SE324563B - - Google Patents
Info
- Publication number
- SE324563B SE324563B SE9014/66A SE901466A SE324563B SE 324563 B SE324563 B SE 324563B SE 9014/66 A SE9014/66 A SE 9014/66A SE 901466 A SE901466 A SE 901466A SE 324563 B SE324563 B SE 324563B
- Authority
- SE
- Sweden
- Prior art keywords
- butadiynyl
- pyranyloxy
- tetrahydro
- prepared
- steroids
- Prior art date
Links
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 6
- 150000003431 steroids Chemical class 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 4
- 229910052783 alkali metal Inorganic materials 0.000 abstract 3
- 150000001340 alkali metals Chemical class 0.000 abstract 3
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 2
- 229940093476 ethylene glycol Drugs 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- QZLYKIGBANMMBK-UGCZWRCOSA-N 5α-Androstane Chemical compound C([C@@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CCC[C@@]2(C)CC1 QZLYKIGBANMMBK-UGCZWRCOSA-N 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 1
- BUDQDWGNQVEFAC-UHFFFAOYSA-N Dihydropyran Chemical compound C1COC=CC1 BUDQDWGNQVEFAC-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 150000001350 alkyl halides Chemical class 0.000 abstract 1
- 230000029936 alkylation Effects 0.000 abstract 1
- 238000005804 alkylation reaction Methods 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- GRADOOOISCPIDG-UHFFFAOYSA-N buta-1,3-diyne Chemical group [C]#CC#C GRADOOOISCPIDG-UHFFFAOYSA-N 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000002009 diols Chemical class 0.000 abstract 1
- GRXPVLPQNMUNNX-MHJRRCNVSA-N estrane Chemical compound C1CC2CCCC[C@@H]2[C@@H]2[C@@H]1[C@@H]1CCC[C@@]1(C)CC2 GRXPVLPQNMUNNX-MHJRRCNVSA-N 0.000 abstract 1
- 150000002162 estranes Chemical class 0.000 abstract 1
- 230000001076 estrogenic effect Effects 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 238000001640 fractional crystallisation Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000016087 ovulation Effects 0.000 abstract 1
- 239000006187 pill Substances 0.000 abstract 1
- 230000001072 progestational effect Effects 0.000 abstract 1
- ODZPKZBBUMBTMG-UHFFFAOYSA-N sodium amide Chemical compound [NH2-].[Na+] ODZPKZBBUMBTMG-UHFFFAOYSA-N 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 abstract 1
- -1 tetrahydropyranyloxy groups Chemical group 0.000 abstract 1
- 238000004809 thin layer chromatography Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB28063/65A GB1074369A (en) | 1965-07-02 | 1965-07-02 | 17-alka-1',3'-diynyl)-steroids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE324563B true SE324563B (de) | 1970-06-08 |
Family
ID=10269672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9014/66A SE324563B (de) | 1965-07-02 | 1966-07-01 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US3463796A (de) |
| BE (1) | BE683345A (de) |
| BR (1) | BR6680929D0 (de) |
| CH (1) | CH481078A (de) |
| DE (1) | DE1568134C3 (de) |
| DK (2) | DK125420B (de) |
| FR (1) | FR1586807A (de) |
| GB (1) | GB1074369A (de) |
| IL (1) | IL25977A (de) |
| NL (1) | NL6609312A (de) |
| SE (1) | SE324563B (de) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB961502A (en) * | 1962-02-02 | 1964-06-24 | British Drug Houses Ltd | 17ª‡-butadiynyl-17ª‰-hydroxy steroids |
-
1965
- 1965-07-02 GB GB28063/65A patent/GB1074369A/en not_active Expired
-
1966
- 1966-06-16 IL IL25977A patent/IL25977A/xx unknown
- 1966-06-23 US US559737A patent/US3463796A/en not_active Expired - Lifetime
- 1966-06-28 FR FR1586807D patent/FR1586807A/fr not_active Expired
- 1966-06-29 DE DE1568134A patent/DE1568134C3/de not_active Expired
- 1966-06-29 BE BE683345D patent/BE683345A/xx unknown
- 1966-07-01 BR BR180929/66A patent/BR6680929D0/pt unknown
- 1966-07-01 DK DK341666AA patent/DK125420B/da unknown
- 1966-07-01 CH CH957766A patent/CH481078A/de not_active IP Right Cessation
- 1966-07-01 SE SE9014/66A patent/SE324563B/xx unknown
- 1966-07-04 NL NL6609312A patent/NL6609312A/xx unknown
-
1970
- 1970-10-06 DK DK508070AA patent/DK125087B/da unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL25977A (en) | 1969-11-30 |
| DE1568134B2 (de) | 1974-09-19 |
| BR6680929D0 (pt) | 1973-12-26 |
| DK125087B (da) | 1972-12-27 |
| CH481078A (de) | 1969-11-15 |
| DK125420B (da) | 1973-02-19 |
| DE1568134C3 (de) | 1975-05-22 |
| GB1074369A (en) | 1967-07-05 |
| FR1586807A (de) | 1970-03-06 |
| DE1568134A1 (de) | 1970-05-06 |
| NL6609312A (de) | 1967-01-03 |
| BE683345A (de) | 1966-12-01 |
| US3463796A (en) | 1969-08-26 |
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