GB1003802A
(en)
*
|
1963-06-04 |
1965-09-08 |
Searle & Co |
Pyrimidinone derivatives
|
GB1062357A
(en)
*
|
1965-03-23 |
1967-03-22 |
Pfizer & Co C |
Quinazolone derivatives
|
DE2027645A1
(de)
*
|
1970-06-05 |
1971-12-09 |
Byk Gulden Lomberg Chemische Fa bnk GmbH, 7750 Konstanz |
Piperazinylalkyl chinazolon (4) den vate, Verfahren zu deren Herstellung und sie enthaltende Arzneimittel
|
US3900476A
(en)
*
|
1973-05-17 |
1975-08-19 |
Upjohn Co |
2(2'-pyrimidylamino)quinazolines and their preparation
|
US3959279A
(en)
*
|
1974-01-28 |
1976-05-25 |
Sandoz, Inc. |
1-Substituted-2-imino-quinazolin-4(1H)ones
|
US3936453A
(en)
*
|
1974-01-28 |
1976-02-03 |
Sandoz, Inc. |
1-Substituted-2-disubstituted aminoquin azolin-4(1h)-ones
|
US4113637A
(en)
*
|
1974-09-10 |
1978-09-12 |
Institut Francais Du Petrole |
Alkyl-guanidino-heterocyclic compounds, their manufacture and use as additives for fuels and lubricants
|
GB8429739D0
(en)
*
|
1984-11-24 |
1985-01-03 |
Fbc Ltd |
Fungicides
|
US5756502A
(en)
*
|
1994-08-08 |
1998-05-26 |
Warner-Lambert Company |
Quinazolinone derivatives as cholyecystokinin (CCK) ligands
|
AU4858596A
(en)
*
|
1995-09-15 |
1997-04-01 |
Torrey Pines Institute For Molecular Studies |
Synthesis of quinazolinone libraries
|
US6258819B1
(en)
*
|
1999-08-05 |
2001-07-10 |
Syntex (U.S.A.) Llc |
Substituted 2(4-piperidyl)-4(3H)-quinazolinones and 2-(4-piperidyl)-4(3H)-azaquinazolinones
|
US7230000B1
(en)
*
|
1999-10-27 |
2007-06-12 |
Cytokinetics, Incorporated |
Methods and compositions utilizing quinazolinones
|
US6545004B1
(en)
|
1999-10-27 |
2003-04-08 |
Cytokinetics, Inc. |
Methods and compositions utilizing quinazolinones
|
US7671200B2
(en)
*
|
1999-10-27 |
2010-03-02 |
Cytokinetics, Inc. |
Quinazolinone KSP inhibitors
|
US6667300B2
(en)
*
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
SI2223922T1
(sl)
*
|
2000-04-25 |
2016-04-29 |
Icos Corporation |
Inhibitorji humane fosfatidil-inositol 3-kinazne delta izoforme
|
WO2002094790A1
(fr)
*
|
2001-05-23 |
2002-11-28 |
Mitsubishi Pharma Corporation |
Compose heterocyclique condense et son utilisation medicale
|
US7060705B2
(en)
|
2001-11-07 |
2006-06-13 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
US6753428B2
(en)
*
|
2001-11-20 |
2004-06-22 |
Cytokinetics, Inc. |
Process for the racemization of chiral quinazolinones
|
JP2005529076A
(ja)
*
|
2002-02-15 |
2005-09-29 |
サイトキネティクス・インコーポレーテッド |
キナゾリノンの合成
|
MXPA04011074A
(es)
*
|
2002-05-09 |
2005-06-08 |
Cytokinetics Inc |
Compuestos de pirimidinona, composiciones y metodos.
|
US7214800B2
(en)
|
2002-05-09 |
2007-05-08 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
US7038048B2
(en)
*
|
2002-05-23 |
2006-05-02 |
Cytokinetics, Inc. |
3H-pyridopyrimidin-4-one compounds, compositions, and methods of their use
|
CA2489367A1
(en)
*
|
2002-06-14 |
2003-12-24 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
AU2003256805A1
(en)
*
|
2002-07-23 |
2004-02-09 |
Cytokinetics, Inc. |
Compounds compositions and methods
|
WO2004018058A2
(en)
*
|
2002-08-21 |
2004-03-04 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
AU2003277079A1
(en)
*
|
2002-09-30 |
2004-05-04 |
Cytokinetics, Inc. |
Compounds, compositions, and methods
|
US20040242566A1
(en)
|
2003-03-25 |
2004-12-02 |
Syrrx, Inc. |
Dipeptidyl peptidase inhibitors
|
RU2006107553A
(ru)
*
|
2003-08-13 |
2007-09-20 |
Такеда Фармасьютикал Компани Лимитед (Jp) |
Производные 4-пиримидона и их применение в качестве ингибиторов пептидилпептидаз
|
US20050054614A1
(en)
*
|
2003-08-14 |
2005-03-10 |
Diacovo Thomas G. |
Methods of inhibiting leukocyte accumulation
|
US20050043239A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Jason Douangpanya |
Methods of inhibiting immune responses stimulated by an endogenous factor
|
WO2005030751A2
(en)
*
|
2003-09-08 |
2005-04-07 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
EP1699777B1
(en)
*
|
2003-09-08 |
2012-12-12 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
US20050197327A1
(en)
*
|
2003-11-03 |
2005-09-08 |
Gustave Bergnes |
Compounds, compositions, and methods
|
JP2007510660A
(ja)
*
|
2003-11-07 |
2007-04-26 |
サイトキネティクス・インコーポレーテッド |
化合物、組成物及び方法
|
JP2007513154A
(ja)
*
|
2003-12-08 |
2007-05-24 |
サイトキネティクス・インコーポレーテッド |
化合物、組成物及び方法
|
EA013427B1
(ru)
|
2004-03-15 |
2010-04-30 |
Такеда Фармасьютикал Компани Лимитед |
Ингибиторы дипептидилпептидазы
|
SI3153514T1
(sl)
|
2004-05-13 |
2022-02-28 |
Icos Corporation |
Kinazolinoni kot zaviralci človeške fosfatidilinozitol 3-kinaze delta
|
EP1755609A1
(en)
*
|
2004-05-25 |
2007-02-28 |
Icos Corporation |
Methods for treating and/or preventing aberrant proliferation of hematopoietic cells
|
EP1828192B1
(en)
|
2004-12-21 |
2014-12-03 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors
|
AU2006214190A1
(en)
*
|
2005-02-17 |
2006-08-24 |
Icos Corporation |
Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
|
DE102005024017A1
(de)
*
|
2005-05-25 |
2006-11-30 |
Merck Patent Gmbh |
Chinazolinone
|
PE20070622A1
(es)
*
|
2005-09-14 |
2007-08-22 |
Takeda Pharmaceutical |
Administracion de inhibidores de dipeptidil peptidasa
|
EP1942898B2
(en)
|
2005-09-14 |
2014-05-14 |
Takeda Pharmaceutical Company Limited |
Dipeptidyl peptidase inhibitors for treating diabetes
|
CN101360723A
(zh)
*
|
2005-09-16 |
2009-02-04 |
武田药品工业株式会社 |
制备嘧啶二酮衍生物的方法
|
US8349850B2
(en)
*
|
2006-03-28 |
2013-01-08 |
Atir Holding S.A. |
Heterocyclic compounds and uses thereof in the treatment of sexual disorders
|
JP2009531456A
(ja)
*
|
2006-03-28 |
2009-09-03 |
武田薬品工業株式会社 |
(r)−3−アミノピペリジン二塩酸塩の調製
|
BRPI0716971A2
(pt)
*
|
2006-09-13 |
2013-10-15 |
Takeda Pharmaceutical |
Uso de 2-6(3-amino-piperini-l-il)-3-metil-2,4-dioxo-3,4-dihidro-2 h-pirimidin-1ilmetil-4-fluoro-benxonitrila
|
US8324383B2
(en)
|
2006-09-13 |
2012-12-04 |
Takeda Pharmaceutical Company Limited |
Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
|
TW200838536A
(en)
*
|
2006-11-29 |
2008-10-01 |
Takeda Pharmaceutical |
Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
|
US8093236B2
(en)
|
2007-03-13 |
2012-01-10 |
Takeda Pharmaceuticals Company Limited |
Weekly administration of dipeptidyl peptidase inhibitors
|
US9492449B2
(en)
|
2008-11-13 |
2016-11-15 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
CN104042618B
(zh)
|
2008-11-13 |
2018-02-16 |
吉利德卡利斯托加公司 |
恶性血液病的治疗
|
CN102439012A
(zh)
|
2009-03-24 |
2012-05-02 |
吉里德卡利斯托加公司 |
2-嘌呤基-3-甲苯基-喹唑啉酮衍生物的阻转异构体和使用方法
|
EP2421536B1
(en)
*
|
2009-04-20 |
2015-08-26 |
Gilead Calistoga LLC |
Methods of treatment for solid tumors
|
CA2768843A1
(en)
|
2009-07-21 |
2011-01-27 |
Gilead Calistoga Llc |
Treatment of liver disorders with pi3k inhibitors
|
WO2012140642A1
(en)
|
2011-04-10 |
2012-10-18 |
Atir Holding S.A. |
Heterocyclic compounds and uses thereof in the treatment of sexual disorders
|
AR090253A1
(es)
|
2012-03-05 |
2014-10-29 |
Gilead Calistoga Llc |
Formas polimorficas de (s)-2-(1-(9h-purin-6-ilamino)propil)-5-fluor-3-fenilquinazolin-4(3h)-ona
|
MX2016008259A
(es)
|
2013-12-20 |
2016-10-13 |
Gilead Calistoga Llc |
Metodo de proceso para inhibidores de fosfatidilinositol 3-cinasa.
|
AU2014364414A1
(en)
|
2013-12-20 |
2016-06-30 |
Gilead Calistoga Llc |
Polymorphic forms of a hydrochloride salt of (S) -2-(1-(9H-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3H) -one
|
EP3154960A1
(en)
|
2014-06-13 |
2017-04-19 |
Gilead Sciences, Inc. |
Phosphatidylinositol 3-kinase inhibitors
|