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SE8204244L - Kristalliserad kolhydratsmatris for biologiskt aktiva substanser - Google Patents

Kristalliserad kolhydratsmatris for biologiskt aktiva substanser

Info

Publication number
SE8204244L
SE8204244L SE8204244A SE8204244A SE8204244L SE 8204244 L SE8204244 L SE 8204244L SE 8204244 A SE8204244 A SE 8204244A SE 8204244 A SE8204244 A SE 8204244A SE 8204244 L SE8204244 L SE 8204244L
Authority
SE
Sweden
Prior art keywords
biologically active
active substances
carbohydrate matrix
crystallized carbohydrate
crystallized
Prior art date
Application number
SE8204244A
Other languages
English (en)
Other versions
SE8204244D0 (sv
Inventor
Ulf Schroder
Original Assignee
Ulf Schroder
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ulf Schroder filed Critical Ulf Schroder
Priority to SE8204244A priority Critical patent/SE8204244L/sv
Publication of SE8204244D0 publication Critical patent/SE8204244D0/sv
Priority to JP58502406A priority patent/JPS59501213A/ja
Priority to PCT/SE1983/000268 priority patent/WO1984000294A1/en
Priority to US06/789,933 priority patent/US4713249A/en
Priority to EP83902308A priority patent/EP0113749B1/en
Priority to AU17760/83A priority patent/AU567434B2/en
Priority to AT83902308T priority patent/ATE34659T1/de
Priority to DE8383902308T priority patent/DE3376797D1/de
Publication of SE8204244L publication Critical patent/SE8204244L/sv
Priority to NO840676A priority patent/NO840676L/no
Priority to DK95284A priority patent/DK95284A/da
Priority to FI840923A priority patent/FI840923A/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SE8204244A 1981-11-12 1982-07-09 Kristalliserad kolhydratsmatris for biologiskt aktiva substanser SE8204244L (sv)

Priority Applications (11)

Application Number Priority Date Filing Date Title
SE8204244A SE8204244L (sv) 1982-07-09 1982-07-09 Kristalliserad kolhydratsmatris for biologiskt aktiva substanser
DE8383902308T DE3376797D1 (en) 1982-07-09 1983-07-04 A process of preparing a crystallised carbohydrate matrix for biologically active substances
EP83902308A EP0113749B1 (en) 1982-07-09 1983-07-04 A process of preparing a crystallised carbohydrate matrix for biologically active substances
PCT/SE1983/000268 WO1984000294A1 (en) 1982-07-09 1983-07-04 A crystallised carbohydrate matrix for biologically active substances, a process of preparing said matrix, and the use thereof
US06/789,933 US4713249A (en) 1981-11-12 1983-07-04 Crystallized carbohydrate matrix for biologically active substances, a process of preparing said matrix, and the use thereof
JP58502406A JPS59501213A (ja) 1982-07-09 1983-07-04 生物学的活性物質用の結晶化炭水化物マトリックス、該マトリックスの製造方法、及びその使用
AU17760/83A AU567434B2 (en) 1982-07-09 1983-07-04 A crystallised carbohydrate matrix for biologically active substances, a process of preparing said matrix, and the use thereof
AT83902308T ATE34659T1 (de) 1982-07-09 1983-07-04 Herstellung einer kristallisierten kohlenwasserstoffmatritze fuer biologisch-aktive substanzen.
NO840676A NO840676L (no) 1982-07-09 1984-02-22 Krystallisert karbohydratmatrise for biologisk aktive stoffer, fremgangsmaate for fremstilling av matrisen og dens anvendelse
DK95284A DK95284A (da) 1982-07-09 1984-02-23 Krystalliseret kulhydratmatrix for biologisk aktive stoffer, fremgangsmaade til fremstilling deraf samt dens anvendelse
FI840923A FI840923A (fi) 1982-07-09 1984-03-07 Kristalliserad kolhydratmatris foer biologiskt aktiva substanser, saett att framstaella densamma samt dess anvaendning.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8204244A SE8204244L (sv) 1982-07-09 1982-07-09 Kristalliserad kolhydratsmatris for biologiskt aktiva substanser

Publications (2)

Publication Number Publication Date
SE8204244D0 SE8204244D0 (sv) 1982-07-09
SE8204244L true SE8204244L (sv) 1984-01-10

Family

ID=20347337

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8204244A SE8204244L (sv) 1981-11-12 1982-07-09 Kristalliserad kolhydratsmatris for biologiskt aktiva substanser

Country Status (9)

Country Link
EP (1) EP0113749B1 (sv)
JP (1) JPS59501213A (sv)
AU (1) AU567434B2 (sv)
DE (1) DE3376797D1 (sv)
DK (1) DK95284A (sv)
FI (1) FI840923A (sv)
NO (1) NO840676L (sv)
SE (1) SE8204244L (sv)
WO (1) WO1984000294A1 (sv)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5720939A (en) * 1985-08-15 1998-02-24 Nycomed Imaging As Method of contrast enhanced magnetic resonance imaging using magnetically responsive-particles
US5618514A (en) * 1983-12-21 1997-04-08 Nycomed Imaging As Diagnostic and contrast agent
JPS60175539A (ja) * 1984-02-23 1985-09-09 Snow Brand Milk Prod Co Ltd カプセル体およびその製造法
US5266333A (en) * 1985-03-06 1993-11-30 American Cyanamid Company Water dispersible and water soluble carbohydrate polymer compositions for parenteral administration of growth hormone
US5075109A (en) * 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US5811128A (en) * 1986-10-24 1998-09-22 Southern Research Institute Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor
US5707604A (en) * 1986-11-18 1998-01-13 Access Pharmaceuticals, Inc. Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles
US5672334A (en) * 1991-01-16 1997-09-30 Access Pharmaceuticals, Inc. Invivo agents comprising cationic metal chelators with acidic saccharides and glycosaminoglycans
US4925678A (en) * 1987-04-01 1990-05-15 Ranney David F Endothelial envelopment drug carriers
US5108759A (en) * 1987-04-01 1992-04-28 Ranney David F Endothelial envelopment drug carriers
SE8701479L (sv) * 1987-04-09 1988-10-10 Carbomatrix Ab Metod foer inneslutning av biologiskt verksamma preparat samt anvaendning daerav
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
AU642066B2 (en) * 1991-01-25 1993-10-07 Nanosystems L.L.C. X-ray contrast compositions useful in medical imaging
US5399363A (en) * 1991-01-25 1995-03-21 Eastman Kodak Company Surface modified anticancer nanoparticles
US5874063A (en) * 1991-04-11 1999-02-23 Astra Aktiebolag Pharmaceutical formulation
SE9302777D0 (sv) * 1993-08-27 1993-08-27 Astra Ab Process for conditioning substances
JP3319754B2 (ja) * 1991-06-03 2002-09-03 ニユコメド・イメージング・アクシエセルカペト 造影剤におけるまたは造影剤に関する改良
GB9116610D0 (en) * 1991-08-01 1991-09-18 Danbiosyst Uk Preparation of microparticles
FR2692168B1 (fr) * 1992-06-16 1995-03-24 Centre Nat Rech Scient Préparation et utilisation de nouveaux systèmes colloïdaux dispersibles à base de cyclodextrine, sous forme de nanosphères.
MX9603936A (es) * 1994-03-07 1997-05-31 Inhale Therapeutic Syst Metodos y composiciones para el suministro pulmonar de insulina.
WO1996009805A2 (en) * 1994-09-23 1996-04-04 Zonagen, Inc. Chitosan induced immunopotentiation
US5912000A (en) * 1994-09-23 1999-06-15 Zonagen, Inc. Chitosan induced immunopotentiation
US6106866A (en) * 1995-07-31 2000-08-22 Access Pharmaceuticals, Inc. In vivo agents comprising cationic drugs, peptides and metal chelators with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles, including tumor sites
GB9526392D0 (en) 1995-12-22 1996-02-21 Glaxo Group Ltd Medicaments
IT1297461B1 (it) * 1997-10-29 1999-12-17 Ciocca Maurizio Preparazione di compresse a rilascio controllato a base di complessi tra carragenano e farmaci basici solubili
EP1184032A1 (en) * 2000-08-31 2002-03-06 OctoPlus B.V. Dextran hydrogels
EP1356826A1 (en) 2002-04-22 2003-10-29 BIOMAY Produktions- und Handels- Aktiengesellschaft Microparticles comprising carbohydrate beads covalently linked with allergen
WO2004078198A1 (en) * 2003-03-04 2004-09-16 The Technology Development Company Ltd. Long acting injectable insulin composition and methods of making and using thereof
EP1576952A1 (en) * 2004-03-18 2005-09-21 OctoPlus Technologies B.V. Hydrogel microspheres with improved release profile
SE0600091L (sv) 2006-01-18 2007-04-17 Bows Pharmaceuticals Ag Förfarande för framställning av en dextranmatris för kontrollerad frisättning av insulin

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52136911A (en) * 1976-05-06 1977-11-16 Eisai Co Ltd Solid ubidecarenone agent
JPS603998B2 (ja) * 1977-04-19 1985-01-31 凸版印刷株式会社 合成樹脂成形物への加熱転写法
JPS5547615A (en) * 1978-09-29 1980-04-04 Taiyo Yakuhin Kogyo Kk Stable solid drug of nifedipine
SE445013B (sv) * 1979-06-21 1986-05-26 Landstingens Inkopscentral Medel for att forebygga eller behandla infektioner hos menniskor och djur
DE2925009A1 (de) * 1979-06-21 1981-01-08 Basf Ag Zubereitung fuer substanzen, verfahren zu deren herstellung und deren verwendung
DE3147714A1 (de) * 1981-11-27 1983-06-01 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue prostacycline und verfahren zu ihrer herstellung
US5855764A (en) * 1997-07-15 1999-01-05 Exxon Research And Engineering Company Method for demetallating petroleum streams

Also Published As

Publication number Publication date
DE3376797D1 (en) 1988-07-07
JPS59501213A (ja) 1984-07-12
FI840923A0 (fi) 1984-03-07
AU567434B2 (en) 1987-11-19
EP0113749A1 (en) 1984-07-25
WO1984000294A1 (en) 1984-02-02
EP0113749B1 (en) 1988-06-01
DK95284D0 (da) 1984-02-23
AU1776083A (en) 1984-02-08
FI840923A (fi) 1984-03-07
DK95284A (da) 1984-02-23
NO840676L (no) 1984-02-22
SE8204244D0 (sv) 1982-07-09

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