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SE455836B - Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning - Google Patents

Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning

Info

Publication number
SE455836B
SE455836B SE8504721A SE8504721A SE455836B SE 455836 B SE455836 B SE 455836B SE 8504721 A SE8504721 A SE 8504721A SE 8504721 A SE8504721 A SE 8504721A SE 455836 B SE455836 B SE 455836B
Authority
SE
Sweden
Prior art keywords
metoprolol
preparation according
salt
grains
size
Prior art date
Application number
SE8504721A
Other languages
English (en)
Swedish (sv)
Other versions
SE8504721L (sv
SE8504721D0 (sv
Inventor
U E Jonsson
J A Sandberg
J A Sjogren
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20361706&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE455836(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Haessle Ab filed Critical Haessle Ab
Priority to SE8504721A priority Critical patent/SE455836B/sv
Publication of SE8504721D0 publication Critical patent/SE8504721D0/xx
Priority to ZA869860A priority patent/ZA869860B/xx
Priority to IE249286A priority patent/IE59053B1/en
Priority to PH34289A priority patent/PH22277A/en
Priority to GB8623048A priority patent/GB2181348B/en
Priority to AU63171/86A priority patent/AU588630B2/en
Priority to NZ217696A priority patent/NZ217696A/xx
Priority to ES86850330T priority patent/ES2003863B3/es
Priority to AT86850330T priority patent/ATE65391T1/de
Priority to DE198686850330T priority patent/DE220143T1/de
Priority to EP86850330A priority patent/EP0220143B1/en
Priority to DE8686850330T priority patent/DE3680450D1/de
Priority to NO863997A priority patent/NO172276C/no
Priority to DK478186A priority patent/DK165939C/da
Priority to DZ860208A priority patent/DZ994A1/fr
Priority to PT83509A priority patent/PT83509B/pt
Priority to JP61239424A priority patent/JPH0759506B2/ja
Priority to SU864028342A priority patent/SU1760969A3/ru
Priority to HU864249A priority patent/HU197839B/hu
Priority to FI864108A priority patent/FI88579C/fi
Priority to KR1019860008481A priority patent/KR940000100B1/ko
Priority to IS3151A priority patent/IS1529B/is
Priority to PL1986261802A priority patent/PL261802A1/xx
Priority to CA000520266A priority patent/CA1293449C/en
Priority to DD86295170A priority patent/DD259789A5/de
Priority to UA4028342A priority patent/UA26211A/uk
Priority to CN86106588A priority patent/CN1023293C/zh
Publication of SE8504721L publication Critical patent/SE8504721L/
Publication of SE455836B publication Critical patent/SE455836B/sv
Priority to US07/310,489 priority patent/US4957745A/en
Priority to GR89300059T priority patent/GR890300059T1/el
Priority to GR91401214T priority patent/GR3002571T3/el
Priority to SU915001493A priority patent/RU2072840C1/ru
Priority to UA5001493A priority patent/UA39162C2/uk
Priority to SG952/91A priority patent/SG95291G/en
Priority to HK1017/91A priority patent/HK101791A/xx
Priority to CY1616A priority patent/CY1616A/en
Priority to LVP-93-685A priority patent/LV10913B/en
Priority to LV930884A priority patent/LV10914A/lv
Priority to LTIP1679A priority patent/LT3951B/lt
Priority to LTIP1680A priority patent/LTIP1680A/xx
Priority to LV960258A priority patent/LV5751B4/lv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SE8504721A 1985-10-11 1985-10-11 Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning SE455836B (sv)

Priority Applications (40)

Application Number Priority Date Filing Date Title
SE8504721A SE455836B (sv) 1985-10-11 1985-10-11 Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning
ZA869860A ZA869860B (en) 1985-10-11 1986-09-09 New pharmaceutical preparation
IE249286A IE59053B1 (en) 1985-10-11 1986-09-18 Controlled release metoprolol preparations
PH34289A PH22277A (en) 1985-10-11 1986-09-25 Controlled release preparation containing salt of metoprolol and method of use thereof
GB8623048A GB2181348B (en) 1985-10-11 1986-09-25 Controlled release metoprolol preparations
AU63171/86A AU588630B2 (en) 1985-10-11 1986-09-26 Pharmaceutical preparation with controlled release of metoprolol
NZ217696A NZ217696A (en) 1985-10-11 1986-09-26 Sustained release compositions containing 'metroprolol'
DE8686850330T DE3680450D1 (de) 1985-10-11 1986-10-02 Pharmazeutische zubereitungen von metoprolol mit kontrollierter wirkstoffabgabe, verfahren zu ihrer herstellung und verwendung dieser zubereitungen.
EP86850330A EP0220143B1 (en) 1985-10-11 1986-10-02 New pharmaceutical preparation with controlled release of metoprolol, a method for the manufacture thereof and the use of the new preparation
ES86850330T ES2003863B3 (es) 1985-10-11 1986-10-02 Nueva preparacion farmaceutica con liberacion controlada de metoprolol, metodo para su fabricacion y uso de la nueva preparacion.
AT86850330T ATE65391T1 (de) 1985-10-11 1986-10-02 Pharmazeutische zubereitungen von metoprolol mit kontrollierter wirkstoffabgabe, verfahren zu ihrer herstellung und verwendung dieser zubereitungen.
DE198686850330T DE220143T1 (de) 1985-10-11 1986-10-02 Pharmazeutische zubereitungen von metoprolol mit kontrollierter wirkstoff abgabe, verfahren zu ihrer herstellung und verwendung dieser zubereitungen.
NO863997A NO172276C (no) 1985-10-11 1986-10-07 Fremgangsmaate for fremstilling av et farmasoeytisk preparat med regulert frigjoering
DK478186A DK165939C (da) 1985-10-11 1986-10-07 Metropololpraeparat med styret, kontinuerlig afgivelse af det aktive stof, farmaceutisk praeparat indeholdende samme og fremgangsmaade til fremstilling af metropololpraeparatet samt anvendelse af metropololpraeparatet til fremstilling af et farmaceutisk praeparat til behandling af kardiovaskulaere lidelser
DZ860208A DZ994A1 (fr) 1985-10-11 1986-10-08 Nouvelle préparation pharmaceutique.
PT83509A PT83509B (pt) 1985-10-11 1986-10-09 Processo para a preparacao de composicoes farmaceuticas de accao prolongada que contem um sal de metoprolol
JP61239424A JPH0759506B2 (ja) 1985-10-11 1986-10-09 医薬製剤
DD86295170A DD259789A5 (de) 1985-10-11 1986-10-10 Pharmazeutisches praeparat und verfahren zu dessen herstellung
UA4028342A UA26211A (uk) 1985-10-11 1986-10-10 Спосіб одержаhhя твердої лікарської форми метопролола з регульоваhим його вивільhеhhям
FI864108A FI88579C (fi) 1985-10-11 1986-10-10 Foerfarande foer framstaellning av en beredning med kontrollerad foersaettning av metoprolol
HU864249A HU197839B (en) 1985-10-11 1986-10-10 Process for producing metoprolol containing pharmaceutical compositions
SU864028342A SU1760969A3 (ru) 1985-10-11 1986-10-10 Способ получени твердой лекарственной формы метопролола с регулируемым его высвобождением
KR1019860008481A KR940000100B1 (ko) 1985-10-11 1986-10-10 메토프롤롤염을 함유하는 서방형 제제의 제조방법
IS3151A IS1529B (is) 1985-10-11 1986-10-10 Aðferð við framleiðslu á nýrri lyfjablöndu með tempraðri losun á metaprolol
PL1986261802A PL261802A1 (en) 1985-10-11 1986-10-10 Method of obtaining a controllably released preparation containing methoprolole salt
CA000520266A CA1293449C (en) 1985-10-11 1986-10-10 Controlled release drug preparation
CN86106588A CN1023293C (zh) 1985-10-11 1986-10-11 一种含有美多心安盐的控制释放制剂的制备方法
US07/310,489 US4957745A (en) 1985-10-11 1989-02-14 Pharmaceutical preparation
GR89300059T GR890300059T1 (en) 1985-10-11 1989-06-22 New pharmaceutical preparation with controlled release of metoprolol, a method for the manufacture thereof and the use of the new preparation
GR91401214T GR3002571T3 (en) 1985-10-11 1991-08-19 New pharmaceutical preparation with controlled release of metoprolol, a method for the manufacture thereof and the use of the new preparation
SU915001493A RU2072840C1 (ru) 1985-10-11 1991-09-10 Твердая лекарственная форма пролонгированного действия для лечения сердечно-сосудистых заболеваний
UA5001493A UA39162C2 (uk) 1985-10-11 1991-09-10 Тверда лікарська форма з регульованим вивільненням активного початку
SG952/91A SG95291G (en) 1985-10-11 1991-11-08 Controlled release metoprolol preparations
HK1017/91A HK101791A (en) 1985-10-11 1991-12-12 Controlled release metoprolol preparations
CY1616A CY1616A (en) 1985-10-11 1992-07-10 Controlled release metoprolol preparations
LVP-93-685A LV10913B (en) 1985-10-11 1993-06-28 New pharmaceutical praparation, a method of producing said preparation and its use
LV930884A LV10914A (lv) 1985-10-11 1993-06-30 Panemiens jauna arstniecibas lidzekla iegusanai
LTIP1679A LT3951B (en) 1985-10-11 1993-12-28 Pharmaceutical preparation
LTIP1680A LTIP1680A (en) 1985-10-11 1993-12-28 Pharmaceutical preparation
LV960258A LV5751B4 (lv) 1985-10-11 1996-07-17 Farmaceitisks preparats

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8504721A SE455836B (sv) 1985-10-11 1985-10-11 Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning

Publications (3)

Publication Number Publication Date
SE8504721D0 SE8504721D0 (sv) 1985-10-11
SE8504721L SE8504721L (sv) 1987-04-12
SE455836B true SE455836B (sv) 1988-08-15

Family

ID=20361706

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8504721A SE455836B (sv) 1985-10-11 1985-10-11 Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning

Country Status (33)

Country Link
US (1) US4957745A (lv)
EP (1) EP0220143B1 (lv)
JP (1) JPH0759506B2 (lv)
KR (1) KR940000100B1 (lv)
CN (1) CN1023293C (lv)
AT (1) ATE65391T1 (lv)
AU (1) AU588630B2 (lv)
CY (1) CY1616A (lv)
DD (1) DD259789A5 (lv)
DE (2) DE3680450D1 (lv)
DK (1) DK165939C (lv)
DZ (1) DZ994A1 (lv)
ES (1) ES2003863B3 (lv)
FI (1) FI88579C (lv)
GB (1) GB2181348B (lv)
GR (2) GR890300059T1 (lv)
HK (1) HK101791A (lv)
HU (1) HU197839B (lv)
IE (1) IE59053B1 (lv)
IS (1) IS1529B (lv)
LT (2) LTIP1680A (lv)
LV (3) LV10913B (lv)
NO (1) NO172276C (lv)
NZ (1) NZ217696A (lv)
PH (1) PH22277A (lv)
PL (1) PL261802A1 (lv)
PT (1) PT83509B (lv)
RU (1) RU2072840C1 (lv)
SE (1) SE455836B (lv)
SG (1) SG95291G (lv)
SU (1) SU1760969A3 (lv)
UA (2) UA26211A (lv)
ZA (1) ZA869860B (lv)

Families Citing this family (61)

* Cited by examiner, † Cited by third party
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SE8703881D0 (sv) * 1987-10-08 1987-10-08 Haessle Ab New pharmaceutical preparation
US4892739A (en) * 1988-04-25 1990-01-09 Ciba-Geigy Corporation Osmotic continuous dispensing oral delivery system containing a pharmaceutically acceptable active agent having a improved core membrane adhesion properties
US5268182A (en) * 1988-06-24 1993-12-07 Abbott Laboratories Sustained-release drug dosage units of terazosin
US5612059A (en) * 1988-08-30 1997-03-18 Pfizer Inc. Use of asymmetric membranes in delivery devices
US5084287A (en) * 1990-03-15 1992-01-28 Warner-Lambert Company Pharmaceutically useful micropellets with a drug-coated core and controlled-release polymeric coat
CA2087435C (en) * 1990-08-07 1998-05-05 Scott Max Herbig Use of interfacially-polymerized membranes in delivery devices
EP0677291A3 (en) * 1991-03-18 1996-08-07 Sepracor Inc Composition and method containing optically pure S-metoprolol.
WO1992020326A1 (en) * 1991-05-20 1992-11-26 Marion Laboratories, Inc. Multi-layered controlled release formulation
IT1252185B (it) * 1991-12-11 1995-06-05 Therapicon Srl Preparazioni farmaceutiche a liberazione programmata
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
US5399358A (en) * 1993-11-12 1995-03-21 Edward Mendell Co., Inc. Sustained release formulations for 24 hour release of metroprolol
US8071128B2 (en) 1996-06-14 2011-12-06 Kyowa Hakko Kirin Co., Ltd. Intrabuccally rapidly disintegrating tablet and a production method of the tablets
SE9702338D0 (sv) * 1997-06-18 1997-06-18 Astra Ab An analytical method and industrial process including the same
SE9802537D0 (sv) * 1998-07-13 1998-07-13 Astra Ab Method for controlling a coating process
US8293277B2 (en) 1998-10-01 2012-10-23 Alkermes Pharma Ireland Limited Controlled-release nanoparticulate compositions
US8236352B2 (en) 1998-10-01 2012-08-07 Alkermes Pharma Ireland Limited Glipizide compositions
EP2266542A3 (en) * 1998-10-01 2013-07-31 Elan Pharma International Limited Controlled release nanoparticulate compositions
DE19848651C1 (de) * 1998-10-22 2000-01-27 Porsche Ag Tülle für ein Kabelbündel
EP1146862B1 (de) * 1999-01-29 2003-04-23 Disphar International B.V. Pharmazeutische zusammensetzungen
FR2802424B1 (fr) * 1999-12-17 2002-02-15 Adir Comprime matriciel permettant la liberation prolongee de trimetazidine apres administration par voie orale
US7198795B2 (en) 2000-09-21 2007-04-03 Elan Pharma International Ltd. In vitro methods for evaluating the in vivo effectiveness of dosage forms of microparticulate of nanoparticulate active agent compositions
GB0025208D0 (en) 2000-10-13 2000-11-29 Euro Celtique Sa Delayed release pharmaceutical formulations
SE0100200D0 (sv) * 2001-01-24 2001-01-24 Astrazeneca Ab New film coating
US6610326B2 (en) * 2001-02-16 2003-08-26 Andrx Corporation Divalproex sodium tablets
US20040105886A1 (en) * 2001-02-16 2004-06-03 Chih-Ming Chen Divalproex sodium tablets
SE0100824D0 (sv) * 2001-03-09 2001-03-09 Astrazeneca Ab Method III to obtain microparticles
US9358214B2 (en) 2001-10-04 2016-06-07 Adare Pharmaceuticals, Inc. Timed, sustained release systems for propranolol
ATE287259T1 (de) * 2001-12-19 2005-02-15 Astrazeneca Ab Neue filmbeschichtung enthaltend ein äthylacrylate/methylmethacrylate-copolymer und polyvinylacetat
EP1471887B1 (en) 2002-02-04 2010-04-21 Elan Pharma International Ltd. Nanoparticulate compositions having lysozyme as a surface stabilizer
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US8367111B2 (en) 2002-12-31 2013-02-05 Aptalis Pharmatech, Inc. Extended release dosage forms of propranolol hydrochloride
US7217300B2 (en) 2003-06-27 2007-05-15 Delphi Technologies, Inc. Method and apparatus for gasketing a fuel cell
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RU2072840C1 (ru) 1997-02-10
GB8623048D0 (en) 1986-10-29
DK165939B (da) 1993-02-15
DZ994A1 (fr) 2004-09-13
UA39162C2 (uk) 2001-06-15
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IS3151A7 (is) 1987-04-12
NO172276C (no) 1993-06-30
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DK165939C (da) 1993-07-05
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IE862492L (en) 1987-04-11
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PH22277A (en) 1988-07-14
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LV10914A (lv) 1995-12-20
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US4957745A (en) 1990-09-18
PT83509A (en) 1986-11-01
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CY1616A (en) 1992-07-10
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