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SE7705848L - NEW ISOKINOLINE DERIVATIVE - Google Patents

NEW ISOKINOLINE DERIVATIVE

Info

Publication number
SE7705848L
SE7705848L SE7705848A SE7705848A SE7705848L SE 7705848 L SE7705848 L SE 7705848L SE 7705848 A SE7705848 A SE 7705848A SE 7705848 A SE7705848 A SE 7705848A SE 7705848 L SE7705848 L SE 7705848L
Authority
SE
Sweden
Prior art keywords
isoquinoline
isokinoline
derivative
new
isoquinol
Prior art date
Application number
SE7705848A
Other languages
Swedish (sv)
Inventor
D Farge
A Jossin
G Ponsinet
D Reisdorf
Original Assignee
Rhone Poulenc Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Ind filed Critical Rhone Poulenc Ind
Publication of SE7705848L publication Critical patent/SE7705848L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1530077 5 - Isothiocyanato - isoquinoline and uses thereof RHONE-POULENC INDUSTRIES 16 May 1977 [18 May 1976] 20557/77 Heading C2C The novel compound 5-isothiocyanato-isoquinoline is prepared by reacting 5-amino-isoquinoline with carbon disulphide and then N,N<SP>1</SP>-dicyclohexylcarbodiimide. The novel compound may be reacted with a 3 - hydroxmethyl - 1,2,3,4 - tetrahydroisoquinoline to form a 3-hydroxymethyl-N-(isoquinol - 5 - yl) - 1,2,3,4 - tetrahydroisoquinoline-2- carbothioamide, which in turn may be cyclized to a 3-(isoquinol-5-ylimino)-1,5,10,10a-tetrahydrothiazolo[3,4-6]-isoquinoline, which as the free base or an acid addition salt shows analgesic and antipyretic activity.
SE7705848A 1976-05-18 1977-05-17 NEW ISOKINOLINE DERIVATIVE SE7705848L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7614936A FR2351966A1 (en) 1976-05-18 1976-05-18 NEW DERIVATIVE OF ISOQUINOLEINE

Publications (1)

Publication Number Publication Date
SE7705848L true SE7705848L (en) 1977-11-19

Family

ID=9173278

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7705848A SE7705848L (en) 1976-05-18 1977-05-17 NEW ISOKINOLINE DERIVATIVE

Country Status (7)

Country Link
BE (1) BE854761A (en)
DE (1) DE2722637A1 (en)
DK (1) DK214477A (en)
FR (1) FR2351966A1 (en)
GB (1) GB1530077A (en)
NL (1) NL7705151A (en)
SE (1) SE7705848L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3830119A1 (en) * 1988-09-05 1990-03-15 Standard Elektrik Lorenz Ag Optical coupling device

Also Published As

Publication number Publication date
NL7705151A (en) 1977-11-22
BE854761A (en) 1977-11-17
DE2722637A1 (en) 1977-12-08
FR2351966A1 (en) 1977-12-16
GB1530077A (en) 1978-10-25
DK214477A (en) 1977-11-19

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Legal Events

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NAV Patent application has lapsed

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Effective date: 19790928