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SE7713440L - ALKANOYLANILIDE DERIVATIVES - Google Patents

ALKANOYLANILIDE DERIVATIVES

Info

Publication number
SE7713440L
SE7713440L SE7713440A SE7713440A SE7713440L SE 7713440 L SE7713440 L SE 7713440L SE 7713440 A SE7713440 A SE 7713440A SE 7713440 A SE7713440 A SE 7713440A SE 7713440 L SE7713440 L SE 7713440L
Authority
SE
Sweden
Prior art keywords
compounds
alkanoylanilide
derivatives
prepared
formula
Prior art date
Application number
SE7713440A
Other languages
Swedish (sv)
Other versions
SE442198B (en
Inventor
J Szmuszkovicz
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of SE7713440L publication Critical patent/SE7713440L/en
Publication of SE442198B publication Critical patent/SE442198B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/02—Dicarboxylic acids
    • C07C55/06—Oxalic acid
    • C07C55/07—Salts thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/145—Maleic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/15—Fumaric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel N-(aminocycloheptyl)-N-alkanoyl anilides of the formula <IMAGE> in which the substituents are described in Claim 1, are prepared. These compounds are obtained by acylating an appropriately substituted N-[2-(disubstituted amino)-cycloheptyl]aniline with an acid anhydride or an acid halide. The corresponding N-oxides are prepared from compounds of the formula I by oxidation with a percarbonic acid. The compounds which are obtained can be used as antidepressants.
SE7713440A 1977-03-21 1977-11-28 PROCEDURE FOR PREPARING NEW N- (2-AMINOCYCLOHEPTYL) -N-ALKANOYLANILIDES SE442198B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US77959377A 1977-03-21 1977-03-21

Publications (2)

Publication Number Publication Date
SE7713440L true SE7713440L (en) 1978-09-22
SE442198B SE442198B (en) 1985-12-09

Family

ID=25116918

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7713440A SE442198B (en) 1977-03-21 1977-11-28 PROCEDURE FOR PREPARING NEW N- (2-AMINOCYCLOHEPTYL) -N-ALKANOYLANILIDES
SE8204694A SE8204694L (en) 1977-03-21 1982-08-13 ALKANOYLANILINDERIVAT
SE8204695A SE8204695L (en) 1977-03-21 1982-08-13 ALKANOYLANILINDERIVAT

Family Applications After (2)

Application Number Title Priority Date Filing Date
SE8204694A SE8204694L (en) 1977-03-21 1982-08-13 ALKANOYLANILINDERIVAT
SE8204695A SE8204695L (en) 1977-03-21 1982-08-13 ALKANOYLANILINDERIVAT

Country Status (9)

Country Link
JP (1) JPS53116347A (en)
AU (1) AU511540B2 (en)
BE (1) BE861352A (en)
CH (4) CH636341A5 (en)
DE (1) DE2749213A1 (en)
FR (1) FR2384744A1 (en)
GB (2) GB1557595A (en)
NL (1) NL7712898A (en)
SE (3) SE442198B (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3510492A (en) * 1968-05-13 1970-05-05 Upjohn Co 2-anilino and 2-anilinomethyl cycloalkylamines

Also Published As

Publication number Publication date
SE8204695D0 (en) 1982-08-13
SE8204694D0 (en) 1982-08-13
AU3049077A (en) 1979-05-17
GB1557594A (en) 1979-12-12
AU511540B2 (en) 1980-08-21
CH636341A5 (en) 1983-05-31
CH636597A5 (en) 1983-06-15
DE2749213A1 (en) 1978-10-05
FR2384744A1 (en) 1978-10-20
GB1557595A (en) 1979-12-12
JPS53116347A (en) 1978-10-11
BE861352A (en) 1978-05-30
NL7712898A (en) 1978-09-25
SE8204695L (en) 1982-08-13
SE8204694L (en) 1982-08-13
CH636604A5 (en) 1983-06-15
SE442198B (en) 1985-12-09
FR2384744B1 (en) 1980-08-22
JPS6146471B2 (en) 1986-10-14
CH637110A5 (en) 1983-07-15
DE2749213C2 (en) 1988-09-08

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