SE8002521L - ANTIBACTERIAL ANTITUMOR AGENT - Google Patents
ANTIBACTERIAL ANTITUMOR AGENTInfo
- Publication number
- SE8002521L SE8002521L SE8002521A SE8002521A SE8002521L SE 8002521 L SE8002521 L SE 8002521L SE 8002521 A SE8002521 A SE 8002521A SE 8002521 A SE8002521 A SE 8002521A SE 8002521 L SE8002521 L SE 8002521L
- Authority
- SE
- Sweden
- Prior art keywords
- bbm
- complex
- against gram
- antitumor agent
- active
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
Abstract
An antitumor antibacterial complex having a quinoline nucleas referred to as BBM-928 is described which is produced by microbiological fermentation under controlled conditions using a species of actinomycetes. The bioactive components of the complex have pronounced antitumor activity and are moderately to weakly active against gram-positive and acid fast bacteria but practically inactive against gram- negative bacteria and fungi. Based on median survival time, the component designated BBM-928A is substantially more active than mitomycin C by a factor of 10 to 300 fold against intraperitoneally implanted mouse tumors.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2648879A | 1979-04-02 | 1979-04-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE8002521L true SE8002521L (en) | 1980-10-03 |
| SE441930B SE441930B (en) | 1985-11-18 |
Family
ID=21832125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8002521A SE441930B (en) | 1979-04-02 | 1980-04-01 | ANTIBIOTIC ANTITUMOR COMPLEX PRODUCED BY CULTIVATION OF ACTINOMYCETES (ATCC 31491) AND PROCEDURE FOR THEIR PRODUCTION |
Country Status (24)
| Country | Link |
|---|---|
| JP (3) | JPS55162752A (en) |
| AR (1) | AR223372A1 (en) |
| AT (1) | AT371144B (en) |
| AU (1) | AU533672B2 (en) |
| BE (1) | BE882574A (en) |
| CH (1) | CH647247A5 (en) |
| DE (1) | DE3012565A1 (en) |
| DK (1) | DK153501C (en) |
| ES (1) | ES8104411A1 (en) |
| FI (1) | FI67403C (en) |
| FR (1) | FR2452930A1 (en) |
| GB (1) | GB2050384B (en) |
| GR (1) | GR66663B (en) |
| HU (1) | HU184256B (en) |
| IE (1) | IE49191B1 (en) |
| IL (1) | IL59746A (en) |
| LU (1) | LU82318A1 (en) |
| NL (1) | NL8001868A (en) |
| NO (1) | NO155780C (en) |
| PH (1) | PH16970A (en) |
| SE (1) | SE441930B (en) |
| SU (1) | SU999981A3 (en) |
| YU (1) | YU41700B (en) |
| ZA (1) | ZA801856B (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4416874A (en) | 1982-03-05 | 1983-11-22 | Bristol-Myers Company | Injectable compositions of BBM-928A |
| AU566569B2 (en) * | 1983-01-31 | 1987-10-22 | Bristol-Myers Company | Luzopeptin e2 |
| ATE31623T1 (en) * | 1983-09-14 | 1988-01-15 | Bristol Myers Co | INJECTABLE COMPOSITIONS OF BBM-928A. |
| US6749993B2 (en) | 2002-02-06 | 2004-06-15 | Konica Corporation | Planographic printing precursor and printing method employing the same |
| JP2003300382A (en) | 2002-04-08 | 2003-10-21 | Konica Minolta Holdings Inc | Imaging method using heat-transfer intermediate transfer medium |
| JP2004188848A (en) | 2002-12-12 | 2004-07-08 | Konica Minolta Holdings Inc | Print plate material |
| JP2004322511A (en) | 2003-04-25 | 2004-11-18 | Konica Minolta Medical & Graphic Inc | Printing method |
| JP2006056184A (en) | 2004-08-23 | 2006-03-02 | Konica Minolta Medical & Graphic Inc | Printing plate material and printing plate |
| JPWO2007052470A1 (en) | 2005-11-01 | 2009-04-30 | コニカミノルタエムジー株式会社 | Lithographic printing plate material, lithographic printing plate, lithographic printing plate preparation method and lithographic printing plate printing method |
| JP4878612B2 (en) * | 2008-07-16 | 2012-02-15 | スタンレー電気株式会社 | Vehicle signal lights |
| US9052217B2 (en) | 2012-11-09 | 2015-06-09 | Honeywell International Inc. | Variable scale sensor |
-
1980
- 1980-03-19 GB GB8009192A patent/GB2050384B/en not_active Expired
- 1980-03-21 PH PH23791A patent/PH16970A/en unknown
- 1980-03-24 IE IE598/80A patent/IE49191B1/en not_active IP Right Cessation
- 1980-03-24 YU YU812/80A patent/YU41700B/en unknown
- 1980-03-26 GR GR58775A patent/GR66663B/el unknown
- 1980-03-28 FI FI800973A patent/FI67403C/en not_active IP Right Cessation
- 1980-03-28 ZA ZA00801856A patent/ZA801856B/en unknown
- 1980-03-28 NL NL8001868A patent/NL8001868A/en not_active Application Discontinuation
- 1980-03-31 FR FR8007145A patent/FR2452930A1/en active Granted
- 1980-03-31 DE DE19803012565 patent/DE3012565A1/en active Granted
- 1980-03-31 DK DK138780A patent/DK153501C/en not_active IP Right Cessation
- 1980-03-31 IL IL59746A patent/IL59746A/en unknown
- 1980-03-31 AU AU57002/80A patent/AU533672B2/en not_active Ceased
- 1980-04-01 ES ES490209A patent/ES8104411A1/en not_active Expired
- 1980-04-01 LU LU82318A patent/LU82318A1/en unknown
- 1980-04-01 SE SE8002521A patent/SE441930B/en not_active IP Right Cessation
- 1980-04-01 CH CH2570/80A patent/CH647247A5/en not_active IP Right Cessation
- 1980-04-01 BE BE0/200071A patent/BE882574A/en not_active IP Right Cessation
- 1980-04-01 HU HU80775A patent/HU184256B/en not_active IP Right Cessation
- 1980-04-01 NO NO800967A patent/NO155780C/en unknown
- 1980-04-01 SU SU802906901A patent/SU999981A3/en active
- 1980-04-02 AR AR280558A patent/AR223372A1/en active
- 1980-04-02 JP JP4205180A patent/JPS55162752A/en active Granted
- 1980-04-02 AT AT0180380A patent/AT371144B/en not_active IP Right Cessation
-
1987
- 1987-10-09 JP JP62253589A patent/JPS63139192A/en active Granted
- 1987-10-09 JP JP62253588A patent/JPS63139191A/en active Granted
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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