SE7714526L - METHODS OF PRODUCING 2-AMINO-CYCLOPENT-1-EN-1-THIOCARBONYL DISULFIDES - Google Patents
METHODS OF PRODUCING 2-AMINO-CYCLOPENT-1-EN-1-THIOCARBONYL DISULFIDESInfo
- Publication number
- SE7714526L SE7714526L SE7714526A SE7714526A SE7714526L SE 7714526 L SE7714526 L SE 7714526L SE 7714526 A SE7714526 A SE 7714526A SE 7714526 A SE7714526 A SE 7714526A SE 7714526 L SE7714526 L SE 7714526L
- Authority
- SE
- Sweden
- Prior art keywords
- carbon atoms
- amino
- cyclopent
- thiocarbonyl
- disulfides
- Prior art date
Links
- -1 2-AMINO-CYCLOPENT-1-EN-1-THIOCARBONYL DISULFIDES Chemical class 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 108010015720 Dopamine beta-Hydroxylase Proteins 0.000 abstract 1
- 102100033156 Dopamine beta-hydroxylase Human genes 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Novel N-substituted 2-amino-cyclopent-1-ene-1-dithiocarboxylic acids of the general formula <IMAGE> in which R denotes an unsubstituted straight or branched alkyl group having 5 or 6 carbon atoms, an alkyl group having 1 to 6 carbon atoms, which is substituted by alkoxy groups having 1 to 4 carbon atoms, or by hydroxyl, carboxyl and/or amino groups, an alkenyl group having 2 to 4 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, or a phenyl group, are prepared by reacting 2-amino-cyclopent-1-ene-1-dithiocarboxylic acid with amines of the general formula NH2-R. The novel compounds have a dopamine- beta -hydroxylase-inhibiting effect.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU76RI610A HU175526B (en) | 1976-12-30 | 1976-12-30 | Process for producing 2-amino-cyclopent-1-2n2-1-dithiocarboxylic acid -disulfides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE7714526L true SE7714526L (en) | 1978-07-01 |
Family
ID=11001014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7714526A SE7714526L (en) | 1976-12-30 | 1977-12-20 | METHODS OF PRODUCING 2-AMINO-CYCLOPENT-1-EN-1-THIOCARBONYL DISULFIDES |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS5384949A (en) |
| AR (1) | AR216308A1 (en) |
| AT (1) | AT351501B (en) |
| AU (1) | AU516353B2 (en) |
| BE (1) | BE862408A (en) |
| CH (1) | CH631701A5 (en) |
| DE (1) | DE2758809A1 (en) |
| ES (1) | ES465567A1 (en) |
| FI (1) | FI66595C (en) |
| FR (1) | FR2376132A1 (en) |
| GB (1) | GB1582716A (en) |
| HU (1) | HU175526B (en) |
| IL (1) | IL53646A (en) |
| IN (1) | IN146470B (en) |
| NL (1) | NL7714514A (en) |
| NO (1) | NO145237C (en) |
| PT (1) | PT67482B (en) |
| SE (1) | SE7714526L (en) |
| SU (1) | SU743580A3 (en) |
| YU (1) | YU309677A (en) |
| ZA (1) | ZA777573B (en) |
-
1976
- 1976-12-30 HU HU76RI610A patent/HU175526B/en unknown
-
1977
- 1977-12-19 IL IL53646A patent/IL53646A/en unknown
- 1977-12-20 AT AT912077A patent/AT351501B/en not_active IP Right Cessation
- 1977-12-20 ZA ZA00777573A patent/ZA777573B/en unknown
- 1977-12-20 SE SE7714526A patent/SE7714526L/en not_active Application Discontinuation
- 1977-12-21 CH CH1582477A patent/CH631701A5/en not_active IP Right Cessation
- 1977-12-23 AU AU31979/77A patent/AU516353B2/en not_active Expired
- 1977-12-26 FR FR7739183A patent/FR2376132A1/en active Granted
- 1977-12-27 YU YU03096/77A patent/YU309677A/en unknown
- 1977-12-27 IN IN1772/CAL/77A patent/IN146470B/en unknown
- 1977-12-28 SU SU772559902A patent/SU743580A3/en active
- 1977-12-28 BE BE183912A patent/BE862408A/en not_active IP Right Cessation
- 1977-12-29 FI FI773967A patent/FI66595C/en not_active IP Right Cessation
- 1977-12-29 NL NL7714514A patent/NL7714514A/en not_active Application Discontinuation
- 1977-12-29 ES ES465567A patent/ES465567A1/en not_active Expired
- 1977-12-29 PT PT67482A patent/PT67482B/en unknown
- 1977-12-29 JP JP15853077A patent/JPS5384949A/en active Pending
- 1977-12-29 NO NO774502A patent/NO145237C/en unknown
- 1977-12-29 GB GB54173/77A patent/GB1582716A/en not_active Expired
- 1977-12-29 AR AR270573A patent/AR216308A1/en active
- 1977-12-30 DE DE19772758809 patent/DE2758809A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| NL7714514A (en) | 1978-07-04 |
| PT67482B (en) | 1979-05-30 |
| SU743580A3 (en) | 1980-06-25 |
| CH631701A5 (en) | 1982-08-31 |
| FR2376132B1 (en) | 1979-10-19 |
| IL53646A0 (en) | 1978-03-10 |
| HU175526B (en) | 1980-08-28 |
| IN146470B (en) | 1979-06-09 |
| ATA912077A (en) | 1979-01-15 |
| AU516353B2 (en) | 1981-05-28 |
| YU309677A (en) | 1983-01-21 |
| AR216308A1 (en) | 1979-12-14 |
| GB1582716A (en) | 1981-01-14 |
| AT351501B (en) | 1979-07-25 |
| NO145237C (en) | 1982-02-10 |
| BE862408A (en) | 1978-04-14 |
| ZA777573B (en) | 1978-10-25 |
| FI66595B (en) | 1984-07-31 |
| AU3197977A (en) | 1979-06-28 |
| IL53646A (en) | 1982-03-31 |
| ES465567A1 (en) | 1979-01-01 |
| FR2376132A1 (en) | 1978-07-28 |
| NO145237B (en) | 1981-11-02 |
| PT67482A (en) | 1978-01-01 |
| DE2758809A1 (en) | 1978-07-06 |
| NO774502L (en) | 1978-07-03 |
| FI773967A (en) | 1978-07-01 |
| FI66595C (en) | 1984-11-12 |
| JPS5384949A (en) | 1978-07-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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