[go: up one dir, main page]

SE410850B - Forfarande for framstellning av d,l-tyrosinderivat med farmacentisk aktivitet pa glatt muskulatur - Google Patents

Forfarande for framstellning av d,l-tyrosinderivat med farmacentisk aktivitet pa glatt muskulatur

Info

Publication number
SE410850B
SE410850B SE7501114A SE7501114A SE410850B SE 410850 B SE410850 B SE 410850B SE 7501114 A SE7501114 A SE 7501114A SE 7501114 A SE7501114 A SE 7501114A SE 410850 B SE410850 B SE 410850B
Authority
SE
Sweden
Prior art keywords
pharmacentic
tyrosin
derivatives
activity
procedure
Prior art date
Application number
SE7501114A
Other languages
English (en)
Swedish (sv)
Other versions
SE7501114L (sv
Inventor
F Makovec
L Rovati
P Senin
Original Assignee
Rotta Research Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rotta Research Lab filed Critical Rotta Research Lab
Publication of SE7501114L publication Critical patent/SE7501114L/xx
Publication of SE410850B publication Critical patent/SE410850B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE7501114A 1974-02-01 1975-01-31 Forfarande for framstellning av d,l-tyrosinderivat med farmacentisk aktivitet pa glatt muskulatur SE410850B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT67286/74A IT1062206B (it) 1974-02-01 1974-02-01 Derivati della tirosina attivi sulla muscolatura liscia

Publications (2)

Publication Number Publication Date
SE7501114L SE7501114L (sv) 1975-08-04
SE410850B true SE410850B (sv) 1979-11-12

Family

ID=11301149

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7501114A SE410850B (sv) 1974-02-01 1975-01-31 Forfarande for framstellning av d,l-tyrosinderivat med farmacentisk aktivitet pa glatt muskulatur
SE7501115A SE413094B (sv) 1974-02-01 1975-01-31 Analogiforfarande for framstellning av tyrosinderivat med farmaceutisk aktivitet pa glatt muskulatur

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE7501115A SE413094B (sv) 1974-02-01 1975-01-31 Analogiforfarande for framstellning av tyrosinderivat med farmaceutisk aktivitet pa glatt muskulatur

Country Status (19)

Country Link
US (1) US4004008A (nl)
JP (2) JPS5417728B2 (nl)
AT (2) AT343632B (nl)
BE (1) BE824995A (nl)
CA (2) CA1048503A (nl)
CH (2) CH605657A5 (nl)
DE (1) DE2503992C2 (nl)
ES (1) ES434323A1 (nl)
FI (2) FI63744C (nl)
FR (1) FR2259592B1 (nl)
GB (1) GB1467927A (nl)
HK (1) HK38979A (nl)
HU (2) HU174825B (nl)
IN (1) IN139364B (nl)
IT (1) IT1062206B (nl)
NL (1) NL167683C (nl)
NO (2) NO144211C (nl)
SE (2) SE410850B (nl)
ZA (1) ZA75530B (nl)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5225243A (en) * 1975-08-20 1977-02-25 Toshiba Electric Equip Corp Distributing panel
US4579866A (en) * 1984-05-29 1986-04-01 Usv Pharmaceutical Corp. Phenylacetamides as anti-allergy, anti-asthma and anti-inflammatory agents
CA1320734C (en) * 1986-02-04 1993-07-27 Suntory Limited Pyrrolidineamide derivative of acylamino acid and pharmaceutical composition containing the same
US5198458A (en) * 1986-02-04 1993-03-30 Suntory Limited Pyrrolidineamide derivatives of acylamino acid and pharmaceutical composition containing the same
IL99537A (en) * 1990-09-27 1995-11-27 Merck & Co Inc Fibrinogen receptor antagonists and pharmaceutical preparations containing them
NZ239846A (en) * 1990-09-27 1994-11-25 Merck & Co Inc Sulphonamide derivatives and pharmaceutical compositions thereof
US5258407A (en) * 1991-12-31 1993-11-02 Sterling Winthrop Inc. 3,4-disubstituted phenols-immunomodulating agents
US5206373A (en) * 1992-02-28 1993-04-27 Merck & Co., Inc. Process for preparing fibrinogen receptor antagonists
DE10204951A1 (de) * 2002-02-06 2003-08-14 Basf Ag Phenylalaninderivate als Herbizide
WO2005061443A2 (de) * 2003-12-19 2005-07-07 Basf Aktiengesellschaft Benzoylsubstituierte phenylalanin-amide
CN101267813A (zh) 2005-07-19 2008-09-17 第一三共株式会社 取代丙酰胺衍生物和含有其的药物组合物
WO2011094890A1 (en) * 2010-02-02 2011-08-11 Argusina Inc. Phenylalanine derivatives and their use as non-peptide glp-1 receptor modulators
EP2579888A2 (en) * 2010-06-09 2013-04-17 Receptos, Inc. Novel glp-1 receptor stabilizers and modulators
DK2713722T3 (en) 2011-05-31 2017-07-03 Celgene Int Ii Sarl Newly known GLP-1 receptor stabilizers and modulators
WO2013090454A2 (en) 2011-12-12 2013-06-20 Receptos, Inc. Novel glp-1 receptor modulators
CN102659619A (zh) * 2012-04-18 2012-09-12 上海骏捷生化科技有限公司 一种合成酪氨酸衍生物的方法
CN103508920B (zh) * 2012-06-21 2016-03-02 贵州百灵企业集团制药股份有限公司 一种苯丙氨醇化合物的光学异构体的制备方法及其用途
CN103508921B (zh) * 2012-06-21 2015-09-30 贵州百灵企业集团制药股份有限公司 一种苯丙氨醇化合物的制备方法
JP6573604B2 (ja) 2013-06-11 2019-09-11 セルジーン インターナショナル ツー エスエーアールエル 新規なｇｌｐ−１レセプターモジュレーター
ES2819534T3 (es) 2014-07-25 2021-04-16 Receptos Llc Derivados de pirimidina como moduladores del receptor GLP-1
US9795613B2 (en) 2014-12-10 2017-10-24 Celgene International Ii Sàrl GLP-1 receptor modulators
CN107417560B (zh) * 2017-03-30 2020-05-22 上海常丰生物医药科技有限公司 一种合成盐酸替罗酰胺的方法
CN110015978B (zh) * 2019-04-29 2021-03-19 康化（上海）新药研发有限公司 O-[2-[[叔丁氧羰基]氨基]乙基]-n-[芴甲氧羰基]-l-酪氨酸的合成方法
CN115850107B (zh) * 2022-11-30 2024-11-12 苏州诚和医药化学有限公司 一种工业化合成盐酸替罗酰胺的方法

Also Published As

Publication number Publication date
NO144211C (no) 1981-07-15
FR2259592B1 (nl) 1978-07-21
CA1048503A (en) 1979-02-13
FI63744C (fi) 1983-08-10
NO144210B (no) 1981-04-06
NO144211B (no) 1981-04-06
NL7501193A (nl) 1975-08-05
JPS50116441A (nl) 1975-09-11
SE7501114L (sv) 1975-08-04
FI63744B (fi) 1983-04-29
FI750255A (nl) 1975-08-02
DE2503992C2 (de) 1982-01-21
SE7501115L (sv) 1975-08-04
AT343632B (de) 1978-06-12
BE824995A (fr) 1975-05-15
FI61479B (fi) 1982-04-30
ZA75530B (en) 1976-01-28
ES434323A1 (es) 1976-12-16
CH605657A5 (nl) 1978-10-13
SE413094B (sv) 1980-04-14
AU7775075A (en) 1976-08-05
IT1062206B (it) 1983-09-20
FI750256A (nl) 1975-08-02
HU174825B (hu) 1980-03-28
FI61479C (fi) 1982-08-10
CA1047498A (en) 1979-01-30
US4004008A (en) 1977-01-18
JPS5417728B2 (nl) 1979-07-02
NO144210C (no) 1981-07-15
FR2259592A1 (nl) 1975-08-29
NO750288L (nl) 1975-08-25
GB1467927A (en) 1977-03-23
NO750287L (nl) 1975-08-25
AT342026B (de) 1978-03-10
NL167683C (nl) 1982-01-18
CH605658A5 (nl) 1978-10-13
DE2503992A1 (de) 1975-08-14
NL167683B (nl) 1981-08-17
JPS50116442A (nl) 1975-09-11
ATA74575A (de) 1977-07-15
HK38979A (en) 1979-06-22
ATA74675A (de) 1977-10-15
IN139364B (nl) 1976-06-12
JPS5417729B2 (nl) 1979-07-02
HU175156B (hu) 1980-05-28

Similar Documents

Publication Publication Date Title
SE410850B (sv) Forfarande for framstellning av d,l-tyrosinderivat med farmacentisk aktivitet pa glatt muskulatur
NO143218C (no) Analogifremgangsmaate til fremstilling av nonapeptidamider med lh-rh aktivitet
SE415761B (sv) Forfarande for framstellning av hexahydro-dibenso(b,d)pyran-9-on-derivat med terapeutisk verkan
SE417965B (sv) Forfarande for framstellning av 1-t-alkyl-3-(substituerad-tienyl respektive -tietyl)-karbamid-s,s-dioxid-derivat med antihypertensiv aktivitet
SE429336B (sv) Forfarande for framstellning av salicylanilidderivat med parasiticidaktivitet
NO140849C (no) Fremgangsmaate for fremstilling av lavfettholdige, smoerbare naeringsmidler av vann-i-olje-typen
SE423544B (sv) Analogiforfarande for framstellning av imidazolderivat med antifungisk aktivitet
SE7604475L (sv) Forfarande for framstellning av 1,1,1-triaryl-alkylaminer
TR18438A (tr) 1-etil-triazoller,bunlarin hazirlanmasina mahsus usul ve bunlarin fungisidler olarak kullanilmalari
SE419983B (sv) Forfarande for framstellning av finkornig, fast cyanurklorid
SE7505736L (sv) Polylaurinlactam, forfarande for framstellning av hogre polylactamer och deras anvendning
NL7504171A (nl) Tetracyclinederivaten en hun bereiding.
NL7506362A (nl) Gentamicinederivaten, alsmede hun bereidingswijze en geneeskundige toepassingen.
SE399557B (sv) Forfarande for framstellning av tiantren-, tioxanten- och fenoxatiinderivat
SE428922B (sv) Forfarande for framstellning av 13, 14-dihydro-11-dioxi-prostaglandiner
NO140104C (no) Analogifremgangsmaate til fremstilling av 17beta-hydroksy-16,16-dimetylestr-4-en-3-on med terapeutisk aktivitet
NL7513446A (nl) Nieuwe chinoxaline-1,4-dioxyde derivaten en werk- wijze voor hun bereiding.
NO147108C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme 1-amino-lavere-alkyl-3,4-difenyl-1h-pyrazoler
SE7600847L (sv) Nytt forfarande for framstellning av 8-bromtienotriazolo-1,4-diazepiner
BE838802A (fr) Derives de 3-amino-4-carbamyl-pyrrole, leur preparation et leur utilisation
BE839035A (fr) Derives de triazolobenzocycloalkylthiadiazine, leur preparation et leur utilisation
TR17624A (tr) 1-alkilidenaminourasiller,bunlarin hazirlanmasina mahsus usul ve bunlarin herbisid olarak kullanilmasi
IT1063143B (it) Procedimento per la preparazione del d,l pantolattone
NO142349C (no) Analogifremgangsmaate for fremstilling av terapeutisk virksomme 13-alkyl d-homogonadiener
NO144151C (no) Analogifremgangsmaate for fremstilling av 2,3-epoksyder med terapeutisk virkning

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7501114-8

Effective date: 19880125

Format of ref document f/p: F