1)=CC=C1C2=CCO1 RRAYZOWGWUYJGA-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000012458 free base Substances 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 239000003176 neuroleptic agent Substances 0.000 abstract 1
- 230000000701 neuroleptic effect Effects 0.000 abstract 1
- 230000001737 promoting effect Effects 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 230000007958 sleep Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
4-Piperazinyl-Furobenzazepine derivatives in free base form or in pharmaceutically acceptable acid addition salt form are useful as neuroleptic, anti-depressant, sleep-inducing, sleep- promoting and sleep-prolonging agents.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH662881A CH646974A5 (en) | 1981-10-16 | 1981-10-16 | Furobenzazepines, their preparation and use |
CH207782A CH650509A5 (en) | 1982-04-05 | 1982-04-05 | Furobenzazepines, their preparation and use |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8205849D0 SE8205849D0 (en) | 1982-10-14 |
SE8205849L true SE8205849L (en) | 1983-04-17 |
Family
ID=25689444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8205849A SE8205849L (en) | 1981-10-16 | 1982-10-14 | NEW FUROBENZZEPINES, THEIR PREPARATION AND USE |
Country Status (16)
Country | Link |
---|---|
AU (1) | AU8936982A (en) |
BE (1) | BE894623A (en) |
CA (1) | CA1193596A (en) |
DE (1) | DE3236937A1 (en) |
DK (1) | DK457082A (en) |
ES (1) | ES516489A0 (en) |
FI (1) | FI823437L (en) |
FR (1) | FR2514767A1 (en) |
GB (1) | GB2107711B (en) |
HU (1) | HU189184B (en) |
IT (1) | IT1189389B (en) |
NL (1) | NL8203954A (en) |
NZ (1) | NZ202170A (en) |
PH (1) | PH20263A (en) |
PT (1) | PT75677A (en) |
SE (1) | SE8205849L (en) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0001401A1 (en) * | 1977-09-29 | 1979-04-18 | Sandoz Ag | Thienobenzazepine derivatives, processes for their production and pharmaceutical compositions containing them |
-
1982
- 1982-10-06 FR FR8216847A patent/FR2514767A1/en active Granted
- 1982-10-06 DE DE19823236937 patent/DE3236937A1/en not_active Withdrawn
- 1982-10-07 BE BE1/10604A patent/BE894623A/en not_active IP Right Cessation
- 1982-10-08 FI FI823437A patent/FI823437L/en not_active Application Discontinuation
- 1982-10-12 GB GB08229098A patent/GB2107711B/en not_active Expired
- 1982-10-13 NL NL8203954A patent/NL8203954A/en not_active Application Discontinuation
- 1982-10-14 ES ES82516489A patent/ES516489A0/en active Granted
- 1982-10-14 AU AU89369/82A patent/AU8936982A/en not_active Abandoned
- 1982-10-14 CA CA000413420A patent/CA1193596A/en not_active Expired
- 1982-10-14 DK DK457082A patent/DK457082A/en not_active Application Discontinuation
- 1982-10-14 NZ NZ202170A patent/NZ202170A/en unknown
- 1982-10-14 SE SE8205849A patent/SE8205849L/en not_active Application Discontinuation
- 1982-10-15 PT PT75677A patent/PT75677A/en unknown
- 1982-10-15 IT IT49285/82A patent/IT1189389B/en active
- 1982-10-15 HU HU823284A patent/HU189184B/en not_active IP Right Cessation
- 1982-10-18 PH PH27997A patent/PH20263A/en unknown
Also Published As
Publication number | Publication date |
---|---|
GB2107711B (en) | 1985-04-17 |
AU8936982A (en) | 1983-04-21 |
ES8401483A1 (en) | 1983-12-16 |
PH20263A (en) | 1986-11-14 |
BE894623A (en) | 1983-04-07 |
FI823437L (en) | 1983-04-17 |
CA1193596A (en) | 1985-09-17 |
PT75677A (en) | 1982-11-01 |
IT1189389B (en) | 1988-02-04 |
FR2514767B1 (en) | 1984-01-27 |
GB2107711A (en) | 1983-05-05 |
NL8203954A (en) | 1983-05-16 |
FR2514767A1 (en) | 1983-04-22 |
DE3236937A1 (en) | 1983-05-05 |
DK457082A (en) | 1983-04-17 |
FI823437A0 (en) | 1982-10-08 |
IT8249285A0 (en) | 1982-10-15 |
ES516489A0 (en) | 1983-12-16 |
HU189184B (en) | 1986-06-30 |
SE8205849D0 (en) | 1982-10-14 |
NZ202170A (en) | 1985-11-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAV | Patent application has lapsed |
Ref document number: 8205849-6 |