SE8102131L - ERGOLINE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATION - Google Patents
ERGOLINE DERIVATIVES AND PROCEDURES FOR THEIR PREPARATIONInfo
- Publication number
- SE8102131L SE8102131L SE8102131A SE8102131A SE8102131L SE 8102131 L SE8102131 L SE 8102131L SE 8102131 A SE8102131 A SE 8102131A SE 8102131 A SE8102131 A SE 8102131A SE 8102131 L SE8102131 L SE 8102131L
- Authority
- SE
- Sweden
- Prior art keywords
- procedures
- preparation
- ergoline derivatives
- ergoline
- derivatives
- Prior art date
Links
- AWFDCTXCTHGORH-HGHGUNKESA-N 6-[4-[(6ar,9r,10ar)-5-bromo-7-methyl-6,6a,8,9,10,10a-hexahydro-4h-indolo[4,3-fg]quinoline-9-carbonyl]piperazin-1-yl]-1-methylpyridin-2-one Chemical class O=C([C@H]1CN([C@H]2[C@@H](C=3C=CC=C4NC(Br)=C(C=34)C2)C1)C)N(CC1)CCN1C1=CC=CC(=O)N1C AWFDCTXCTHGORH-HGHGUNKESA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 208000001953 Hypotension Diseases 0.000 abstract 1
- 150000001718 carbodiimides Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
FC-51+a Novel ergoline derivatives formed by reaction of an 8-carboxy ergoline with a carbodiimide having hypotensive and antiprolatinic activity.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8011234 | 1980-04-03 | ||
| GB8040575 | 1980-12-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8102131L true SE8102131L (en) | 1981-10-04 |
| SE442637B SE442637B (en) | 1986-01-20 |
Family
ID=26275073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8102131A SE442637B (en) | 1980-04-03 | 1981-04-02 | ERGOLINE DERIVATIVES, PROCEDURES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITION OF THEM |
Country Status (20)
| Country | Link |
|---|---|
| AT (1) | AT375076B (en) |
| AU (1) | AU540621B2 (en) |
| CA (1) | CA1156648A (en) |
| CH (1) | CH645896A5 (en) |
| CS (1) | CS415291A3 (en) |
| DE (1) | DE3112861A1 (en) |
| DK (1) | DK148686C (en) |
| ES (1) | ES500911A0 (en) |
| FI (1) | FI70412C (en) |
| FR (1) | FR2479829B1 (en) |
| GR (1) | GR74806B (en) |
| HK (1) | HK67287A (en) |
| IE (1) | IE51130B1 (en) |
| IL (1) | IL62519A (en) |
| IT (2) | IT1205241B (en) |
| NL (3) | NL189462C (en) |
| NZ (1) | NZ196670A (en) |
| PT (1) | PT72785B (en) |
| SE (1) | SE442637B (en) |
| YU (1) | YU43011B (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2173189B (en) * | 1985-02-21 | 1988-04-27 | Maruko Pharmaceutical Co | Ergoline derivatives and salts thereof and pharmaceutical compositions thereof |
| GB0409785D0 (en) | 2004-04-30 | 2004-06-09 | Resolution Chemicals Ltd | Preparation of cabergoline |
| GB0505965D0 (en) | 2005-03-23 | 2005-04-27 | Resolution Chemicals Ltd | Preparation of cabergoline |
| US7339060B2 (en) | 2005-03-23 | 2008-03-04 | Resolution Chemicals, Ltd. | Preparation of cabergoline |
| US7939665B2 (en) | 2007-05-04 | 2011-05-10 | Apotex Pharmachem Inc. | Efficient process for the preparation of cabergoline and its intermediates |
| EP2067780A1 (en) * | 2007-12-07 | 2009-06-10 | Axxonis Pharma AG | Ergoline derivatives as selective radical scavengers for neurons |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE396753B (en) * | 1970-05-18 | 1977-10-03 | Richter Gedeon Vegyeszet | ANALOGICAL PROCEDURE FOR PREPARING AN ASSOCIATION OF THE DIHYDROLYSERG ACID SERIES |
-
1981
- 1981-03-26 NL NLAANVRAGE8101509,A patent/NL189462C/en not_active IP Right Cessation
- 1981-03-30 IL IL62519A patent/IL62519A/en not_active IP Right Cessation
- 1981-03-30 AT AT0148481A patent/AT375076B/en not_active IP Right Cessation
- 1981-03-30 CA CA000374134A patent/CA1156648A/en not_active Expired
- 1981-03-30 CH CH214481A patent/CH645896A5/en not_active IP Right Cessation
- 1981-03-30 NZ NZ196670A patent/NZ196670A/en unknown
- 1981-03-31 DE DE19813112861 patent/DE3112861A1/en active Granted
- 1981-03-31 AU AU68937/81A patent/AU540621B2/en not_active Expired
- 1981-03-31 FR FR8106422A patent/FR2479829B1/en not_active Expired
- 1981-03-31 ES ES500911A patent/ES500911A0/en active Granted
- 1981-03-31 YU YU851/81A patent/YU43011B/en unknown
- 1981-04-01 IT IT20865/81A patent/IT1205241B/en active Protection Beyond IP Right Term
- 1981-04-01 IE IE754/81A patent/IE51130B1/en not_active IP Right Cessation
- 1981-04-01 IT IT8120866A patent/IT1210473B/en active
- 1981-04-01 GR GR64542A patent/GR74806B/el unknown
- 1981-04-01 PT PT72785A patent/PT72785B/en unknown
- 1981-04-02 SE SE8102131A patent/SE442637B/en not_active IP Right Cessation
- 1981-04-02 FI FI811025A patent/FI70412C/en not_active IP Right Cessation
- 1981-04-02 DK DK150781A patent/DK148686C/en not_active IP Right Cessation
-
1987
- 1987-09-17 HK HK672/87A patent/HK67287A/en not_active IP Right Cessation
-
1991
- 1991-12-30 CS CS914152A patent/CS415291A3/en unknown
-
1993
- 1993-06-24 NL NL930092C patent/NL930092I1/en unknown
- 1993-06-24 NL NL930091C patent/NL930091I2/en unknown
Also Published As
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Free format text: 9490132, 920313, EXPIRES: 20060402 |
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